Home Nitro Compounds 13153-27-0
13153-27-0,MFCD00005737
Catalog No.:AA000ZA1

13153-27-0 | Guanosine, 6-S-[(4-nitrophenyl)methyl]-6-thio-

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5mg
99%
1 week  
$320.00   $224.00
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10mg
99%
1 week  
$479.00   $335.00
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25mg
99%
1 week  
$908.00   $635.00
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50mg
99%
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$1,289.00   $902.00
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100mg
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$1,828.00   $1,280.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000ZA1
Chemical Name:
Guanosine, 6-S-[(4-nitrophenyl)methyl]-6-thio-
CAS Number:
13153-27-0
Molecular Formula:
C17H18N6O6S
Molecular Weight:
434.4264
MDL Number:
MFCD00005737
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(N)nc2SCc1ccc(cc1)[N+](=O)[O-]
Properties
Computed Properties
 
Complexity:
608  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
5  
XLogP3:
1.1  

Literature

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.

Journal: Bioorganic & medicinal chemistry 20080401

Title: Novel C2-purine position analogs of nitrobenzylmercaptopurine riboside as human equilibrative nucleoside transporter 1 inhibitors.

Journal: Bioorganic & medicinal chemistry 20071215

Title: Indirect activation of adenosine A1 receptors in cultured rat hippocampal neurons by volatile anaesthetics.

Journal: European journal of anaesthesiology 20050901

Title: Uptake and release of [3H]adenosine in human dental pulp.

Journal: Archives of oral biology 20030401

Title: Activation of A(3) receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons.

Journal: Restorative neurology and neuroscience 20030101

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Purine nucleoside-dependent inhibition of cellular proliferation in 1321N1 human astrocytoma cells.

Journal: The Journal of pharmacology and experimental therapeutics 20011101

Title: Turnheim K, et al. Inhibition of adenosine uptake in human erythrocytes by adenosine-5'-carboxamides, xylosyladenine, dipyridamole, hexobendine, and p-nitrobenzylthioguanosine. Biochem Pharmacol. 1978;27(18):2191-7.

Title: Parterson A, et al. Nucleoside Transport II Inhibition by p-Nitrobeazylthiogoanosine and Related Compounds. Can. J. Biochem. 49,271-274 (1971)

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Tags:13153-27-0 Molecular Formula|13153-27-0 MDL|13153-27-0 SMILES|13153-27-0 Guanosine, 6-S-[(4-nitrophenyl)methyl]-6-thio-