Title: Niclosamide induced cell apoptosis via upregulation of ATF3 and activation of PERK in Hepatocellular carcinoma cells.
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Title: Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development.
Journal: ACS medicinal chemistry letters 20131010
Title: Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice.
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Title: Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK).
Journal: Journal of medicinal chemistry 20120823
Title: Axten JM, et al. Discovery of 7-methyl-5-(1-{-(trifluoromethyl)phenylacetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo,3-dpyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulu
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