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155294-62-5,MFCD22665748
Catalog No.:AA00ABI5

155294-62-5 | NB-598 Maleate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
in stock  
$497.00   $348.00
- +
10mg
in stock  
$663.00   $464.00
- +
50mg
in stock  
$1,818.00   $1,273.00
- +
200mg
in stock  
$4,097.00   $2,868.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ABI5
Chemical Name:
NB-598 Maleate
CAS Number:
155294-62-5
Molecular Formula:
C31H35NO5S2
Molecular Weight:
565.7433
MDL Number:
MFCD22665748
SMILES:
OC(=O)C=CC(=O)O.CCN(Cc1cccc(c1)OCc1scc(c1)c1cscc1)CC=CC#CC(C)(C)C
Properties
Computed Properties
 
Complexity:
747  
Covalently-Bonded Unit Count:
2  
Defined Bond Stereocenter Count:
2  
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
12  

Literature

Title: Xia F, et al. Inhibition of cholesterol biosynthesis impairs secretion and voltage-gated calcium channel function in pancreatic beta-cells. Endocrinology. 2008 Oct;149(10):5136-45.

Title: Horie M, et al. Effects of NB-598, a potent squalene epoxidase inhibitor, on the apical membrane uptake of cholesterol and basolateral membrane secretion of lipids in Caco-2 cells. Biochem Pharmacol. 1993 Jul 20;46(2):297-305.

Title: Horie M, et al. An inhibitor of squalene epoxidase, NB-598, suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells. Biochim Biophys Acta. 1993 May 20;1168(1):45-51.

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