Home Amines 127984-74-1
127984-74-1,MFCD00873576
Catalog No.:AA009EY4

127984-74-1 | 10-(4-aminobutyl)-19-[(2-amino-3-naphthalen-2-yl-propanoyl)amino]-N-(1 -carbamoyl-2-hydroxy-propyl)-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol -3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14, 17-pentazacycloicosane-4-carboxamide

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1mg
≥98%
in stock  
$46.00   $32.00
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5mg
95%
in stock  
$154.00   $108.00
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10mg
95%
in stock  
$288.00   $202.00
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25mg
95%
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$574.00   $402.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009EY4
Chemical Name:
10-(4-aminobutyl)-19-[(2-amino-3-naphthalen-2-yl-propanoyl)amino]-N-(1 -carbamoyl-2-hydroxy-propyl)-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol -3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14, 17-pentazacycloicosane-4-carboxamide
CAS Number:
127984-74-1
Molecular Formula:
C54H69N11O10S2
Molecular Weight:
1096.3234
MDL Number:
MFCD00873576
SMILES:
NCCCCC1NC(=O)C(NC(=O)C(Cc2ccc(cc2)O)NC(=O)C(CSSCC(NC(=O)C(NC1=O)C(C)C)C(=O)NC(C(=O)N)C(O)C)NC(=O)C(Cc1ccc2c(c1)cccc2)N)Cc1c[nH]c2c1cccc2
Properties
Computed Properties
 
Complexity:
2000  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
77  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
13  
Rotatable Bond Count:
17  
Undefined Atom Stereocenter Count:
9  
XLogP3:
2.5  

Literature

Title: Telotristat Ethyl, a Tryptophan Hydroxylase Inhibitor for the Treatment of Carcinoid Syndrome.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20170101

Title: Role of Somatostatin Analogues in the Treatment of Neuroendocrine Tumors.

Journal: Hematology/oncology clinics of North America 20160201

Title: Investigational drugs targeting somatostatin receptors for treatment of acromegaly and neuroendocrine tumors.

Journal: Expert opinion on investigational drugs 20141201

Title: Lanreotide autogel in acromegaly - a decade on.

Journal: Expert opinion on pharmacotherapy 20141201

Title: Lanreotide Autogel 90 mg and lymphorrhea prevention after axillary node dissection in breast cancer: a phase III double blind, randomized, placebo-controlled trial.

Journal: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20121001

Title: The use of lanreotide in the management of lymphorrhea after an aortic valve replacement.

Journal: Interactive cardiovascular and thoracic surgery 20121001

Title: Comparison of octreotide LAR and lanreotide autogel as post-operative medical treatment in acromegaly.

Journal: Pituitary 20120901

Title: Somatostatin analogs modulate AIP in somatotroph adenomas: the role of the ZAC1 pathway.

Journal: The Journal of clinical endocrinology and metabolism 20120801

Title: Systematic review and meta-analysis of somatostatin analogues for the treatment of pancreatic fistula.

Journal: The British journal of surgery 20120601

Title: Antitumor effects of somatostatin analogs in neuroendocrine tumors.

Journal: The oncologist 20120601

Title: Lanreotide treatment of metastatic hepatocellular carcinoma resulting in partial regression and more than 3 years of progression-free survival.

Journal: Acta gastro-enterologica Belgica 20120601

Title: A novel lanreotide-encoded micelle system targets paclitaxel to the tumors with overexpression of somatostatin receptors.

Journal: Molecular pharmaceutics 20120507

Title: Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass: the pathophysiological role of GLP1 and its response to a somatostatin analogue.

Journal: European journal of endocrinology 20120501

Title: Somatostatin analogues for the treatment of enterocutaneous fistulas: a systematic review and meta-analysis.

Journal: World journal of surgery 20120501

Title: Unusually aggressive type 1 gastric carcinoid: a case report with a review of the literature.

Journal: European journal of gastroenterology & hepatology 20120501

Title: Pharmacodynamic modeling of the effects of lanreotide Autogel on growth hormone and insulin-like growth factor 1.

Journal: Journal of clinical pharmacology 20120401

Title: Effects of chronic slow release-lanreotide treatment on insulin-like growth factor system and metabolic parameters in acromegalic patients.

Journal: Journal of endocrinological investigation 20120401

Title: Long acting somatostatin analogues in combination to antineoplastic agents in the treatment of small cell lung cancer patients.

Journal: Lung cancer (Amsterdam, Netherlands) 20120401

Title: Balance between somatostatin and D2 receptor expression drives TSH-secreting adenoma response to somatostatin analogues and dopastatins.

Journal: Clinical endocrinology 20120301

Title: Clinical review: Current scientific rationale for the use of somatostatin analogs and mTOR inhibitors in neuroendocrine tumor therapy.

Journal: The Journal of clinical endocrinology and metabolism 20120301

Title: Carcinoid crisis induced by repeated abdominal examination.

Journal: Internal medicine journal 20120301

Title: Practice guidance on the management of acute and chronic gastrointestinal problems arising as a result of treatment for cancer.

Journal: Gut 20120201

Title: Carcinoid tumour management in haemodialysis: a case report.

Journal: Nephrology (Carlton, Vic.) 20120201

Title: Update on the management of neuroendocrine tumors: focus on somatostatin antitumor effects.

Journal: Clinical journal of oncology nursing 20120201

Title: Lutetium-labelled peptides for therapy of neuroendocrine tumours.

Journal: European journal of nuclear medicine and molecular imaging 20120201

Title: Structural role of counterions adsorbed on self-assembled peptide nanotubes.

Journal: Journal of the American Chemical Society 20120111

Title: Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs).

Journal: Gut 20120101

Title: The long-term outcome of patients with polycystic liver disease treated with lanreotide.

Journal: Alimentary pharmacology & therapeutics 20120101

Title: Factors implicated in radiation therapy failure and radiosensitization of prostate cancer.

Journal: Prostate cancer 20120101

Title: Lanreotide depot deep subcutaneous injection: a new method of delivery and its associated benefits.

Journal: Patient preference and adherence 20120101

Title: Pregnant with metastatic neuroendocrine tumour of the ovary: what now?

Journal: Ecancermedicalscience 20120101

Title: Treatment Options in Cushing's Disease.

Journal: Clinical Medicine Insights. Oncology 20120101

Title: PLGA nanoparticles for peptide receptor radionuclide therapy of neuroendocrine tumors: a novel approach towards reduction of renal radiation dose.

Journal: PloS one 20120101

Title: Rationale and design of the RESOLVE trial: lanreotide as a volume reducing treatment for polycystic livers in patients with autosomal dominant polycystic kidney disease.

Journal: BMC nephrology 20120101

Title: Surgery and radiosurgery for acromegaly: a review of indications, operative techniques, outcomes, and complications.

Journal: International journal of endocrinology 20120101

Title: Gamma knife radiosurgery for acromegaly.

Journal: International journal of endocrinology 20120101

Title: Innovative oral treatments of uterine leiomyoma.

Journal: Obstetrics and gynecology international 20120101

Title: Treatment of liver metastases in patients with neuroendocrine tumors of gastroesophageal and pancreatic origin.

Journal: International journal of hepatology 20120101

Title: A multimodal approach to the management of neuroendocrine tumour liver metastases.

Journal: International journal of hepatology 20120101

Title: The Concept of Divergent Targeting through the Activation and Inhibition of Receptors as a Novel Chemotherapeutic Strategy: Signaling Responses to Strong DNA-Reactive Combinatorial Mimicries.

Journal: Journal of signal transduction 20120101

Title: Medical therapy of acromegaly.

Journal: International journal of endocrinology 20120101

Title: A first-in-man study to evaluate the safety, tolerability, and pharmacokinetics of pasireotide (SOM230), a multireceptor-targeted somatostatin analog, in healthy volunteers.

Journal: Drug design, development and therapy 20120101

Title: Meta-analysis on the effects of octreotide on tumor mass in acromegaly.

Journal: PloS one 20120101

Title: Preoperative lanreotide treatment improves outcome in patients with acromegaly resulting from invasive pituitary macroadenoma.

Journal: The Journal of international medical research 20120101

Title: Incidence of gall stone formation in acromegalic patients on octreotide therapy.

Journal: Indian journal of endocrinology and metabolism 20120101

Title: Prolonged survival in a patient with neuroendocrine tumor of the cecum and diffuse peritoneal carcinomatosis.

Journal: Case reports in gastroenterology 20120101

Title: Long-term lanreotide treatment in six patients with congenital hyperinsulinism.

Journal: Hormone research in paediatrics 20120101

Title: Preparation, characterization and related in vivo release, safety and toxicity studies of long acting lanreotide microspheres.

Journal: Biological & pharmaceutical bulletin 20120101

Title: The expanding role of somatostatin analogs in the management of neuroendocrine tumors.

Journal: Gastrointestinal cancer research : GCR 20120101

Title: Electronic and vibrational spectra of novel Lanreotide peptide capped gold nanoparticles.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101

Title: Clinical results of radionuclide therapy of neuroendocrine tumours with 90Y-DOTATATE and tandem 90Y/177Lu-DOTATATE: which is a better therapy option?

Journal: European journal of nuclear medicine and molecular imaging 20111001

Title: Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly.

Journal: European journal of endocrinology 20111001

Title: Systematic review and meta-analysis of the role of somatostatin and its analogues in the treatment of enterocutaneous fistula.

Journal: European journal of gastroenterology & hepatology 20111001

Title: Safety review: dose optimization of somatostatin analogs in patients with acromegaly and neuroendocrine tumors.

Journal: Advances in therapy 20111001

Title: The treatment of neuroendocrine tumors with long-acting somatostatin analogs: a single center experience with lanreotide autogel.

Journal: Journal of endocrinological investigation 20111001

Title: Conversion of daily pegvisomant to weekly pegvisomant combined with long-acting somatostatin analogs, in controlled acromegaly patients.

Journal: Pituitary 20110901

Title: Clinical, quality of life, and economic value of acromegaly disease control.

Journal: Pituitary 20110901

Title: Cotreatment with pegvisomant and a somatostatin analog (SA) in SA-responsive acromegalic patients.

Journal: The Journal of clinical endocrinology and metabolism 20110801

Title: Treatment of congenital hyperinsulinism with lanreotide acetate (Somatuline Autogel).

Journal: The Journal of clinical endocrinology and metabolism 20110801

Title: Results of endoscopic transsphenoidal pituitary surgery in 40 patients with a growth hormone-secreting macroadenoma.

Journal: Acta neurochirurgica 20110701

Title: Clinically silent somatotroph adenomas are common.

Journal: European journal of endocrinology 20110701

Title: Long-term results of treatment of malignant carcinoid syndrome with prolonged release Lanreotide (Somatuline Autogel).

Journal: Alimentary pharmacology & therapeutics 20110701

Title: Somatostatin receptors in non-neuroendocrine malignancies: the potential role of somatostatin analogs in solid tumors.

Journal: Future oncology (London, England) 20110701

Title: Rotavirus stimulates release of serotonin (5-HT) from human enterochromaffin cells and activates brain structures involved in nausea and vomiting.

Journal: PLoS pathogens 20110701

Title: Somatostatin analogues for treatment of polycystic liver disease.

Journal: Current opinion in gastroenterology 20110501

Title: Resistance to somatostatin analogs in acromegaly.

Journal: Endocrine reviews 20110401

Title: A review of systemic and liver-directed therapies for metastatic neuroendocrine tumors of the gastroenteropancreatic tract.

Journal: Cancer control : journal of the Moffitt Cancer Center 20110401

Title: Efficacy and acceptability of lanreotide Autogel® 120 mg at different dose intervals in patients with acromegaly previously treated with octreotide LAR.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20110301

Title: Lanreotide autogel-induced tumour shrinkage in thyrotropin-secreting pituitary macroadenomas.

Journal: Clinical endocrinology 20110301

Title: Coadministration of lanreotide Autogel and pegvisomant normalizes IGF1 levels and is well tolerated in patients with acromegaly partially controlled by somatostatin analogs alone.

Journal: European journal of endocrinology 20110301

Title: Chemoprevention of hepatocellular carcinoma. Proof of concept in animal models.

Journal: Acta gastro-enterologica Belgica 20110301

Title: Use of lanreotide for the treatment of gastrointestinal fistulae.

Journal: Annals of surgery 20110101

Title: Clinical efficacy and safety results for dose escalation of somatostatin receptor ligands in patients with acromegaly: a literature review.

Journal: Pituitary 20110101

Title: ADPKD: Prototype of Cardiorenal Syndrome Type 4.

Journal: International journal of nephrology 20110101

Title: [Neuroendocrine target therapies for prostate cancer].

Journal: Urologia 20110101

Title: Protein attributes contribute to halo-stability, bioinformatics approach.

Journal: Saline systems 20110101

Title: Molecular SPECT Imaging: An Overview.

Journal: International journal of molecular imaging 20110101

Title: Acromegaly associated with a symptomatic Rathke's cyst.

Journal: Indian journal of endocrinology and metabolism 20110101

Title: Regulation of bombesin-stimulated cyclooxygenase-2 expression in prostate cancer cells.

Journal: BMC molecular biology 20110101

Title: Uneventful octreotide LAR therapy throughout three pregnancies, with favorable delivery and anthropometric measures for each newborn: a case report.

Journal: Journal of medical case reports 20110101

Title: Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia.

Journal: PloS one 20110101

Title: Treatment of liver metastases in patients with neuroendocrine tumors: a comprehensive review.

Journal: International journal of hepatology 20110101

Title: Sporadic and genetic forms of paediatric somatotropinoma: a retrospective analysis of seven cases and a review of the literature.

Journal: Orphanet journal of rare diseases 20110101

Title: Everolimus and long acting octreotide as a volume reducing treatment of polycystic livers (ELATE): study protocol for a randomized controlled trial.

Journal: Trials 20110101

Title: Effect of Peptide Receptor Radionuclide Therapy on Somatostatin Receptor Status and Glucose Metabolism in Neuroendocrine Tumors: Intraindividual Comparison of Ga-68 DOTANOC PET/CT and F-18 FDG PET/CT.

Journal: International journal of molecular imaging 20110101

Title: Selective internal radiation therapy for gastrointestinal neuroendocrine tumour liver metastases: a new and effective modality for treatment.

Journal: International journal of hepatology 20110101

Title: Cancer and renal insufficiency results of the BIRMA study.

Journal: British journal of cancer 20101207

Title: Large fat and skin necroses after deep subcutaneous injections of a slow-release somatostatin analogue in a woman with acromegaly.

Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20101201

Title: Pharmacokinetic evaluation of lanreotide.

Journal: Expert opinion on drug metabolism & toxicology 20101001

Title: Pharmacological management of acromegaly: a current perspective.

Journal: Neurosurgical focus 20101001

Title: Octreotide long-acting release (LAR): a review of its use in the management of acromegaly.

Journal: Drugs 20100910

Title: The endocrine tumor summit 2008: appraising therapeutic approaches for acromegaly and carcinoid syndrome.

Journal: Pituitary 20100901

Title: Adverse anthropometric risk profile in biochemically controlled acromegalic patients: comparison with an age- and gender-matched primary care population.

Journal: Pituitary 20100901

Title: Medical therapy of acromegaly in Turkey.

Journal: Journal of endocrinological investigation 20100901

Title: Effects of a long-acting somatostatin analogue, lanreotide, on bile duct ligation-induced liver fibrosis in rats.

Journal: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20100901

Title: Unexplained iron deficiency anaemia: Is it worthwhile to perform capsule endoscopy?

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20100801

Title: [Leonine facies in carcinoid syndrome].

Journal: Actas dermo-sifiliograficas 20100701

Title: Antiproliferative effect of somatostatin analogs in gastroenteropancreatic neuroendocrine tumors.

Journal: World journal of gastroenterology 20100628

Title: Long-acting somatostatin analogue therapy in obscure-overt gastrointestinal bleeding in noncirrhotic portal hypertension: a case report and literature review.

Journal: European journal of gastroenterology & hepatology 20100601

Title: Management of acromegaly in Latin America: expert panel recommendations.

Journal: Pituitary 20100601

Title: Effectiveness of self- or partner-administration of an extended-release aqueous-gel formulation of lanreotide in lanreotide-naïve patients with acromegaly.

Journal: Pituitary 20100601

Title: Objective radiological disease control with sandostatin monotherapy in metastatic neuroendocrine tumours.

Journal: Internal medicine journal 20100601

Title: Complete disappearance of a GH-secreting pituitary macroadenoma in a patient with acromegaly: effect of treatment with lanreotide Autogel and consequence of treatment withdrawal.

Journal: European journal of endocrinology 20100501

Title: From then to now: lessons from developments in our understanding of the pituitary gland.

Journal: The Ulster medical journal 20100501

Title: Preoperative lanreotide treatment in acromegalic patients with macroadenomas increases short-term postoperative cure rates: a prospective, randomised trial.

Journal: European journal of endocrinology 20100401

Title: Therapeutic 188Re-lanreotide: determination of radiopharmacokinetic parameters in rats.

Journal: The Journal of pharmacy and pharmacology 20100401

Title: Elucidation of the self-assembly pathway of lanreotide octapeptide into beta-sheet nanotubes: role of two stable intermediates.

Journal: Journal of the American Chemical Society 20100331

Title: Rapid and sustained reduction of serum growth hormone and insulin-like growth factor-1 in patients with acromegaly receiving lanreotide Autogel therapy: a randomized, placebo-controlled, multicenter study with a 52 week open extension.

Journal: Pituitary 20100301

Title: Somatostatin-receptor-based imaging and therapy of gastroenteropancreatic neuroendocrine tumors.

Journal: Endocrine-related cancer 20100301

Title: Corticosteroids in the medical treatment of thyroid ophthalmopathy: when and how? Somatostatin analogues: where we stand today.

Journal: Pediatric endocrinology reviews : PER 20100301

Title: Novel treatment modalities for Graves' orbitopathy.

Journal: Pediatric endocrinology reviews : PER 20100301

Title: Regulation of prostate cancer cell proliferation by somatostatin receptor activation.

Journal: Molecular and cellular endocrinology 20100205

Title: Aftercare in patients with Cushing's disease and acromegaly: is there room for improvement?

Journal: Acta neurochirurgica 20100201

Title: [Management of acromegaly in pregnant woman].

Journal: Annales d'endocrinologie 20100201

Title: Twelve years of the Spanish acromegaly registry: a historical view of acromegaly management in Spain.

Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20100201

Title: Review article: somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine (carcinoid) tumours.

Journal: Alimentary pharmacology & therapeutics 20100115

Title: Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats.

Journal: Chemico-biological interactions 20100105

Title: Effects of lanreotide SR and Autogel on tumor mass in patients with acromegaly: a systematic review.

Journal: Pituitary 20100101

Title: Reduction of elevated IGF-1 levels in coincident amyotrophic lateral sclerosis and acromegaly.

Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20100101

Title: A single-center open-label study to investigate the efficacy and safety of repeated subcutaneous injections of lanreotide Autogel in patients with acromegaly previously treated with octreotide.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20100101

Title: Carcinoid encephalopathy: A single entity or a spectrum of different disorders?

Journal: Acta oncologica (Stockholm, Sweden) 20100101

Title: [Nelson syndrome: a rare cause of generalized hyperpigmentation of the skin].

Journal: Actas dermo-sifiliograficas 20100101

Title: Primary carcinoid tumor of the gallbladder: a case report and brief review of the literature.

Journal: World journal of surgical oncology 20100101

Title: Somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine tumours, current aspects and new perspectives.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Primary treatment of acromegaly with high-dose lanreotide: a case series.

Journal: Journal of medical case reports 20100101

Title: Relative bioavailability of two drug products of somatropin obtained from either the milk of transgenic cows or bacterial culture.

Journal: Hormone research in paediatrics 20100101

Title: Prolactinomas, Cushing's disease and acromegaly: debating the role of medical therapy for secretory pituitary adenomas.

Journal: BMC endocrine disorders 20100101

Title: SSTR1 and SSTR5 subtypes are the dominant forms of somatostatin receptor in neuroendocrine tumors.

Journal: Folia histochemica et cytobiologica 20100101

Title: Somatostatin analogues: treatment of pituitary and neuroendocrine tumors.

Journal: Progress in brain research 20100101

Title: Long term treatment of a thyrotropin-secreting microadenoma with somatostatin analogues.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20100101

Title: Biological characteristics and treatment outcomes of metastatic or recurrent neuroendocrine tumors: tumor grade and metastatic site are important for treatment strategy.

Journal: BMC cancer 20100101

Title: Molecular and other novel advances in treatment of metastatic epithelial and medullary thyroid cancers.

Journal: Journal of oncology 20100101

Title: Materials for pharmaceutical dosage forms: molecular pharmaceutics and controlled release drug delivery aspects.

Journal: International journal of molecular sciences 20100101

Title: Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment.

Journal: Journal of translational medicine 20100101

Title: Treatment of Cushing disease: overview and recent findings.

Journal: Therapeutics and clinical risk management 20100101

Title: Metastatic carcinoid tumour of the heart.

Journal: Archives of cardiovascular diseases 20100101

Title: Remission of Merkel cell tumor after somatostatin analog treatment.

Journal: Journal of cancer research and therapeutics 20100101

Title: Differential expression of microRNAs in GH-secreting pituitary adenomas.

Journal: Diagnostic pathology 20100101

Title: XAF1 expression and regulatory effects of somatostatin on XAF1 in prostate cancer cells.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Management of acromegaly.

Journal: F1000 medicine reports 20100101

Title: Somatostatin and dopamine receptors.

Journal: Tumori 20100101

Title: Perspectives in the development of novel treatment approaches.

Journal: Tumori 20100101

Title: Advances in the treatment of gastroenteropancreatic neuroendocrine tumors.

Journal: Clinical and experimental gastroenterology 20100101

Title: Palliative management of malignant bowel obstruction in terminally ill patient.

Journal: Indian journal of palliative care 20100101

Title: Randomized, placebo-controlled, double-blind study of the efficacy of lanreotide 30 mg PR in the treatment of pancreatic and enterocutaneous fistulae.

Journal: Annals of surgery 20091201

Title: Medical therapy of acromegaly: efficacy and safety of somatostatin analogues.

Journal: Drugs 20091112

Title: Tumor ZAC1 expression is associated with the response to somatostatin analog therapy in patients with acromegaly.

Journal: International journal of cancer 20091101

Title: Lanreotide reduces the volume of polycystic liver: a randomized, double-blind, placebo-controlled trial.

Journal: Gastroenterology 20091101

Title: Differential ligand-mediated pituitary somatostatin receptor subtype signaling: implications for corticotroph tumor therapy.

Journal: The Journal of clinical endocrinology and metabolism 20091101

Title: Octreotide LAR: safety and tolerability issues.

Journal: Expert opinion on drug safety 20091101

Title: Effects of initial therapy for five years with somatostatin analogs for acromegaly on growth hormone and insulin-like growth factor-I levels, tumor shrinkage, and cardiovascular disease: a prospective study.

Journal: The Journal of clinical endocrinology and metabolism 20091001

Title: Pituitary tumours: TSH-secreting adenomas.

Journal: Best practice & research. Clinical endocrinology & metabolism 20091001

Title: Future treatment strategies of aggressive pituitary tumors.

Journal: Pituitary 20090901

Title: Pituitary-hormone secretion by thyrotropinomas.

Journal: Pituitary 20090901

Title: Lanreotide promotes apoptosis and is not radioprotective in GH3 cells.

Journal: Endocrine-related cancer 20090901

Title: Somatostatin and somatostatin receptors: implications for neoplastic growth and cancer biology.

Journal: Expert opinion on investigational drugs 20090901

Title: Pathology, pathogenesis and therapy of growth hormone (GH)-producing pituitary adenomas: technical advances in histochemistry and their contribution.

Journal: Acta histochemica et cytochemica 20090829

Title: Significant tumour shrinkage after 12 months of lanreotide Autogel-120 mg treatment given first-line in acromegaly.

Journal: Clinical endocrinology 20090801

Title: Pituitary tumors.

Journal: Current treatment options in neurology 20090701

Title: Somatostatin-dopamine ligands in the treatment of pituitary adenomas.

Journal: Reviews in endocrine & metabolic disorders 20090601

Title: Cost-effectiveness of lanreotide Autogel in treatment algorithms of acromegaly.

Journal: Expert review of pharmacoeconomics & outcomes research 20090601

Title: Lanreotide for the treatment of acromegaly.

Journal: Advances in therapy 20090601

Title: Non-epithelial malignancies and metastatic tumours of the breast.

Journal: The Ulster medical journal 20090501

Title: Cyclic ectopic Cushing's syndrome and somatostatin analogue treatment.

Journal: The New Zealand medical journal 20090424

Title: IL1beta- and LPS-induced serotonin secretion is increased in EC cells derived from Crohn's disease.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090401

Title: Combined treatment for acromegaly with long-acting somatostatin analogs and pegvisomant: long-term safety for up to 4.5 years (median 2.2 years) of follow-up in 86 patients.

Journal: European journal of endocrinology 20090401

Title: A combined in vitro and in vivo study on the interactions between somatostatin and lipid-based liquid crystalline drug carriers and bilayers.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090302

Title: Efficacy of the new long-acting formulation of lanreotide (lanreotide Autogel) in somatostatin analogue-naive patients with acromegaly.

Journal: Journal of endocrinological investigation 20090301

Title: The oral multitarget tumour growth inhibitor, ZK 304709, inhibits growth of pancreatic neuroendocrine tumours in an orthotopic mouse model.

Journal: Gut 20090201

Title: Differential effects of octreotide and pasireotide on somatostatin receptor internalization and trafficking in vitro.

Journal: The Journal of clinical endocrinology and metabolism 20090201

Title: Impact of somatostatin analogs versus surgery on glucose metabolism in acromegaly: results of a 5-year observational, open, prospective study.

Journal: The Journal of clinical endocrinology and metabolism 20090201

Title: Somatostatin analog lanreotide in the treatment of castration-resistant prostate cancer (CRPC).

Journal: Expert opinion on pharmacotherapy 20090201

Title: [Acromegalic myocardiopathy].

Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20090201

Title: Population pharmacokinetic analysis of lanreotide Autogel in healthy subjects : evidence for injection interval of up to 2 months.

Journal: Clinical pharmacokinetics 20090101

Title: ACROSTUDY: Status Update on 469 Patients.

Journal: Hormone research 20090101

Title: Expression of somatostatin receptor subtypes in human thyroid tumors: the immunohistochemical and molecular biology (RT-PCR) investigation.

Journal: Thyroid research 20090101

Title: A comprehensive overview of radioguided surgery using gamma detection probe technology.

Journal: World journal of surgical oncology 20090101

Title: Long-acting lanreotide in adolescent girls with constitutional tall stature.

Journal: Hormone research 20090101

Title: Efficacy of long-term lanreotide treatment in patients with acromegaly.

Journal: Pituitary 20090101

Title: [Application of somatulin in the treatment of complications after operations on the pancreatic gland].

Journal: Klinichna khirurhiia 20090101

Title: Expression of somatostatin receptor subtypes in human pituitary adenomas -- immunohistochemical studies.

Journal: Endokrynologia Polska 20090101

Title: Clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review and economic evaluation.

Journal: BMC endocrine disorders 20090101

Title: Continuous 5-fluorouracil infusion plus long acting octreotide in advanced well-differentiated neuroendocrine carcinomas. A phase II trial of the Piemonte oncology network.

Journal: BMC cancer 20090101

Title: Octreotide treatment of patients with hepatocellular carcinoma--a retrospective single centre controlled study.

Journal: Journal of experimental & clinical cancer research : CR 20090101

Title: Primary liver carcinoid tumour with a Zollinger Ellison syndrome - an unusual diagnosis: a case report.

Journal: Cases journal 20090101

Title: Carcinoid tumor of the kidney: An unusual renal tumor.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20090101

Title: Medical treatment of Cushing's disease: Overview and recent findings.

Journal: International journal of general medicine 20090101

Title: Antiproliferative effects of somatostatin analogs in endocrine tumours.

Journal: F1000 medicine reports 20090101

Title: [Efficacy of prolonged-release somatostatin analog monotherapy in metastatic endocrine tumors].

Journal: Gastroenterologie clinique et biologique 20081201

Title: Somatostatin 2A receptor-expressing presympathetic neurons in the rostral ventrolateral medulla maintain blood pressure.

Journal: Hypertension (Dallas, Tex. : 1979) 20081201

Title: Cost-effectiveness analysis of somatostatin analogues in the treatment of acromegaly in Brazil.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20081201

Title: Para-aortic lymphocele treated with an injection of somatostatine analog (lanreotide).

Journal: European journal of obstetrics, gynecology, and reproductive biology 20081101

Title: Octreotide-LAR vs lanreotide-SR as first-line therapy for acromegaly: a retrospective, comparative, head-to-head study.

Journal: Journal of endocrinological investigation 20081101

Title: [Peritoneal mesothelioma: long survival with intraperitoneal chemotherapy, lanreotide and mucolytics].

Journal: Gastroenterologie clinique et biologique 20081001

Title: Long-acting somatostatin analogues are an effective treatment for type 1 gastric carcinoid tumours.

Journal: European journal of endocrinology 20081001

Title: Effects of lanreotide Autogel on growth hormone, insulinlike growth factor 1, and tumor size in acromegaly: a 1-year prospective multicenter study.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20081001

Title: Mechanisms of action and resistance of somatostatin analogues for the treatment of hepatocellular carcinoma: a message not well taken.

Journal: Digestive diseases and sciences 20080901

Title: Somatostatin analogues reduce liver volume in polycystic liver disease.

Journal: Gut 20080901

Title: [New medical treatments in pituitary adenomas].

Journal: Annales d'endocrinologie 20080901

Title: Therapeutic options in the management of acromegaly: focus on lanreotide Autogel.

Journal: Biologics : targets & therapy 20080901

Title: Differential cytotoxicity of novel somatostatin and dopamine chimeric compounds on bronchopulmonary and small intestinal neuroendocrine tumor cell lines.

Journal: Cancer 20080815

Title: The combination of docetaxel and the somatostatin analogue lanreotide on androgen-independent docetaxel-resistant prostate cancer: experimental data.

Journal: BJU international 20080805

Title: Control of IGF-I levels with titrated dosing of lanreotide Autogel over 48 weeks in patients with acromegaly.

Journal: Clinical endocrinology 20080801

Title: A critical analysis of clinically available somatostatin analog formulations for therapy of acromegaly.

Journal: The Journal of clinical endocrinology and metabolism 20080801

Title: What the similarities of specific polycystic liver and kidney diseases can teach us about both.

Journal: Nephrology news & issues 20080801

Title: New drugs08, part 2.

Journal: Nursing 20080701

Title: [Biotherapy of neuroendocrine tumours of the gastrointestinal tract and pancreas].

Journal: Ugeskrift for laeger 20080609

Title: Surgical debulking of pituitary macroadenomas causing acromegaly improves control by lanreotide.

Journal: Clinical endocrinology 20080601

Title: Predictors of early re-bleeding and mortality after acute variceal haemorrhage in patients with cirrhosis.

Journal: Gut 20080601

Title: Lanreotide Autogel for persistent diabetic macular edema.

Journal: Diabetes research and clinical practice 20080601

Title: No greater incidence or worsening of cardiac valve regurgitation with somatostatin analog treatment of acromegaly.

Journal: The Journal of clinical endocrinology and metabolism 20080601

Title: Emerging drugs for acromegaly.

Journal: Expert opinion on emerging drugs 20080601

Title: Somatostatin agonists for treatment of acromegaly.

Journal: Molecular and cellular endocrinology 20080514

Title: Gluteal nodules in patients with metastatic midgut carcinoid disease treated with depot somatostatin analogs.

Journal: The Journal of clinical endocrinology and metabolism 20080501

Title: Complete response to the combination therapy with androgen blockade and somatostatin analogue in a patient with advanced prostate cancer: magnetic resonance imaging with 1H-spectroscopy.

Journal: European urology 20080301

Title: Home administration of lanreotide Autogel by patients with acromegaly, or their partners, is safe and effective.

Journal: Clinical endocrinology 20080301

Title: A 12-month randomized crossover study on the effects of lanreotide Autogel and octreotide long-acting repeatable on GH and IGF-l in patients with acromegaly.

Journal: Clinical endocrinology 20080301

Title: Molecular origin of the self-assembly of lanreotide into nanotubes: a mutational approach.

Journal: Biophysical journal 20080301

Title: Consensus statement of the Polish Society for Endocrinology: presurgical somatostatin analogs therapy in acromegaly.

Journal: Neuro endocrinology letters 20080201

Title: Association of malignant insulinoma and type 2 diabetes mellitus: a case report.

Journal: Annales d'endocrinologie 20080201

Title: Octreotide-LAR-associated erythema multiforme in an acromegalic subject: case report.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20080201

Title: Novel therapeutic strategies for neuroendocrine tumours--can eminence replace evidence?

Journal: Acta oncologica (Stockholm, Sweden) 20080101

Title: Self-assembly of the octapeptide lanreotide and lanreotide-based derivatives: the role of the aromatic residues.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20080101

Title: Acromegaly and anaplastic astrocytoma: coincidence or pathophysiological relation?

Journal: Pituitary 20080101

Title: The role of nitric oxide and cGMP in somatostatin's protection against retinal ischemia.

Journal: Investigative ophthalmology & visual science 20080101

Title: Chylous ascites following radical nephrectomy: a case report.

Journal: Journal of medical case reports 20080101

Title: Lanreotide Autogel: a review of its use in the management of acromegaly.

Journal: Drugs 20080101

Title: Lanreotide Autogel in the management of acromegaly.

Journal: Drugs 20080101

Title: Surgical treatment of a rare primary renal carcinoid tumor with liver metastasis.

Journal: World journal of surgical oncology 20080101

Title: Acromegaly.

Journal: Orphanet journal of rare diseases 20080101

Title: [Application of preparations--analogues of somatostatin in surgical pancreatology].

Journal: Klinichna khirurhiia 20080101

Title: Spotlight on lanreotide Autogel in acromegaly.

Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20080101

Title: Use of somatostatin analogues in obesity.

Journal: Drugs 20080101

Title: Primary hepatic carcinoid; a diagnostic dilemma: a case report.

Journal: Cases journal 20080101

Title: Octreotide in Palliative Treatment of Unresectable Cholangiocarcinoma: Is it Effective for Disease Stabilization?

Journal: Clinical medicine. Oncology 20080101

Title: Octreotide in Palliative Treatment of Hepatic Metastases: Is it Effective for Clinical Stabilization?

Journal: Clinical medicine. Oncology 20080101

Title: Inhibition of early preneoplastic events in the rat liver by the somatostatin analog lanreotide.

Journal: Cancer science 20071201

Title: Is surgery indicated for patients with symptomatic nonfunctioning pancreatic neuroendocrine tumor and unresectable hepatic metastases?

Journal: World journal of surgery 20071201

Title: Pasireotide--a somatostatin analog for the potential treatment of acromegaly, neuroendocrine tumors and Cushing's disease.

Journal: IDrugs : the investigational drugs journal 20071201

Title: Lanreotide autogel and insulin sensitivity markers: report of 5 acromegalic patients and literature review.

Journal: Neuro endocrinology letters 20071201

Title: Radiation recall dermatitis in a patient affected with pheochromocytoma after treatment with lanreotide.

Journal: The British journal of dermatology 20071101

Title: Optimalization and cost management of lanreotide-Autogel therapy in acromegaly.

Journal: European journal of endocrinology 20071101

Title: A comparison of the effects of gastrin, somatostatin and dopamine receptor ligands on rat gastric enterochromaffin-like cell secretion and proliferation.

Journal: Regulatory peptides 20071004

Title: Efficacy of a slow-release formulation of lanreotide (Autogel) 120 mg) in patients with acromegaly previously treated with octreotide long acting release (LAR): an open, multicentre longitudinal study.

Journal: Clinical endocrinology 20071001

Title: Application of MR spectroscopy and treatment approaches in a patient with extrapituitary growth hormone secreting macroadenoma.

Journal: Neuro endocrinology letters 20071001

Title: Acromegaly caused by growth hormone-releasing hormone-producing tumors: long-term observational studies in three patients.

Journal: Pituitary 20070901

Title: Tailored intermittent therapy of carcinoid.

Journal: Hepato-gastroenterology 20070901

Title: The efficacy of somatostatin analogues in the treatment of diabetic retinopathy and thyroid eye disease.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20070901

Title: Efficacy of the combination of long-acting release octreotide and tamoxifen in patients with advanced hepatocellular carcinoma: a randomised multicentre phase III study.

Journal: British journal of cancer 20070828

Title: Long-term (up to 18 years) effects on GH/IGF-1 hypersecretion and tumour size of primary somatostatin analogue (SSTa) therapy in patients with GH-secreting pituitary adenoma responsive to SSTa.

Journal: Clinical endocrinology 20070801

Title: Hierarchical architectures by synergy between dynamical template self-assembly and biomineralization.

Journal: Nature materials 20070601

Title: Biomimetic synthesis: Double-walled silica nanotubes.

Journal: Nature materials 20070601

Title: Chemo-hormone therapy of non-well-differentiated endocrine tumours from different anatomic sites with cisplatinum, etoposide and slow release lanreotide formulation.

Journal: British journal of cancer 20070507

Title: Impact of somatostatin analogs on the heart in acromegaly: a metaanalysis.

Journal: The Journal of clinical endocrinology and metabolism 20070501

Title: Withdrawal of somatostatin analogue therapy in patients with acromegaly is associated with an increased risk of acute biliary problems.

Journal: Clinical endocrinology 20070501

Title: Growth hormone excess with onset in adolescence: clinical appearance and long-term treatment outcome.

Journal: Clinical endocrinology 20070501

Title: N-terminal pro-B-type natriuretic peptide in patients with growth hormone disturbances.

Journal: Clinical endocrinology 20070501

Title: Chemotherapy in advanced biliary tract carcinoma: a pooled analysis of clinical trials.

Journal: British journal of cancer 20070326

Title: Intestinal lymphangiectasia: a rare cause of gastrointestinal bleeding?

Journal: Scandinavian journal of gastroenterology 20070301

Title: [Octreotide scintigraphy in thyroid orbitopathy].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20070301

Title: Further delineation of the continuous human neoplastic enterochromaffin cell line, KRJ-I, and the inhibitory effects of lanreotide and rapamycin.

Journal: Journal of molecular endocrinology 20070201

Title: A review of the current clinical trials for gastroenteropancreatic neuroendocrine tumours.

Journal: Expert opinion on investigational drugs 20070201

Title: Evaluating the activity of temsirolimus in neuroendocrine cancer.

Journal: British journal of cancer 20070115

Title: [Somatostatin analogue treatment in Graves' ophthalmopathy: a case report].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20070101

Title: Clinical radionuclide therapy dosimetry: the quest for the 'Holy Gray'.

Journal: European journal of nuclear medicine and molecular imaging 20070101

Title: Severe hypercalcaemia and lymphoma in an HTLV-1 positive Jamaican woman: a case report.

Journal: Journal of medical case reports 20070101

Title: Medical treatment of gastrinomas.

Journal: Wiener klinische Wochenschrift 20070101

Title: New drugs: Maraviroc and Lanreotide.

Journal: Journal of the American Pharmacists Association : JAPhA 20070101

Title: [Consensus of the Polish Society of Endocrinology. Presurgical somatostatin analogs therapy in acromegaly].

Journal: Endokrynologia Polska 20070101

Title: Rationale for the use of somatostatin analogs as antitumor agents.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20061201

Title: [Treatment of pituitary gland hyperfunction: from acromegaly to prolactinoma].

Journal: Der Internist 20061201

Title: Associations of remission status and lanreotide treatment with quality of life in patients with treated acromegaly.

Journal: European journal of endocrinology 20061201

Title: Nanomedicines in the treatment of acromegaly: focus on pegvisomant.

Journal: International journal of nanomedicine 20061201

Title: Lanreotide autogel every 6 weeks compared with Lanreotide microparticles every 3 weeks in patients with well differentiated neuroendocrine tumors: a Phase III Study.

Journal: Cancer 20061115

Title: Somatostatin receptor expression, tumour response, and quality of life in patients with advanced hepatocellular carcinoma treated with long-acting octreotide.

Journal: British journal of cancer 20061009

Title: TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system.

Journal: Virchows Archiv : an international journal of pathology 20061001

Title: Dissociation between tumor shrinkage and hormonal response during somatostatin analog treatment in an acromegalic patient: preferential expression of somatostatin receptor subtype 3.

Journal: Journal of endocrinological investigation 20061001

Title: Thyroid-associated ophthalmopathy in juvenile Graves' disease--clinical, endocrine and therapeutic aspects.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20061001

Title: [Somatostatin analogs].

Journal: Polskie Archiwum Medycyny Wewnetrznej 20061001

Title: Efficacy of lanreotide Autogel administered every 4-8 weeks in patients with acromegaly previously responsive to lanreotide microparticles 30 mg: a phase III trial.

Journal: Clinical endocrinology 20060901

Title: TSH-induced hyperthyroidism caused by a pituitary tumor.

Journal: Nature clinical practice. Endocrinology & metabolism 20060901

Title: Lanreotide on collateral response to endothelin-1 and vasopressin in cirrhotic rats.

Journal: Journal of the Chinese Medical Association : JCMA 20060901

Title: Long-term primary medical therapy with somatostatin analogs in acromegaly.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20060801

Title: Newer options in the management of acromegaly.

Journal: Internal medicine journal 20060701

Title: Combination therapy using LHRH and somatostatin analogues plus dexamethasone in androgen ablation refractory prostate cancer patients with bone involvement: a bench to bedside approach.

Journal: Expert opinion on investigational drugs 20060701

Title: Effects of the long-acting somatostatin analogue Lanreotide Autogel on glucose tolerance and insulin resistance in acromegaly.

Journal: European journal of endocrinology 20060701

Title: Role of somatostatin analogs in the clinical management of non-neuroendocrine solid tumors.

Journal: Anti-cancer drugs 20060701

Title: Predictors of tumor shrinkage after primary therapy with somatostatin analogs in acromegaly: a prospective study in 99 patients.

Journal: The Journal of clinical endocrinology and metabolism 20060601

Title: Selective activation of somatostatin receptor subtypes differentially modulates secretion and viability in human medullary thyroid carcinoma primary cultures: potential clinical perspectives.

Journal: The Journal of clinical endocrinology and metabolism 20060601

Title: The place of somatostatin analogs in the diagnosis and treatment of the neuoroendocrine glands tumors.

Journal: Recent patents on anti-cancer drug discovery 20060601

Title: Slow-release lanreotide in Graves' ophthalmopathy: A double-blind randomized, placebo-controlled clinical trial.

Journal: Journal of endocrinological investigation 20060501

Title: New perspective in the management of neuroendocrine differentiation in prostate adenocarcinoma.

Journal: International journal of clinical practice 20060401

Title: Guidelines for the diagnosis and management of carcinoid tumours. Part 1: the gastrointestinal tract. A statement from a Canadian National Carcinoid Expert Group.

Journal: Current oncology (Toronto, Ont.) 20060401

Title: Radiopharmacokinetic and dosimetric parameters of 188Re-lanreotide in athymic mice with induced human cancer tumors.

Journal: International journal of pharmaceutics 20060309

Title: Efficacy of 12-month treatment with the GH receptor antagonist pegvisomant in patients with acromegaly resistant to long-term, high-dose somatostatin analog treatment: effect on IGF-I levels, tumor mass, hypertension and glucose tolerance.

Journal: European journal of endocrinology 20060301

Title: Effectiveness and tolerability of 3-year lanreotide Autogel treatment in patients with acromegaly.

Journal: Clinical endocrinology 20060201

Title: Pharmacologic therapy for gastrointestinal bleeding due to portal hypertension and esophageal varices.

Journal: Current gastroenterology reports 20060201

Title: Partial surgical removal of growth hormone-secreting pituitary tumors enhances the response to somatostatin analogs in acromegaly.

Journal: The Journal of clinical endocrinology and metabolism 20060101

Title: Treatment of advanced carcinoid tumors.

Journal: Current opinion in oncology 20060101

Title: Resistance to somatostatin analogs in acromegaly: an evolving concept?

Journal: Journal of endocrinological investigation 20060101

Title: Disappearance of a growth hormone secreting macro adenoma during long-term somatostatin analogue administration and recurrence following somatostatin withdrawal.

Journal: Hormones (Athens, Greece) 20060101

Title: [Somatostatin analogues in treatment of gastrointestinal and pancreatic neuroendocrine tumors].

Journal: Klinicheskaia meditsina 20060101

Title: Management of acute pancreatitis: current knowledge and future perspectives.

Journal: World journal of emergency surgery : WJES 20060101

Title: Liver metastases of neuroendocrine tumours; early reduction of tumour load to improve life expectancy.

Journal: World journal of surgical oncology 20060101

Title: Acromegaly: molecular expression of somatostatin receptor subtypes and treatment outcome.

Journal: Frontiers of hormone research 20060101

Title: Pharmacokinetic profile of the somatostatin analogue lanreotide in individuals with chronic hepatic insufficiency.

Journal: Clinical pharmacokinetics 20060101

Title: Medical treatment of acromegaly: comorbidities and their reversibility by somatostatin analogs.

Journal: Neuroendocrinology 20060101

Title: Lethal somatostatin analog-induced acute necrotizing pancreatitis in a patient with hormone-refractory prostate cancer.

Journal: Scandinavian journal of urology and nephrology 20060101

Title: Somatostatin and dopamine receptor expression in lung carcinoma cells and effects of chimeric somatostatin-dopamine molecules on cell proliferation.

Journal: American journal of physiology. Endocrinology and metabolism 20051201

Title: Treatment of advanced neuroendocrine tumours with radiolabelled somatostatin analogues.

Journal: Endocrine-related cancer 20051201

Title: Pharmacokinetic profile of lanreotide Autogel in patients with acromegaly after four deep subcutaneous injections of 60, 90 or 120 mg every 28 days.

Journal: Clinical endocrinology 20051101

Title: Pharmacokinetics and population pharmacodynamic analysis of lanreotide Autogel.

Journal: Metabolism: clinical and experimental 20051001

Title: Treatment of pituitary tumors: somatostatin.

Journal: Endocrine 20051001

Title: Symptomatic control of hypoglycaemia with prednisone in refractory metastatic pancreatic insulinoma.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20050901

Title: Camptothecin-somatostatin conjugates inhibit the growth of small cell lung cancer cells.

Journal: Peptides 20050901

Title: Effect of gender and gonadal status on the long-term response to somatostatin analogue treatment in acromegaly.

Journal: Clinical endocrinology 20050901

Title: Long-acting somatostatin analog therapy of acromegaly: a meta-analysis.

Journal: The Journal of clinical endocrinology and metabolism 20050801

Title: The clinical characteristics of headache in patients with pituitary tumours.

Journal: Brain : a journal of neurology 20050801

Title: Endocrine tumours of the gastrointestinal tract. Biotherapy for metastatic endocrine tumours.

Journal: Best practice & research. Clinical gastroenterology 20050801

Title: A critical analysis of pituitary tumor shrinkage during primary medical therapy in acromegaly.

Journal: The Journal of clinical endocrinology and metabolism 20050701

Title: Long-acting octreotide and prolonged-release lanreotide formulations have different pharmacokinetic profiles.

Journal: Journal of clinical pharmacology 20050701

Title: Cabergoline plus lanreotide for ectopic Cushing's syndrome.

Journal: The New England journal of medicine 20050609

Title: Binding and functional properties of the novel somatostatin analogue KE 108 at native mouse somatostatin receptors.

Journal: Neuropharmacology 20050501

Title: Role of medical therapy in the management of acromegaly.

Journal: Neurosurgery 20050501

Title: Combined therapy with somatostatin analogues and weekly pegvisomant in active acromegaly.

Journal: Lancet (London, England) 20050501

Title: Indium111 pentetreotide single photon emission computed tomography (In111 pentetreotide SPECT): a new technique to evaluate somatostatin receptors in chordomas.

Journal: The Journal of laryngology and otology 20050501

Title: Regression of liver metastases of occult carcinoid tumor with slow release lanreotide therapy.

Journal: World journal of gastroenterology 20050407

Title: Somatostatin analogs in vitro effects in a growth hormone-releasing hormone-secreting bronchial carcinoid.

Journal: The Journal of clinical endocrinology and metabolism 20050401

Title: Changes in the expression of somatostatin receptor imaging following Y-90 lanreotide therapy for carcinoid tumor: a flare response?

Journal: Clinical nuclear medicine 20050401

Title: Lanreotide treatment in a patient with interferon-associated Graves' ophthalmopathy.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050301

Title: The value of an acute octreotide suppression test in predicting long-term responses to depot somatostatin analogues in patients with active acromegaly.

Journal: Clinical endocrinology 20050301

Title: Four-year follow-up of acromegalic patients treated with the new long-acting formulation of Lanreotide (Lanreotide Autogel).

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050301

Title: [Medical treatment of acromegaly].

Journal: Annales d'endocrinologie 20050201

Title: Acromegaly due to a growth hormone-releasing hormone-secreting intracranial gangliocytoma.

Journal: Journal of endocrinological investigation 20050201

Title: Pharmacologic therapies for acromegaly: a review of their effects on glucose metabolism and insulin resistance.

Journal: Treatments in endocrinology 20050101

Title: Novel subtype specific and universal somatostatin analogues: clinical potential and pitfalls.

Journal: Current pharmaceutical design 20050101

Title: Gastrinoma of the stomach: a case report.

Journal: International journal of gastrointestinal cancer 20050101

Title: New SRIF analogs in the control of human pituitary adenomas: perspectives.

Journal: Journal of endocrinological investigation 20050101

Title: Local treatment in unresectable hepatic metastases of carcinoid tumors: Experiences with hepatic artery embolization and radiofrequency ablation.

Journal: World journal of surgical oncology 20050101

Title: [Possibilities of medical treatment in acromegaly].

Journal: Casopis lekaru ceskych 20050101

Title: BIM-23A760, a chimeric molecule directed towards somatostatin and dopamine receptors, vs universal somatostatin receptors ligands in GH-secreting pituitary adenomas partial responders to octreotide.

Journal: Journal of endocrinological investigation 20050101

Title: Pre-clinical and clinical experiences with novel somatostatin ligands: advantages, disadvantages and new prospects.

Journal: Journal of endocrinological investigation 20050101

Title: Efficacy and limits of somatostatin analogs.

Journal: Journal of endocrinological investigation 20050101

Title: Somatostatin, cortistatin, ghrelin and glucose metabolism.

Journal: Journal of endocrinological investigation 20050101

Title: Somatostatin analogs - from new molecules to new applications.

Journal: Current opinion in pharmacology 20041201

Title: Long-term response to combination therapy with estramustine and somatostatin analogue in a patient with androgen ablation-refractory prostate cancer.

Journal: Urology 20041201

Title: Long-term treatment of acromegaly with lanreotide: evidence of increased serum parathormone concentration.

Journal: Endocrine journal 20041201

Title: Somatostatin analogues and estrogens in the treatment of androgen ablation refractory prostate adenocarcinoma.

Journal: The Journal of urology 20041101

Title: Efficacy and tolerability of lanreotide Autogel therapy in acromegalic patients previously treated with octreotide LAR.

Journal: European journal of endocrinology 20040901

Title: Cabergoline addition to depot somatostatin analogues in resistant acromegalic patients: efficacy and lack of predictive value of prolactin status.

Journal: Clinical endocrinology 20040801

Title: Somatostatin and cancer: applying endocrinology to oncology.

Journal: Cancer biology & therapy 20040801

Title: Consensus report on the use of somatostatin analogs for the management of neuroendocrine tumors of the gastroenteropancreatic system.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20040601

Title: One-year follow-up of patients with acromegaly treated with fixed or titrated doses of lanreotide Autogel.

Journal: Clinical endocrinology 20040601

Title: Lanreotide autogel is a therapeutic option for patients who develop acute pancreatitis after somatostatin analog treatment.

Journal: Journal of endocrinological investigation 20040601

Title: Positive octreotide scintigraphy and determination of lanreotide activity in Paget's disease of bone associated with phosphate diabetes: a case report.

Journal: Annales d'endocrinologie 20040501

Title: Pharmacological approach to the treatment of acromegaly.

Journal: Neurosurgical focus 20040415

Title: Self-association process of a peptide in solution: from beta-sheet filaments to large embedded nanotubes.

Journal: Biophysical journal 20040401

Title: The efficacy and safety of lanreotide Autogel in patients with acromegaly previously treated with octreotide LAR.

Journal: European journal of endocrinology 20040401

Title: Octreotide long-acting repeatable and lanreotide Autogel are equally effective in controlling growth hormone secretion in acromegalic patients.

Journal: European journal of endocrinology 20040401

Title: Pharmacokinetics of a new Autogel formulation of the somatostatin analogue lanreotide after a single subcutaneous dose in healthy volunteers.

Journal: The Journal of pharmacy and pharmacology 20040401

Title: [Results of treatment with COX-2 inhibitors and lanreotide in a patient with Menetrier's hypertrophic gastropathy].

Journal: Gastroenterologie clinique et biologique 20040401

Title: Expression and function of somatostatin receptor subtype 1 in human growth hormone secreting pituitary tumors deriving from patients partially responsive or resistant to long-term treatment with somatostatin analogs.

Journal: Neuroendocrinology 20040301

Title: Novel aspects of immunosuppressive and radiotherapy management of Graves' ophthalmopathy.

Journal: Journal of endocrinological investigation 20040301

Title: Somatostatin analogs: a new tool for the management of Graves' ophthalmopathy.

Journal: Journal of endocrinological investigation 20040301

Title: Prospective, randomized, multicenter trial on the antiproliferative effect of lanreotide, interferon alfa, and their combination for therapy of metastatic neuroendocrine gastroenteropancreatic tumors.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040201

Title: Is lanreotide and/or interferon alfa an adequate therapy for neuroendocrine tumors?

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040201

Title: A single-dose comparison of the acute effects between the new somatostatin analog SOM230 and octreotide in acromegalic patients.

Journal: The Journal of clinical endocrinology and metabolism 20040201

Title: [Occurrence of carcinoid syndrome in patients with carcinoid tumors].

Journal: Vnitrni lekarstvi 20040201

Title: The role of somatostatin receptors in the medical treatment of acromegaly.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20040201

Title: Diagnostic uses of radiolabelled somatostatin receptor analogues in gastroenteropancreatic endocrine tumours.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20040201

Title: Lanreotide effect on splanchnic blood flow in healthy subjects: effect of the rate of infusion.

Journal: Clinical pharmacology and therapeutics 20040101

Title: Combination of LHRH analog with somatostatin analog and dexamethasone versus chemotherapy in hormone-refractory prostate cancer: a randomized phase II study.

Journal: Urology 20040101

Title: Acromegaly Quality of Life Questionnaire (AcroQoL).

Journal: Health and quality of life outcomes 20040101

Title: Efficacy of lanreotide 30 mg on prevention of pain relapse after oral refeeding in patients with necrotizing acute pancreatitis. A phase II prospective multicentre study.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20040101

Title: Expression of p65 gene in experimental colon cancer under the influence of 5-fluorouracil given alone and in combination with hormonal modulation.

Journal: Neoplasma 20040101

Title: Somatostatin receptors in pituitary function, diagnosis and therapy.

Journal: Frontiers of hormone research 20040101

Title: Functional activity of the multiligand analog SOM230 at human recombinant somatostatin receptor subtypes supports its usefulness in neuroendocrine tumors.

Journal: Neuroendocrinology 20040101

Title: Rapid and sustained relief from the symptoms of carcinoid syndrome: results from an open 6-month study of the 28-day prolonged-release formulation of lanreotide.

Journal: Neuroendocrinology 20040101

Title: [Use of somatulin in clinical practice].

Journal: Klinicheskaia meditsina 20040101

Title: Lanreotide Autogel for acromegaly: a new addition to the treatment armamentarium.

Journal: Treatments in endocrinology 20040101

Title: [Lanreotide in the treatment of thyroid orbitopathy].

Journal: Przeglad lekarski 20040101

Title: The role of lanreotide in the treatment of choroidal neovascularization secondary to age-related macular degeneration: a pilot clinical trial.

Journal: Retina (Philadelphia, Pa.) 20031201

Title: Somatostatin receptors in gastroentero-pancreatic neuroendocrine tumours.

Journal: Endocrine-related cancer 20031201

Title: Targeted radionuclide therapy for neuroendocrine tumours.

Journal: Endocrine-related cancer 20031201

Title: [New perspectives in diagnosis and therapy of endocrine gastroenteropancreatic (GEP) tumors with somatostatin analogues].

Journal: Minerva endocrinologica 20031201

Title: Serum leptin levels in acromegalic patients before and during somatostatin analogs therapy.

Journal: Journal of endocrinological investigation 20031201

Title: Ophthalmic complications in juvenile Graves' Disease - clinic and therapeutic approaches.

Journal: Pediatric endocrinology reviews : PER 20031201

Title: Combination therapy of ethinylestradiol and somatostatin analogue reintroduces objective clinical responses and decreases chromogranin a in patients with androgen ablation refractory prostate cancer.

Journal: The Journal of urology 20031101

Title: Lanreotide 60 mg, a new long-acting formulation: effectiveness in the chronic treatment of acromegaly.

Journal: The Journal of clinical endocrinology and metabolism 20031101

Title: Effect of propranolol and depot lanreotide SR on postprandial and circadian portal haemodynamics in cirrhosis.

Journal: Alimentary pharmacology & therapeutics 20031015

Title: Glucose homeostasis in acromegaly: effects of long-acting somatostatin analogues treatment.

Journal: Clinical endocrinology 20031001

Title: Quantitative determination of sst2 and sst5 gene expression in uterine leiomyomata and the effect of treatment with somatostatin analogue.

Journal: Fertility and sterility 20031001

Title: Effects of treatment with somatostatin analogues on the occurrence of apoptosis in somatotropinomas.

Journal: Neuro endocrinology letters 20031001

Title: The therapeutic potential of somatostatin receptor ligands in the treatment of obesity and diabetes.

Journal: Expert opinion on investigational drugs 20030901

Title: Imaging lung tumors with peptide-based radioligands.

Journal: Clinical lung cancer 20030901

Title: How effective are current therapies for acromegaly?

Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20030801

Title: Indium-111-labelled octreotide scintigraphy in the diagnosis and management of non-iodine avid metastatic carcinoma of the thyroid.

Journal: British journal of cancer 20030721

Title: Prospective, randomized, multicenter trial on the antiproliferative effect of lanreotide, interferon alfa, and their combination for therapy of metastatic neuroendocrine gastroenteropancreatic tumors--the International Lanreotide and Interferon Alfa Study Group.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030715

Title: Characterization of the intracellular mechanisms mediating somatostatin and lanreotide inhibition of DNA synthesis and growth hormone release from dispersed human GH-secreting pituitary adenoma cells in vitro.

Journal: Clinical endocrinology 20030701

Title: The treatment of sporadic versus MEN1-related pituitary adenomas.

Journal: Journal of internal medicine 20030601

Title: An in vivo OctreoScan-negative adrenal pheochromocytoma expresses somatostatin receptors and responds to somatostatin analogs treatment in vitro.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030601

Title: Evaluation of insulin resistance in acromegalic patients before and after treatment with somatostatin analogues.

Journal: Journal of endocrinological investigation 20030601

Title: Pituitary and adrenal disorders complicating pregnancy.

Journal: Current opinion in obstetrics & gynecology 20030401

Title: Preoperative lanreotide treatment for GH-secreting pituitary adenomas: effect on tumour volume and predictive factors of significant tumour shrinkage.

Journal: Clinical endocrinology 20030401

Title: Somatostatin receptors in pituitary and development of somatostatin receptor subtype-selective analogs.

Journal: Endocrine 20030401

Title: Somatostatin analogs in medical treatment of acromegaly.

Journal: Endocrine 20030401

Title: Somatostatin analogs in treatment of non-growth hormone-secreting pituitary adenomas.

Journal: Endocrine 20030401

Title: [Drug therapy prevention of pancreatic fistula after pancreaticoduodenectomy].

Journal: Annales de chirurgie 20030401

Title: [The role of somatostatin analogues in the treatment of hypophyseal adenomas].

Journal: Minerva endocrinologica 20030301

Title: The effect of the somatostatin analogue lanreotide on the prevention of urethral strictures in a rabbit model.

Journal: Urological research 20030301

Title: Clinical review 154: The role of pharmacotherapy in perioperative management of patients with acromegaly.

Journal: The Journal of clinical endocrinology and metabolism 20030301

Title: Treatment of patients with gastro-entero-pancreatic (GEP) tumours with the novel radiolabelled somatostatin analogue [177Lu-DOTA(0),Tyr3]octreotate.

Journal: European journal of nuclear medicine and molecular imaging 20030301

Title: Transformation of a MGUS to overt multiple myeloma: the possible role of a pituitary macroadenoma secreting high levels of insulin-like growth factor 1 (IGF-1).

Journal: Leukemia & lymphoma 20030301

Title: Sandostatin LAR (long-acting octreotide acetate) for malignant carcinoid syndrome: a 3-year experience.

Journal: Alimentary pharmacology & therapeutics 20030201

Title: Somatostatin receptors (sst2) are coupled to Go and modulate GTPase activity in the rabbit retina.

Journal: Journal of neurochemistry 20030201

Title: Glucagonoma syndrome: diagnosis and treatment.

Journal: Journal of the American Academy of Dermatology 20030201

Title: Perspectives of new potential therapeutic applications of somatostatin analogs.

Journal: Neuro endocrinology letters 20030101

Title: Acromegaly: a unique human headache model.

Journal: Headache 20030101

Title: Octreotide long-acting release (LAR): a review of its use in the management of acromegaly.

Journal: Drugs 20030101

Title: The role of radionuclide therapy in medullary thyroid cancer.

Journal: Tumori 20030101

Title: Distribution and functionality of the somatostatin receptor subtypes in acromegaly.

Journal: Journal of endocrinological investigation 20030101

Title: The quality of life in acromegaly.

Journal: Journal of endocrinological investigation 20030101

Title: The role of somatostatin analogs in the management of medullary thyroid carcinoma.

Journal: Journal of endocrinological investigation 20030101

Title: The use of a GH receptor antagonist in patients with acromegaly resistant to somatostatin analogs.

Journal: Journal of endocrinological investigation 20030101

Title: [Effect of lanreotide on prolactin level in patients with pituitary mixed tumors].

Journal: Annales d'endocrinologie 20021201

Title: Improvement of left ventricular hypertrophy and arrhythmias after lanreotide-induced GH and IGF-I decrease in acromegaly. A prospective multi-center study.

Journal: Journal of endocrinological investigation 20021201

Title: New approaches in targeting intracerebral tumours with 90Y-labelled radiopeptides.

Journal: European journal of nuclear medicine and molecular imaging 20021201

Title: Somatostatin receptor genes are expressed in lymphocytes from retroorbital tissues in Graves' disease.

Journal: The Journal of clinical endocrinology and metabolism 20021101

Title: Radiolabeled peptides in the diagnosis and therapy of oncological diseases.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20021101

Title: Labeling and quality control of 188Re-lanreotide.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20021101

Title: [Current treatment of carcinoid tumor].

Journal: Gastroenterologia y hepatologia 20021001

Title: Serum leptin levels in acromegaly--a significant role for adipose tissue and fasting insulin/glucose ratio.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20021001

Title: Somatostatin analogs in the treatment of medullary thyroid carcinoma.

Journal: Journal of endocrinological investigation 20021001

Title: Long-term safety and efficacy of depot long-acting somatostatin analogs for the treatment of acromegaly.

Journal: The Journal of clinical endocrinology and metabolism 20020901

Title: Short-term suppression of GH and IGF-I levels improves gonadal function and sperm parameters in men with acromegaly.

Journal: The Journal of clinical endocrinology and metabolism 20020901

Title: Use of octreotide and lanreotide in the treatment of symptomatic non-resectable carcinoid tumours.

Journal: ANZ journal of surgery 20020901

Title: Are somatostatin analogues (octreotide and lanreotide) effective in promoting healing of enterocutaneous fistulas?

Journal: Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20020901

Title: Carcinoid tumors.

Journal: Current treatment options in oncology 20020801

Title: Management of thyroid eye disease.

Journal: European journal of nuclear medicine and molecular imaging 20020801

Title: Varying additive effects of bromocriptine with two somatostatin analogs in cultures of GH-secreting adenomas.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020801

Title: Ectopic growth hormone-releasing hormone secretion by thymic carcinoid tumour.

Journal: Clinical endocrinology 20020701

Title: Somatostatin analogs in acromegaly.

Journal: The Journal of clinical endocrinology and metabolism 20020701

Title: Effects of two different somatostatin analogs on glucose tolerance in acromegaly.

Journal: Journal of endocrinological investigation 20020601

Title: Somatostatin analogues in the treatment of endocrine tumors of the gastrointestinal tract.

Journal: Expert opinion on pharmacotherapy 20020601

Title: [Novel pharmacologic therapies in acromegaly].

Journal: Orvosi hetilap 20020512

Title: Elimination of vascular fibrointimal hyperplasia by somatostatin receptor 1,4-selective agonist.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020501

Title: [Diurnal rhythm of endogenous somatostatin in patients with carcinoid].

Journal: Ceskoslovenska fysiologie 20020501

Title: Somatostatin, but not somatostatin receptor subtypes 2 and 5 selective agonists, inhibits calcitonin secretion and gene expression in the human medullary thyroid carcinoma cell line, TT.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020501

Title: The clinical role of somatostatin analogues as antineoplastic agents: much ado about nothing?

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20020501

Title: Human somatostatin receptor specificity of backbone-cyclic analogues containing novel sulfur building units.

Journal: Journal of medicinal chemistry 20020411

Title: Radiolabeled peptides in diagnosis and tumor imaging: clinical overview.

Journal: Seminars in nuclear medicine 20020401

Title: In- and Y-DOTA-lanreotide: results and implications of the MAURITIUS trial.

Journal: Seminars in nuclear medicine 20020401

Title: Somatostatins and their role in thyroid cancer.

Journal: Clinical otolaryngology and allied sciences 20020401

Title: [Regulation of cell proliferation by somatostatin].

Journal: Annales d'endocrinologie 20020401

Title: [Somatuline(R) Autogel(R), a new formulation of lanreotide for the treatment of acromegalic patients].

Journal: Annales d'endocrinologie 20020401

Title: Efficacy and safety of the new 60-mg formulation of the long-acting somatostatin analog lanreotide in the treatment of acromegaly.

Journal: Metabolism: clinical and experimental 20020301

Title: Partial tachyphylaxis to somatostatin (SST) analogues in a patient with acromegaly: the role of SST receptor desensitisation and circulating antibodies to SST analogues.

Journal: European journal of endocrinology 20020301

Title: Effect of a six-month treatment with lanreotide on cardiovascular risk factors and arterial intima-media thickness in patients with acromegaly.

Journal: European journal of endocrinology 20020301

Title: Somatostatin analogs and prednisone in advanced refractory thymic tumors.

Journal: Cancer 20020301

Title: Somatuline Autogel: an extended release lanreotide formulation.

Journal: Hospital medicine (London, England : 1998) 20020301

Title: Absence of therapeutic efficacy of the somatostatin analogue lanreotide in advanced primary hepatic cholangiocellular cancer and adenocarcinoma of the gallbladder despite in vivo somatostatin-receptor expression.

Journal: Scandinavian journal of gastroenterology 20020201

Title: Evaluation of lanreotide effects on human exocrine pancreatic secretion after a single dose: preliminary study.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20020201

Title: Efficacy of the new long-acting formulation of lanreotide (lanreotide Autogel) in the management of acromegaly.

Journal: The Journal of clinical endocrinology and metabolism 20020101

Title: Somatostatin and somatostatin analogues: diagnostic and therapeutic uses.

Journal: Current opinion in oncology 20020101

Title: Long-term effects of lanreotide SR and octreotide LAR on tumour shrinkage and GH hypersecretion in patients with previously untreated acromegaly.

Journal: Clinical endocrinology 20020101

Title: Drug design at peptide receptors: somatostatin receptor ligands.

Journal: Journal of molecular neuroscience : MN 20020101

Title: Effect of the somatostatin analogue lanreotide on meal-stimulated portal blood flow in patients with liver cirrhosis.

Journal: Digestion 20020101

Title: Treatment of malignant endocrine pancreatic tumors with a combination of alpha-interferon and somatostatin analogs.

Journal: Medical oncology (Northwood, London, England) 20020101

Title: Carcinoid tumors and syndrome.

Journal: Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20020101

Title: Carcinoid of the pancreas.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20020101

Title: Experience with indium-111 and yttrium-90-labeled somatostatin analogs.

Journal: Current pharmaceutical design 20020101

Title: Lanreotide labeled with 99mTc: preparation, preclinical testing and comparison with (111)In-DTPA-octreotide.

Journal: Anticancer research 20020101

Title: Carcinoid tumors--somatostatine in the diagnosis and therapy.

Journal: Bratislavske lekarske listy 20020101

Title: Somatostatin analogs and radiopeptides in cancer therapy.

Journal: Biopolymers 20020101

Title: Medical management of growth hormone-secreting pituitary adenomas.

Journal: Pituitary 20020101

Title: Medical management of thyrotropin-secreting pituitary adenomas.

Journal: Pituitary 20020101

Title: Current status and future opportunities for controlling acromegaly.

Journal: Pituitary 20020101

Title: Optimizing somatostatin analog therapy in acromegaly: long-acting formulations.

Journal: Treatments in endocrinology 20020101

Title: A combination therapy of dexamethasone and somatostatin analog reintroduces objective clinical responses to LHRH analog in androgen ablation-refractory prostate cancer patients.

Journal: The Journal of clinical endocrinology and metabolism 20011201

Title: [Somatostatin analogues for the treatment of gastro-entero-pancreatic neuroendocrine tumours].

Journal: Minerva endocrinologica 20011201

Title: [Lanreotide acetate may cure cystic dystrophy in heterotopic pancreas of the duodenal wall].

Journal: Gastroenterologie clinique et biologique 20011201

Title: Serum levels of tumor necrosis factor-alpha, soluble intercellular adhesion molecule-1, soluble vascular cell adhesion molecule-1, and soluble interleukin-1 receptor antagonist in patients with thyroid eye disease undergoing treatment with somatostatin analogues.

Journal: Thyroid : official journal of the American Thyroid Association 20011201

Title: Technetium-99m direct radiolabeling of lanreotide: a somatostatin analog.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20011101

Title: [Therapy of pituitary diseases. What can be achieved with medication and hormones?].

Journal: MMW Fortschritte der Medizin 20011101

Title: Effects of the somatostatin analogue octreotide on renal function in conscious diabetic rats.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20011001

Title: Effectiveness of slow-release lanreotide in previously operated and untreated patients with GH-secreting pituitary macroadenoma.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20011001

Title: [Medical treatment of digestive neuroendocrine tumours].

Journal: Minerva endocrinologica 20010901

Title: [Somatostatin and somatostatin receptors in the prostate].

Journal: Minerva endocrinologica 20010901

Title: [Somatostatin analogs in the clinical management of pituitary neoplasms].

Journal: Minerva endocrinologica 20010901

Title: Pituitary macroadenoma secreting thyrotropin and growth hormone: remission of bihormonal hypersecretion in response to lanreotide therapy.

Journal: Pituitary 20010901

Title: Decreased insulin requirements after LAR-octreotide but not after lanreotide in an acromegalic patient.

Journal: Pituitary 20010901

Title: [Estimation of efficacy of the octreotide LAR administration in the patients with somatotropinoma].

Journal: Polskie Archiwum Medycyny Wewnetrznej 20010801

Title: Effectiveness of long-acting octreotide in suppressing hormonogenesis and tumor growth in thyrotropin-secreting pituitary adenomas: report of two cases.

Journal: Pituitary 20010801

Title: A luteinizing hormone-, alpha-subunit- and prolactin-secreting pituitary adenoma responsive to somatostatin analogs: in vivo and in vitro studies.

Journal: European journal of endocrinology 20010701

Title: Somatostatin receptor-specific analogs: effects on cell proliferation and growth hormone secretion in human somatotroph tumors.

Journal: The Journal of clinical endocrinology and metabolism 20010701

Title: Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands.

Journal: European journal of nuclear medicine 20010701

Title: New trends in peptide receptor radioligands.

Journal: The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR) 20010601

Title: Effects of the somatostatin analog lanreotide on the circulating levels of chromogranin-A, prostate-specific antigen, and insulin-like growth factor-1 in advanced prostate cancer patients.

Journal: The Prostate 20010515

Title: Antitumour activity of somatostatin analogues in progressive metastatic neuroendocrine tumours.

Journal: European journal of cancer (Oxford, England : 1990) 20010501

Title: Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line tt.

Journal: The Journal of clinical endocrinology and metabolism 20010501

Title: Differential inhibition of growth hormone secretion by analogs selective for somatostatin receptor subtypes 2 and 5 in human growth-hormone-secreting adenoma cells in vitro.

Journal: Neuroendocrinology 20010501

Title: Growth hormone responses to oral glucose and intravenous thyrotropin-releasing hormone in acromegalic patients treated by slow-release lanreotide.

Journal: Journal of endocrinological investigation 20010501

Title: Pituitary gangliocytoma-adenoma presenting with acromegaly: response to treatment.

Journal: Archives of internal medicine 20010409

Title: Immunosuppressive therapy in patients with thyroid eye disease: an overview of current concepts.

Journal: European journal of endocrinology 20010401

Title: Treatment of metastatic breast cancer with somatostatin analogues--a meta-analysis.

Journal: Annals of surgical oncology 20010401

Title: Uptake of (188)Re-beta-naphthyl-peptide in cervical carcinoma tumours in athymic mice.

Journal: Nuclear medicine and biology 20010401

Title: GH/IGF-I normalization and tumor shrinkage during long-term treatment of acromegaly by lanreotide.

Journal: Journal of endocrinological investigation 20010401

Title: Administration of somatostatin analogue reduces uterine and myoma volume in women with uterine leiomyomata.

Journal: Fertility and sterility 20010301

Title: Long-term treatment of thyrotropin-secreting microadenoma with lanreotide and cabergoline.

Journal: European journal of endocrinology 20010201

Title: Somatostatin octapeptides (lanreotide, octreotide, vapreotide, and their analogs) share the growth hormone-releasing peptide receptor in the human pituitary gland.

Journal: Endocrine 20010201

Title: Dose and frequency titration of somatostatin analogues in the treatment of acromegaly - an injection of expediency?

Journal: Clinical endocrinology 20010101

Title: Cortistatin, but not somatostatin, binds to growth hormone secretagogue (GHS) receptors of human pituitary gland.

Journal: Journal of endocrinological investigation 20010101

Title: Bim-23244, a somatostatin receptor subtype 2- and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas.

Journal: The Journal of clinical endocrinology and metabolism 20010101

Title: Different response to the long-acting somatostatin analogues lanreotide and octreotide in a patient with a malignant carcinoid.

Journal: Oncology 20010101

Title: Somatostatin analogs for cancer treatment and diagnosis: an overview.

Journal: Chemotherapy 20010101

Title: Established clinical use of octreotide and lanreotide in oncology.

Journal: Chemotherapy 20010101

Title: Somatostatin analogs in oncology: a look to the future.

Journal: Chemotherapy 20010101

Title: [Therapy with somatostatin analogs in patient with orbitopathy and positive Octreoscan].

Journal: Acta medica Austriaca 20010101

Title: [Preoperative administration of a slow releasing somatostatin analog (SR-lanreotide, BIM 23014) in patients with acromegaly in the course of GH-releasing adenoma].

Journal: Neurologia i neurochirurgia polska 20010101

Title: The clinical management of neuroendocrine tumors with long-acting repeatable (LAR) octreotide: comparison with standard subcutaneous octreotide therapy.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010101

Title: Chemotherapy and biotherapy in the treatment of neuroendocrine tumours.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010101

Title: Ectopic secretion of growth hormone-releasing hormone (GHRH) in neuroendocrine tumors: relevant clinical aspects.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010101

Title: Differing effects on gall-bladder motility of lanreotide SR and octreotide LAR for treatment of acromegaly.

Journal: European journal of endocrinology 19991201

Title: Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 19991101

Title: [125I][Tyr3]octreotide labels human somatostatin sst2 and sst5 receptors.

Journal: European journal of pharmacology 19980508

Title: [125I]Tyr10-cortistatin14 labels all five somatostatin receptors.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 19980501

Title: The elucidation of somatostatin receptor functions: a current view.

Journal: Reviews of physiology, biochemistry and pharmacology 19980101

Title: Binding properties of somatostatin receptor subtypes.

Journal: Metabolism: clinical and experimental 19960801

Title: Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5).

Journal: Endocrinology 19941201

Title: Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides.

Journal: Molecular pharmacology 19930601

Title: Somatostatin cyclic octapeptide analogs which preferentially bind to SOMa receptors block a calcium current in rat superior cervical ganglion neurons.

Journal: Neuroscience letters 19890130

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Tags:127984-74-1 Molecular Formula|127984-74-1 MDL|127984-74-1 SMILES|127984-74-1 10-(4-aminobutyl)-19-[(2-amino-3-naphthalen-2-yl-propanoyl)amino]-N-(1 -carbamoyl-2-hydroxy-propyl)-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol -3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14, 17-pentazacycloicosane-4-carboxamide