+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
1193383-09-3,MFCD25541711
Catalog No.:AA000IJD

1193383-09-3 | JNJ-42041935

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$20.00   $14.00
- +
5mg
98+%
in stock  
$46.00   $32.00
- +
10mg
98+%
in stock  
$66.00   $46.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA000IJD
Chemical Name:
JNJ-42041935
CAS Number:
1193383-09-3
Molecular Formula:
C12H6ClF3N4O3
Molecular Weight:
346.6492
MDL Number:
MFCD25541711
SMILES:
OC(=O)c1cnn(c1)c1[nH]c2c(n1)cc(c(c2)Cl)OC(F)(F)F
Properties
Computed Properties
 
Complexity:
469  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.1  

Downstream Synthesis Route

[1]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2009/134750,2009,A1Locationinpatent:Page/Pagecolumn134-135

[1]Patent:WO2009/134750,2009,A1

[1]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2009/134750,2009,A1

[1]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2009/134750,2009,A1

Literature

Title: The stabilization of hypoxia inducible factor modulates differentiation status and inhibits the proliferation of mouse embryonic stem cells.

Journal: Chemico-biological interactions 20160125

Title: Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor.

Journal: Molecular pharmacology 20110601

Title: Barrett TD, et al. Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor. Mol Pharmacol. 2011

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 1193383-09-3
Building Blocks
More >
Historical Records
1062174-44-0

1062174-44-0

 1713160-57-6

1713160-57-6

 207742-76-5

207742-76-5

 1020054-41-4

1020054-41-4
Tags:1193383-09-3 Molecular Formula|1193383-09-3 MDL|1193383-09-3 SMILES|1193383-09-3 JNJ-42041935
Catalog No.: AA000IJD
1193383-09-3,MFCD25541711
1193383-09-3 | JNJ-42041935
Pack Size： 1mg
Purity： 98+%
in stock
$20.00 $14.00
Pack Size： 5mg
Purity： 98+%
in stock
$46.00 $32.00
Pack Size： 10mg
Purity： 98+%
in stock
$66.00 $46.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA000IJD
Chemical Name: JNJ-42041935
CAS Number: 1193383-09-3
Molecular Formula: C12H6ClF3N4O3
Molecular Weight: 346.6492
MDL Number: MFCD25541711
SMILES: OC(=O)c1cnn(c1)c1[nH]c2c(n1)cc(c(c2)Cl)OC(F)(F)F
Properties
Complexity: 469  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 23  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.1  
Downstream Synthesis Route
1193384-77-8    1193383-09-3 

[1]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2009/134750,2009,A1Locationinpatent:Page/Pagecolumn134-135

914637-23-3    1193383-09-3 

[1]Patent:WO2009/134750,2009,A1

156425-08-0    1193383-09-3 

[1]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2009/134750,2009,A1

1193384-75-6    1193383-09-3 

[1]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2009/134750,2009,A1

Literature fold

Title: The stabilization of hypoxia inducible factor modulates differentiation status and inhibits the proliferation of mouse embryonic stem cells.

Journal: Chemico-biological interactions20160125

Title: Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor.

Journal: Molecular pharmacology20110601

Title: Barrett TD, et al. Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor. Mol Pharmacol. 2011

Related Products of of 1193383-09-3
Building Blocks More >
1195251-01-4
1195251-01-4
4-Chloro-3-fluoro-2-methylpyridine
AA000IUQ | MFCD16610395
1227575-47-4
1227575-47-4
Methyl 5-fluoropyrimidine-2-carboxylate
AA000J85 | MFCD16611615
1228376-68-8
1228376-68-8
4-Amino-2-chloro-5-fluorobenzonitrile
AA000JH5 | MFCD11110982
1229208-44-9
1229208-44-9
GS-9973
AA000JOP | MFCD28099806
123184-19-0
123184-19-0
2-Bromo-1-(2,6-dimethoxyphenyl)ethanone
AA000K1W | MFCD03425183
1233526-47-0
1233526-47-0
1-(Cyclobutylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-pyrazole
AA000KCN | MFCD18383241
123530-67-6
123530-67-6
3-Benzothiazol-2-yl-acrylic acid
AA000KNB | MFCD00498593
123760-47-4
123760-47-4
(Methyl(2-naphthylsulfonyl)amino)acetic acid
AA000KZ4 | MFCD01249749
62238-80-6
62238-80-6
2-Propen-1-amine, N-2-propen-1-yl-
AA01X3GP | MFCD00008642
124223-99-0
124223-99-0
2H-1-Benzopyran-2-one, 7-[[2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]oxy]-4-methyl-
AA000LMD | MFCD00270047
Historical Records
1062174-44-0
1062174-44-0
1713160-57-6
1713160-57-6
207742-76-5
207742-76-5
1020054-41-4
1020054-41-4
Submit
© 2017 AA BLOCKS, INC. All rights reserved.