[1]Levy,DanielE.;Lapierre,France;Liang,Weisheng;Ye,Wenqing;Lange,ChristopherW.;Li,Xiaoyuan;Grobelny,Damian;Casabonne,Marie;Tyrrell,David;Holme,Kevin;Nadzan,Alex;Galardy,RichardE.[JournalofMedicinalChemistry,1998,vol.41,#2,p.199-223]
[1]Davenport;Watson[TetrahedronLetters,2000,vol.41,#41,p.7983-7986]
[1]Davenport;Watson[TetrahedronLetters,2000,vol.41,#41,p.7983-7986]
[1]Davenport;Watson[TetrahedronLetters,2000,vol.41,#41,p.7983-7986]
[1]Levy,DanielE.;Lapierre,France;Liang,Weisheng;Ye,Wenqing;Lange,ChristopherW.;Li,Xiaoyuan;Grobelny,Damian;Casabonne,Marie;Tyrrell,David;Holme,Kevin;Nadzan,Alex;Galardy,RichardE.[JournalofMedicinalChemistry,1998,vol.41,#2,p.199-223]
Title: Hypoxia suppresses E-cadherin and enhances matrix metalloproteinase-2 expression favoring esophageal carcinoma migration and invasion via hypoxia inducible factor-1 alpha activation.
Journal: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20130101
Title: Epidermal growth factor receptor transactivation is required for proteinase-activated receptor-2-induced COX-2 expression in intestinal epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20120701
Title: Cell-cell and cell-matrix dynamics in intraperitoneal cancer metastasis.
Journal: Cancer metastasis reviews 20120601
Title: Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophage phagocytic activities.
Journal: The Journal of biological chemistry 20120413
Title: Matrix metalloproteinase-9 in a unique proteoglycan form in avian embryonic growth plate cartilage.
Journal: Archives of biochemistry and biophysics 20120401
Title: Changes in PSA kinetics predict metastasis- free survival in men with PSA-recurrent prostate cancer treated with nonhormonal agents: combined analysis of 4 phase II trials.
Journal: Cancer 20120315
Title: Biochemical analysis of matrix metalloproteinase activation of chemokines CCL15 and CCL23 and increased glycosaminoglycan binding of CCL16.
Journal: The Journal of biological chemistry 20120217
Title: Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections.
Journal: PLoS pathogens 20120201
Title: Labeling and enrichment of Arabidopsis thaliana matrix metalloproteases using an active-site directed, marimastat-based photoreactive probe.
Journal: Bioorganic & medicinal chemistry 20120115
Title: A network flow approach to predict drug targets from microarray data, disease genes and interactome network - case study on prostate cancer.
Journal: Journal of clinical bioinformatics 20120101
Title: Interleukin-1 stimulates ADAM17 through a mechanism independent of its cytoplasmic domain or phosphorylation at threonine 735.
Journal: PloS one 20120101
Title: Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis.
Journal: PloS one 20120101
Title: EMMPRIN/CD147 up-regulates urokinase-type plasminogen activator: implications in oral tumor progression.
Journal: BMC cancer 20120101
Title: Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer.
Journal: PloS one 20120101
Title: Matrix metalloproteinase inhibitors as investigative tools in the pathogenesis and management of vascular disease.
Journal: EXS 20120101
Title: Current knowledge on pancreatic cancer.
Journal: Frontiers in oncology 20120101
Title: Stroma targeting nuclear imaging and radiopharmaceuticals.
Journal: International journal of molecular imaging 20120101
Title: Microarray and proteomic analysis of breast cancer cell and osteoblast co-cultures: role of osteoblast matrix metalloproteinase (MMP)-13 in bone metastasis.
Journal: The Journal of biological chemistry 20110930
Title: EMMPRIN modulates epithelial barrier function through a MMP-mediated occludin cleavage: implications in dry eye disease.
Journal: The American journal of pathology 20110901
Title: Log-scale dose response of inhibitors on a chip.
Journal: Analytical chemistry 20110815
Title: An understanding of the genetic basis of asthma.
Journal: The Indian journal of medical research 20110801
Title: PI3Kinase signaling in glioblastoma.
Journal: Journal of neuro-oncology 20110701
Title: Epidermal growth factor receptor inhibition augments the expression of MHC class I and II genes.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110701
Title: Role of matrix metalloproteinases and therapeutic benefits of their inhibition in spinal cord injury.
Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20110401
Title: Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110315
Title: Targeted therapies for metastatic esophagogastric cancer.
Journal: Current treatment options in oncology 20110301
Title: EGFR gene overexpression retained in an invasive xenograft model by solid orthotopic transplantation of human glioblastoma multiforme into nude mice.
Journal: Cancer investigation 20110301
Title: Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer.
Journal: Disease models & mechanisms 20110301
Title: Extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) as a novel regulator of myogenic cell differentiation.
Journal: Journal of cellular physiology 20110101
Title: New Strategies for the Next Generation of Matrix-Metalloproteinase Inhibitors: Selectively Targeting Membrane-Anchored MMPs with Therapeutic Antibodies.
Journal: Biochemistry research international 20110101
Title: Zinc metalloproteinases and amyloid Beta-Peptide metabolism: the positive side of proteolysis in Alzheimer's disease.
Journal: Biochemistry research international 20110101
Title: Downregulation of TGF-beta receptor types II and III in oral squamous cell carcinoma and oral carcinoma-associated fibroblasts.
Journal: BMC cancer 20110101
Title: Functional biomarkers of musculoskeletal syndrome (MSS) for early in vivo screening of selective MMP-13 inhibitors.
Journal: Journal of pharmacological and toxicological methods 20110101
Title: A meta-analysis of gemcitabine containing chemotherapy for locally advanced and metastatic pancreatic adenocarcinoma.
Journal: Journal of hematology & oncology 20110101
Title: Molecular characteristics of pancreatic ductal adenocarcinoma.
Journal: Pathology research international 20110101
Title: The validation of the standard Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30 (EORTC QLQ-C30) in pre-operative patients with brain tumor in China.
Journal: BMC medical research methodology 20110101
Title: Zinc-chelation contributes to the anti-angiogenic effect of ellagic acid on inhibiting MMP-2 activity, cell migration and tube formation.
Journal: PloS one 20110101
Title: Promising molecular targeted therapies in breast cancer.
Journal: Indian journal of pharmacology 20110101
Title: Latest developments and emerging treatment options in the management of stomach cancer.
Journal: Cancer management and research 20110101
Title: HIF-1α effects on angiogenic potential in human small cell lung carcinoma.
Journal: Journal of experimental & clinical cancer research : CR 20110101
Title: Current immunotherapeutic approaches in pancreatic cancer.
Journal: Clinical & developmental immunology 20110101
Title: Long-Term Relapse-Free Survival by Interdisciplinary Collaboration in a Patient with Metastatic Pancreatic Cancer (UICC IV).
Journal: Case reports in oncology 20110101
Title: Quantitative analysis of the effect of cancer invasiveness and collagen concentration on 3D matrix remodeling.
Journal: PloS one 20110101
Title: Tumor necrosis factor α-converting enzyme inhibition reverses hepatic steatosis and improves insulin sensitivity markers and surgical outcome in mice.
Journal: PloS one 20110101
Title: Insights into the complex formed by matrix metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations.
Journal: PloS one 20110101
Title: Looking to the future: biomarkers in the management of pancreatic adenocarcinoma.
Journal: International journal of molecular sciences 20110101
Title: Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.
Journal: Clinical Medicine Insights. Oncology 20110101
Title: Mining the Active Proteome of Arabidopsis thaliana.
Journal: Frontiers in plant science 20110101
Title: A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma.
Journal: Neuro-oncology 20101101
Title: TGF-β signaling in gingival fibroblast-epithelial interaction.
Journal: Journal of dental research 20101101
Title: Novel matrix metalloproteinase inhibitor [18F]marimastat-aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancer.
Journal: Cancer research 20101001
Title: Matrix remodeling as stem cell recruitment event: a novel in vitro model for homing of human bone marrow stromal cells to the site of injury shows crucial role of extracellular collagen matrix.
Journal: Matrix biology : journal of the International Society for Matrix Biology 20101001
Title: Oligodendroglial neoplasms with ganglioglioma-like maturation: a diagnostic pitfall.
Journal: Acta neuropathologica 20100801
Title: Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma.
Journal: Neuroscience 20100630
Title: A phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours.
Journal: British journal of cancer 20100629
Title: Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer.
Journal: Journal of mammary gland biology and neoplasia 20100601
Title: A statistics-based platform for quantitative N-terminome analysis and identification of protease cleavage products.
Journal: Molecular & cellular proteomics : MCP 20100501
Title: Effects of metalloproteinase inhibition in a murine model of renal ischemia-reperfusion injury.
Journal: Pediatric research 20100301
Title: Angiogenesis: Future of pharmacological modulation.
Journal: Indian journal of pharmacology 20100201
Title: An in vitro model that can distinguish between effects on angiogenesis and on established vasculature: actions of TNP-470, marimastat and the tubulin-binding agent Ang-510.
Journal: Biochemical and biophysical research communications 20100108
Title: Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck.
Journal: Journal of biomedical science 20100101
Title: Anti-invasive and antiangiogenic effects of MMI-166 on malignant glioma cells.
Journal: BMC cancer 20100101
Title: Broad-spectrum matrix metalloproteinase inhibition curbs inflammation and liver injury but aggravates experimental liver fibrosis in mice.
Journal: PloS one 20100101
Title: Angiogenesis and progression in human melanoma.
Journal: Dermatology research and practice 20100101
Title: Current and emerging therapies for the treatment of pancreatic cancer.
Journal: OncoTargets and therapy 20100101
Title: Metalloproteinase inhibitors: status and scope from marine organisms.
Journal: Biochemistry research international 20100101
Title: Cytogenetic analysis of the pathology of frozen shoulder.
Journal: International journal of shoulder surgery 20100101
Title: The role of funding and policies on innovation in cancer drug development.
Journal: Ecancermedicalscience 20100101
Title: Metalloproteinases and their inhibitors-diagnostic and therapeutic opportunities in orthopedics.
Journal: Acta orthopaedica 20091204
Title: Integrin alpha(v)beta(3), metalloproteinases, and sphingomyelinase-2 mediate urokinase mitogenic effect.
Journal: Cellular signalling 20091201
Title: Hydroxamates: relationships between structure and plasma stability.
Journal: Journal of medicinal chemistry 20091112
Title: Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors.
Journal: The Journal of biological chemistry 20090904
Title: Two phase II trials of temozolomide with interferon-alpha2b (pegylated and non-pegylated) in patients with recurrent glioblastoma multiforme.
Journal: British journal of cancer 20090818
Title: In vivo efficacy of marimastat and chemoradiation in head and neck cancer xenografts.
Journal: ORL; journal for oto-rhino-laryngology and its related specialties 20090801
Title: Novel investigational drugs for gastric cancer.
Journal: Expert opinion on investigational drugs 20090701
Title: Matrix metalloproteinase inhibitors (MMPIs) from marine natural products: the current situation and future prospects.
Journal: Marine drugs 20090601
Title: Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.
Journal: The Biochemical journal 20090428
Title: Pharmacological treatment of a diffuse arteriovenous malformation of the upper extremity in a child.
Journal: The Journal of craniofacial surgery 20090301
Title: Matrix metalloproteinase-2 involvement in breast cancer progression: a mini-review.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20090201
Title: Current perspective of TACE inhibitors: a review.
Journal: Bioorganic & medicinal chemistry 20090115
Title: Point mutation of tyrosine 759 of the IL-6 family cytokine receptor, gp130, augments collagen-induced arthritis in DBA/1J mice.
Journal: BMC musculoskeletal disorders 20090101
Title: Long term survivors with metastatic pancreatic adenocarcinoma treated with gemcitabine: a retrospective analysis.
Journal: Journal of hematology & oncology 20090101
Title: Stereotactic radiosurgery for glioblastoma: retrospective analysis.
Journal: Radiation oncology (London, England) 20090101
Title: Risedronate inhibits human osteosarcoma cell invasion.
Journal: Journal of experimental & clinical cancer research : CR 20090101
Title: Chronic obstructive pulmonary disease: towards pharmacogenetics.
Journal: Genome medicine 20090101
Title: Temozolomide: The evidence for its therapeutic efficacy in malignant astrocytomas.
Journal: Core evidence 20090101
Title: Critical appraisal of temozolomide formulations in the treatment of primary brain tumors: patient considerations.
Journal: Cancer management and research 20090101
Title: Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer.
Journal: Journal of the National Cancer Institute 20081217
Title: Modelling prognostic factors in advanced pancreatic cancer.
Journal: British journal of cancer 20080916
Title: A critical role for matrix metalloproteinases in liver regeneration.
Journal: The Journal of surgical research 20080401
Title: Characterization of an exosite binding inhibitor of matrix metalloproteinase 13.
Journal: Protein science : a publication of the Protein Society 20080101
Title: Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas.
Journal: Cerebrospinal fluid research 20080101
Title: Experimental models of abdominal aortic aneurysms: an overview.
Journal: Current pharmaceutical design 20080101
Title: Meta-analysis of randomized trials: evaluation of benefit from gemcitabine-based combination chemotherapy applied in advanced pancreatic cancer.
Journal: BMC cancer 20080101
Title: Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains.
Journal: Journal of molecular biology 20071102
Title: Diffuse glioma growth: a guerilla war.
Journal: Acta neuropathologica 20071101
Title: Future therapeutic treatment of COPD: struggle between oxidants and cytokines.
Journal: International journal of chronic obstructive pulmonary disease 20070901
Title: MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells.
Journal: British journal of cancer 20070806
Title: Canadian recommendations for the treatment of glioblastoma multiforme.
Journal: Current oncology (Toronto, Ont.) 20070601
Title: A preclinical evaluation of pemetrexed and irinotecan combination as second-line chemotherapy in pancreatic cancer.
Journal: British journal of cancer 20070507
Title: Molecular tools for metalloprotease sub-proteome generation.
Journal: Journal of biotechnology 20070430
Title: Neutralization of the haemorrhagic activities of viperine snake venoms and venom metalloproteinases using synthetic peptide inhibitors and chelators.
Journal: Toxicon : official journal of the International Society on Toxinology 20070401
Title: Metalloelastase (MMP-12) induced inflammatory response in mice airways: effects of dexamethasone, rolipram and marimastat.
Journal: European journal of pharmacology 20070315
Title: Towards bioreductively activated prodrugs: Fe(III) complexes of hydroxamic acids and the MMP inhibitor marimastat.
Journal: Journal of inorganic biochemistry 20070301
Title: Studies of a cobalt(III) complex of the MMP inhibitor marimastat: a potential hypoxia-activated prodrug.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101
Title: Extracellular matrix metalloproteinase inducer up-regulates the urokinase-type plasminogen activator system promoting tumor cell invasion.
Journal: Cancer research 20070101
Title: High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis.
Journal: Arthritis research & therapy 20070101
Title: Impact of phase II trials with progression-free survival as end-points on survival-based phase III studies in patients with anaplastic gliomas.
Journal: BMC cancer 20070101
Title: Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study.
Journal: Arthritis research & therapy 20070101
Title: Proteinases in the joint: clinical relevance of proteinases in joint destruction.
Journal: Arthritis research & therapy 20070101
Title: Breast tumour angiogenesis.
Journal: Breast cancer research : BCR 20070101
Title: Inhibition of matrix metalloproteinases increases PPAR-alpha and IL-6 and prevents dietary-induced hepatic steatosis and injury in a murine model.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20061201
Title: Role of erlotinib in the management of pancreatic cancer.
Journal: Therapeutics and clinical risk management 20061201
Title: Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: a relationship among efficacy, joint toxicity and anticonvulsant status.
Journal: Journal of neuro-oncology 20061001
Title: Biological targets for therapeutic interventions in COPD: clinical potential.
Journal: International journal of chronic obstructive pulmonary disease 20060901
Title: Temozolomide chemotherapy in patients with recurrent malignant gliomas.
Journal: Journal of Korean medical science 20060801
Title: Randomized, double-blind, placebo-controlled trial of marimastat in glioblastoma multiforme patients following surgery and irradiation.
Journal: Journal of neuro-oncology 20060701
Title: Gastrazole (JB95008), a novel CCK2/gastrin receptor antagonist, in the treatment of advanced pancreatic cancer: results from two randomised controlled trials.
Journal: British journal of cancer 20060424
Title: Towards third generation matrix metalloproteinase inhibitors for cancer therapy.
Journal: British journal of cancer 20060410
Title: Raltitrexed-eloxatin salvage chemotherapy in gemcitabine-resistant metastatic pancreatic cancer.
Journal: British journal of cancer 20060327
Title: Anti-angiogenesis therapy in pancreatic carcinoma.
Journal: JOP : Journal of the pancreas 20060309
Title: The importance of estimating the therapeutic index in the development of matrix metalloproteinase inhibitors.
Journal: Cardiovascular research 20060215
Title: TNF-alpha as a target for anti-asthma therapy.
Journal: Clinical science (London, England : 1979) 20060201
Title: Plasma matrix metalloproteinases 7 and 9 in patients with metastatic breast cancer treated with marimastat or placebo: Eastern Cooperative Oncology Group trial E2196.
Journal: Clinical breast cancer 20060201
Title: Gastric cancer. Treatment of advanced disease and new drugs.
Journal: Frontiers in bioscience : a journal and virtual library 20050901
Title: [Role of extracellular matrix degradation enzyme for glioma invasion].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901
Title: [Inhibition of cellular adhesion and invasion in gliomas].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901
Title: [Research on the antimetastatic agents].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901
Title: [Anti-angiogenesis treatment for brain tumors--present and future].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901
Title: Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases.
Journal: Experimental cell research 20050715
Title: Marimastat in the treatment of patients with biochemically relapsed prostate cancer: a prospective randomized, double-blind, phase I/II trial.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050615
Title: The effect of marimastat, a metalloprotease inhibitor, on allergen-induced asthmatic hyper-reactivity.
Journal: Toxicology and applied pharmacology 20050601
Title: Phase I trial of the matrix metalloproteinase inhibitor marimastat combined with carboplatin and paclitaxel in patients with advanced non-small cell lung cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050501
Title: Matrix metalloproteinase inhibition impairs the processing, formation and mineralization of dental tissues during mouse molar development.
Journal: Experimental cell research 20050401
Title: Docetaxel in the management of advanced pancreatic cancer.
Journal: Seminars in oncology 20050401
Title: Analysis of combination anti-angiogenesis therapy on markers of coagulation, platelet activation and angiogenesis in patients with advanced cancer.
Journal: Cancer letters 20050310
Title: Epidermal growth factor receptor-dependent and -independent pathways in hydrogen peroxide-induced mitogen-activated protein kinase activation in cardiomyocytes and heart fibroblasts.
Journal: The Journal of pharmacology and experimental therapeutics 20050301
Title: Macrophage elastase (MMP-12): a pro-inflammatory mediator?
Journal: Memorias do Instituto Oswaldo Cruz 20050301
Title: Decreased production of collagen Type III in cultured smooth muscle cells from varicose vein patients is due to a degradation by MMPs: possible implication of MMP-3.
Journal: Journal of vascular research 20050101
Title: A matrix metalloproteinase inhibitor to treat unresectable cholangiocarcinoma.
Journal: HPB : the official journal of the International Hepato Pancreato Biliary Association 20050101
Title: ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage.
Journal: The Journal of biological chemistry 20041203
Title: Randomized phase III trial of marimastat versus placebo in patients with metastatic breast cancer who have responding or stable disease after first-line chemotherapy: Eastern Cooperative Oncology Group trial E2196.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041201
Title: Phase II trial of the antiangiogenic agent IM862 in metastatic renal cell carcinoma.
Journal: British journal of cancer 20041101
Title: Phase II study of a triplet regimen in advanced colorectal cancer using methotrexate, oxaliplatin and 5-fluorouracil.
Journal: British journal of cancer 20041018
Title: Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors. Part 3: brain tumor invasiveness.
Journal: Expert review of anticancer therapy 20041001
Title: SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells.
Journal: Cancer research 20040901
Title: Combination antiangiogenesis therapy with marimastat, captopril and fragmin in patients with advanced cancer.
Journal: British journal of cancer 20040705
Title: Zymographic detection and clinical correlations of MMP-2 and MMP-9 in breast cancer sera.
Journal: British journal of cancer 20040405
Title: Involvement of matrix metalloproteinases in the onset of dentin mineralization.
Journal: European journal of oral sciences 20040401
Title: Novel therapies for pancreatic adenocarcinoma.
Journal: Current gastroenterology reports 20040401
Title: ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma.
Journal: British journal of cancer 20040308
Title: Matrix metalloproteinase inhibitors.
Journal: Current oncology reports 20040301
Title: A phase I and pharmacological study of the matrix metalloproteinase inhibitor BB-3644 in patients with solid tumours.
Journal: British journal of cancer 20040223
Title: Crystal structure of the catalytic domain of human ADAM33.
Journal: Journal of molecular biology 20040102
Title: Recent translational research: antiangiogenic therapy for breast cancer - where do we stand?
Journal: Breast cancer research : BCR 20040101
Title: Synthesis of marimastat and a marimastat conjugate for affinity chromatography and surface plasmon resonance studies.
Journal: Bioconjugate chemistry 20040101
Title: [Expression of matrix metalloproteinases in patients with malignant tumors].
Journal: Medicina (Kaunas, Lithuania) 20040101
Title: Targeting angiogenesis: a review of angiogenesis inhibitors in the treatment of lung cancer.
Journal: Lung cancer (Amsterdam, Netherlands) 20031201
Title: Levels and molecular forms of MMP-7 (matrilysin-1) and MMP-8 (collagenase-2) in diseased human peri-implant sulcular fluid.
Journal: Journal of periodontal research 20031201
Title: Comparison of prognostic factors in patients in phase I trials of cytotoxic drugs vs new noncytotoxic agents.
Journal: British journal of cancer 20031006
Title: [Angiogenesis and metastasis in colorectal cancer].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20030901
Title: Stereospecific synthesis of 5-substituted 2-bisarylthiocyclopentane carboxylic acids as specific matrix metalloproteinase inhibitors.
Journal: Journal of medicinal chemistry 20030828
Title: Structure--activity relationships of azasugar-based MMP/ADAM inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20030818
Title: Angiogenesis inhibitors under study for the treatment of lung cancer.
Journal: Lung cancer (Amsterdam, Netherlands) 20030801
Title: A phase I and pharmacologic study of the combination of marimastat and paclitaxel in patients with advanced malignancy.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20030801
Title: Anti-angiogenesis in cancer therapy.
Journal: Seminars in oncology nursing 20030801
Title: In vitro and in vivo endochondral bone formation models allow identification of anti-angiogenic compounds.
Journal: The American journal of pathology 20030701
Title: Functional characterization of adherent synovial fluid cells in rheumatoid arthritis: destructive potential in vitro and in vivo.
Journal: Arthritis and rheumatism 20030701
Title: The interaction of metal ions and Marimastat with matrix metalloproteinase 9.
Journal: Journal of inorganic biochemistry 20030601
Title: Broad-spectrum matrix metalloproteinase inhibitor marimastat-induced musculoskeletal side effects in rats.
Journal: Arthritis and rheumatism 20030601
Title: Matrix metalloproteinases 2 and 9 (gelatinases A and B) expression in malignant mesothelioma and benign pleura.
Journal: British journal of cancer 20030519
Title: Emerging drugs for non-small cell lung cancer.
Journal: Expert opinion on emerging drugs 20030501
Title: Serum markers of matrix turnover as predictors for the evolution of colorectal cancer metastasis under chemotherapy.
Journal: British journal of cancer 20030422
Title: Marimastat may not improve survival over placebo following induction therapy for small-cell lung cancer.
Journal: Cancer treatment reviews 20030401
Title: A novel matrix metalloproteinase inhibitor, FYK-1388 suppresses tumor growth, metastasis and angiogenesis by human fibrosarcoma cell line.
Journal: International journal of oncology 20030201
Title: Rho kinase and matrix metalloproteinase inhibitors cooperate to inhibit angiogenesis and growth of human prostate cancer xenotransplants.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030201
Title: [Angiogenesis research--quo vadis?].
Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20030201
Title: Randomised double blind placebo control study of adjuvant treatment with the metalloproteinase inhibitor, Marimastat in patients with inoperable colorectal hepatic metastases: significant survival advantage in patients with musculoskeletal side-effects.
Journal: Anticancer research 20030101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20030101
Title: [Matrix metalloproteinases and atherosclerosis. Therapeutic aspects].
Journal: Annales de biologie clinique 20030101
Title: Advances in molecular therapies in patients with brain tumors.
Journal: Cancer control : journal of the Moffitt Cancer Center 20030101
Title: Drugs in development: bisphosphonates and metalloproteinase inhibitors.
Journal: Arthritis research & therapy 20030101
Title: Marimastat: BB 2516, TA 2516.
Journal: Drugs in R&D 20030101
Title: Reduced angiogenesis in peritoneal dissemination of gastric cancer through gelatinase inhibition.
Journal: Clinical & experimental metastasis 20030101
Title: Phase II study of high central dose Gamma Knife radiosurgery and marimastat in patients with recurrent malignant glioma.
Journal: International journal of radiation oncology, biology, physics 20021201
Title: Gemcitabine in the treatment of advanced pancreatic cancer: a comparative analysis of randomized trials.
Journal: Seminars in oncology 20021201
Title: Prospective, randomized, double-blind, placebo-controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group and the European Organization for Research and Treatment of Cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021115
Title: Phase II study of marimastat (BB-2516) in malignant melanoma: a clinical and tumor biopsy study of the National Cancer Institute of Canada Clinical Trials Group.
Journal: Investigational new drugs 20021101
Title: Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer.
Journal: Cancer research 20021015
Title: Matrix metalloproteinase inhibition reduces adventitial thickening and collagen accumulation following balloon dilation.
Journal: Cardiovascular research 20020901
Title: Matrix metalloproteinase inhibitor therapy to prevent complications as well as therapy for Ehler-Danlos syndrome.
Journal: Medical hypotheses 20020901
Title: A synthetic matrix metalloproteinase inhibitor prevents squamous carcinoma cell proliferation by interfering with epidermal growth factor receptor autocrine loops.
Journal: International journal of cancer 20020810
Title: Metalloproteinase inhibitor attenuates neointima formation and constrictive remodeling after angioplasty in rats: augmentative effect of alpha(v)beta(3) receptor blockade.
Journal: Atherosclerosis 20020801
Title: Matrix metalloproteinases and their role in pancreatic cancer: a review of preclinical studies and clinical trials.
Journal: Annals of surgical oncology 20020801
Title: A randomized phase II pilot trial of adjuvant marimastat in patients with early-stage breast cancer.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20020801
Title: Integrin alpha(v)beta6-associated ERK2 mediates MMP-9 secretion in colon cancer cells.
Journal: British journal of cancer 20020729
Title: A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer.
Journal: British journal of cancer 20020715
Title: Simvastatin inhibits human saphenous vein neointima formation via inhibition of smooth muscle cell proliferation and migration.
Journal: Journal of vascular surgery 20020701
Title: Matrix metalloproteinase inhibitor, marimastat, decreases peritoneal spread of gastric carcinoma in nude mice.
Journal: Japanese journal of cancer research : Gann 20020701
Title: Marimastat as maintenance therapy for patients with advanced gastric cancer: a randomised trial.
Journal: British journal of cancer 20020617
Title: Beta-aryl-succinic acid hydroxamates as dual inhibitors of matrix metalloproteinases and tumor necrosis factor alpha converting enzyme.
Journal: Journal of medicinal chemistry 20020523
Title: [New drugs in bronchial cancer].
Journal: Presse medicale (Paris, France : 1983) 20020511
Title: Design, synthesis, and characterization of potent, slow-binding inhibitors that are selective for gelatinases.
Journal: The Journal of biological chemistry 20020329
Title: Differential effects between marimastat, a TNF-alpha converting enzyme inhibitor, and anti-TNF-alpha antibody on murine models for sepsis and arthritis.
Journal: Cytokine 20020321
Title: [Progress in diagnosis and treatment of lung cancer].
Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20020320
Title: Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020301
Title: Chemokine stimulation of monocyte matrix metalloproteinase-9 requires endogenous TNF-alpha.
Journal: European journal of immunology 20020201
Title: Matrix metalloproteinases and matrix metalloproteinase inhibitors in lung cancer.
Journal: Seminars in oncology 20020201
Title: Exploiting molecular targets in pancreatic cancer.
Journal: Hematology/oncology clinics of North America 20020201
Title: Involvement of matrix metalloproteinase type-3 in hepatocyte growth factor-induced invasion of human hepatocellular carcinoma cells.
Journal: International journal of cancer 20020110
Title: Phenoxyphenyl sulfone N-formylhydroxylamines (retrohydroxamates) as potent, selective, orally bioavailable matrix metalloproteinase inhibitors.
Journal: Journal of medicinal chemistry 20020103
Title: Gastroesophageal cancer, palmar fasciitis and a matrix metalloproteinase inhibitor.
Journal: Internal medicine journal 20020101
Title: Ectodomain shedding of cystinyl aminopeptidase from human placental membranes.
Journal: Placenta 20020101
Title: Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Journal: Clinical & experimental metastasis 20020101
Title: The role of the matrix metalloproteinases during in vitro vessel formation.
Journal: Angiogenesis 20020101
Title: Angiogenesis inhibitors in the treatment of lung cancer.
Journal: Lung cancer (Amsterdam, Netherlands) 20011201
Title: A phase II trial of marimastat in advanced pancreatic cancer.
Journal: British journal of cancer 20011201
Title: Calmodulin inhibitors trigger the proteolytic processing of membrane type-1 matrix metalloproteinase, but not its shedding in glioblastoma cells.
Journal: The Biochemical journal 20011015
Title: [Tumor dormancy therapy for hepatocellular carcinoma].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20011001
Title: Marimastat therapy as adjuvant to selective embolization in skeletal metastases of differentiated thyroid carcinoma.
Journal: Clinical endocrinology 20010901
Title: Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor alpha release in vitro and in vivo.
Journal: Journal of medicinal chemistry 20010802
Title: Matrix metalloproteinase inhibition of pancreatic cancer: matching mechanism of action to clinical trial design.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010801
Title: Marimastat as first-line therapy for patients with unresectable pancreatic cancer: a randomized trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010801
Title: Expression of matrix metalloproteinases and the metastasis-associated gene S100A4 in human neuroblastoma and primitive neuroectodermal tumor cells.
Journal: Journal of pediatric surgery 20010701
Title: Arylsulphonyl hydroxamic acids: potent and selective matrix metalloproteinase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20010604
Title: [Extracellular matrix degradation enzymes: important factors in liver metastasis of colorectal cancer and good targets for anticancer metastatic therapy].
Journal: Nihon Geka Gakkai zasshi 20010501
Title: Production of MMPs in human cerebral endothelial cells and their role in shedding adhesion molecules.
Journal: Journal of neuropathology and experimental neurology 20010401
Title: [Matrix metalloproteinase in human gastric carcinoma].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010401
Title: [Matrix metalloproteinase inhibitors for therapy of cancer].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010401
Title: Alternatives to chemotherapy and radiotherapy in the treatment of small cell lung cancer.
Journal: Seminars in oncology 20010401
Title: Development of matrix metalloproteinase inhibitors in cancer therapy.
Journal: Journal of the National Cancer Institute 20010207
Title: Angiogenesis: regulators and clinical applications.
Journal: Biochemical pharmacology 20010201
Title: Oral matrix metalloproteinase inhibition and arterial remodeling after balloon dilation: an intravascular ultrasound study in the pig.
Journal: Circulation 20010116
Title: Matrix metalloproteinases in lung biology.
Journal: Respiratory research 20010101
Title: Therapeutic angiogenesis inhibitors in the treatment of cancer.
Journal: Advances in internal medicine 20010101
Title: Rasmussen HS, et al. Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat. Pharmacol Ther. 1997;75(1):69-75.
Title: Yu M, et al. Incorporation of Bulky and Cationic Cyclam-Triazole Moieties into Marimastat Can Generate Potent MMP Inhibitory Activity without Inducing Cytotoxicity. ChemistryOpen. 2013 Jun;2(3):99-105.
Title: van Wijngaarden J, et al. An in vitro model that can distinguish between effects on angiogenesis and on established vasculature: actions of TNP-470, marimastat and the tubulin-binding agent Ang-510. Biochem Biophys Res Commun. 2010 Jan 8;391(2):1161-5.
Title: Skipper JB, et al. In vivo efficacy of marimastat and chemoradiation in head and neck cancer xenografts. ORL J Otorhinolaryngol Relat Spec. 2009;71(1):1-5.
