Home Other Building Blocks 101803-03-6
101803-03-6,MFCD01631004
Catalog No.:AA0005JF
101803-03-6 | Guanosine, 2'-deoxy-N-ethyl-
This product is typically in stock,please click "Inquire" below or
contact us at sales@aablocks.com for pricing and availability information.
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Q & A
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0005JF
Chemical Name:
Guanosine, 2'-deoxy-N-ethyl-
CAS Number:
101803-03-6
Molecular Formula:
C12H17N5O4
Molecular Weight:
295.2945
MDL Number:
MFCD01631004
IUPAC Name:
2-(ethylamino)-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
InChI:
InChI=1S/C12H17N5O4/c1-2-13-12-15-10-9(11(20)16-12)14-5-17(10)8-3-6(19)7(4-18)21-8/h5-8,18-19H,2-4H2,1H3,(H2,13,15,16,20)/t6-,7+,8+/m0/s1
InChI Key:
VOKQFDULHQUWAV-XLPZGREQSA-N
SMILES:
CCNc1[nH]c(=O)c2c(n1)n(cn2)[C@H]1C[C@@H]([C@H](O1)CO)O
Properties
Computed Properties
 
Complexity:
445  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
295.128g/mol
Formal Charge:
0
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
295.299g/mol
Monoisotopic Mass:
295.128g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
121A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.1  

Synonyms
 
N(2)-ethyl-2'-deoxyguanosine 
N(2)-ethyl-dG 
n2-ethyldeoxyguanosine 
N2-Et-dG 
SCHEMBL6283863 
CTK4A0269 
DTXSID90572443 
HMS3263M12 
Tox21_501105 
ZINC43771712 
CCG-222409 
LP01105 
N(2)-ethyldeoxyguanosine 
NCGC00261790-01 
NCGC00485380-01 
J-000498 
N2-Ethyl-2 inverted exclamation marka-deoxyguanosine 
N2-Ethyl-2'-deoxyguanosine, >=98% (HPLC), solid 
2/'-Deoxy-N-ethylguanosine 
N2-ethyl-2'-deoxyguanosine 
N2-ethyl-dG 
N2-Ethyl-2'-deoxyguanosine 
101803-03-6 
2'-Deoxy-N-ethylguanosine 
Guanosine,2'-deoxy-N-ethyl- 
2-(Ethylamino)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one 
Literature

Title: Detection of acetaldehyde derived N(2)-ethyl-2'-deoxyguanosine in human leukocyte DNA following alcohol consumption.

Journal: Mutation research 20120901

Title: Time course of DNA adduct formation in peripheral blood granulocytes and lymphocytes after drinking alcohol.

Journal: Mutagenesis 20120701

Title: Acetaldehyde adducts in alcoholic liver disease.

Journal: Oxidative medicine and cellular longevity 20100101

Title: N2-ethyldeoxyguanosine as a potential biomarker for assessing effects of alcohol consumption on DNA.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20081101

Title: Differential blocking effects of the acetaldehyde-derived DNA lesion N2-ethyl-2'-deoxyguanosine on transcription by multisubunit and single subunit RNA polymerases.

Journal: The Journal of biological chemistry 20081010

Title: Increased DNA damage in ALDH2-deficient alcoholics.

Journal: Chemical research in toxicology 20061001

Title: Mutagenesis by exocyclic alkylamino purine adducts in Escherichia coli.

Journal: Mutation research 20060725

Title: Replication of N2-ethyldeoxyguanosine DNA adducts in the human embryonic kidney cell line 293.

Journal: Chemical research in toxicology 20060701

Title: Identification of an acetaldehyde adduct in human liver DNA and quantitation as N2-ethyldeoxyguanosine.

Journal: Chemical research in toxicology 20060201

Title: DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis.

Journal: Alcohol (Fayetteville, N.Y.) 20050401

Title: Miscoding potential of the N2-ethyl-2'-deoxyguanosine DNA adduct by the exonuclease-free Klenow fragment of Escherichia coli DNA polymerase I.

Journal: Biochemistry 20010403

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Additional Info:
Q & A
Related Products