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106392-48-7,MFCD31544351
Catalog No.:AA009T4T

106392-48-7 | ST271

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$21.00   $15.00
- +
5mg
98%
in stock  
$51.00   $36.00
- +
10mg
98%
in stock  
$65.00   $46.00
- +
50mg
98%
in stock  
$110.00   $77.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA009T4T
Chemical Name:
ST271
CAS Number:
106392-48-7
Molecular Formula:
C16H20N2O2
Molecular Weight:
272.3422
MDL Number:
MFCD31544351
SMILES:
CC(c1cc(/C=C(/C(=O)N)\C#N)cc(c1O)C(C)C)C
Properties
Computed Properties
 
Complexity:
413  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
3  

Downstream Synthesis Route

[1]ChemicalandPharmaceuticalBulletin,1988,vol.36,p.974-981

[1]ChemicalandPharmaceuticalBulletin,1988,vol.36,p.974-981

Literature

Title: [Tyrosine kinase inhibitor--hematological malignancies].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20010501

Title: Martinson EA, et al. Inhibition of phospholipase D of human platelets by protein tyrosine kinase inhibitors. Cell Mol Biol (Noisy-le-grand). 1994 Jul;40(5):627-34.

Title: Blake RA, et al. Fc gamma receptor II stimulated formation of inositol phosphates in human platelets is blocked by tyrosine kinase inhibitors and associated with tyrosine phosphorylation of the receptor.

Title: Uings IJ, et al. Tyrosine phosphorylation is involved in receptor coupling to phospholipase D but not phospholipase C in the human neutrophil. Biochem J. 1992 Feb 1;281 (Pt 3):597-600.

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SDS
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