Name: Name:2'-Deoxy-n2-dimethylaminomethylene-guanosine
Brand: AABLOCKS
SKU: AA001YP7
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA001YP7

Chemical Name: 2'-Deoxy-n2-dimethylaminomethylene-guanosine

CAS Number: 17331-13-4

Molecular Formula: C13H18N6O4

Molecular Weight: 322.3198

MDL Number: MFCD08704073

SMILES: OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2c1nc(N=CN(C)C)[nH]c2=O

Properties

Form: Solid

Storage: 2-8℃;Light sensitive;Inert atmosphere;

Complexity: 525

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 3

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 23

Hydrogen Bond Acceptor Count: 6

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 4

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 1

XLogP3: -0.3

Downstream Synthesis Route

40615-36-9

17331-13-4

40094-22-2

[1]Kung;Jones[TetrahedronLetters,1992,vol.33,#40,p.5869-5872]

[2]Vu,Huynh;McCollum,Christie;Jacobson,Karen;Theisen,Pete;Vinayak,Ravi;etal.[TetrahedronLetters,1990,vol.31,#50,p.7269-7272]

[3]CurrentPatentAssignee:COLUMBIAUNIVERSITYINTHECITYOFNEWYORK-WO2017/87887,2017,A1Locationinpatent:Page/Pagecolumn78;79

[4]CurrentPatentAssignee:COLUMBIAUNIVERSITYINTHECITYOFNEWYORK-WO2017/58953,2017,A1Locationinpatent:Paragraph0809;0811

[5]Arnold,Lubos;Tocik,Zdenek;Bradkova,Eliska;Hostomsky,Zdenek;Paces,Vaclav;Smrt,Jiri[CollectionofCzechoslovakChemicalCommunications,1989,vol.54,#2,p.523-532]

961-07-9

4637-24-5

17331-13-4

[1]Huang,Hai;Das,RajatS.;Basu,AshisK.;Stone,MichaelP.[JournaloftheAmericanChemicalSociety,2011,vol.133,#50,p.20357-20368]

[2]CurrentPatentAssignee:COLUMBIAUNIVERSITYINTHECITYOFNEWYORK-WO2017/87887,2017,A1Locationinpatent:Page/Pagecolumn78

[3]CurrentPatentAssignee:COLUMBIAUNIVERSITYINTHECITYOFNEWYORK-WO2017/58953,2017,A1Locationinpatent:Paragraph0809-0810

[4]Arnold,Lubos;Tocik,Zdenek;Bradkova,Eliska;Hostomsky,Zdenek;Paces,Vaclav;Smrt,Jiri[CollectionofCzechoslovakChemicalCommunications,1989,vol.54,#2,p.523-532]

[5]Vu,Huynh;McCollum,Christie;Jacobson,Karen;Theisen,Pete;Vinayak,Ravi;etal.[TetrahedronLetters,1990,vol.31,#50,p.7269-7272]

[6]McBride,LincolnJ.;Kierzek,Ryszard;Beaucage,SergeL.;Caruthers,MarvinH.[JournaloftheAmericanChemicalSociety,1986,vol.108,#8,p.2040-2048]

[7]Kung;Jones[TetrahedronLetters,1992,vol.33,#40,p.5869-5872]

[8]Grotli,Morten;Eritja,Ramon;Sproat,Brian[Tetrahedron,1997,vol.53,#33,p.11317-11346]

[9]Locationinpatent:experimentalpartMaier,Thomas;Pfleiderer,Wolfgang[HelveticaChimicaActa,2010,vol.93,#12,p.2365-2392]

[10]CurrentPatentAssignee:Deiters,Alexander-US8247540,2012,B2Locationinpatent:Page/Pagecolumn23

[11]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO;SCRIPPSRESEARCH-WO2019/200273,2019,A1Locationinpatent:Paragraph0313;0316

75-77-4

17331-13-4

N'-9-((2R,4S,5R)-4-Hydroxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl-N,N-dimethyl-formamidine

[1]Grotli,Morten;Eritja,Ramon;Sproat,Brian[Tetrahedron,1997,vol.53,#33,p.11317-11346]

17331-13-4 | 2'-Deoxy-n2-dimethylaminomethylene-guanosine