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22214-42-2,MFCD00012210
Catalog No.:AA01DFAY

22214-42-2 | (E)-4-(4-Hydroxy-3-methoxyphenyl)but-3-en-2-one

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5g
>98.0%(GC)
in stock  
$86.00   $60.00
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25g
>98.0%(GC)
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$248.00   $174.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01DFAY
Chemical Name:
(E)-4-(4-Hydroxy-3-methoxyphenyl)but-3-en-2-one
CAS Number:
22214-42-2
Molecular Formula:
C11H12O3
Molecular Weight:
192.2112
MDL Number:
MFCD00012210
SMILES:
COc1cc(C=CC(=O)C)ccc1O
FEMA Number:
3738
Properties
Computed Properties
 
Complexity:
223  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
Undefined Bond Stereocenter Count:
1  
XLogP3:
1.7  

Literature

Title: Synthesis of substituted benzimidazolyl curcumin mimics and their anticancer activity.

Journal: Bioorganic & medicinal chemistry letters 20120115

Title: Characterization of raspberry ketone/zingerone synthase, catalyzing the alpha, beta-hydrogenation of phenylbutenones in raspberry fruits.

Journal: Biochemical and biophysical research communications 20110819

Title: Autoxidative and cyclooxygenase-2 catalyzed transformation of the dietary chemopreventive agent curcumin.

Journal: The Journal of biological chemistry 20110114

Title: Stabilization of curcumin by complexation with divalent cations in glycerol/water system.

Journal: Bioinorganic chemistry and applications 20100101

Title: The neuroprotective effects of benzylideneacetophenone derivatives on excitotoxicity and inflammation via phosphorylated Janus tyrosine kinase 2/phosphorylated signal transducer and activator of transcription 3 and mitogen-activated protein K pathways.

Journal: The Journal of pharmacology and experimental therapeutics 20090201

Title: Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature.

Journal: Biochemical pharmacology 20081201

Title: Molecular and biochemical characterization of benzalacetone synthase and chalcone synthase genes and their proteins from raspberry (Rubus idaeus L.).

Journal: Archives of biochemistry and biophysics 20080215

Title: Differential solubility of curcuminoids in serum and albumin solutions: implications for analytical and therapeutic applications.

Journal: BMC biotechnology 20080101

Title: Curcumin and dehydrozingerone derivatives: synthesis, radiolabeling, and evaluation for beta-amyloid plaque imaging.

Journal: Journal of medicinal chemistry 20061005

Title: Identification of natural dyes used in works of art by pyrolysis-gas chromatography/mass spectrometry combined with in situ trimethylsilylation.

Journal: Analytical and bioanalytical chemistry 20050501

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Tags:22214-42-2 Molecular Formula|22214-42-2 MDL|22214-42-2 SMILES|22214-42-2 (E)-4-(4-Hydroxy-3-methoxyphenyl)but-3-en-2-one