Home Nitro Compounds 131549-85-4
131549-85-4,MFCD08690444
Catalog No.:AA000ZBU

131549-85-4 | Benzenesulfonamide, N-(5-methyl-3-isoxazolyl)-4-nitroso-

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000ZBU
Chemical Name:
Benzenesulfonamide, N-(5-methyl-3-isoxazolyl)-4-nitroso-
CAS Number:
131549-85-4
Molecular Formula:
C10H9N3O4S
Molecular Weight:
267.2612
MDL Number:
MFCD08690444
SMILES:
O=Nc1ccc(cc1)S(=O)(=O)Nc1noc(c1)C
Properties
Computed Properties
 
Complexity:
386  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
0.9  

Literature

Title: Characterization of Drug-Specific Signaling Between Primary Human Hepatocytes and Immune Cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170701

Title: Characterization of Peroxidases Expressed in Human Antigen Presenting Cells and Analysis of the Covalent Binding of Nitroso Sulfamethoxazole to Myeloperoxidase.

Journal: Chemical research in toxicology 20150120

Title: The development of in vitro culture methods to characterize primary T-cell responses to drugs.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120501

Title: Covalent binding of nitroso-sulfonamides to glutathione S-transferase in guinea pigs with delayed type hypersensitivity.

Journal: International immunopharmacology 20120401

Title: Cutaneous drug hypersensitivity: immunological and genetic perspective.

Journal: Indian journal of dermatology 20110101

Title: Drug antigenicity, immunogenicity, and costimulatory signaling: evidence for formation of a functional antigen through immune cell metabolism.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20101201

Title: Stimulation of human T cells with sulfonamides and sulfonamide metabolites.

Journal: The Journal of allergy and clinical immunology 20100201

Title: Covalent binding of the nitroso metabolite of sulfamethoxazole is important in induction of drug-specific T-cell responses in vivo.

Journal: Molecular pharmacology 20080601

Title: Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070501

Title: Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.

Journal: Toxicology 20060501

Title: Evaluation of the clinical, immunologic, and biochemical effects of nitroso sulfamethoxazole administration to dogs: a pilot study.

Journal: Toxicology 20050301

Title: Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells.

Journal: Toxicology 20050115

Title: Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation in vivo.

Journal: British journal of pharmacology 20010501

Title: Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole-metabolite-specific human CD4+ T-cells.

Journal: British journal of pharmacology 20010201

Title: Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20000615

Title: Fine structural specificity differences of trimethoprim allergenic determinants.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 19961001

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Tags:131549-85-4 Molecular Formula|131549-85-4 MDL|131549-85-4 SMILES|131549-85-4 Benzenesulfonamide, N-(5-methyl-3-isoxazolyl)-4-nitroso-