Name: Name:5-(4-Hydroxybenzylidene)thiazolidine-2,4-dione
Brand: AABLOCKS
SKU: AA009742
Rating: 90 (10 reviews)

Catalog No.: AA009742

103788-60-9 | 5-(4-Hydroxybenzylidene)thiazolidine-2,4-dione

Pack Size： 1mg

Purity： >95%

1 week

$299.00 $209.00

Pack Size： 5mg

Purity： >95%

1 week

$319.00 $223.00

Pack Size： 500mg

Purity： >95%

1 week

$339.00 $238.00

Pack Size： 1g

Purity： >95%

1 week

$414.00 $290.00

Pack Size： 5g

Purity： >95%

1 week

$813.00 $569.00

Pack Size： 10g

Purity： >95%

1 week

$1,212.00 $848.00

Pack Size： 25g

Purity： >95%

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$2,408.00 $1,686.00

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Technical Information

Catalog Number: AA009742

Chemical Name: 5-(4-Hydroxybenzylidene)thiazolidine-2,4-dione

CAS Number: 103788-60-9

Molecular Formula: C10H7NO3S

Molecular Weight: 221.2325

MDL Number: MFCD00640639

SMILES: O=C1NC(=O)S/C/1=C/c1ccc(cc1)O

Properties

Complexity: 319

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 1

Formal Charge: 0

Heavy Atom Count: 15

Hydrogen Bond Acceptor Count: 4

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.8

Downstream Synthesis Route

103788-60-9

5221-37-4

(Z)-2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)-N-(pyridin-2-yl)acetamide

[1]EuropeanJournalofMedicinalChemistry,2010,vol.45,p.4539-4544

103788-60-9

1133819-87-0

[1]CurrentPatentAssignee:CIRIUSTHERAPEUTICS-WO2012/21476,2012,A1

[2]Tanis,StevenP.;Colca,JerryR.;Parker,TimothyT.;Artman,GeraldD.;Larsen,ScottD.;Gadwood,RobertC.;Zeller,JamesR.[TetrahedronLetters,2019,vol.60,#33]

103788-60-9

114772-40-6

1621471-01-9

[1]EuropeanJournalofMedicinalChemistry,2014,vol.83,p.129-140

103788-60-9

587-65-5

2-4-(2,4-dioxothiazolidin-5-ylidenemethyl)phenoxy-N-phenylacetamide

[1]Bhanushali,Umesh;Rajendran,Saranya;Sarma,Keerthana;Kulkarni,Pushkar;Chatti,Kiranam;Chatterjee,Suvro;Ramaa[BioorganicChemistry,2016,vol.67,p.139-147]

[2]Joshi,Hardik;Patil,Vijay;Tilekar,Kalpana;Upadhyay,Neha;Gota,Vikram;Ramaa[BioorganicandMedicinalChemistryLetters,2020,vol.30,#23]

103788-60-9

3289-75-6

N-(4-chlorophenyl)-2-4-(2,4-dioxothiazolidin-5-ylidenemethyl)phenoxyacetamide

[1]Bhanushali,Umesh;Rajendran,Saranya;Sarma,Keerthana;Kulkarni,Pushkar;Chatti,Kiranam;Chatterjee,Suvro;Ramaa[BioorganicChemistry,2016,vol.67,p.139-147]

[2]Joshi,Hardik;Patil,Vijay;Tilekar,Kalpana;Upadhyay,Neha;Gota,Vikram;Ramaa[BioorganicandMedicinalChemistryLetters,2020,vol.30,#23]

Literature fold

Title: Synthesis of O-prenylated and O-geranylated derivatives of 5-benzylidene2,4-thiazolidinediones and evaluation of their free radical scavenging activity as well as effect on some phase II antioxidant/detoxifying enzymes.

Journal: Bioorganic & medicinal chemistry letters20070301