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1356841-27-4,MFCD09841349
Catalog No.:AA009FMB

1356841-27-4 | TRANDOLAPRILAT-PHENYL-D5

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Purity
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Price(USD)
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1mg
3 weeks  
$643.00   $450.00
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10mg
3 weeks  
$3,889.00   $2,722.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009FMB
Chemical Name:
TRANDOLAPRILAT-PHENYL-D5
CAS Number:
1356841-27-4
Molecular Formula:
C22H25D5N2O5
Molecular Weight:
407.5148
MDL Number:
MFCD09841349
SMILES:
c1([2H])c(CC[C@@H](C(=O)O)N[C@H](C(=O)N2[C@H]3CCCC[C@@H]3C[C@H]2C(=O)O)C)c([2H])c(c(c1[2H])[2H])[2H]
Properties
Computed Properties
 
Complexity:
604  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
5  
Rotatable Bond Count:
8  
XLogP3:
1.2  

Literature

Title: Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril.

Journal: Biochemical pharmacology 20090401

Title: Quantification of trandolapril and its metabolite trandolaprilat in human plasma by liquid chromatography/tandem mass spectrometry using solid-phase extraction.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Protective effects of quinaprilat and trandolaprilat, active metabolites of quinapril and trandolapril, on hemolysis induced by lysophosphatidylcholine in human erythrocytes.

Journal: Biological & pharmaceutical bulletin 20030501

Title: Effects of an angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitors on burst forming units-erythroid in chronic hemodialysis patients.

Journal: American journal of nephrology 20030101

Title: Trandolaprilat, an angiotensin-converting enzyme inhibitor, is not excreted in bile via an ATP-dependent active transporter (cMOAT).

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20010501

Title: Compared properties of trandolapril, enalapril, and their diacid metabolites.

Journal: Journal of cardiovascular pharmacology 19940101

Title: Shionoiri H, et al. Trandolaprilat, an angiotensin-converting enzyme inhibitor, is not excreted in bile via an ATP-dependent active transporter (cMOAT). Hypertens Res. 2001 May;24(3):235-40.

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Tags:1356841-27-4 Molecular Formula|1356841-27-4 MDL|1356841-27-4 SMILES|1356841-27-4 TRANDOLAPRILAT-PHENYL-D5