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865783-95-5,MFCD31540462
Catalog No.:AA01ENRJ

865783-95-5 | ON-013100

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$140.00   $98.00
- +
5mg
95%
1 week  
$187.00   $131.00
- +
10mg
95%
1 week  
$261.00   $183.00
- +
25mg
95%
1 week  
$422.00   $296.00
- +
50mg
95%
1 week  
$644.00   $451.00
- +
100mg
95%
1 week  
$911.00   $638.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01ENRJ
Chemical Name:
ON-013100
CAS Number:
865783-95-5
Molecular Formula:
C19H22O7S
Molecular Weight:
394.4388
MDL Number:
MFCD31540462
SMILES:
COc1cc(OC)c(c(c1)OC)/C=C/S(=O)(=O)Cc1ccc(c(c1)O)OC
Properties
Computed Properties
 
Complexity:
557  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
8  
XLogP3:
2.6  

Literature

Title: Cho SY, et al. Determination of the glucuronide metabolite of ON 013100, a benzylstyrylsulfone antineoplastic drug, in colon cancer cells using LC/MS/MS. J Pharm Biomed Anal. 2013 Mar 5;75:138-44.

Title: Park IW, et al. Evaluation of novel cell cycle inhibitors in mantle cell lymphoma. Oncogene. 2007 Aug 16;26(38):5635-42.

Title: Neel Jasani, et al. Potent anticancer activity of an orally bioavailable small molecule, ON 013100, and its water soluble derivative, briciclib, a clinical-stage eIF4E-targeted agent. AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA.

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SDS
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