Home Pyridines 13131-02-7
13131-02-7,MFCD01859711
Catalog No.:AA009EQ0

13131-02-7 | 1-phenylpyridin-2(1H)-one

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25mg
2 weeks  
$1,898.00   $1,329.00
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125mg
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA009EQ0
Chemical Name:
1-phenylpyridin-2(1H)-one
CAS Number:
13131-02-7
Molecular Formula:
C11H9NO
Molecular Weight:
171.1953
MDL Number:
MFCD01859711
SMILES:
C1=CC=C(C=C1)N2C=CC=CC2=O
Properties
Computed Properties
 
Complexity:
249  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
1.9  

Downstream Synthesis Route

[1]ChemischeBerichte,1924,vol.57,p.1159    ZhurnalRusskagoFiziko-KhimicheskagoObshchestva,1925,vol.56,p.169

[1]ChemicalandPharmaceuticalBulletin,1985,vol.33,p.2313-2322

[1]Wang,Po-Shih;Liang,Chih-Kai;Leung,Man-Kit[Tetrahedron,2005,vol.61,#11,p.2931-2939]

[2]Panda,Niranjan;Jena,AshisKumar;Mohapatra,Sasmita;Rout,SmrutiRanjan[TetrahedronLetters,2011,vol.52,#16,p.1924-1927]

[3]Sugahara,Masakatsu;Ukita,Tatsuzo[ChemicalandPharmaceuticalBulletin,1997,vol.45,#4,p.719-721]

[4]Renger,Bernd[Synthesis,1985,#9,p.856-860]

[1]CurrentPatentAssignee:STERLINGPHARMASOLUTIONSLIMITED-US2003/236413,2003,A1Locationinpatent:Page28

[2]Sambiagio,Carlo;Munday,RachelH.;JohnBlacker;Marsden,StephenP.;McGowan,PatrickC.[RSCAdvances,2016,vol.6,#74,p.70025-70032]

[3]Wang,Po-Shih;Liang,Chih-Kai;Leung,Man-Kit[Tetrahedron,2005,vol.61,#11,p.2931-2939]

[4]Sugahara,Masakatsu;Ukita,Tatsuzo[ChemicalandPharmaceuticalBulletin,1997,vol.45,#4,p.719-721]

142-08-5    118-92-3   
isopentenzlnitrit 
  13131-02-7    4783-68-0   
5,6-benzo-2-azabarrelen-3(2H)-one 

[1]BulletinoftheChemicalSocietyofJapan,1985,vol.58,p.1149-1155

Literature

Title: Discovery and characterization of atropisomer PH-797804, a p38 MAP kinase inhibitor, as a clinical drug candidate.

Journal: ChemMedChem 20120206

Title: Design, synthesis and anti-fibrosis activity study of N₁-substituted phenylhydroquinolinone derivatives.

Journal: Molecules (Basel, Switzerland) 20120202

Title: Discovery of novel phenylpyridone derivatives as potent and selective MCH1R antagonists.

Journal: Bioorganic & medicinal chemistry 20110115

Title: Anti-inflammatory properties of a novel N-phenyl pyridinone inhibitor of p38 mitogen-activated protein kinase: preclinical-to-clinical translation.

Journal: The Journal of pharmacology and experimental therapeutics 20091201

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SDS
Tags:13131-02-7 Molecular Formula|13131-02-7 MDL|13131-02-7 SMILES|13131-02-7 1-phenylpyridin-2(1H)-one