Catalog No.:AA00AP68

186901-48-4 | CORTISTATIN-14

Name: Name:CORTISTATIN-14
Brand: AABLOCKS
SKU: AA00AP68
Availability: InStock
Rating: 90 (10 reviews)

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Purity

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5mg

98%

2 weeks

$604.00 $423.00

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA00AP68

Chemical Name:

CORTISTATIN-14

CAS Number:

186901-48-4

Molecular Formula:

C81H113N19O19S2

Molecular Weight:

1721.0098

MDL Number:

MFCD01075120

SMILES:

NCCCCC(C(=O)O)NC(=O)C1CSSCC(NC(=O)C2CCCN2)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(Cc2ccccc2)C(=O)NC(Cc2ccccc2)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CO)CO)Cc1ccccc1)C(O)C)CCCCN)Cc1c[nH]c2c1cccc2

Properties

Computed Properties

Complexity:

3400

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Heavy Atom Count:

121

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

-2.7

Literature

Title: De Lecea L, et al. A cortical neuropeptide with neuronal depressant and sleep-modulating properties. Nature. 1996 May 16;381(6579):242-5.

Title: Baranowska B, et al. Cortistatin and pituitary hormone secretion in rat. J Physiol Pharmacol. 2009 Mar;60(1):151-6.

Title: Braun H, et al. Protective effects of cortistatin (CST-14) against kainate-induced neurotoxicity in rat brain. Brain Res. 1998 Aug 24;803(1-2):54-60.

Title: Markovics A, et al. Comparison of the anti-inflammatory and anti-nociceptive effects of cortistatin-14 and somatostatin-14 in distinct in vitro and in vivo model systems. J Mol Neurosci. 2012 Jan;46(1):40-50.

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