[1]JournalofMedicinalChemistry,1987,vol.30,#11,p.1984-1991
[1]JournalofMedicinalChemistry,1987,vol.30,#11,p.1984-1991
[1]JournalofMedicinalChemistry,1987,vol.30,#11,p.1984-1991
[1]JournalofMedicinalChemistry,1987,vol.30,#11,p.1984-1991
[1]JournalofMedicinalChemistry,1987,vol.30,#11,p.1984-1991
[1]JournalofMedicinalChemistry,1987,vol.30,p.1984-1991
[1]JournalofMedicinalChemistry,1987,vol.30,p.1984-1991
[1]JournalofMedicinalChemistry,1987,vol.30,p.1984-1991
[1]JournalofMedicinalChemistry,1987,vol.30,p.1984-1991
[1]JournalofMedicinalChemistry,1987,vol.30,p.1984-1991
Title: Evaluation of transport mechanism of prodrugs and parent drugs formed by intracellular metabolism in Caco-2 cells with modified carboxylesterase activity: temocapril as a model case.
Journal: Journal of pharmaceutical sciences 20110901
Title: Prediction of human intestinal absorption of the prodrug temocapril by in situ single-pass perfusion using rat intestine with modified hydrolase activity.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701
Title: [A ten-year follow-up of a 109-year-old woman with myocardial infarction].
Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20110101
Title: [Role of angiontensin receptors in remodeling perivascular nerves].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101101
Title: The effect of angiotensin-converting enzyme inhibitors of left atrial pressure in dogs with mitral valve regurgitation.
Journal: Journal of veterinary internal medicine 20100101
Title: Effect of angiotensin-converting enzyme inhibitor on serum asymmetric dimethylarginine and coronary circulation in patients with type 2 diabetes mellitus.
Journal: International journal of cardiology 20090220
Title: Olmesartan and temocapril prevented the development of hyperglycemia and the deterioration of pancreatic islet morphology in Otsuka-Long-Evans-Tokushima Fatty rats.
Journal: Acta medica Okayama 20090201
Title: In half of hypertensive diabetics, co-administration of a calcium channel blocker and an angiotensin-converting enzyme inhibitor achieved a target blood pressure of <130/80 mmHg: the azelnidipine and temocapril in hypertensive patients with type 2 diabetes (ATTEST) study.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080801
Title: Beneficial effects of olmesartan and temocapril on urinary liver-type fatty acid-binding protein levels in normotensive patients with immunoglobin A nephropathy.
Journal: American journal of hypertension 20071101
Title: Effects of monotherapy of temocapril or candesartan with dose increments or combination therapy with both drugs on the suppression of diabetic nephropathy.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20070401
Title: Aldosterone breakthrough during therapy with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in proteinuric patients with immunoglobulin A nephropathy.
Journal: Nephrology (Carlton, Vic.) 20061001
Title: Angiotensin I-converting enzyme inhibitor improves reactive hyperemia in elderly hypertensives with arteriosclerosis obliterans.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20060901
Title: Nephrotic syndrome and IgA nephropathy in polycystic kidney disease.
Journal: Clinical and experimental nephrology 20060601
Title: Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril.
Journal: Clinical pharmacology and therapeutics 20060501
Title: Effect on coronary flow velocity reserve in patients with type 2 diabetes mellitus: comparison between angiotensin-converting enzyme inhibitor and angiotensin II type 1 receptor antagonist.
Journal: American heart journal 20060401
Title: Angiotensin converting enzyme inhibitor attenuates oxidative stress-induced endothelial cell apoptosis via p38 MAP kinase inhibition.
Journal: Clinica chimica acta; international journal of clinical chemistry 20060201
Title: Identification of esterases expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050801
Title: Renin-angiotensin system modulates oxidative stress-induced endothelial cell apoptosis in rats.
Journal: Hypertension (Dallas, Tex. : 1979) 20050601
Title: Dual ECE/NEP inhibition on cardiac and neurohumoral function during the transition from hypertrophy to heart failure in rats.
Journal: Hypertension (Dallas, Tex. : 1979) 20050601
Title: Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers effectively and directly potentiate superoxide scavenging by polymorphonuclear leukocytes from patients with type 2 diabetes mellitus.
Journal: The American journal of the medical sciences 20050501
Title: Long-term inhibition of angiotensin prevents reduction of periarterial innervation of calcitonin gene-related peptide (CGRP)-containing nerves in spontaneously hypertensive rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20050501
Title: Endothelium-derived hydrogen peroxide accounts for the enhancing effect of an angiotensin-converting enzyme inhibitor on endothelium-derived hyperpolarizing factor-mediated responses in mice.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050401
Title: Different accumulation of temocapril and enalapril during repeated dosing in elderly patients.
Journal: British journal of clinical pharmacology 20050401
Title: Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats.
Journal: Journal of the American Society of Nephrology : JASN 20050301
Title: Angiotensin-converting-enzyme inhibitors slow renal decline in IgA nephropathy, independent of tubulointerstitial fibrosis at presentation.
Journal: QJM : monthly journal of the Association of Physicians 20050301
Title: ACE inhibitor and angiotensin II type 1 receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure.
Journal: Journal of hypertension 20050201
Title: Exercise-related syncope induced by vasodilator therapy in an elderly hypertensive patient.
Journal: Journal of the American Geriatrics Society 20050201
Title: Insulin sensitivity and endothelial function in hypertension: a comparison of temocapril and candesartan.
Journal: American journal of hypertension 20050201
Title: Renal artery stenosis emerged after angiotensin-converting enzyme inhibitor treatment for myocardial infarction: a case report.
Journal: Angiology 20050101
Title: Low-dose combination therapy with temocapril and losartan reduces proteinuria in normotensive patients with immunoglobulin a nephropathy.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20041201
Title: Blockade of the renin-angiotensin system decreases adipocyte size with improvement in insulin sensitivity.
Journal: Journal of hypertension 20041001
Title: Additive beneficial effects of the combination of a calcium channel blocker and an angiotensin blocker on a hypertensive rat-heart failure model.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20041001
Title: Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040901
Title: Salutary effects of attenuation of angiotensin II on coronary perivascular fibrosis associated with insulin resistance and obesity.
Journal: Journal of molecular and cellular cardiology 20040801
Title: Renoprotective effect of angiotensin-converting enzyme inhibitor combined with alpha1-adrenergic antagonist in spontaneously hypertensive rats with renal ablation.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20040701
Title: AT1 receptor blocker added to ACE inhibitor provides benefits at advanced stage of hypertensive diastolic heart failure.
Journal: Hypertension (Dallas, Tex. : 1979) 20040301
Title: Regulation of skeletal muscle peroxisome proliferator-activated receptor gamma expression by exercise and angiotensin-converting enzyme inhibition in fructose-fed hypertensive rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20040101
Title: Comparison of urinary excretion of pravastatin and temocapril in bile duct-ligated rats and Eisai hyperbilirubinemic rats (EHBR).
Journal: Journal of hepato-biliary-pancreatic surgery 20040101
Title: Pharmacological and clinical studies with temocapril, an angiotensin converting enzyme inhibitor that is excreted in the bile.
Journal: Cardiovascular drug reviews 20040101
Title: Effects of exercise training on glomerular structure in fructose-fed spontaneously hypertensive rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20031101
Title: Successful treatment of severe hypertension with the combination of angiotensin converting enzyme inhibitor and angiotensin II receptor blocker.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20031001
Title: A newly developed angiotensin II type 1 receptor antagonist, CS866, promotes regression of cardiac hypertrophy by reducing integrin beta1 expression.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030901
Title: Evaluation of systemic blood NO dynamics by EPR spectroscopy: HbNO as an endogenous index of NO.
Journal: American journal of physiology. Heart and circulatory physiology 20030801
Title: Human-derived vascular smooth muscle cells produce angiotensin II by changing to the synthetic phenotype.
Journal: Journal of cellular physiology 20030801
Title: Beneficial effects of angiotensin-converting enzyme inhibition on sarcoplasmic reticulum function in the failing heart of the Dahl rat.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20030801
Title: Efficacy of various antihypertensive agents as evaluated by indices of vascular stiffness in elderly hypertensive patients.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030801
Title: Blockade of the renin-angiotensin system increases adiponectin concentrations in patients with essential hypertension.
Journal: Hypertension (Dallas, Tex. : 1979) 20030701
Title: Should increasing the dose or adding an AT1 receptor blocker follow a relatively low dose of ACE inhibitor initiated in acute myocardial infarction?
Journal: Cardiovascular research 20030601
Title: Temocapril treatment ameliorates autoimmune myocarditis associated with enhanced cardiomyocyte thioredoxin expression.
Journal: Molecular and cellular biochemistry 20030601
Title: [Temocapril treatment upregulated cardiomyocyte thioredoxin expression and improved autoimmune myocarditis].
Journal: Zhonghua nei ke za zhi 20030501
Title: Temocapril prevents motor neuron damage and upregulation of cyclooxygenase-II in glutamate-induced neurotoxicity.
Journal: Neurological research 20030401
Title: Chronic angiotensin II inhibition increases levels of calcitonin gene-related peptide mRNA of the dorsal root ganglia in spontaneously hypertensive rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030301
Title: Effects of angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on beta-adrenoceptor signaling in heart failure produced by myocardial Infarction in rabbits: reversal of altered expression of beta-adrenoceptor kinase and G i alpha.
Journal: The Journal of pharmacology and experimental therapeutics 20030101
Title: Beneficial effects of combination of ACE inhibitor and angiotensin II type 1 receptor blocker on cardiac remodeling in rat myocardial infarction.
Journal: Cardiovascular research 20030101
Title: Effects of temocapril and olmesartan on myocardial sympathetic nervous activity and fatty acid metabolism in rats with chronic beta-adrenergic stimulation.
Journal: Journal of cardiovascular pharmacology 20030101
Title: [Successful treatment of combination therapy using an angiotensin-converting enzyme inhibitor and an angiotensin II receptor blocker in a patient with IgA nephropathy].
Journal: Nihon Jinzo Gakkai shi 20030101
Title: Antiproteinuric effects of combined antihypertensive therapies in patients with overt type 2 diabetic nephropathy.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20021101
Title: Impact of exercise and angiotensin converting enzyme inhibition on tumor necrosis factor-alpha and leptin in fructose-fed hypertensive rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20021101
Title: Chronic angiotensin-converting enzyme inhibition and angiotensin II antagonism in rats with chronic renal failure.
Journal: Journal of cardiovascular pharmacology 20021001
Title: An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats.
Journal: Journal of vascular surgery 20021001
Title: CS-886, a new angiotensin II type 1 receptor antagonist, ameliorates glomerular anionic site loss and prevents progression of diabetic nephropathy in Otsuka Long-Evans Tokushima fatty rats.
Journal: Molecular medicine (Cambridge, Mass.) 20021001
Title: ACE inhibitor improves insulin resistance in diabetic mouse via bradykinin and NO.
Journal: Hypertension (Dallas, Tex. : 1979) 20020901
Title: Inhibition of renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20020901
Title: [Effects of temocapril on the prevention of early diabetic nephropathy in OLETF rat, an animal model for type 2 diabetes].
Journal: [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20020901
Title: Beneficial effects of combined blockade of ACE and AT1 receptor on intimal hyperplasia in balloon-injured rat artery.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20020801
Title: Combination therapy of exercise and angiotensin-converting enzyme inhibitor markedly improves insulin sensitivities in hypertensive patients with insulin resistance.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20020701
Title: Differential effects of a long-acting angiotensin converting enzyme inhibitor (temocapril) and a long-acting calcium antagonist (amlodipine) on ventricular ectopic beats in older hypertensive patients.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20020501
Title: Combination therapy with an angiotensin-converting enzyme (ACE) inhibitor and a calcium antagonist: beyond the renoprotective effects of ACE inhibitor monotherapy in a spontaneous hypertensive rat with renal ablation.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20020501
Title: Combined effect of ACE inhibitor and exercise training on insulin resistance in type 2 diabetic rats.
Journal: Life sciences 20020301
Title: Inhibitory effect of a novel angiotensin II type 1 receptor antagonist RNH-6270 on growth of vascular smooth muscle cells from spontaneously hypertensive rats: different anti-proliferative effect to angiotensin-converting enzyme inhibitor.
Journal: Journal of cardiovascular pharmacology 20020201
Title: Temocapril, a long-acting non-SH group angiotensin converting enzyme inhibitor, modulates glomerular injury in chronic puromycin aminonucleoside nephrosis.
Journal: Journal of nephrology 20020101
Title: [Effects of CS-866, an angiotensin II receptor antagonist, in 5/6 nephrectomized spontaneously hypertensive rats].
Journal: Nihon Jinzo Gakkai shi 20011001
Title: Effects of long-acting ACE inhibitor (temocapril) and long-acting Ca channel blocker (amlodipine) on 24-h ambulatory BP in elderly hypertensive patients.
Journal: Journal of human hypertension 20010901
Title: Differential subcellular actions of ACE inhibitors and AT(1) receptor antagonists on cardiac remodeling induced by chronic inhibition of NO synthesis in rats.
Journal: Hypertension (Dallas, Tex. : 1979) 20010901
Title: Differential effects of angiotensin II versus endothelin-1 inhibitions in hypertrophic left ventricular myocardium during transition to heart failure.
Journal: Circulation 20010731
Title: Angiotensin-converting enzyme inhibition attenuates hypofibrinolysis and reduces cardiac perivascular fibrosis in genetically obese diabetic mice.
Journal: Circulation 20010626
Title: Angiotensin blockade inhibits increased JNKs, AP-1 and NF- kappa B DNA-binding activities in myocardial infarcted rats.
Journal: Journal of molecular and cellular cardiology 20010401
Title: Effects of troglitazone and temocapril in spontaneously hypertensive rats with chronic renal failure.
Journal: Journal of hypertension 20010301
Title: Effect of temocapril hydrochloride on serum lipid levels in patients with hypertensive type 2 diabetes mellitus.
Journal: Journal of atherosclerosis and thrombosis 20010101
Title: Prevention of doxorubicin (adriamycin)-induced cardiomyopathy by simultaneous administration of angiotensin-converting enzyme inhibitor assessed by acoustic densitometry.
Journal: Journal of cardiovascular pharmacology 20000901
Title: Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver.
Journal: Biological & pharmaceutical bulletin 19970801
Title: Pharmacokinetics of temocapril, an ACE inhibitor with preferential biliary excretion, in patients with impaired liver function.
Journal: European journal of clinical pharmacology 19930101
Title: Pharmacokinetics of temocapril hydrochloride, a novel angiotensin converting enzyme inhibitor, in renal insufficiency.
Journal: European journal of clinical pharmacology 19920101
