Catalog No.:AA01ENX7

132173-06-9 | SR-31747

Name: Name:SR-31747
Brand: AABLOCKS
SKU: AA01ENX7
Rating: 90 (10 reviews)

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA01ENX7

Chemical Name:

SR-31747

CAS Number:

132173-06-9

Molecular Formula:

C23H34ClN

Molecular Weight:

359.9758

MDL Number:

MFCD00894102

SMILES:

CCN(C1CCCCC1)C/C=C\c1ccc(c(c1)Cl)C1CCCCC1

Properties

Computed Properties

Complexity:

395

Covalently-Bonded Unit Count:

Defined Bond Stereocenter Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Rotatable Bond Count:

XLogP3:

7.7

Literature

Title: Sigma receptor ligands: applications in inflammation and oncology.

Journal: Current opinion in investigational drugs (London, England : 2000) 20041101

Title: SR31747A: a peripheral sigma ligand with potent antitumor activities.

Journal: Anti-cancer drugs 20040201

Title: SR31747A is a sigma receptor ligand exhibiting antitumoural activity both in vitro and in vivo.

Journal: British journal of cancer 20030210

Title: Transcriptomic classification of antitumor agents: application to the analysis of the antitumoral effect of SR31747A.

Journal: Gene expression 20030101

Title: A DNA microarray-based approach to elucidate the effects of the immunosuppressant SR31747A on gene expression in Saccharomyces cerevisiae.

Journal: Gene expression 20020101

Title: Both the immunosuppressant SR31747 and the antiestrogen tamoxifen bind to an emopamil-insensitive site of mammalian Delta8-Delta7 sterol isomerase.

Journal: The Journal of pharmacology and experimental therapeutics 19980601

Title: Derocq JM, et al. In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the sigma ligand SR 31747. J Pharmacol Exp Ther. 1995 Jan;272(1):224-30.

Title: Silve S, et al. The immunosuppressant SR 31747 blocks cell proliferation by inhibiting a steroid isomerase in Saccharomyces cerevisiae. Mol Cell Biol. 1996 Jun;16(6):2719-27.

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Tags:132173-06-9 Molecular Formula|132173-06-9 MDL|132173-06-9 SMILES|132173-06-9 SR-31747