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118458-54-1,MFCD03452662
Catalog No.:AA00769Y

118458-54-1 | Arcyriaflavin A

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1mg
≥95%
in stock  
$82.00   $57.00
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5mg
≥95%
in stock  
$199.00   $139.00
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10mg
≥95%
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$315.00   $220.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00769Y
Chemical Name:
Arcyriaflavin A
CAS Number:
118458-54-1
Molecular Formula:
C20H11N3O2
Molecular Weight:
325.3202
MDL Number:
MFCD03452662
SMILES:
O=c1[nH]c(=O)c2c1c1c3ccccc3[nH]c1c1c2c2ccccc2[nH]1
Properties
Computed Properties
 
Complexity:
570  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
3  
XLogP3:
3.6  

Literature

Title: Characterization and functional modification of StaC and RebC, which are involved in the pyrrole oxidation of indolocarbazole biosynthesis.

Journal: Bioscience, biotechnology, and biochemistry 20110101

Title: Identification of bisindolylmaleimides and indolocarbazoles as inhibitors of HCV replication by tube-capture-RT-PCR.

Journal: Antiviral research 20090801

Title: Theoretical study of photophysical properties of bisindolylmaleimide derivatives.

Journal: The journal of physical chemistry. A 20090723

Title: Generation of potent and selective kinase inhibitors by combinatorial biosynthesis of glycosylated indolocarbazoles.

Journal: Chemical communications (Cambridge, England) 20090721

Title: Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20070925

Title: Aryl[a]pyrrolo[3,4-c]carbazoles as selective cyclin D1-CDK4 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20031103

Title: Synthesis, structure-activity relationship, and biological studies of indolocarbazoles as potent cyclin D1-CDK4 inhibitors.

Journal: Journal of medicinal chemistry 20030522

Title: Synthesis of N-alkyl substituted indolocarbazoles as potent inhibitors of human cytomegalovirus replication.

Journal: Bioorganic & medicinal chemistry letters 20010806

Title: Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication.

Journal: Bioorganic & medicinal chemistry 19990601

Title: Structure-activity relationships in a series of substituted indolocarbazoles: topoisomerase I and protein kinase C inhibition and antitumoral and antimicrobial properties.

Journal: Journal of medicinal chemistry 19961025

Title: P A Horton, et al. Staurosporine aglycone (K252-c) and arcyriaflavin A from the marine ascidian, Eudistoma sp. Experientia. 1994 Sep 15;50(9):843-5.

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