[1]CurrentPatentAssignee:THEUNIVERSITYOFTOKYO;TOKYOUNIVERSITYOFSCIENCE-EP3312273,2018,A1Locationinpatent:Paragraph0132;0134
[2]CurrentPatentAssignee:TOKYOUNIVERSITYOFSCIENCE-EP3542821,2019,A1Locationinpatent:Paragraph0088;0154;0157
[3]CurrentPatentAssignee:TOKYOUNIVERSITYOFSCIENCE;THEUNIVERSITYOFTOKYO-EP3542824,2019,A1Locationinpatent:Paragraph0173-0174
[1]CurrentPatentAssignee:THEUNIVERSITYOFTOKYO;TOKYOUNIVERSITYOFSCIENCE-EP3312273,2018,A1
Title: Iron overload-induced calcium signals modulate mitochondrial fragmentation in HT-22 hippocampal neuron cells.
Journal: Toxicology 20160715
Title: Vialinin A is a ubiquitin-specific peptidase inhibitor.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Anti-malarial activity of new N-acetyl-L-leucyl-L-leucyl-L-norleucinal (ALLN) derivatives against Plasmodium falciparum.
Journal: Bioorganic & medicinal chemistry letters 20130301
Title: Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity.
Journal: Biochemical and biophysical research communications 20120622
Title: Degradation of mouse NTE-related esterase by macroautophagy and the proteasome.
Journal: Molecular biology reports 20120601
Title: Presenilin-2 regulates the degradation of RBP-Jk protein through p38 mitogen-activated protein kinase.
Journal: Journal of cell science 20120301
Title: Synthesis and evaluation of peptidyl α,β-unsaturated carbonyl derivatives as anti-malarial calpain inhibitors.
Journal: Archives of pharmacal research 20120301
Title: IRAK-1-mediated negative regulation of Toll-like receptor signaling through proteasome-dependent downregulation of TRAF6.
Journal: Biochimica et biophysica acta 20120201
Title: Stimulation of human formyl peptide receptors by calpain inhibitors: homology modeling of receptors and ligand docking simulation.
Journal: Archives of biochemistry and biophysics 20111215
Title: A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome.
Journal: Journal of cell science 20110815
Title: Hepatic autophagy mediates endoplasmic reticulum stress-induced degradation of misfolded apolipoprotein B.
Journal: Hepatology (Baltimore, Md.) 20110501
Title: Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability.
Journal: Oncogene 20110217
Title: Sur8/Shoc2 involves both inhibition of differentiation and maintenance of self-renewal of neural progenitor cells via modulation of extracellular signal-regulated kinase signaling.
Journal: Stem cells (Dayton, Ohio) 20110201
Title: Inhibition of the ubiquitin-proteasome system sensitizes TRAIL-resistant prostate cancer cells by up-regulation of death receptor 5.
Journal: Molecular medicine reports 20110101
Title: Calpain modulates capacitation and acrosome reaction through cleavage of the spectrin cytoskeleton.
Journal: Reproduction (Cambridge, England) 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Activation of mitochondrial calpain and release of apoptosis-inducing factor from mitochondria in RCS rat retinal degeneration.
Journal: Experimental eye research 20100901
Title: The production of 85 kDa N-terminal fragment of apolipoprotein B in mutant HepG2 cells generated by targeted modification of apoB gene occurs by ALLN-inhibitable protease cleavage during translocation.
Journal: Biochemical and biophysical research communications 20100806
Title: Extensive autolytic fragmentation of membranous versus cytosolic calpain following myocardial ischemia-reperfusion.
Journal: Canadian journal of physiology and pharmacology 20100501
Title: Targeted cancer stem cell therapies start with proper identification of the target.
Journal: Molecular cancer research : MCR 20100201
Title: Time-course correlation of early toxic events in three models of striatal damage: modulation by proteases inhibition.
Journal: Neurochemistry international 20100101
Title: Molecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpain.
Journal: PloS one 20100101
Title: Hypoxic resistance to articular chondrocyte apoptosis--a possible mechanism of maintaining homeostasis of normal articular cartilage.
Journal: The FEBS journal 20091201
Title: The C-terminal region of serotonin transporter is important for its trafficking and glycosylation.
Journal: Journal of pharmacological sciences 20091201
Title: Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly.
Journal: Nature medicine 20091001
Title: Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling.
Journal: Journal of lipid research 20090901
Title: Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1.
Journal: Molecular pharmacology 20090801
Title: Effects of dopamine on LC3-II activation as a marker of autophagy in a neuroblastoma cell model.
Journal: Neurotoxicology 20090701
Title: Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090601
Title: Antimalarial effect of N-acetyl-L-Leucyl-L-leucyl-L-norleucinal by the inhibition of Plasmodium falciparum Calpain.
Journal: Archives of pharmacal research 20090601
Title: Calpain-mediated degradation of G-substrate plays a critical role in retinal excitotoxicity for amacrine cells.
Journal: Journal of neuroscience research 20090501
Title: Decreased protein synthesis of Hsp27 associated with cellular toxicity in a cell model of Machado-Joseph disease.
Journal: Neuroscience letters 20090424
Title: Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1.
Journal: Cellular signalling 20090401
Title: HIV-1 Tat C-terminus is cleaved by calpain 1: implication for Tat-mediated neurotoxicity.
Journal: Biochimica et biophysica acta 20090201
Title: An ezrin/calpain/PI3K/AMPK/eNOSs1179 signaling cascade mediating VEGF-dependent endothelial nitric oxide production.
Journal: Circulation research 20090102
Title: Novel ENU-induced point mutation in scavenger receptor class B, member 1, results in liver specific loss of SCARB1 protein.
Journal: PloS one 20090101
Title: Proteasome affects the expression of aryl hydrocarbon receptor-regulated proteins.
Journal: Environmental toxicology and pharmacology 20081101
Title: Glutamate alteration of glutamic acid decarboxylase (GAD) in GABAergic neurons: the role of cysteine proteases.
Journal: Experimental neurology 20080901
Title: Synthesis and calpain inhibitory activity of peptidomimetic compounds with constrained amino acids at the P2 position.
Journal: Bioorganic & medicinal chemistry letters 20080901
Title: Oxidative stress and calpain inhibition induce alpha B-crystallin phosphorylation via p38-MAPK and calcium signalling pathways in H9c2 cells.
Journal: Cellular signalling 20080701
Title: Complex effects of IL1A polymorphism and calpain inhibitors on interleukin 1 alpha (IL-1 alpha) mRNA levels and secretion of IL-1 alpha protein.
Journal: Tissue antigens 20080701
Title: Autophagy modulates keratin-containing inclusion formation and apoptosis in cell culture in a context-dependent fashion.
Journal: Experimental cell research 20080501
Title: UBE1L represses PML/RAR{alpha} by targeting the PML domain for ISG15ylation.
Journal: Molecular cancer therapeutics 20080401
Title: Mycobacterium bovis bacillus Calmette-Guerin induces CCL5 secretion via the Toll-like receptor 2-NF-kappaB and -Jun N-terminal kinase signaling pathways.
Journal: Clinical and vaccine immunology : CVI 20080201
Title: Antioxidants block proteasome inhibitor function in endometrial carcinoma cells.
Journal: Anti-cancer drugs 20080201
Title: Down-regulation of brain-pancreas relative protein in diabetic rats and by high glucose in PC12 cells: prevention by calpain inhibitors.
Journal: Journal of pharmacological sciences 20080101
Title: Multiplexing bioluminescent and fluorescent reporters to monitor live cells.
Journal: Current chemical genomics 20080101
Title: Modulation of proteasome activity by vitamin E in THP-1 monocytes.
Journal: IUBMB life 20071201
Title: Babesia bovis: effects of cysteine protease inhibitors on in vitro growth.
Journal: Experimental parasitology 20071001
Title: Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-kappaB regulated gene products.
Journal: Blood 20071001
Title: Estrogen attenuates cardiac ischemia-reperfusion injury via inhibition of calpain-mediated bid cleavage.
Journal: Archives of pharmacal research 20071001
Title: Endothelial gap junctions are down-regulated by arsenic trioxide.
Journal: European journal of pharmacology 20070813
Title: Clostridium difficile toxin A-induced apoptosis is p53-independent but depends on glucosylation of Rho GTPases.
Journal: Apoptosis : an international journal on programmed cell death 20070801
Title: Oxidative stress induces the endoplasmic reticulum stress and facilitates inclusion formation in cultured cells.
Journal: Journal of hepatology 20070701
Title: Cleavage of focal adhesion kinase (FAK) is essential in adipocyte differentiation.
Journal: Biochemical and biophysical research communications 20070608
Title: Sterol regulatory element binding proteins downregulate LDL receptor-related protein (LRP1) expression and LRP1-mediated aggregated LDL uptake by human macrophages.
Journal: Cardiovascular research 20070601
Title: Involvement of NO/cGMP signaling in the apoptotic and anti-angiogenic effects of beta-lapachone on endothelial cells in vitro.
Journal: Journal of cellular physiology 20070501
Title: Regulation of plasma membrane Ca2+-ATPase in human platelets by calpain.
Journal: Platelets 20070501
Title: Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines.
Journal: Biochemical pharmacology 20070401
Title: Ischemia promotes calpain-mediated degradation of p120-catenin in SH-SY5Y cells.
Journal: Biochemical and biophysical research communications 20070216
Title: Lithium ions increase hepatic glycogen synthase stability through a proteasome-related mechanism.
Journal: Archives of biochemistry and biophysics 20070101
Title: The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention.
Journal: Molecular cancer 20070101
Title: Sp3 and sp4 transcription factor levels are increased in brains of patients with Alzheimer's disease.
Journal: Neuro-degenerative diseases 20070101
Title: Perturbed interactions of mutant proteolipid protein/DM20 with cholesterol and lipid rafts in oligodendroglia: implications for dysmyelination in spastic paraplegia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20061108
Title: [Effect of ubiquitin-proteasome pathway on inflammatory reaction in intestine and its barrier function in rats with postburn sepsis].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20061101
Title: Remodeling of connexin 43 in the diabetic rat heart.
Journal: Molecular and cellular biochemistry 20061001
Title: Albumin induces endoplasmic reticulum stress and apoptosis in renal proximal tubular cells.
Journal: Kidney international 20061001
Title: Multiple signaling pathways mediate compaction of collagen matrices by EGF-stimulated fibroblasts.
Journal: Experimental cell research 20060701
Title: In vivo heteromer formation. Expression of soluble betaA4-crystallin requires coexpression of a heteromeric partner.
Journal: The FEBS journal 20060701
Title: Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060701
Title: Differential regulation of eotaxin-1/CCL11 and eotaxin-3/CCL26 production by the TNF-alpha and IL-4 stimulated human lung fibroblast.
Journal: Biological & pharmaceutical bulletin 20060601
Title: Integrin alpha2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: identification of a novel signaling pathway.
Journal: The Journal of biological chemistry 20060331
Title: Overexpressed LEF-1 proteins display different nuclear localization patterns of beta-catenin in normal versus tumor cells.
Journal: Cell biology international 20060301
Title: Changes in tight junctional resistance of the cervical epithelium are associated with modulation of content and phosphorylation of occludin 65-kilodalton and 50-kilodalton forms.
Journal: Endocrinology 20060201
Title: Prodomain processing of recombinant plasmepsin II and IV, the aspartic proteases of Plasmodium falciparum, is auto- and trans-catalytic.
Journal: Journal of biochemistry 20060201
Title: The selective inhibition of nitric oxide production in the avian macrophage cell line HD11.
Journal: Veterinary immunology and immunopathology 20060115
Title: Degradation of perilipin is mediated through ubiquitination-proteasome pathway.
Journal: Biochimica et biophysica acta 20060101
Title: Involvement of calcium in 7beta -hydroxycholesterol and cholesterol-5beta,6beta -epoxide-induced apoptosis.
Journal: International journal of toxicology 20060101
Title: Hepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretion.
Journal: The Journal of biological chemistry 20051202
Title: Octanoate reduces very low-density lipoprotein secretion by decreasing the synthesis of apolipoprotein B in primary cultures of chicken hepatocytes.
Journal: Biochimica et biophysica acta 20051015
Title: Adeno-associated virus (AAV)-7 and -8 poorly transduce vascular endothelial cells and are sensitive to proteasomal degradation.
Journal: Gene therapy 20051001
Title: Activation of multiple pathways during photoreceptor apoptosis in the rd mouse.
Journal: Investigative ophthalmology & visual science 20051001
Title: Spliceosome-mediated RNA trans-splicing with recombinant adeno-associated virus partially restores cystic fibrosis transmembrane conductance regulator function to polarized human cystic fibrosis airway epithelial cells.
Journal: Human gene therapy 20050901
Title: Regulation of polymeric immunoglobulin receptor expression by reovirus.
Journal: The Journal of general virology 20050801
Title: Calcium-activated proteases are critical for refilling depleted vesicle stores in cultured sensory-motor synapses of Aplysia.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20050701
Title: Involvement of calpain in melanogenesis of mouse B16 melanoma cells.
Journal: Molecular and cellular biochemistry 20050701
Title: Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway.
Journal: The Journal of biological chemistry 20050513
Title: Antitumorigenic effect of proteasome inhibitors on insulinoma cells.
Journal: Endocrinology 20050401
Title: Corticosterone modulates noradrenaline-induced melatonin synthesis through inhibition of nuclear factor kappa B.
Journal: Journal of pineal research 20050401
Title: Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation.
Journal: Pigment cell research 20050401
Title: Dengue virus-induced apoptosis in hepatic cells is partly mediated by Apo2 ligand/tumour necrosis factor-related apoptosis-inducing ligand.
Journal: The Journal of general virology 20050401
Title: Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity.
Journal: Cancer research 20050301
Title: Participation of the ubiquitin-proteasome pathway in rat oocyte activation.
Journal: Zygote (Cambridge, England) 20050201
Title: The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism.
Journal: BMC cancer 20050101
Title: CD4 and CD8 T cell response to the rHSP60 from Klebsiella pneumoniae in peripheral blood mononuclear cells from patients with ankylosing spondylitis.
Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20050101
Title: Ubiquitin-proteasome pathway modulates mouse oocyte meiotic maturation and fertilization via regulation of MAPK cascade and cyclin B1 degradation.
Journal: Mechanisms of development 20041001
Title: Phosphorylation of the histone deacetylase 7 modulates its stability and association with 14-3-3 proteins.
Journal: The Journal of biological chemistry 20040813
Title: Inhibitors of cysteine cathepsin and calpain do not prevent ultraviolet-B-induced apoptosis in human keratinocytes and HeLa cells.
Journal: Archives of dermatological research 20040701
Title: Endoplasmic reticulum stress triggers an acute proteasome-dependent degradation of ATF6.
Journal: Journal of cellular biochemistry 20040701
Title: Transcriptional repression of E2F gene by proteasome inhibitors in human osteosarcoma cells.
Journal: Biochemical and biophysical research communications 20040611
Title: Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of beta-catenin and inhibition of beta-catenin-mediated transactivation.
Journal: International journal of molecular medicine 20040501
Title: Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040401
Title: Calpain inhibitors improve myocardial dysfunction and inflammation induced by endotoxin in rats.
Journal: Shock (Augusta, Ga.) 20040401
Title: Amino acid sequences within the beta1 domain of human apolipoprotein B can mediate rapid intracellular degradation.
Journal: Journal of lipid research 20040201
Title: Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein.
Journal: The Journal of biological chemistry 20040102
Title: Both insulin resistance and diabetes in Psammomys obesus upregulate the hepatic machinery involved in intracellular VLDL assembly.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040101
Title: Inhibition of apolipoprotein B secretion by taurocholate is controlled by the N-terminal end of the protein in rat hepatoma McArdle-RH7777 cells.
Journal: Biochimica et biophysica acta 20031230
Title: Calpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in adipocytes.
Journal: The Biochemical journal 20031215
Title: The mechanism of alphaB-crystallin gene expression by proteasome inhibition.
Journal: Biochemical and biophysical research communications 20031107
Title: Proteolysis of type I inositol 1,4,5-trisphosphate receptor in WB rat liver cells.
Journal: The Biochemical journal 20031101
Title: Inducible CD40 expression mediates NFkappaB activation and cytokine secretion in human colonic fibroblasts.
Journal: Gut 20031001
Title: Proteasome-mediated degradation of RNase L in response to phorbol-12-myristate-13-acetate (PMA) treatment of mouse L929 cells.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20031001
Title: Regulation of ubiquitous 6-phosphofructo-2-kinase by the ubiquitin-proteasome proteolytic pathway during myogenic C2C12 cell differentiation.
Journal: FEBS letters 20030828
Title: Radiosensitization by inhibition of IkappaB-alpha phosphorylation in human glioma cells.
Journal: Radiation research 20030801
Title: Ubiquitin-dependent and -independent proteasomal degradation of apoB associated with endoplasmic reticulum and Golgi apparatus, respectively, in HepG2 cells.
Journal: Journal of cellular biochemistry 20030801
Title: Effects of rewarming on nuclear factor-kappaB and interleukin 8 expression in cold-preserved alveolar epithelial cells.
Journal: Transplantation 20030727
Title: Food vacuole plasmepsins are processed at a conserved site by an acidic convertase activity in Plasmodium falciparum.
Journal: Molecular and biochemical parasitology 20030701
Title: Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines.
Journal: Molecular cancer research : MCR 20030701
Title: Transmembrane lipid transfer is crucial for providing neutral lipids during very low density lipoprotein assembly in endoplasmic reticulum.
Journal: The Journal of biological chemistry 20030613
Title: TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells.
Journal: Blood 20030501
Title: Modulation of ERG25 expression by LDL in vascular cells.
Journal: Cardiovascular research 20030401
Title: Factors affecting premature chromosome condensation of cumulus cell nuclei injected into rat oocytes.
Journal: The Journal of reproduction and development 20030401
Title: Dictyostelium differentiation-inducing factor-3 activates glycogen synthase kinase-3beta and degrades cyclin D1 in mammalian cells.
Journal: The Journal of biological chemistry 20030314
Title: I kappa B overexpression in cardiomyocytes prevents NF-kappa B translocation and provides cardioprotection in trauma.
Journal: American journal of physiology. Heart and circulatory physiology 20030301
Title: Role of BRCA1 in heat shock response.
Journal: Oncogene 20030109
Title: Inhibition of calpain is a component of nitric oxide-induced down-regulation of human mast cell adhesion.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030101
Title: Synergistic induction of apoptosis of rheumatoid arthritis synovial cells by H(2)O(2) and N-acetyl-leucyl-leucyl-norleucinal.
Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20030101
Title: Involvement of the proteasome in IL-1beta induced suppression of islets of Langerhans in the rat.
Journal: Upsala journal of medical sciences 20030101
Title: Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells.
Journal: Cancer biology & therapy 20030101
Title: Low-density lipoprotein upregulates low-density lipoprotein receptor-related protein expression in vascular smooth muscle cells: possible involvement of sterol regulatory element binding protein-2-dependent mechanism.
Journal: Circulation 20021210
Title: Signaling pathways for TNF production induced by human aminoacyl-tRNA synthetase-associating factor, p43.
Journal: Cytokine 20021124
Title: Activation of monocytic cells through Fc gamma receptors induces the expression of macrophage-inflammatory protein (MIP)-1 alpha, MIP-1 beta, and RANTES.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020915
Title: Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters.
Journal: Journal of lipid research 20020901
Title: Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells.
Journal: The Biochemical journal 20020801
Title: Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation.
Journal: The Journal of biological chemistry 20020621
Title: Ubiquitin/proteasome-dependent degradation of D-type cyclins is linked to tumor necrosis factor-induced cell cycle arrest.
Journal: The Journal of biological chemistry 20020510
Title: The time course of cardiac NF-kappaB activation and TNF-alpha secretion by cardiac myocytes after burn injury: contribution to burn-related cardiac contractile dysfunction.
Journal: Shock (Augusta, Ga.) 20020401
Title: Proteasomal degradation of retinoblastoma-related p130 during adipocyte differentiation.
Journal: Biochemical and biophysical research communications 20020125
Title: Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin.
Journal: EMBO reports 20020115
Title: Regulation of transformed state by calpastatin via PKCepsilon in NIH3T3 mouse fibroblasts.
Journal: Biochemical and biophysical research communications 20020111
Title: Green tea catechins decrease apolipoprotein B-100 secretion from HepG2 cells.
Journal: Molecular and cellular biochemistry 20020101
Title: Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation.
Journal: Neuron 20011220
Title: Activation of caspase-8 during N-(4-hydroxyphenyl)retinamide-induced apoptosis in Fas-defective hepatoma cells.
Journal: Hepatology (Baltimore, Md.) 20011201
Title: Proteasome-mediated degradation of BRCA1 protein in MCF-7 human breast cancer cells.
Journal: International journal of oncology 20011001
Title: Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein.
Journal: The EMBO journal 20011001
Title: Evidence for the Involvement of annexin 6 in the trafficking between the endocytic compartment and lysosomes.
Journal: Experimental cell research 20010910
Title: Proteasome inhibitors induce Fas-mediated apoptosis by c-Myc accumulation and subsequent induction of FasL message in human glioma cells.
Journal: FEBS letters 20010824
Title: Dendritic growth induced by BMP-7 requires Smad1 and proteasome activity.
Journal: Journal of neurobiology 20010801
Title: Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway.
Journal: The Journal of biological chemistry 20010629
Title: Impairment of the ubiquitin-proteasome system by protein aggregation.
Journal: Science (New York, N.Y.) 20010525
Title: The role of NF-kappa B in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of melanoma cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010501
Title: 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: balance between transcriptional and posttranscriptional regulation.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20010501
Title: Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIalpha expression.
Journal: Biochemical pharmacology 20010401
Title: Peptide transport by the multidrug resistance protein MRP1.
Journal: Cancer research 20010315
Title: A mutation of the Wilson disease protein, ATP7B, is degraded in the proteasomes and forms protein aggregates.
Journal: Gastroenterology 20010301
Title: LDL downregulates CYP51 in porcine vascular endothelial cells and in the arterial wall through a sterol regulatory element binding protein-2-dependent mechanism.
Journal: Circulation research 20010216
Title: Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance.
Journal: Circulation 20010102
Title: Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons.
Journal: Neuroscience 20010101
Title: Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid.
Journal: Journal of lipid research 20001201
Title: Peptide aldehydes as inhibitors of HIV protease.
Journal: FEBS letters 19930322
Title: Stimulation of N-terminal truncated isoform of androgen receptor stabilizes human ether-á-go-go-related gene-encoded potassium channel protein via activation of extracellular signal regulated kinase 1/2.
Journal: Endocrinology