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Title: Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
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Title: Metabolic profiling detects biomarkers of protein degradation in COPD patients.
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Title: Sex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in the lung epithelium of smokers.
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Title: Glycine and its N-methylated analogues cause pH-dependent membrane damage to enterotoxigenic Escherichia coli.
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Title: A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy.
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Title: Imidazolopiperazines: lead optimization of the second-generation antimalarial agents.
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Title: Experimental and theoretical enthalpies of formation of glycine-based sulfate/bisulfate amino acid ionic liquids.
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Title: Variability of plasma and urine betaine in diabetes mellitus and its relationship to methionine load test responses: an observational study.
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Title: Dietary N,N-dimethylglycine supplementation improves nutrient digestibility and attenuates pulmonary hypertension syndrome in broilers.
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Title: CGDEase, a Pseudomonas fluorescens protein of the PLC/APase superfamily with CDP-ethanolamine and (dihexanoyl)glycerophosphoethanolamine hydrolase activity induced by osmoprotectants under phosphate-deficient conditions.
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Title: NMR-based metabolomic studies on the toxicological effects of cadmium and copper on green mussels Perna viridis.
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Title: Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria.
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Title: The Saccharomyces cerevisiae Genes, AIM45, YGR207c/CIR1 and YOR356w/CIR2, Are Involved in Cellular Redox State Under Stress Conditions.
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Title: Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males.
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Title: An internal reaction chamber in dimethylglycine oxidase provides efficient protection from exposure to toxic formaldehyde.
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Title: Manipulation of sinapine, choline and betaine accumulation in Arabidopsis seed: towards improving the nutritional value of the meal and enhancing the seedling performance under environmental stresses in oilseed crops.
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Title: The purified recombinant precursor of rat mitochondrial dimethylglycine dehydrogenase binds FAD via an autocatalytic reaction.
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Title: Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
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Title: A genome-scale metabolic reconstruction of Pseudomonas putida KT2440: iJN746 as a cell factory.
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Title: The salt-induced ABC transporter Ota of the methanogenic archaeon Methanosarcina mazei Gö1 is a glycine betaine transporter.
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Title: The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.
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Title: Sex differences in the control of plasma concentrations and urinary excretion of glycine betaine in patients attending a lipid disorders clinic.
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Title: Metabolism of low-dose inorganic arsenic in a central European population: influence of sex and genetic polymorphisms.
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Title: Osmotic regulation of betaine homocysteine-S-methyltransferase expression in H4IIE rat hepatoma cells.
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Title: Mechanistic aspects and redox properties of hyperthermophilic L-proline dehydrogenase from Pyrococcus furiosus related to dimethylglycine dehydrogenase/oxidase.
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Title: The organic osmolytes betaine and proline are transported by a shared system in early preimplantation mouse embryos.
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Title: Characterization of oxysterols by electrospray ionization tandem mass spectrometry after one-step derivatization with dimethylglycine.
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Title: Immunomodulation of murine collagen-induced arthritis by N, N-dimethylglycine and a preparation of Perna canaliculus.
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Title: Effects of substrate and potassium on the betaine-synthesizing enzyme glycine sarcosine dimethylglycine N-methyltransferase from a halophilic methanoarchaeon Methanohalophilus portucalensis.
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Title: Critical active-site residues identified by site-directed mutagenesis in Pseudomonas aeruginosa phosphorylcholine phosphatase, a new member of the haloacid dehalogenases hydrolase superfamily.
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Title: Mechanism of FAD reduction and role of active site residues His-225 and Tyr-259 in Arthrobacter globiformis dimethylglycine oxidase: analysis of mutant structure and catalytic function.
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Title: Heterotetrameric sarcosine oxidase: structure of a diflavin metalloenzyme at 1.85 A resolution.
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Title: Mild and nonracemizing conditions for Ullmann-type diaryl ether formation between aryl iodides and tyrosine derivatives.
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Title: The effects of the oral, pan-VEGF-R kinase inhibitor CEP-7055 and chemotherapy in orthotopic models of glioblastoma and colon carcinoma in mice.
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Title: Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides.
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Title: N,N-dimethyl-beta-alanine as an inexpensive and efficient ligand for palladium-catalyzed Heck reaction.
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Title: Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver.
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Title: Treatment for mitochondrial disorders.
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Title: Causes of hyperhomocysteinemia in patients with chronic kidney diseases.
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Title: Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies.
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Title: In silico experimentation with a model of hepatic mitochondrial folate metabolism.
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Title: Weak antiferromagnetic interactions in hydronium diaqua-1kappaO,2kappaO-trichloro-1kappaCl,2kappa2Cl-mu-dimethylglycinato-1kappaO:2kappa2O',N-dimethylglycinato-1kappa2N,O-dicuprate(II).
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Title: NMR spectroscopic-based metabonomic investigation on the acute biochemical effects induced by Ce(NO3)3 in rats.
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Title: Stabilization of non-productive conformations underpins rapid electron transfer to electron-transferring flavoprotein.
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Title: Gas phase synthesis and reactivity of Agn+ and Ag(n-1)H+ cluster cations.
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Title: Sexual dimorphism in urinary metabolite profiles of Han Wistar rats revealed by nuclear-magnetic-resonance-based metabonomics.
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Title: Gas-phase structure of N,N-dimethylglycine.
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Title: Guanine and plasmid DNA binding of mono- and trinuclear fac-[Re(CO)3]+ complexes with amino acid ligands.
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Title: Crystal structure of DMGO provides a prototype for a new tetrahydrofolate-binding fold.
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Title: Di-mu-chloro-1:2kappa2Cl;3:4kappa2Cl-hexachloro-1kappa3Cl,4kappa3Cl-tetra-mu-dimethylglycine-2:3kappa8O:O'-tetracopper(II).
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Title: Crystal structure of heterotetrameric sarcosine oxidase from Corynebacterium sp. U-96.
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Title: A combined (1)H NMR and HPLC-MS-based metabonomic study of urine from obese (fa/fa) Zucker and normal Wistar-derived rats.
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Title: Amino acid promoted CuI-catalyzed C-N bond formation between aryl halides and amines or N-containing heterocycles.
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Title: Identification, cloning, and expression of Pseudomonas aeruginosa phosphorylcholine phosphatase gene.
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Title: Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.
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Title: Betaine and folate status as cooperative determinants of plasma homocysteine in humans.
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Title: The structure of the TrmE GTP-binding protein and its implications for tRNA modification.
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Title: Homocysteine, glycine betaine, and N,N-dimethylglycine in patients attending a lipid clinic.
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Title: Organic compatible solutes of halotolerant and halophilic microorganisms.
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Title: Betaine: a key modulator of one-carbon metabolism and homocysteine status.
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Title: Novel ruthenium complex K2[Ru(dmgly)Cl4].2H2O is toxic to C6 astrocytoma cell line, but not to primary rat astrocytes.
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Title: Chemical aspects of amine oxidation by flavoprotein enzymes.
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Title: A novel gamma-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1.
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Title: Dimethylglycine supplementation does not affect plasma homocysteine concentrations in pre-dialysis chronic renal failure patients.
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Title: Effects of intravenous betaine on methionine-loading-induced plasma homocysteine elevation in rats.
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Title: The trimethylammonium headgroup of choline is a major determinant for substrate binding and specificity in choline oxidase.
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Title: Over-expression in Escherichia coli, functional characterization and refolding of rat dimethylglycine dehydrogenase.
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Title: A nuclear-magnetic-resonance-based assay for betaine-homocysteine methyltransferase activity.
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Title: Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.
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Title: The osmoprotectants glycine and its methyl derivatives prevent the thermal inactivation of protective antigen of Bacillus anthracis.
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Title: Influence of hemodialysis membrane permeability on serum levels of advanced glycation end products (AGEs) and homocysteine metabolites.
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Title: Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.
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Title: A single arginine residue is required for the interaction of the electron transferring flavoprotein (ETF) with three of its dehydrogenase partners.
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Title: N,N-dimethyl glycine-promoted Ullmann coupling reaction of phenols and aryl halides.
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Title: CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models.
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Title: Determination of choline, betaine, and dimethylglycine in plasma by a high-throughput method based on normal-phase chromatography-tandem mass spectrometry.
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Title: The effect of short-term dimethylglycine treatment on oxygen consumption in cytochrome oxidase deficiency: a double-blind randomized crossover clinical trial.
Journal: The Journal of pediatrics 20030101
Title: Pharmacokinetics of oral betaine in healthy subjects and patients with homocystinuria.
Journal: British journal of clinical pharmacology 20030101
Title: Autism, an extreme challenge to integrative medicine. Part 2: medical management.
Journal: Alternative medicine review : a journal of clinical therapeutic 20021201
Title: Crystallization and preliminary X-ray study of recombinant betaine-homocysteine S-methyltransferase from rat liver.
Journal: Acta crystallographica. Section D, Biological crystallography 20020901
Title: Flavinylation of the precursor of mitochondrial dimethylglycine dehydrogenase by intact and solubilised mitochondria.
Journal: FEBS letters 20020703
Title: Functional characterization of betaine/proline transporters in betaine-accumulating mangrove.
Journal: The Journal of biological chemistry 20020524
Title: Mechanistic aspects of the covalent flavoprotein dimethylglycine oxidase of Arthrobacter globiformis studied by stopped-flow spectrophotometry.
Journal: Biochemistry 20020409
Title: Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure.
Journal: Kidney international 20020301
Title: Studies of the side chain cleavage of deramciclane in rats with radiolabelled compounds.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020301
Title: Random mutagenesis of the zinc-binding motif of betaine-homocysteine methyltransferase reveals that Gly 214 is essential.
Journal: Archives of biochemistry and biophysics 20020301
Title: Testosterone 17beta-N,N-dimethylglycinate hydrochloride: A prodrug with a potential for nasal delivery of testosterone.
Journal: Journal of pharmaceutical sciences 20020301
Title: Lysosomotropic N,N- dimethyl alpha-aminoacid N-alkyl esters and their quaternary ammonium salts as plasma membrane and mitochondrial ATPases inhibitors.
Journal: Cellular & molecular biology letters 20020101
Title: Decrease of elevated N,N-dimethylglycine and N-methylglycine in human immunodeficiency virus infection during short-term highly active antiretroviral therapy.
Journal: Metabolism: clinical and experimental 20011101
Title: Investigations into biochemical changes due to diurnal variation and estrus cycle in female rats using high-resolution (1)H NMR spectroscopy of urine and pattern recognition.
Journal: Analytical biochemistry 20010815
Title: Purification and kinetic properties of betaine-homocysteine methyltransferase from Aphanothece halophytica.
Journal: Current microbiology 20010801
Title: Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Journal: American journal of human genetics 20010701
Title: Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.
Journal: Kidney international 20010601
Title: Organization of the genes involved in dimethylglycine and sarcosine degradation in Arthrobacter spp.: implications for glycine betaine catabolism.
Journal: European journal of biochemistry 20010601
Title: Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency.
Journal: American journal of human genetics 20010401
Title: Conformation of cationic N,N-dimethylglycine in dimethylglycinium trifluoroacetate.
Journal: Acta crystallographica. Section C, Crystal structure communications 20010401
Title: Effectiveness of N,N-dimethylglycine in autism and pervasive developmental disorder.
Journal: Journal of child neurology 20010301
Title: Analysis of alcohols, as dimethylglycine esters, by electrospray ionization tandem mass spectrometry.
Journal: Journal of mass spectrometry : JMS 20010301
Title: Betaine:homocysteine methyltransferase from rat liver: purification and inhibition by a boronic acid substrate analog.
Journal: Archives of biochemistry and biophysics 19920101