Home Amines 13009-99-9
13009-99-9,MFCD00072089
Catalog No.:AA000TX8

13009-99-9 | 4-(Aminomethyl)benzenesulfonamide acetate

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100mg
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1g
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$9.00   $7.00
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5g
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$14.00   $10.00
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10g
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$23.00   $16.00
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25g
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100g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA000TX8
Chemical Name:
4-(Aminomethyl)benzenesulfonamide acetate
CAS Number:
13009-99-9
Molecular Formula:
C9H14N2O4S
Molecular Weight:
246.2835
MDL Number:
MFCD00072089
SMILES:
CC(=O)O.NCc1ccc(cc1)S(=O)(=O)N
Properties
Properties
 
BP:
382°C at 760 mmHg  
Form:
Solid  
MP:
151-152 °C  
Solubility:
DMSO: soluble1mg/mL  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
255  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  

Downstream Synthesis Route

[1]Patent:US2013/79322,2013,A1.Locationinpatent:Paragraph0051;0052

[2]Patent:US2013/90325,2013,A1.Locationinpatent:Paragraph0058;0059;0060

13009-99-9   
(4R,5S,6S)-3-(3S,5S)-N-(4-nitrobenzyloxycarbonyl)-5-(4-aminosulfonylphen-1-yl)methylcarbamoyl-3-pyrrolidinylthio-6-(R)-1-hydroxyethyl-4-methyl-7-oxo-1-azabicyclo3.2.0hept-2-ene-2-carboxylicacid(4-nitrobenzyl)methylester 

[1]Patent:US2013/79322,2013,A1

13009-99-9   
(4R,5S,6S)-3-(3S,5S)-5-(4-aminosulfonylphen-1-yl)methylcarbamoyl-3-pyrrolidinylthio-6-(R)-1-hydroxyethyl-4-methyl-7-oxo-1-azabicyclo3.2.0hept-2-ene-2-carboxylicacid 

[1]Patent:US2013/79322,2013,A1

[1]Patent:US2013/90325,2013,A1

Literature

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Silver debate continue.

Journal: Journal of wound care 20110601

Title: Comparison between topical honey and mafenide acetate in treatment of auricular burn.

Journal: American journal of otolaryngology 20110101

Title: Systemic absorption of amphotericin B with topical 5% mafenide acetate/amphotericin B solution for grafted burn wounds: is it clinically relevant?

Journal: Burns : journal of the International Society for Burn Injuries 20100201

Title: The diversity of wound presentation associated with freon contact frostbite injury.

Journal: Journal of burn care & research : official publication of the American Burn Association 20100101

Title: Understanding and managing burn pain: Part 2.

Journal: The American journal of nursing 20090501

Title: Highly antibiotic-resistant Acinetobacter baumannii clinical isolates are killed by the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG).

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20090401

Title: Comparison of therapeutic antibiotic treatments on tissue-engineered human skin substitutes.

Journal: Tissue engineering. Part A 20080501

Title: Effects of commonly used topical antimicrobial agents on Acinetobacter baumannii: an in vitro study.

Journal: Military medicine 20080101

Title: Allergic contact dermatitis to mafenide acetate: a case series and review of the literature.

Journal: Journal of drugs in dermatology : JDD 20070801

Title: Comparative evaluation of silver-containing antimicrobial dressings and drugs.

Journal: International wound journal 20070601

Title: Management of bioburden with a burn gel that targets nociceptors.

Journal: Journal of wound care 20070401

Title: Seven years' experience with Integra as a reconstructive tool.

Journal: Journal of burn care & research : official publication of the American Burn Association 20070101

Title: Controlling methicillin resistant Staphyloccocus aureus and Pseudomonas aeruginosa wound infections with a novel biomaterial.

Journal: Journal of investigative surgery : the official journal of the Academy of Surgical Research 20070101

Title: Managing extracavitary prosthetic vascular graft infections: a pathway to success.

Journal: Annals of plastic surgery 20061201

Title: Vibrational analyses of sulfamoyl halides NH2SO2X (X is F, Cl and Br).

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061001

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Topical Sulfamylon cream inhibits DNA and protein synthesis in the skin donor site wound.

Journal: Surgery 20060501

Title: Adjuvant dressing for negative pressure wound therapy in burns.

Journal: Ostomy/wound management 20060101

Title: Methylamine but not mafenide mimics insulin-like activity of the semicarbazide-sensitive amine oxidase-substrate benzylamine on glucose tolerance and on human adipocyte metabolism.

Journal: Pharmacological research 20051201

Title: Survival benefit conferred by topical antimicrobial preparations in burn patients: a historical perspective.

Journal: The Journal of trauma 20040401

Title: Comparative evaluation of topical antiseptic/antimicrobial treatment on aspects of wound repair in the porcine model.

Journal: Ostomy/wound management 20020901

Title: Using mafenide acetate in acute and chronic wounds.

Journal: Ostomy/wound management 20020901

Title: Dressings for burn injury in a military conflict--change of practice based on current evidence.

Journal: Journal of the Royal Army Medical Corps 20020901

Title: Mafenide acetate allergy presenting as recurrent chondritis.

Journal: Annals of plastic surgery 20020201

Title: Off-label drug use in WOC nursing: issues related to use of mafenide acetate to treat infected chronic wounds.

Journal: Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20010901

Title: An in vivo comparison of topical agents on wound repair.

Journal: Plastic and reconstructive surgery 20010901

Title: The use of 5% mafenide acetate solution in the postgraft treatment of necrotizing fasciitis.

Journal: The Journal of burn care & rehabilitation 20010101

Title: Does the addition of nystatin to 5% mafenide acetate and genitourinary irrigant solutions interfere with their antimicrobial activity? Assessment by two topical antimicrobial test assay systems.

Journal: The Journal of burn care & rehabilitation 20010101

Title: Topical mafenide hydrochloride aqueous spray in initial management of massive contaminated wounds with devitalized tissue.

Journal: Prehospital and disaster medicine 20010101

Title: Ashkan Afshari, et al. The Effective Duration of Antimicrobial Activity of Mafenide Acetate After Reconstitution. J Burn Care Res. 2018 Aug 17;39(5):736-738.

Title: Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324.

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Tags:13009-99-9 Molecular Formula|13009-99-9 MDL|13009-99-9 SMILES|13009-99-9 4-(Aminomethyl)benzenesulfonamide acetate