Catalog No.:AA007TAX

1092788-83-4 | PP121

Name: Name:PP121
Brand: AABLOCKS
SKU: AA007TAX
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5mg

98%

in stock

$45.00 $32.00

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10mg

98%

in stock

$65.00 $46.00

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Technical Information
Properties
Downstream Synthesis Route
Literature
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA007TAX

Chemical Name:

PP121

CAS Number:

1092788-83-4

Molecular Formula:

C17H17N7

Molecular Weight:

319.3638

MDL Number:

MFCD12912434

SMILES:

Nc1ncnc2c1c(nn2C1CCCC1)c1cnc2c(c1)cc[nH]2

Properties

Computed Properties

Complexity:

454

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

2.1

Downstream Synthesis Route

330794-31-5

754214-56-7

1-cyclopentyl-3-(1H-pyrrolo2,3-bpyridin-5-yl)-1H-pyrazolo3,4-dpyrimidin-4-amine

[1]ChemicalCommunications,2016,vol.52,p.14212-14214

330794-31-5

754214-56-7

271-63-6

1-cyclopentyl-3-(1H-pyrrolo2,3-bpyridin-5-yl)-1H-pyrazolo3,4-dpyrimidin-4-amine

[1]AngewandteChemie-InternationalEdition,2017,vol.56,p.6864-6868 Angew.Chem.,2017,vol.129,p.6968-6972,5

1092788-83-4

1450754-37-6

CASUnavailable

[1]Tong,Yuquan;Gibaut,QuentinM.R.;Rouse,Warren;Childs-Disney,JessicaL.;Suresh,BlessyM.;Abegg,Daniel;Choudhary,Shruti;Akahori,Yoshihiro;Adibekian,Alexander;Moss,WalterN.;Disney,MatthewD.[JournaloftheAmericanChemicalSociety,2022,vol.144,#26,p.11620-11625]

Literature

Title: Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases.

Journal: Nature chemical biology 20081101

Title: Apsel B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol, 2008, 4(11), 691-699.

Title: Peng Y, et al. The anti-esophageal cancer cell activity by a novel tyrosine/phosphoinositide kinase inhibitor PP121. Biochem Biophys Res Commun. 2015 Sep 11;465(1):137-44.

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SDS