Home Amines 118454-24-3
118454-24-3,MFCD11046302
Catalog No.:AA0095T1

118454-24-3 | tert-Butyl 7-amino-4,5-dihydro-1H-benzo[d]azepine-3(2H)-carboxylate

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100mg
95%
in stock  
$205.00   $144.00
- +
250mg
95%
in stock  
$342.00   $240.00
- +
500mg
95%
in stock  
$488.00   $342.00
- +
1g
95%
in stock  
$730.00   $511.00
- +
5g
95%
in stock  
$2,326.00   $1,628.00
- +
10g
95%
in stock  
$3,825.00   $2,678.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0095T1
Chemical Name:
tert-Butyl 7-amino-4,5-dihydro-1H-benzo[d]azepine-3(2H)-carboxylate
CAS Number:
118454-24-3
Molecular Formula:
C15H22N2O2
Molecular Weight:
262.3474
MDL Number:
MFCD11046302
SMILES:
Nc1ccc2c(c1)CCN(CC2)C(=O)OC(C)(C)C
Properties
Computed Properties
 
Complexity:
325  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
2.4  

Downstream Synthesis Route

[1]Garzya,Vincenzo;Forbes,IanT.;Gribble,AndrewD.;Hadley,MikeS.;Lightfoot,AndrewP.;Payne,AndrewH.;Smith,AlexanderB.;Douglas,SaraE.;Cooper,DavidG.;Stansfield,IanG.;Meeson,Malcom;Dodds,EmmaE.;Jones,DeclanN.C.;Wood,Martyn;Reavill,Charlie;Scorer,CarolA.;Worby,Angela;Riley,Graham;Eddershaw,Peter;Ioannou,Chris;Donati,Daniele;Hagan,JimJ.;Ratti,EmiliangeloA.[BioorganicandMedicinalChemistryLetters,2007,vol.17,#2,p.400-405]

118454-24-3    131880-55-2   
C26H34N2O5S 

[1]Locationinpatent:schemeortableBailey,JamesM.;Scott,JackieS.;Basilla,JonathanB.;Bolton,VictoriaJ.;Boyfield,Izzy;Evans,DavidG.;Fleury,Etienne;Heightman,TomD.;Jarvie,EmmaM.;Lawless,Kirk;Matthews,KimL.;McKay,Fiona;Mok,Hindy;Muir,Alison;Orlek,BarryS.;Sanger,GarethJ.;Stemp,Geoffrey;Stevens,AlexanderJ.;Thompson,Mervyn;Ward,John;Vaidya,Kalindi;Westaway,SusanM.[BioorganicandMedicinalChemistryLetters,2009,vol.19,#22,p.6452-6458]

118454-24-3    42413-03-6   
C22H27ClN2O4S 

[1]BioorganicandMedicinalChemistryLetters,2009,vol.19,p.6452-6458

118454-24-3    151858-64-9   
C24H27N3O4S2 

[1]Locationinpatent:schemeortableBailey,JamesM.;Scott,JackieS.;Basilla,JonathanB.;Bolton,VictoriaJ.;Boyfield,Izzy;Evans,DavidG.;Fleury,Etienne;Heightman,TomD.;Jarvie,EmmaM.;Lawless,Kirk;Matthews,KimL.;McKay,Fiona;Mok,Hindy;Muir,Alison;Orlek,BarryS.;Sanger,GarethJ.;Stemp,Geoffrey;Stevens,AlexanderJ.;Thompson,Mervyn;Ward,John;Vaidya,Kalindi;Westaway,SusanM.[BioorganicandMedicinalChemistryLetters,2009,vol.19,#22,p.6452-6458]

[1]Urbanek,RebeccaA.;Xiong,Hui;Wu,Ye;Blackwell,William;Steelman,Gary;Rosamond,Jim;Wesolowski,StevenS.;Campbell,JamesB.;Zhang,Minli;Brockel,Becky;Widzowski,DanielV.[BioorganicandMedicinalChemistryLetters,2013,vol.23,#2,p.543-547]

[2]Urbanek,RebeccaA.;Xiong,Hui;Wu,Ye;Blackwell,William;Steelman,Gary;Rosamond,Jim;Wesolowski,StevenS.;Campbell,JamesB.;Zhang,Minli;Brockel,Becky;Widzowski,DanielV.[BioorganicandMedicinalChemistryLetters,2013,vol.23,#2,p.543-547]

[3]Johnson,ChristopherN.;Berdini,Valerio;Beke,Lijs;Bonnet,Pascal;Brehmer,Dirk;Coyle,JosephE.;Day,PhillipJ.;Frederickson,Martyn;Freyne,EddyJ.E.;Gilissen,RonA.H.J.;Hamlett,ChristopherC.F.;Howard,Steven;Meerpoel,Lieven;McMenamin,Rachel;Patel,Sahil;Rees,DavidC.;Sharff,Andrew;Sommen,Franois;Wu,Tongfei;Linders,JoannesT.M.[ACSMedicinalChemistryLetters,2015,vol.6,#1,p.25-30]

[4]Xiong,Hui;Wu,Ye;Lehr,ScottG.;Blackwell,William;Steelman,Gary;Hulsizer,Jim;Urbanek,RebeccaA.[TetrahedronLetters,2012,vol.53,#44,p.5833-5836,4]

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SDS
Tags:118454-24-3 Molecular Formula|118454-24-3 MDL|118454-24-3 SMILES|118454-24-3 tert-Butyl 7-amino-4,5-dihydro-1H-benzo[d]azepine-3(2H)-carboxylate