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103733-65-9,MFCD00144038
Catalog No.:AA007FRI

103733-65-9 | D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

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250mg
98%
in stock  
$6.00   $4.00
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1g
98%
in stock  
$7.00   $5.00
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5g
98%
in stock  
$15.00   $11.00
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10g
98%
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$28.00   $20.00
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25g
98%
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$57.00   $40.00
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100g
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$156.00   $110.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA007FRI
Chemical Name:
D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
CAS Number:
103733-65-9
Molecular Formula:
C10H11NO2
Molecular Weight:
177.1998
MDL Number:
MFCD00144038
SMILES:
OC(=O)[C@@H]1NCc2c(C1)cccc2
Properties
Computed Properties
 
Complexity:
205  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
-1.3  

Upstream Synthesis Route

[1]JournalofOrganicChemistry,2000,vol.65,#22,p.7310-7322

[1]MedChemComm,2014,vol.5,#9,p.1381-1383

[2]JournalofMedicinalChemistry,1988,vol.31,#11,p.2092-2097

[3]Patent:WO2004/72086,2004,A2,.Locationinpatent:Page182

[4]JournalofMedicinalChemistry,2010,vol.53,#15,p.5727-5737

[1]Synthesis,1992,#11,p.1157-1160

[1]Synthesis,1992,#11,p.1157-1160

[1]JournalofOrganicChemistry,2000,vol.65,#22,p.7310-7322

Downstream Synthesis Route

[1]MedChemComm,2014,vol.5,p.1381-1383

[2]JournalofMedicinalChemistry,1988,vol.31,p.2092-2097

[3]Patent:WO2004/72086,2004,A2.Locationinpatent:Page182

[4]JournalofMedicinalChemistry,2010,vol.53,p.5727-5737

[1]JournalofMedicinalChemistry,1988,vol.31,p.2092-2097

[1]BulletinoftheChemicalSocietyofJapan,1991,vol.64,p.3729-3731

[1]Synthesis,1992,p.1157-1160

[1]Synthesis,1992,p.1157-1160

Literature

Title: Capillary electrophoresis for diastereomers of (R,S)-tetrahydroisoquinoline-3-carboxylic acid derivatized with (R)-4-nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole: effect of molecular geometries.

Journal: Journal of chromatographic science 20050301

Title: Valle G, et al. Constrained phenylalanine analogues. Preferred conformation of the 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) residue. Int J Pept Protein Res. 1992 Sep-Oct;40(3-4):222-32.

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SDS
Tags:103733-65-9 Molecular Formula|103733-65-9 MDL|103733-65-9 SMILES|103733-65-9 D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid