Name: Name:MK-3903
Brand: AABLOCKS
SKU: AA01ENTY
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA01ENTY

Chemical Name: MK-3903

CAS Number: 1219737-12-8

Molecular Formula: C27H19ClN2O3

Molecular Weight: 454.9044

MDL Number: MFCD22572341

SMILES: Clc1cc2nc([nH]c2cc1c1ccc(cc1)c1ccccc1)Oc1ccc(c(c1)C(=O)O)C

Properties

Complexity: 664

Covalently-Bonded Unit Count: 1

Heavy Atom Count: 33

Hydrogen Bond Acceptor Count: 4

Hydrogen Bond Donor Count: 2

Rotatable Bond Count: 5

XLogP3: 7.1

Downstream Synthesis Route

1219741-57-7

1219737-12-8

[1]CurrentPatentAssignee:MERCK&COINC-US2010/81643,2010,A1Locationinpatent:Page/Pagecolumn45

[2]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

[3]Feng,Danqing;Biftu,Tesfaye;Romero,F.Anthony;Kekec,Ahmet;Dropinski,James;Kassick,Andrew;Xu,Shiyao;Kurtz,MarcM.;Gollapudi,Anantha;Shao,Qing;Yang,Xiaodong;Lu,Ku;Zhou,Gaochao;Kemp,Daniel;Myers,RobertW.;Guan,Hong-Ping;Trujillo,MariaE.;Li,Cai;Weber,Ann;Sebhat,IyassuK.[ACSMedicinalChemistryLetters,2018,vol.9,#1,p.39-44]

1635-61-6

1219737-12-8

[1]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

[2]Feng,Danqing;Biftu,Tesfaye;Romero,F.Anthony;Kekec,Ahmet;Dropinski,James;Kassick,Andrew;Xu,Shiyao;Kurtz,MarcM.;Gollapudi,Anantha;Shao,Qing;Yang,Xiaodong;Lu,Ku;Zhou,Gaochao;Kemp,Daniel;Myers,RobertW.;Guan,Hong-Ping;Trujillo,MariaE.;Li,Cai;Weber,Ann;Sebhat,IyassuK.[ACSMedicinalChemistryLetters,2018,vol.9,#1,p.39-44]

335349-57-0

1219737-12-8

[1]JournalofMedicinalChemistry,2017,vol.60,p.9040-9052

[2]ACSMedicinalChemistryLetters,2018,vol.9,p.39-44

1219741-20-4

1219737-12-8

[1]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

[2]Feng,Danqing;Biftu,Tesfaye;Romero,F.Anthony;Kekec,Ahmet;Dropinski,James;Kassick,Andrew;Xu,Shiyao;Kurtz,MarcM.;Gollapudi,Anantha;Shao,Qing;Yang,Xiaodong;Lu,Ku;Zhou,Gaochao;Kemp,Daniel;Myers,RobertW.;Guan,Hong-Ping;Trujillo,MariaE.;Li,Cai;Weber,Ann;Sebhat,IyassuK.[ACSMedicinalChemistryLetters,2018,vol.9,#1,p.39-44]

1219741-21-5

1219737-12-8

[1]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

1219737-12-8 | MK-3903