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13609-67-1,MFCD00083364
Catalog No.:AA007MV2

13609-67-1 | Hydrocortisone 17-butyrate

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200mg
>98.0%(HPLC)
in stock  
$46.00   $32.00
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1g
>98.0%(HPLC)
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$143.00   $100.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007MV2
Chemical Name:
Hydrocortisone 17-butyrate
CAS Number:
13609-67-1
Molecular Formula:
C25H36O6
Molecular Weight:
432.5497
MDL Number:
MFCD00083364
SMILES:
CCCC(=O)OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C
Properties
Computed Properties
 
Complexity:
817  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
3.2  

Literature

Title: Allergic contact dermatitis induced by topical hydrocortisone-17-butyrate mimicking papular rosacea.

Journal: Dermatitis : contact, atopic, occupational, drug 20120101

Title: Prevalence of and factors influencing sensitization to corticosteroids in a Danish patch test population.

Journal: Contact dermatitis 20110601

Title: Effects of tacrolimus ointment on Toll-like receptors in atopic dermatitis.

Journal: Clinical and experimental dermatology 20110401

Title: Corticosteroid solubility and lipid polarity control release from solid lipid nanoparticles.

Journal: International journal of pharmaceutics 20100505

Title: Vitiligo.

Journal: The New England journal of medicine 20090423

Title: Contact allergy to topical corticosteroids--results from the IVDK and epidemiological risk assessment.

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20090101

Title: Adherence to topical hydrocortisone 17-butyrate 0.1% in different vehicles in adults with atopic dermatitis.

Journal: Journal of the American Academy of Dermatology 20090101

Title: Systematized contact dermatitis and montelukast in an atopic boy.

Journal: Pediatric dermatology 20090101

Title: Randomized controlled trial comparing the effectiveness of 308-nm excimer laser alone or in combination with topical hydrocortisone 17-butyrate cream in the treatment of vitiligo of the face and neck.

Journal: The British journal of dermatology 20081101

Title: Topical corticosteroids in the treatment of acute sunburn: a randomized, double-blind clinical trial.

Journal: Archives of dermatology 20080501

Title: Hydrocortisone butyrate 0.1% lotion in the treatment of atopic dermatitis in pediatric subjects.

Journal: Journal of drugs in dermatology : JDD 20080301

Title: [How I treat...the dry skin of the hands].

Journal: Revue medicale de Liege 20070301

Title: Corticosteroid contact allergy--the importance of late readings and testing with corticosteroids used by the patients.

Journal: Contact dermatitis 20070101

Title: Evaluation of adrenal suppression of a lipid enhanced, topical emollient cream formulation of hydrocortisone butyrate 0.1% in treating children with atopic dermatitis.

Journal: Pediatric dermatology 20070101

Title: Acquired Blaschkoid dermatitis.

Journal: Indian journal of dermatology, venereology and leprology 20070101

Title: Expression of adhesion molecules in atopic dermatitis is reduced by tacrolimus, but not by hydrocortisone butyrate: a randomized immunohistochemical study.

Journal: Clinical and experimental dermatology 20061101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: [Locoid contains citric acid].

Journal: Ugeskrift for laeger 20060313

Title: [Hydrocortisone 17-butyrate (Locoid), a thirty-year ongoing innovative drug].

Journal: Revue medicale de Liege 20060201

Title: Comparison of the efficacy and safety of 0.1% tacrolimus ointment with topical corticosteroids in adult patients with atopic dermatitis: review of randomised, double-blind clinical studies conducted in Japan.

Journal: Clinical drug investigation 20060101

Title: A multicentre, randomized, double-blind, controlled study of long-term treatment with 0.1% tacrolimus ointment in adults with moderate to severe atopic dermatitis.

Journal: The British journal of dermatology 20050601

Title: [Comparison of activity of different topical corticosteroid creams and ointments using a vasoconstriction assay: superiority of hydrocortisone butyrate over hydrocortisone].

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20050501

Title: Hydrocortisone butyrate 0.1% cream in the treatment of chronic dermatitis.

Journal: Cutis 20050201

Title: Allergic contact dermatitis from a topical corticosteroid mimicking acute generalized exanthematous pustulosis.

Journal: Acta dermato-venereologica 20050101

Title: Cushing's syndrome secondary to topical corticosteroids abuse.

Journal: Clinical endocrinology 20030601

Title: Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study.

Journal: The British journal of dermatology 20030601

Title: Nummular allergic contact dermatitis after scabies treatment.

Journal: Contact dermatitis 20030601

Title: [Hypersensitivity to hydrocortisone 17-butyrate].

Journal: Annales de dermatologie et de venereologie 20020101

Title: Targeting keratinocyte apoptosis in the treatment of atopic dermatitis and allergic contact dermatitis.

Journal: The Journal of allergy and clinical immunology 20011101

Title: A randomized, double-blind, multicenter trial comparing fluticasone propionate cream, 0.05%, and hydrocortisone-17-butyrate cream, 0.1%, applied twice daily for 4 weeks in the treatment of psoriasis.

Journal: Cutis 20010401

Title: Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids.

Journal: Archives of dermatology 19950101

Title: Langerhans cells but not monocytes are capable of antigen presentation in vitro in corticosteroid contact hypersensitivity.

Journal: The British journal of dermatology 19901201

Title: [Alclometasone dipropionate (Legederm) for the treatment of steroid-sensitive dermatoses in the elderly].

Journal: Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 19900601

Title: Domoprednate (Stermonid), a topical D-homocorticosteroid, skin atrophy and telangiectasia. A double-blind, randomized comparison with hydrocortisone butyrate, betamethasone valerate, clobetasole propionate and placebo.

Journal: Dermatologica 19850101

Title: Clinical comparison of alclometasone dipropionate cream 0.05% with hydrocortisone butyrate cream 0.1% in the treatment of atopic dermatitis in children.

Journal: The Journal of international medical research 19830101

Title: The treatment of steroid-induced rosacea and perioral dermatitis.

Journal: Dermatologica 19760101

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