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118506-26-6,MFCD00237186
Catalog No.:AA008RK3

118506-26-6 | MYELIN BASIC PROTEIN (87-99) (HUMAN, BOVINE, RAT)

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Purity
Availability
Price(USD)
Quantity
  
1mg
2 weeks  
$358.00   $250.00
- +
2mg
2 weeks  
$509.00   $357.00
- +
5mg
2 weeks  
$786.00   $550.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008RK3
Chemical Name:
MYELIN BASIC PROTEIN (87-99) (HUMAN, BOVINE, RAT)
CAS Number:
118506-26-6
Molecular Formula:
C74H114N20O17
Molecular Weight:
1555.8208
MDL Number:
MFCD00237186
SMILES:
NCCCCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)O)C(O)C)CCCN=C(N)N)C(O)C)C(C)C)C(CC)C)CC(=O)N)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(C(C)C)N)Cc1[nH]cnc1)Cc1ccccc1)Cc1ccccc1
Properties
Computed Properties
 
Complexity:
3170  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
16  
Heavy Atom Count:
111  
Hydrogen Bond Acceptor Count:
21  
Hydrogen Bond Donor Count:
19  
Rotatable Bond Count:
45  
XLogP3:
-3.4  

Literature

Title: Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease.

Journal: Journal of medicinal chemistry 20081225

Title: The therapeutic window after spinal cord injury can accommodate T cell-based vaccination and methylprednisolone in rats.

Journal: The European journal of neuroscience 20040601

Title: R E Jones, et al. The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats. J Neuroimmunol. 1992 Apr;37(3):203-12.

Title: George Deraos, et al. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. J Med Chem. 2008 Dec 25;51(24):7834-42.

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SDS
Tags:118506-26-6 Molecular Formula|118506-26-6 MDL|118506-26-6 SMILES|118506-26-6 MYELIN BASIC PROTEIN (87-99) (HUMAN, BOVINE, RAT)