Title: Activation of melatonin receptor (MT1/2) promotes P-gp transporter in methamphetamine-induced toxicity on primary rat brain microvascular endothelial cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170601
Title: The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Journal: Toxicology 20170415
Title: Melatonin attenuates methamphetamine-induced neuroinflammation through the melatonin receptor in the SH-SY5Y cell line.
Journal: Neurotoxicology 20150901
Title: Melatonin Improves mitochondrial function by promoting MT1/SIRT1/PGC-1 alpha-dependent mitochondrial biogenesis in cadmium-induced hepatotoxicity in vitro.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20141101
Title: Synergistic effect of the L-tryptophan and kynurenic acid with dipyrone or paracetamol in mice.
Journal: Chemico-biological interactions 20130925
Title: Role of melatonin receptor MT(2) and quinone reductase II in the regulation of the redox status of 3T3-L1 preadipocytes in vitro.
Journal: Cell biology international 20130801
Title: Anxiolytic effects of the melatonin MT(2) receptor partial agonist UCM765: comparison with melatonin and diazepam.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20121203
Title: Melatonin suppresses doxorubicin-induced premature senescence of A549 lung cancer cells by ameliorating mitochondrial dysfunction.
Journal: Journal of pineal research 20121101
Title: Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1).
Journal: Journal of pineal research 20121101
Title: Evidence of the receptor-mediated influence of melatonin on pancreatic glucagon secretion via the Gαq protein-coupled and PI3K signaling pathways.
Journal: Journal of pineal research 20121101
Title: Melatonin down-regulates volume-sensitive chloride channels in fibroblasts.
Journal: Pflugers Archiv : European journal of physiology 20120901
Title: Short-term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light-dark cycle.
Journal: Journal of psychopharmacology (Oxford, England) 20120601
Title: Melatonin effects on Plasmodium life cycle: new avenues for therapeutic approach.
Journal: Recent patents on endocrine, metabolic & immune drug discovery 20120501
Title: Melatonin: neuritogenesis and neuroprotective effects in crustacean x-organ cells.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20120401
Title: Analyzing the responses of saccharin in context with melatonin receptors on the melanophores of the fish Labeo rohita (Ham.).
Journal: Journal of receptor and signal transduction research 20120401
Title: Melatonin inhibits glucocorticoid-dependent GR-TIF2 interaction in newborn hamster kidney (BHK) cells.
Journal: Molecular and cellular endocrinology 20120226
Title: Melatonin elicits protein kinase C-mediated calcium response in immortalized GT1-7 GnRH neurons.
Journal: Brain research 20120130
Title: Melatonin promotes differentiation of 3T3-L1 fibroblasts.
Journal: Journal of pineal research 20120101
Title: Melatonin membrane receptor type MT1 modulates cell-mediated immunity in the seasonally breeding tropical rodent Funambulus pennanti.
Journal: Neuroimmunomodulation 20120101
Title: Melatonin modulates the GABAergic response in cultured rat hippocampal neurons.
Journal: Journal of pharmacological sciences 20120101
Title: Effects of melatonin and its receptor antagonist on retinal pigment epithelial cells against hydrogen peroxide damage.
Journal: Molecular vision 20120101
Title: The effects of light regimes and hormones on corneal growth in vivo and in organ culture.
Journal: Journal of anatomy 20111201
Title: The interaction of melatonin and agmatine on pentylenetetrazole-induced seizure threshold in mice.
Journal: Epilepsy & behavior : E&B 20111001
Title: Study of the effects of the casein derived bitter tastant on the melanophores in milieu with the melatonin receptors.
Journal: Journal of receptor and signal transduction research 20111001
Title: Rat pial microvascular responses to melatonin during bilateral common carotid artery occlusion and reperfusion.
Journal: Journal of pineal research 20110801
Title: Melatonin elevates intracellular free calcium in human platelets by inositol 1,4,5-trisphosphate independent mechanism.
Journal: FEBS letters 20110721
Title: Design of novel melatonin analogs for the reduction of intraocular pressure in normotensive rabbits.
Journal: The Journal of pharmacology and experimental therapeutics 20110601
Title: 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT₂-selective agonists.
Journal: Journal of medicinal chemistry 20110512
Title: Melatonin-induced protein synthesis in the rat parotid gland.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201
Title: Apelin stimulation of duodenal bicarbonate secretion: feeding-dependent and mediated via apelin-induced release of enteric cholecystokinin.
Journal: Acta physiologica (Oxford, England) 20110101
Title: Expression of functional melatonin MT(1) receptors in equine luteal cells: in vitro effects of melatonin on progesterone secretion.
Journal: Reproduction, fertility, and development 20110101
Title: Melatonin inhibits adipogenesis and enhances osteogenesis of human mesenchymal stem cells by suppressing PPARγ expression and enhancing Runx2 expression.
Journal: Journal of pineal research 20101101
Title: Electrophysiological effects of melatonin on mouse Per1 and non-Per1 suprachiasmatic nuclei neurones in vitro.
Journal: Journal of neuroendocrinology 20101101
Title: Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1).
Journal: Journal of pineal research 20101001
Title: Melatonin increases proliferation of cultured neural stem cells obtained from adult mouse subventricular zone.
Journal: Journal of pineal research 20101001
Title: Signal transduction of receptor-mediated antiproliferative action of melatonin on human prostate epithelial cells involves dual activation of Gα(s) and Gα(q) proteins.
Journal: Journal of pineal research 20101001
Title: Anti-inflammatory action of cholecystokinin and melatonin in the rat parotid gland.
Journal: Oral diseases 20101001
Title: Synergistic neuroprotective effect of combined low concentrations of galantamine and melatonin against oxidative stress in SH-SY5Y neuroblastoma cells.
Journal: Journal of pineal research 20100901
Title: Abnormal proliferation and differentiation of osteoblasts from girls with adolescent idiopathic scoliosis to melatonin.
Journal: Journal of pineal research 20100801
Title: Melatonin modifies the rhythm of protein synthesis.
Journal: Bulletin of experimental biology and medicine 20100701
Title: Antinociceptive effects of melatonin in a rat model of post-inflammatory visceral hyperalgesia: a centrally mediated process.
Journal: Pain 20100601
Title: Melatonin and the time window for the expression of the alpha8 nicotinic acetylcholine receptor in the membrane of chick retinal cells in culture.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20100501
Title: The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors.
Journal: Journal of pineal research 20100301
Title: Malaria: therapeutic implications of melatonin.
Journal: Journal of pineal research 20100101
Title: Inhibition of breast cancer cell invasion by melatonin is mediated through regulation of the p38 mitogen-activated protein kinase signaling pathway.
Journal: Breast cancer research : BCR 20100101
Title: The end of a myth: cloning and characterization of the ovine melatonin MT(2) receptor.
Journal: British journal of pharmacology 20091101
Title: An unexpected effect of 5-MCA-NAT in chick retinal development.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20091001
Title: Melatonin modulates cell survival of new neurons in the hippocampus of adult mice.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090801
Title: Neuroprotection by melatonin on astrocytoma cell death.
Journal: Annals of the New York Academy of Sciences 20090801
Title: Melatonin protects against experimental reflux esophagitis.
Journal: Journal of pineal research 20090301
Title: Antagonistic effect of luzindole in mice treated with melatonin during the infection with the venezuelan equine encephalomyelitis virus.
Journal: Neurochemical research 20090201
Title: A novel interplay between membrane and nuclear melatonin receptors in human lymphocytes: significance in IL-2 production.
Journal: Cellular and molecular life sciences : CMLS 20090201
Title: Luzindole but not 4-phenyl-2- propionamidotetralin (4P-PDOT) diminishes the inhibitory effect of melatonin on murine Colon 38 cancer growth in vitro.
Journal: Neuro endocrinology letters 20090101
Title: Diurnal variation in phagocytic activity of splenic phagocytes in freshwater teleost Channa punctatus: melatonin and its signaling mechanism.
Journal: The Journal of endocrinology 20081201
Title: Melatonin-evoked in vivo secretion of protein and amylase from the parotid gland of the anaesthetised rat.
Journal: Journal of pineal research 20081101
Title: Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance.
Journal: Journal of pineal research 20081101
Title: Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions.
Journal: Journal of pineal research 20081101
Title: Melatonin-enhanced hyperactivation of hamster sperm.
Journal: Reproduction (Cambridge, England) 20081101
Title: Melatonin reverses the expression of morphine-induced conditioned place preference through its receptors within central nervous system in mice.
Journal: European journal of pharmacology 20081010
Title: Melatonin receptor antagonist luzindole is a powerful radical scavenger in vitro.
Journal: Journal of pineal research 20081001
Title: Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells.
Journal: Journal of pineal research 20081001
Title: Selective activation of melatonin receptors with ramelteon improves liver function and hepatic perfusion after hemorrhagic shock in rat.
Journal: Critical care medicine 20081001
Title: Melatonin receptor agonist ramelteon activates the extracellular signal-regulated kinase 1/2 in mouse cerebellar granule cells.
Journal: Neuroscience 20080909
Title: Influence of serotonin on the action of melatonin in MIH-induced meiotic resumption in the oocytes of carp Catla catla.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080701
Title: Agomelatine, a melatonin receptor agonist with 5-HT(2C) receptor antagonist properties, protects the developing murine white matter against excitotoxicity.
Journal: European journal of pharmacology 20080624
Title: MT1 melatonin receptor internalization underlies melatonin-induced morphologic changes in Chinese hamster ovary cells and these processes are dependent on Gi proteins, MEK 1/2 and microtubule modulation.
Journal: Journal of pineal research 20080401
Title: Melatonin antagonizes the intrinsic pathway of apoptosis via mitochondrial targeting of Bcl-2.
Journal: Journal of pineal research 20080401
Title: 7Alpha-hydroxypregnenolone mediates melatonin action underlying diurnal locomotor rhythms.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080227
Title: Melatonin inhibitory effect on cAMP accumulation in the chick retina development.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20080101
Title: Design, synthesis, and melatoninergic activity of new azido- and isothiocyanato-substituted indoles.
Journal: Journal of medicinal chemistry 20071213
Title: Effect of luzindole and other melatonin receptor antagonists on iron- and lipopolysaccharide-induced lipid peroxidation in vitro.
Journal: Annals of the New York Academy of Sciences 20071201
Title: Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.
Journal: Journal of pineal research 20071001
Title: Design and synthesis of new N1 and C3-substituted 4-fluoroindolic melatoninergics.
Journal: Current drug discovery technologies 20071001
Title: Melatonin antagonizes apoptosis via receptor interaction in U937 monocytic cells.
Journal: Journal of pineal research 20070901
Title: Melatonin attenuates the development of antinociceptive tolerance to delta-, but not to mu-opioid receptor agonist in mice.
Journal: Behavioural brain research 20070822
Title: Design, synthesis and melatoninergic activity of new unsubstituted and beta,beta'-difunctionalised 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-6-alkanamides.
Journal: European journal of medicinal chemistry 20070701
Title: [The effect of melatonin on the regulation of collagen accumulation and matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 mRNA and protein in a murine model of chronic asthma].
Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20070701
Title: Hypothermic effects of hops are antagonized with the competitive melatonin receptor antagonist luzindole in mice.
Journal: The Journal of pharmacy and pharmacology 20070401
Title: Melatonin potentiates tear secretion induced by diadenosine tetraphosphate in the rabbit.
Journal: European journal of pharmacology 20061215
Title: Melatonin affects the immobility time of rats in the forced swim test: the role of serotonin neurotransmission.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20061001
Title: Beneficial effects of melatonin in protecting against cyclosporine A-induced cardiotoxicity are receptor mediated.
Journal: Journal of pineal research 20061001
Title: Melatonin and lipid uptake by murine fibroblasts: clinical implications.
Journal: Neuro endocrinology letters 20061001
Title: Melatonin synthesized by Jurkat human leukemic T cell line is implicated in IL-2 production.
Journal: Journal of cellular physiology 20060101
Title: Short- and long-term effects of melatonin on myocardial post-ischemic recovery.
Journal: Journal of pineal research 20060101
Title: Modulation by melatonin of glutamatergic synaptic transmission in the carp retina.
Journal: The Journal of physiology 20051215
Title: Melatonin inhibits hippocampal long-term potentiation.
Journal: The European journal of neuroscience 20051101
Title: The antidepressant-like effect of the melatonin receptor ligand luzindole in mice during forced swimming requires expression of MT2 but not MT1 melatonin receptors.
Journal: Journal of pineal research 20050901
Title: Molecular tools to study melatonin pathways and actions.
Journal: Trends in pharmacological sciences 20050801
Title: Melatonin enhances leptin expression by rat adipocytes in the presence of insulin.
Journal: American journal of physiology. Endocrinology and metabolism 20050401
Title: Melatonin enhances the hypoxic response of rat carotid body chemoreceptor.
Journal: Journal of pineal research 20050401
Title: Melatonin-induced modulation of glucose metabolism in primary cultures of rabbit kidney-cortex tubules.
Journal: Journal of pineal research 20050401
Title: Hippocampal melatonin receptors modulate seizure threshold.
Journal: Epilepsia 20050401
Title: Influence of melatonin on the development of functional nicotinic acetylcholine receptors in cultured chick retinal cells.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20050401
Title: Direct effect of melatonin on Syrian hamster testes: melatonin subtype 1a receptors, inhibition of androgen production, and interaction with the local corticotropin-releasing hormone system.
Journal: Endocrinology 20050301
Title: Human lymphocyte-synthesized melatonin is involved in the regulation of the interleukin-2/interleukin-2 receptor system.
Journal: The Journal of clinical endocrinology and metabolism 20050201
Title: Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes.
Journal: Journal of gastroenterology and hepatology 20050201
Title: Intracellular second messengers involved in melatonin signal transduction in chicken splenocytes in vitro.
Journal: Journal of pineal research 20041001
Title: In vivo activation of insulin receptor tyrosine kinase by melatonin in the rat hypothalamus.
Journal: Journal of neurochemistry 20040801
Title: Diurnal changes of tonic nociceptive responses in mice: evidence for a proalgesic role of melatonin.
Journal: Pain 20040701
Title: Melatonin and its precursor, L-tryptophan: influence on pancreatic amylase secretion in vivo and in vitro.
Journal: Journal of pineal research 20040401
Title: Characterization of melatonin binding sites in the brain and retina of the frog Rana perezi.
Journal: General and comparative endocrinology 20040201
Title: Melatonin attenuates rat carotid chemoreceptor response to hypercapnic acidosis.
Journal: Journal of pineal research 20040101
Title: Effect of melatonin on the oxidative stress in N1E-115 cells is not mediated by mt1 receptors.
Journal: Journal of physiology and biochemistry 20031201
Title: Diurnal actions of melatonin on epileptic activity in hippocampal slices of rats.
Journal: Life sciences 20031003
Title: Melatonin binding sites in estrogen receptor-positive cells derived from human endometrial cancer.
Journal: Journal of pineal research 20030901
Title: Melatonin enhances lymphocyte proliferation and decreases the release of pituitary pro-opiomelanocortin-derived peptides in surgically traumatized rats.
Journal: Neuroscience letters 20030605
Title: New selective ligands of human cloned melatonin MT1 and MT2 receptors.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030601
Title: Melatonin biological activity and binding sites in human melanoma cells.
Journal: Journal of pineal research 20030501
Title: Melatonin in the duodenal lumen is a potent stimulant of mucosal bicarbonate secretion.
Journal: Journal of pineal research 20030501
Title: Luzindole, a melatonin receptor antagonist, inhibits the transient outward K+ current in rat cerebellar granule cells.
Journal: Brain research 20030425
Title: Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
Journal: Journal of medicinal chemistry 20030410
Title: Short-term exposure to melatonin differentially affects the functional sensitivity and trafficking of the hMT1 and hMT2 melatonin receptors.
Journal: The Journal of pharmacology and experimental therapeutics 20030301
Title: Melatonin modulates the light-induced sympathoexcitation and vagal suppression with participation of the suprachiasmatic nucleus in mice.
Journal: The Journal of physiology 20030215
Title: Role of endogenous melatonin and its MT2 receptor in the modulation of caerulein-induced pancreatitis in the rat.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20021201
Title: Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.
Journal: Journal of pineal research 20020901
Title: Small doses of melatonin increase intestinal motility in rats.
Journal: Digestive diseases and sciences 20020901
Title: Influence of melatonin on chicken lymphocytes in vitro: involvement of membrane receptors.
Journal: Neuro endocrinology letters 20020401
Title: Role of prostaglandins, nitric oxide, sensory nerves and gastrin in acceleration of ulcer healing by melatonin and its precursor, L-tryptophan.
Journal: Journal of pineal research 20020401
Title: Receptor-mediated modulation of avian caecal muscle contraction by melatonin: role of tyrosine protein kinase.
Journal: Journal of pineal research 20020401
Title: Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge.
Journal: Annals of neurology 20020101
Title: Melatonin receptors in rat hippocampus: molecular and functional investigations.
Journal: Hippocampus 20020101
Title: Melatonin-induced suppression of PC12 cell growth is mediated by its Gi coupled transmembrane receptors.
Journal: Brain research 20011116
Title: Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation.
Journal: European journal of pharmacology 20011102
Title: Cyclical regulation of GnRH gene expression in GT1-7 GnRH-secreting neurons by melatonin.
Journal: Endocrinology 20011101
Title: Effects of microinjection of melatonin and its receptor antagonists into anterior hypothalamic area on blood pressure and heart rate in rats.
Journal: Acta pharmacologica Sinica 20011101
Title: Melatonin receptor subtype MT2 (Mel 1b) and not mt1 (Mel 1a) is associated with melatonin-induced enhancement of cell-mediated and humoral immunity.
Journal: Neuroendocrinology 20010901
Title: Peripheral melatonin mediates neural stimulation of duodenal mucosal bicarbonate secretion.
Journal: The Journal of clinical investigation 20010815
Title: Melatonin increases pial artery tone and decreases the lower limit of cerebral blood flow autoregulation.
Journal: Fundamental & clinical pharmacology 20010801
Title: Melatonin reduces anxiety induced by lipopolysaccharide in the rat.
Journal: Neuroscience letters 20010706
Title: Reversal of reserpine-induced vacuous chewing movements in rats by melatonin: involvement of peripheral benzodiazepine receptors.
Journal: Brain research 20010615
Title: Melatonin enhancement of splenocyte proliferation is attenuated by luzindole, a melatonin receptor antagonist.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010501
Title: Serine residues 110 and 114 are required for agonist binding but not antagonist binding to the melatonin MT(1) receptor.
Journal: Biochemical and biophysical research communications 20010420
Title: Food intake inhibition by melatonin in goldfish (Carassius auratus).
Journal: Physiology & behavior 20010401
Title: Involvement of melatonin MT(3) receptors in the regulation of intraocular pressure in rabbits.
Journal: European journal of pharmacology 20010330
Title: Disruption of mitochondrial respiration by melatonin in MCF-7 cells.
Journal: Toxicology and applied pharmacology 20010315
Title: The modulation of neuronal activity by melatonin: in vitro studies on mouse hippocampal slices.
Journal: Journal of pineal research 20010301
Title: Melatonin inhibits Arg-vasopressin release via MT(2) receptor in the suprachiasmatic nucleus-slice culture of rats.
Journal: Brain research 20010119
Title: Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock.
Journal: American journal of physiology. Cell physiology 20010101
Title: Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1-a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles.
Journal: Journal of medicinal chemistry 20000323
Title: Pharmacological characterization of human recombinant melatonin mt(1) and MT(2) receptors.
Journal: British journal of pharmacology 20000301
Title: Design of subtype selective melatonin receptor agonists and antagonists.
Journal: Reproduction, nutrition, development 19990101
Title: Comparison of the structure-activity relationships of melatonin receptor agonists and antagonists: lengthening the N-acyl side-chain has differing effects on potency on Xenopus melanophores.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 19981101
Title: Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19980901
Title: Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 19970301
Title: Luzindole (N-0774): a novel melatonin receptor antagonist.
Journal: The Journal of pharmacology and experimental therapeutics 19880901
Title: Dubocovich ML, et al. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355(3):365-75.
Title: Constantinescu CS, et al. Luzindole, a melatonin receptor antagonist, suppresses experimental autoimmune encephalomyelitis. Pathobiology. 1997;65(4):190-4.
Title: Dubocovich ML Antidepressant-like activity of the melatonin receptor antagonist, luzindole (N-0774), in the mouse behavioral despair test. Eur J Pharmacol. 1990 Jul 3;182(2):313-25.
