Home Other Building Blocks 4424-20-8
4424-20-8,MFCD04012620
Catalog No.:AA00726J

4424-20-8 | 2,3,4,5-Tetrahydro-1h-benzo[d]azepine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$39.00   $28.00
- +
250mg
95%
in stock  
$66.00   $47.00
- +
1g
95%
in stock  
$128.00   $90.00
- +
5g
95%
in stock  
$581.00   $407.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00726J
Chemical Name:
2,3,4,5-Tetrahydro-1h-benzo[d]azepine
CAS Number:
4424-20-8
Molecular Formula:
C10H13N
Molecular Weight:
147.2169
MDL Number:
MFCD04012620
SMILES:
N1CCc2c(CC1)cccc2
Properties
Computed Properties
 
Complexity:
108  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.8  

Literature

Title: Melanin-concentrating hormone receptor 1 antagonists: synthesis, structure-activity relationship, docking studies, and biological evaluation of 2,3,4,5-tetrahydro-1H-3-benzazepine derivatives.

Journal: Bioorganic & medicinal chemistry 20111101

Title: Novel 2,3,4,5-tetrahydro-benzo[d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models.

Journal: Bioorganic & medicinal chemistry letters 20110101

Title: SAR studies of capsazepinoid bronchodilators. Part 1: The importance of the catechol moiety and aspects of the B-ring structure.

Journal: Bioorganic & medicinal chemistry 20080301

Title: Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity.

Journal: Journal of medicinal chemistry 20080124

Title: Design and synthesis of trans-3-(2-(4-((3-(3-(5-methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine (SB-414796): a potent and selective dopamine D3 receptor antagonist.

Journal: Journal of medicinal chemistry 20031106

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SDS
Tags:4424-20-8 Molecular Formula|4424-20-8 MDL|4424-20-8 SMILES|4424-20-8 2,3,4,5-Tetrahydro-1h-benzo[d]azepine