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Home Bromides 116480-53-6
116480-53-6,MFCD09833477
Catalog No.:AA000CII

116480-53-6 | 5-Bromo-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole

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1g
97%
1 week  
$424.00   $297.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA000CII
Chemical Name:
5-Bromo-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole
CAS Number:
116480-53-6
Molecular Formula:
C14H15BrN2
Molecular Weight:
291.1863
MDL Number:
MFCD09833477
SMILES:
CN1CCC(=CC1)c1c[nH]c2c1cc(Br)cc2
Properties
Computed Properties
 
Complexity:
315  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
3  

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartShashikumar,NellisaraD.;Krishnamurthy,GangaNaika;RaoK,SundaraRaj;Shridhara,Kanakamajalu;Naik,HalehattiS.Bhojya;Nagarajan,Kuppuswamy[OrganicProcessResearchandDevelopment,2010,vol.14,#4,p.918-920]

[2]Slassi,Abdelmalik;Meng,CharlesQ.;Dyne,Kerry;Wang,Xin;Lee,DavidK.H.;Kamboj,Rajender;McCallum,KirkL.;Mazzocco,Lucy;Rakhit,Suman[MedicinalChemistryResearch,1999,vol.9,#9,p.668-674]

[3]CurrentPatentAssignee:ACIMMUNESA-US2011/280808,2011,A1Locationinpatent:Page/Pagecolumn45

[4]Sreenivasachary,Nampally;Kroth,Heiko;Benderitter,Pascal;Hamel,Anne;Varisco,Yvan;Hickman,DavidT.;Froestl,Wolfgang;Pfeifer,Andrea;Muhs,Andreas[BioorganicandMedicinalChemistryLetters,2017,vol.27,#6,p.1405-1411]

[5]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2007/98418,2007,A1Locationinpatent:Page/Pagecolumn84

[6]CurrentPatentAssignee:TAKEDAPHARMACEUTICALCOMPANYLIMITED-EP1173432,2007,B1Locationinpatent:Page/Pagecolumn13

[7]CurrentPatentAssignee:TAKEDAPHARMACEUTICALCOMPANYLIMITED-EP944595,2003,B1Locationinpatent:Page/Pagecolumn20

[8]Deskus,JeffreyA.;Epperson,JamesR.;Sloan,CharlesP.;Cipollina,JosephA.;Dextraze,Pierre;Qian-Cutrone,Jingfang;Gao,Qi;Ma,Baoqing;Beno,BrettR.;Mattson,GailK.;Molski,ThaddeusF.;Krause,RudolphG.;Taber,MatthewT.;Lodge,NicholasJ.;Mattson,RonaldJ.[BioorganicandMedicinalChemistryLetters,2007,vol.17,#11,p.3099-3104]

[9]CurrentPatentAssignee:ELILILLY&CO-EP978514,2000,A1

[10]CurrentPatentAssignee:ELILILLY&CO-US6358972,2002,B1

Literature

Title: Conformationally restricted homotryptamines 3. Indole tetrahydropyridines and cyclohexenylamines as selective serotonin reuptake inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20070601

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SDS
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Tags:116480-53-6 Molecular Formula|116480-53-6 MDL|116480-53-6 SMILES|116480-53-6 5-Bromo-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole