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Home Other Building Blocks 1158838-45-9
1158838-45-9,MFCD16495816
Catalog No.:AA000GYG

1158838-45-9 | Tc-s 7010

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$199.00   $139.00
- +
10mg
≥98% (HPLC)
in stock  
$336.00   $235.00
- +
25mg
≥98% (HPLC)
in stock  
$686.00   $480.00
- +
50mg
≥98% (HPLC)
in stock  
$966.00   $677.00
- +
100mg
≥98% (HPLC)
in stock  
$1,736.00   $1,215.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA000GYG
Chemical Name:
Tc-s 7010
CAS Number:
1158838-45-9
Molecular Formula:
C31H31ClFN7O2
Molecular Weight:
588.0749
MDL Number:
MFCD16495816
SMILES:
CCN1CCN(CC1)C(=O)Cc1ccc(cc1)Nc1ncc(c(n1)Nc1ccc(cc1)C(=O)Nc1ccccc1Cl)F
Properties
Computed Properties
 
Complexity:
862  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
42  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
9  
XLogP3:
5.1  

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartAliagas-Martin,Ignacio;Burdick,Dan;Corson,Laura;Dotson,Jennafer;Drummond,Jason;Fields,Carter;Huang,OscarW.;Hunsaker,Thomas;Kleinheinz,Tracy;Krueger,Elaine;Liang,Jun;Moffat,John;Phillips,Gail;Pulk,Rebecca;Rawson,ThomasE.;Ultsch,Mark;Walker,Leslie;Wiesmann,Christian;Zhang,Birong;Zhu,Bing-Yan;Cochran,AndreaG.[JournalofMedicinalChemistry,2009,vol.52,#10,p.3300-3307]

Literature

Title: A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.

Journal: Journal of medicinal chemistry 20090528

Title: Aliagas-Martin I, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Huang OW, Hunsaker T, Kleinheinz T, Krueger E, Liang J, Moffat J, Phillips G, Pulk R, Rawson TE, Ultsch M, Walker L, Wiesmann C, Zhang B, Zhu BY, Cochran AG.A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.J Med Chem. 2009 May 28;52(10):3300-7.

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SDS
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Tags:1158838-45-9 Molecular Formula|1158838-45-9 MDL|1158838-45-9 SMILES|1158838-45-9 Tc-s 7010