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107220-28-0,MFCD01961045
Catalog No.:AA007ARD

107220-28-0 | Cevimeline hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$53.00   $37.00
- +
5mg
≥95%
in stock  
$140.00   $98.00
- +
10mg
≥95%
in stock  
$230.00   $161.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007ARD
Chemical Name:
Cevimeline hydrochloride
CAS Number:
107220-28-0
Molecular Formula:
C10H18ClNOS
Molecular Weight:
235.7740
MDL Number:
MFCD01961045
SMILES:
CC1SCC2(O1)CN1CCC2CC1.Cl
Properties
Computed Properties
 
Complexity:
215  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Undefined Atom Stereocenter Count:
2  

Literature

Title: Witsell DL, et al. Effectiveness of cevimeline to improve oral health in patients with postradiation xerostomia.Head Neck. 2012 Aug;34(8):1136-42. doi: 10.1002/hed.21894. Epub 2012 Jan 9.

Title: Kondo Y, et al.Cevimeline-induced monophasic salivation from the mouse submandibular gland: decreased Na+ content in saliva results from specific and early activation of Na+/H+ exchange.J Pharmacol Exp Ther. 2011 Apr;337(1):267-74. Epub 2011 Jan 14.

Title: Ono K, et al. Distinct effects of cevimeline and pilocarpine on salivary mechanisms, cardiovascular response and thirst sensation in rats.Arch Oral Biol. 2012 Apr;57(4):421-8. Epub 2011 Nov 17.

Title: Voskoboynik B, et al.Cevimeline (Evoxac) overdose.J Med Toxicol. 2011 Mar;7(1):57-9.

Title: Mitoh Y, et al. Effects of cevimeline on excitability of parasympathetic preganglionic neurons in the superior salivatory nucleus of rats. Auton Neurosci. 2017 Sep;206:1-7.

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