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Home Other Building Blocks 13434-13-4
13434-13-4,MFCD00058569
Catalog No.:AA007ZY4

13434-13-4 | Actinonin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥95%
in stock  
$162.00   $113.00
- +
25mg
≥95%
in stock  
$680.00   $476.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA007ZY4
Chemical Name:
Actinonin
CAS Number:
13434-13-4
Molecular Formula:
C19H35N3O5
Molecular Weight:
385.4983
MDL Number:
MFCD00058569
SMILES:
CCCCCC(C(=O)NC(C(=O)N1CCCC1CO)C(C)C)CC(=O)NO
Properties
Computed Properties
 
Complexity:
498  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
11  
Undefined Atom Stereocenter Count:
3  
XLogP3:
1.5  

Downstream Synthesis Route
aqueoussodiumperiodate 
  13434-13-4   
(2S)-2-pentylsuccinyl-L-valyl-L-prolinol 

[1]Patent:US4929633,1990,A

Literature

Title: Lee MD, et al. Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics. J Clin Invest. 2004 Oct;114(8):1107-16.

Title: Chen DZ, et al. Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor. Biochemistry. 2000 Feb 15;39(6):1256-62.

Title: Wahl, R.C., et al. Hydroxamate inhibitors of human gelatinase B (92 kDa). Bioorganic & Medicinal Chemistry Letters 5(4), 349-352 (1995).

Title: Duke SO, et al. Modes of action of microbially-produced phytotoxins. Toxins (Basel). 2011 Aug;3(8):1038-64.

Title: Kruse MN, et al. Human meprin alpha and beta homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors. Biochem J. 2004 Mar 1;378(Pt 2):383-9.

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SDS
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