[1]JournalofMedicinalChemistry,1996,vol.39,p.1433-1437
[1]JournalofMedicinalChemistry,1996,vol.39,p.1433-1437
[1]JournalofMedicinalChemistry,1996,vol.39,p.1433-1437
[1]JournalofMedicinalChemistry,1996,vol.39,p.1433-1437
[1]JournalofMedicinalChemistry,1996,vol.39,p.1433-1437
Title: NO-1886 ameliorates glycogen metabolism in insulin-resistant HepG2 cells by GSK-3β signalling.
Journal: The Journal of pharmacy and pharmacology 20120201
Title: Pioglitazone-induced body weight gain is prevented by combined administration with the lipoprotein lipase activator NO-1886.
Journal: European journal of pharmacology 20111015
Title: Activation of lipoprotein lipase increases serum high density lipoprotein 2 cholesterol and enlarges high density lipoprotein 2 particles in rats.
Journal: European journal of pharmacology 20111001
Title: Ibrolipim attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway.
Journal: Die Pharmazie 20111001
Title: Hepatic gene expression profiles are altered by dietary unsalted korean fermented soybean (chongkukjang) consumption in mice with diet-induced obesity.
Journal: Journal of nutrition and metabolism 20110101
Title: Preventive effect of Ibrolipim on suppressing lipid accumulation and increasing lipoprotein lipase in the kidneys of diet-induced diabetic minipigs.
Journal: Lipids in health and disease 20110101
Title: Ibrolipim increases ABCA1/G1 expression by the LXRα signaling pathway in THP-1 macrophage-derived foam cells.
Journal: Acta pharmacologica Sinica 20101001
Title: NO-1886 suppresses diet-induced insulin resistance and cholesterol accumulation through STAT5-dependent upregulation of IGF1 and CYP7A1.
Journal: The Journal of endocrinology 20100101
Title: NO-1886 up-regulates Niemann-Pick C1 protein (NPC1) expression through liver X receptor alpha signaling pathway in THP-1 macrophage-derived foam cells.
Journal: Cardiovascular drugs and therapy 20090601
Title: Pharmacological approaches to modifying HDL: more basic science to understand HDL metabolism is necessary. Editorial to: 'NO-1886 up-regulates Niemann-Pick C1 protein (NPC1) expression through liver X receptor alpha signaling pathway in THP-1 macrophage-derived foam cells' by Xin Ma et al.
Journal: Cardiovascular drugs and therapy 20090601
Title: Evaluation of induction potency of new drug candidates on CYP1A2 and CYP3A4 using real-time one-step RT-PCR in primary cultures of cryopreserved human hepatocytes.
Journal: Drug metabolism and pharmacokinetics 20090101
Title: NO-1886, a lipoprotein lipase activator, attenuates contraction of rat intestinal ring preparations.
Journal: The journal of medical investigation : JMI 20080201
Title: Lipoprotein lipase activator ameliorates the severity of dietary steatohepatitis.
Journal: Biochemical and biophysical research communications 20070427
Title: NO-1886, a lipoprotein lipase activator, attenuates vascular smooth muscle contraction in rat aorta.
Journal: European journal of pharmacology 20070112
Title: NO-1886 upregulates ATP binding cassette transporter A1 and inhibits diet-induced atherosclerosis in Chinese Bama minipigs.
Journal: Journal of lipid research 20060901
Title: Effects of NO-1886 on inflammation-associated cytokines in high-fat/high-sucrose/high-cholesterol diet-fed miniature pigs.
Journal: European journal of pharmacology 20060701
Title: Concomitant suppression of hyperlipidemia and intestinal polyp formation by increasing lipoprotein lipase activity in Apc-deficient mice.
Journal: Biological chemistry 20060401
Title: NO-1886 (ibrolipim), a lipoprotein lipase-promoting agent, accelerates the expression of UCP3 messenger RNA and ameliorates obesity in ovariectomized rats.
Journal: Metabolism: clinical and experimental 20060201
Title: Assessment of induction of cytochrome P450 by NO-1886 (ibrolipim), a lipoprotein lipase-promoting agent, in primary cultures of human hepatocytes and in female rat liver.
Journal: Drug metabolism and pharmacokinetics 20060201
Title: Uncoupling proteins, dietary fat and the metabolic syndrome.
Journal: Nutrition & metabolism 20060101
Title: NO-1886 (ibrolipim), a lipoprotein lipase activator, increases the expression of uncoupling protein 3 in skeletal muscle and suppresses fat accumulation in high-fat diet-induced obesity in rats.
Journal: Metabolism: clinical and experimental 20051201
Title: Effects of NO-1886 (Ibrolipim), a lipoprotein lipase-promoting agent, on gene induction of cytochrome P450s, carboxylesterases, and sulfotransferases in primary cultures of human hepatocytes.
Journal: Drug metabolism and pharmacokinetics 20041201
Title: NO-1886 inhibits size of adipocytes, suppresses plasma levels of tumor necrosis factor-alpha and free fatty acids, improves glucose metabolism in high-fat/high-sucrose-fed miniature pigs.
Journal: Pharmacological research 20040301
Title: NO-1886 decreases ectopic lipid deposition and protects pancreatic beta cells in diet-induced diabetic swine.
Journal: The Journal of endocrinology 20040301
Title: Lipoprotein lipase activator NO-1886 improves fatty liver caused by high-fat feeding in streptozotocin-induced diabetic rats.
Journal: Metabolism: clinical and experimental 20040201
Title: Lipoprotein lipase activator NO-1886 (ibrolipim) accelerates the mRNA expression of fatty acid oxidation-related enzymes in rat liver.
Journal: Metabolism: clinical and experimental 20031201
Title: Pharmacokinetics and metabolism of NO-1886, a lipoprotein lipase-promoting agent, in cynomolgus monkey.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20031201
Title: Lipoprotein lipase and atherosclerosis.
Journal: Current vascular pharmacology 20030301
Title: A lipoprotein lipase-promoting agent, NO-1886, improves glucose and lipid metabolism in high fat, high sucrose-fed New Zealand white rabbits.
Journal: International journal of experimental diabesity research 20030101
Title: Lipoprotein lipase activator NO-1886.
Journal: Cardiovascular drug reviews 20030101
Title: A lipoprotein lipase activator, NO-1886 prevents impaired endothelium-dependent relaxation of aorta caused by exercise in aged rats.
Journal: Experimental gerontology 20020701
Title: Correlation between lipid and glycogen contents in liver and insulin resistance in high-fat-fed rats treated with the lipoprotein lipase activator NO-1886.
Journal: Metabolism: clinical and experimental 20020601
Title: Phosphonate O-deethylation of [4-(4-bromo-2-cyano-phenylcarbamoyl) benzyl]-phosphonic acid diethyl ester, a lipoprotein lipase-promoting agent, catalyzed by cytochrome P450 2C8 and 3A4 in human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020301
Title: Effects of the lipoprotein lipase activator NO-1886 as a suppressor agent of atherosclerosis in aorta of mild diabetic rabbits.
Journal: Arzneimittel-Forschung 20020101
Title: [Lipid-lowering drugs].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20011201
Title: Discovery of novel mesangial cell proliferation inhibitors using a three-dimensional database searching method.
Journal: Journal of medicinal chemistry 20010705
Title: Effect of lipoprotein lipase activators bezafibrate and NO-1886, on B16 melanoma-induced cachexia in mice.
Journal: Anticancer research 19990101