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131060-14-5,MFCD00898838
Catalog No.:AA000VDR

131060-14-5 | Nb-598

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$38.00   $26.00
- +
5mg
≥98%
in stock  
$175.00   $122.00
- +
25mg
98%
in stock  
$195.00   $136.00
- +
50mg
98%
in stock  
$328.00   $230.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA000VDR
Chemical Name:
Nb-598
CAS Number:
131060-14-5
Molecular Formula:
C27H31NOS2
Molecular Weight:
449.6711
MDL Number:
MFCD00898838
SMILES:
CCN(Cc1cccc(c1)OCc1scc(c1)c1cscc1)C/C=C/C#CC(C)(C)C
Properties

Downstream Synthesis Route

[1]Gotteland;Junquero;Oms;Delhon;Halazy[MedicinalChemistryResearch,1996,vol.6,#5,p.333-342]

[1]Gotteland;Junquero;Oms;Delhon;Halazy[MedicinalChemistryResearch,1996,vol.6,#5,p.333-342]

[1]Gotteland;Junquero;Oms;Delhon;Halazy[MedicinalChemistryResearch,1996,vol.6,#5,p.333-342]

[1]Gotteland;Junquero;Oms;Delhon;Halazy[MedicinalChemistryResearch,1996,vol.6,#5,p.333-342]

Literature

Title: Xia F, et al. Inhibition of cholesterol biosynthesis impairs insulin secretion and voltage-gated calcium channel function in pancreatic beta-cells. Endocrinology. 2008 Oct;149(10):5136-45.

Title: Horie M, et al. Effects of NB-598, a potent squalene epoxidase inhibitor, on the apical membrane uptake of cholesterol and basolateral membrane secretion of lipids in Caco-2 cells. Biochem Pharmacol. 1993 Jul 20;46(2):297-305.

Title: Horie M, et al. An inhibitor of squalene epoxidase, NB-598, suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells. Biochim Biophys Acta. 1993 May 20;1168(1):45-51.

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SDS
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Tags:131060-14-5 Molecular Formula|131060-14-5 MDL|131060-14-5 SMILES|131060-14-5 Nb-598
Catalog No.: AA000VDR
131060-14-5,MFCD00898838
131060-14-5 | Nb-598
Pack Size： 1mg
Purity： ≥98%
in stock
$38.00 $26.00
Pack Size： 5mg
Purity： ≥98%
in stock
$175.00 $122.00
Pack Size： 25mg
Purity： 98%
in stock
$195.00 $136.00
Pack Size： 50mg
Purity： 98%
in stock
$328.00 $230.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA000VDR
Chemical Name: Nb-598
CAS Number: 131060-14-5
Molecular Formula: C27H31NOS2
Molecular Weight: 449.6711
MDL Number: MFCD00898838
SMILES: CCN(Cc1cccc(c1)OCc1scc(c1)c1cscc1)C/C=C/C#CC(C)(C)C
Properties
Downstream Synthesis Route
123944-74-1    136719-34-1    131060-14-5 

[1]Gotteland;Junquero;Oms;Delhon;Halazy[MedicinalChemistryResearch,1996,vol.6,#5,p.333-342]

18791-75-8    131060-14-5 

[1]Gotteland;Junquero;Oms;Delhon;Halazy[MedicinalChemistryResearch,1996,vol.6,#5,p.333-342]

137320-59-3    131060-14-5 

[1]Gotteland;Junquero;Oms;Delhon;Halazy[MedicinalChemistryResearch,1996,vol.6,#5,p.333-342]

136719-33-0    131060-14-5 

[1]Gotteland;Junquero;Oms;Delhon;Halazy[MedicinalChemistryResearch,1996,vol.6,#5,p.333-342]

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