[1]CurrentPatentAssignee:PFIZERINC-US5489608,1996,A
Title: Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-D-glucuronide in rat intestine and Caco-2 cells.
Journal: Archives of toxicology 20180201
Title: Xanthatin triggers Chk1-mediated DNA damage response and destabilizes Cdc25C via lysosomal degradation in lung cancer cells.
Journal: Toxicology and applied pharmacology 20171215
Title: Vibrio cholerae Cholix Toxin-Induced HepG2 Cell Death is Enhanced by Tumor Necrosis Factor-Alpha Through ROS and Intracellular Signal-Regulated Kinases.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170401
Title: Cigarette smoke extract-induced interleukin-6 expression is regulated by phospholipase D1 in human bronchial epithelial cells.
Journal: The Journal of toxicological sciences 20160201
Title: Oxidative stress parameters induced by exposure to either cadmium or 17β-estradiol on Mytilus galloprovincialis hemocytes. The role of signaling molecules.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20140101
Title: The discovery of PLK4 inhibitors: (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-ones as novel antiproliferative agents.
Journal: Journal of medicinal chemistry 20130808
Title: The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells.
Journal: Pharmacological research 20130701
Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Journal: The Biochemical journal 20130415
Title: P-cresol induces disruption of cardiomyocyte adherens junctions.
Journal: Toxicology 20130405
Title: The dynamics of PKC-induced phosphorylation triggered by Ca2+ oscillations in mouse eggs.
Journal: Journal of cellular physiology 20130101
Title: NGF upregulates the plasminogen activation inhibitor-1 in neurons via the calcineurin/NFAT pathway and the Down syndrome-related proteins DYRK1A and RCAN1 attenuate this effect.
Journal: PloS one 20130101
Title: Reversal of inhibition of putative dopaminergic neurons of the ventral tegmental area: interaction of GABA(B) and D2 receptors.
Journal: Neuroscience 20121213
Title: Cannabinoid-induced enhanced interaction and protein levels of serotonin 5-HT(2A) and dopamine D₂ receptors in rat prefrontal cortex.
Journal: Journal of psychopharmacology (Oxford, England) 20121001
Title: Novel regulation of protein kinase C-η.
Journal: Biochemical and biophysical research communications 20120907
Title: Phorbol ester-modulation of estrogenic genomic effects triggered by the environmental contaminant benzanthracene.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120901
Title: Protein kinase Cα protects against multidrug resistance in human colon cancer cells.
Journal: Molecules and cells 20120731
Title: Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells.
Journal: Oncology reports 20120601
Title: CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma.
Journal: The Journal of clinical investigation 20120601
Title: Angiotensin II plays a critical role in alcohol-induced cardiac nitrative damage, cell death, remodeling, and cardiomyopathy in a protein kinase C/nicotinamide adenine dinucleotide phosphate oxidase-dependent manner.
Journal: Journal of the American College of Cardiology 20120417
Title: Alcohol increases the permeability of airway epithelial tight junctions in Beas-2B and NHBE cells.
Journal: Alcoholism, clinical and experimental research 20120301
Title: Phosphatidylinositol 3-kinase and protein kinase D1 specifically cooperate to negatively regulate the insulin-like growth factor signaling pathway.
Journal: Biochimica et biophysica acta 20120201
Title: Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway.
Journal: British journal of pharmacology 20120101
Title: Regulation of TGFβ receptor trafficking and signaling by atypical protein kinase C.
Journal: Cellular signalling 20120101
Title: Susceptibility to natural killer cell-mediated lysis of colon cancer cells is enhanced by treatment with epidermal growth factor receptor inhibitors through UL16-binding protein-1 induction.
Journal: Cancer science 20120101
Title: High glucose-induced RhoA activation requires caveolae and PKCβ1-mediated ROS generation.
Journal: American journal of physiology. Renal physiology 20120101
Title: Neuromedin S increases L-type Ca(2+) channel currents through G(i)α-protein and phospholipase C-dependent novel protein kinase C delta pathway in adult rat ventricular myocytes.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Specific protein kinase C isoforms α and βI are involved in follicle-stimulating hormone-induced mouse follicle-enclosed oocytes meiotic resumption.
Journal: PloS one 20120101
Title: Potential role of sodium-proton exchangers in the low concentration arsenic trioxide-increased intracellular pH and cell proliferation.
Journal: PloS one 20120101
Title: A novel pathway responsible for lipopolysaccharide-induced translational regulation of TNF-α and IL-6 expression involves protein kinase C and fascin.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20111215
Title: The ERM protein, ezrin, regulates neutrophil transmigration by modulating the apical localization of MRP2 in response to the SipA effector protein during Salmonella Typhimurium infection.
Journal: Cellular microbiology 20111201
Title: Differential involvement of protein kinase C and protein kinase A in ghrelin-induced growth hormone and gonadotrophin release from goldfish (Carassius auratus) pituitary cells.
Journal: Journal of neuroendocrinology 20111201
Title: Phosphorylation of JAK2 by serotonin 5-HT (2A) receptor activates both STAT3 and ERK1/2 pathways and increases growth of JEG-3 human placental choriocarcinoma cell.
Journal: Placenta 20111201
Title: Synchronous phosphorylation of CPI-17 and MYPT1 is essential for inducing Ca(2+) sensitization in intestinal smooth muscle.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20111201
Title: Identification of small molecule inhibitors of phosphatidylinositol 3-kinase and autophagy.
Journal: The Journal of biological chemistry 20111111
Title: Central role of PKCα in isoenzyme-selective regulation of cardiac transient outward current Ito and Kv4.3 channels.
Journal: Journal of molecular and cellular cardiology 20111101
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111101
Title: Enhancement of axonal regeneration of retinal ganglion cells in adult rats by etomidate: involvement of protein kinase C.
Journal: Investigative ophthalmology & visual science 20111011
Title: ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding.
Journal: The Journal of biological chemistry 20110930
Title: Involvement of protein kinase Cdelta/extracellular signal-regulated kinase/poly(ADP-ribose) polymerase-1 (PARP-1) signaling pathway in histamine-induced up-regulation of histamine H1 receptor gene expression in HeLa cells.
Journal: The Journal of biological chemistry 20110902
Title: Zinc-triggered induction of tissue plasminogen activator by brain-derived neurotrophic factor and metalloproteinases.
Journal: Journal of neurochemistry 20110901
Title: PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells.
Journal: American journal of physiology. Heart and circulatory physiology 20110901
Title: Protein kinase C mediates peroxynitrite toxicity to oligodendrocytes.
Journal: Molecular and cellular neurosciences 20110901
Title: Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respectively.
Journal: The Journal of biological chemistry 20110826
Title: Lidocaine-induced apoptosis of gingival fibroblasts: participation of cAMP and PKC activity.
Journal: Cell biology international 20110801
Title: Signaling cascades mediate astrocyte death induced by zinc.
Journal: Toxicology letters 20110728
Title: Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKCα/ERK1/2-dependent matrix metalloproteinase-9 expression.
Journal: Toxicology letters 20110530
Title: Glycogen synthase kinase-3β is a crucial mediator of signal-induced RelB degradation.
Journal: Oncogene 20110526
Title: Protective effect of Gö6976, a PKD inhibitor, on LPS/D: -GalN-induced acute liver injury in mice.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110401
Title: Protein kinase D negatively regulates hepatitis C virus secretion through phosphorylation of oxysterol-binding protein and ceramide transfer protein.
Journal: The Journal of biological chemistry 20110401
Title: PKCα suppresses osteoblastic differentiation.
Journal: Bone 20110301
Title: Protein kinase C regulates the internalization and function of the human organic anion transporting polypeptide 1A2.
Journal: British journal of pharmacology 20110301
Title: C3b-induced eosinophil degranulation involves PI3-kinases and is inhibited by protein kinase C activity.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20110201
Title: A novel protein kinase D inhibitor attenuates early events of experimental pancreatitis in isolated rat acini.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20110101
Title: Cardiac glycosides are potent inhibitors of interferon-β gene expression.
Journal: Nature chemical biology 20110101
Title: Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat.
Journal: PloS one 20110101
Title: Protein kinase D activation stimulates the transcription of the insulin receptor gene.
Journal: Molecular and cellular endocrinology 20101215
Title: Molecular mechanisms underlying Ca2+-mediated motility of human pancreatic duct cells.
Journal: American journal of physiology. Cell physiology 20101201
Title: Chk1 inhibitor Gö6976 enhances the sensitivity of nasopharyngeal carcinoma cells to radiotherapy and chemotherapy in vitro and in vivo.
Journal: Cancer letters 20101128
Title: Protein kinase C isoforms responsible for the regulation of vascular calcium sensitivity and their relationship to integrin-linked kinase pathway after hemorrhagic shock.
Journal: The Journal of trauma 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17β-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C.
Journal: Hepatology (Baltimore, Md.) 20101001
Title: The potential use of protein kinase D inhibitors for prevention/treatment of epidermal tumors.
Journal: Journal of dermatological science 20101001
Title: Nav1.7-Ca2+ influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK) and p38 attenuate tau phosphorylation via glycogen synthase kinase-3beta: priming of Nav1.7 gating by ERK and p38.
Journal: European journal of pharmacology 20100825
Title: Identification of orally available naphthyridine protein kinase D inhibitors.
Journal: Journal of medicinal chemistry 20100812
Title: Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages.
Journal: British journal of pharmacology 20100801
Title: The effect of PKC activation and inhibition on osteogenic differentiation of human mesenchymal stem cells.
Journal: Journal of tissue engineering and regenerative medicine 20100701
Title: Chitinase induce the release of IL-8 in human airway epithelial cells, via Ca2+-dependent PKC and ERK pathways.
Journal: Scandinavian journal of immunology 20100701
Title: Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms.
Journal: Biochemical pharmacology 20100615
Title: RNAi-mediated knockdown of protein kinase C-alpha inhibits cell migration in MM-RU human metastatic melanoma cell line.
Journal: Melanoma research 20100601
Title: Up-regulation of cyclin D1 expression in asthma serum-sensitized human airway smooth muscle promotes proliferation via protein kinase C alpha.
Journal: Experimental lung research 20100501
Title: The effect of protein kinase C and G protein-coupled receptor kinase inhibition on tolerance induced by mu-opioid agonists of different efficacy.
Journal: The Journal of pharmacology and experimental therapeutics 20100301
Title: Angiotensin II inhibits activity of human organic anion transporter 3 through activation of protein kinase Calpha: accelerating endocytosis of the transporter.
Journal: European journal of pharmacology 20100210
Title: Involvement of phosphatidylcholine-phospholipase C and protein kinase C in peptidoglycan-induced nuclear factor-kappaB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages.
Journal: Pharmacological research 20100201
Title: Caveolin-1 promotes resistance to chemotherapy-induced apoptosis in Ewing's sarcoma cells by modulating PKCalpha phosphorylation.
Journal: International journal of cancer 20100115
Title: Interactive role of protein phosphatase 2A and protein kinase Calpha in the stretch-induced triphosphorylation of myosin light chain in canine cerebral artery.
Journal: Journal of vascular research 20100101
Title: Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation.
Journal: Neurobiology of disease 20100101
Title: Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway.
Journal: Molecular pharmacology 20100101
Title: A novel, nongenomic mechanism underlies retinoic acid-induced growth cone turning.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091111
Title: An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation.
Journal: PLoS biology 20091101
Title: Mechanoregulation of BK channel activity in the mammalian cortical collecting duct: role of protein kinases A and C.
Journal: American journal of physiology. Renal physiology 20091001
Title: Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and gamma-adducin.
Journal: International journal of oncology 20091001
Title: Signal transducer and activator of transcription 3 (STAT3) regulates adipocyte differentiation via peroxisome-proliferator-activated receptor gamma (PPARgamma).
Journal: Biology of the cell 20090923
Title: A(1) adenosine receptor-mediated PKC and p42/p44 MAPK signaling in mouse coronary artery smooth muscle cells.
Journal: American journal of physiology. Heart and circulatory physiology 20090901
Title: Involvement of protein kinase C in IL-1beta-induced expression of cyclooxygenase-2 in human gingival fibroblasts.
Journal: Journal of oral science 20090901
Title: Fates of neurotrophins after retrograde axonal transport: phosphorylation of p75NTR is a sorting signal for delayed degradation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090826
Title: Mechanisms of nuclear vitamin D receptor resistance in Harvey-ras-transfected cells.
Journal: The Journal of nutritional biochemistry 20090801
Title: Knockout of the predominant conventional PKC isoform, PKCalpha, in mouse skeletal muscle does not affect contraction-stimulated glucose uptake.
Journal: American journal of physiology. Endocrinology and metabolism 20090801
Title: Rottlerin protected dopaminergic cell line from cytotoxicity of 6-hydroxydopamine by inhibiting PKCdelta phosphorylation.
Journal: Neuroscience bulletin 20090801
Title: Tamoxifen inhibits tumor cell invasion and metastasis in mouse melanoma through suppression of PKC/MEK/ERK and PKC/PI3K/Akt pathways.
Journal: Experimental cell research 20090715
Title: Effects of phorbol ester-sensitive PKC (c/nPKC) activation on the production of adiponectin in 3T3-L1 adipocytes.
Journal: IUBMB life 20090601
Title: Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells.
Journal: Toxicology and applied pharmacology 20090515
Title: Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.
Journal: Cancer research 20090501
Title: Regulation of secretases by all-trans-retinoic acid.
Journal: The FEBS journal 20090501
Title: ADAM-10-mediated N-cadherin cleavage is protein kinase C-alpha dependent and promotes glioblastoma cell migration.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090408
Title: p66Shc links alpha1-adrenergic receptors to a reactive oxygen species-dependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes.
Journal: Circulation research 20090313
Title: Inhibition of CHK1 kinase by Gö6976 converts 8-chloro-adenosine-induced G2/M arrest into S arrest in human myelocytic leukemia K562 cells.
Journal: Biochemical pharmacology 20090301
Title: Alpha-adrenergic signalling activates protein kinase D and causes nuclear efflux of the transcriptional repressor HDAC5 in cultured adult mouse soleus skeletal muscle fibres.
Journal: The Journal of physiology 20090301
Title: Lead acetate induces EGFR activation upstream of SFK and PKCalpha linkage to the Ras/Raf-1/ERK signaling.
Journal: Toxicology and applied pharmacology 20090301
Title: Improvement of deficient natural killer activity and delayed bactericidal activity by a thiol proteinase inhibitor, E-64-d, in leukocytes from Chediak-Higashi syndrome patients in vitro.
Journal: International immunopharmacology 20090301
Title: Regulation of human organic anion transporter 1 by ANG II: involvement of protein kinase Calpha.
Journal: American journal of physiology. Endocrinology and metabolism 20090201
Title: Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling.
Journal: Brain : a journal of neurology 20090201
Title: Bone morphogenic protein 2 activates protein kinase D to regulate histone deacetylase 7 localization and repression of Runx2.
Journal: The Journal of biological chemistry 20090123
Title: Protein kinase D1 autophosphorylation via distinct mechanisms at Ser744/Ser748 and Ser916.
Journal: The Journal of biological chemistry 20090123
Title: PCPH/ENTPD5 expression confers to prostate cancer cells resistance against cisplatin-induced apoptosis through protein kinase Calpha-mediated Bcl-2 stabilization.
Journal: Cancer research 20090101
Title: Agonist-induced nuclear export of GFP-HDAC5 in isolated adult rat ventricular myocytes.
Journal: Journal of pharmacological and toxicological methods 20090101
Title: CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors.
Journal: Molecular cancer 20090101
Title: Protein kinase Cmu plays an essential role in hypertonicity-induced heat shock protein 70 expression.
Journal: Experimental & molecular medicine 20081231
Title: Phosphorylation of TRPV1 by neurokinin-1 receptor agonist exaggerates the capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons.
Journal: Neuropharmacology 20081201
Title: Ca(2+)-dependent protein kinase C isoforms are critical to estradiol 17beta-D-glucuronide-induced cholestasis in the rat.
Journal: Hepatology (Baltimore, Md.) 20081201
Title: The relaxant effect of okadaic acid on canine basilar artery involves activation of PKCalpha and phosphorylation of the myosin light chain at Thr-9.
Journal: European journal of pharmacology 20081119
Title: Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20081001
Title: Novel PKC signaling is required for LPS-induced soluble Flt-1 expression in macrophages.
Journal: Journal of leukocyte biology 20080901
Title: Protein kinase C inhibitor Gö6976 augments caffeine-induced reversal of chemoresistance to cis-diamminedichloroplatinum-II (CDDP) in a human ovarian cancer model.
Journal: Gynecologic oncology 20080901
Title: TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCalpha-ezrin pathway.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080801
Title: Phospholipase C/protein kinase C pathway mediates angiotensin II-dependent apoptosis in neonatal rat cardiac fibroblasts expressing AT1 receptor.
Journal: Journal of cardiovascular pharmacology 20080801
Title: Small-molecule activation of neuronal cell fate.
Journal: Nature chemical biology 20080701
Title: Heme oxygenase-1 mediates the anti-inflammatory effect of Curcumin within LPS-stimulated human monocytes.
Journal: Journal of cellular physiology 20080601
Title: Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts.
Journal: American journal of physiology. Cell physiology 20080601
Title: Coordinated phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 and protein kinase C betaII in the diabetic fat tissue.
Journal: American journal of physiology. Endocrinology and metabolism 20080601
Title: Protein kinase C protects from DNA damage-induced necrotic cell death by inhibiting poly(ADP-ribose) polymerase-1.
Journal: FEBS letters 20080528
Title: Protein kinase C alpha promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor.
Journal: Cardiovascular research 20080501
Title: Inhibitory role of TGIF in the As2O3-regulated p21 WAF1/CIP1 expression.
Journal: Journal of biomedical science 20080501
Title: Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501
Title: Endothelial PKC delta activation attenuates neutrophil transendothelial migration.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080501
Title: Protein kinase C inhibitors alter neurotensin receptor binding and function in prostate cancer PC3 cells.
Journal: Regulatory peptides 20080410
Title: TGF-beta mediates PTEN suppression and cell motility through calcium-dependent PKC-alpha activation in pancreatic cancer cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20080401
Title: Essential role of PKCdelta in histone deacetylase inhibitor-induced Epstein-Barr virus reactivation in nasopharyngeal carcinoma cells.
Journal: The Journal of general virology 20080401
Title: P70 S6 kinase negatively regulates fibroblast growth factor 2-stimulated interleukin-6 synthesis in osteoblasts: function at a point downstream from protein kinase C.
Journal: The Journal of endocrinology 20080401
Title: Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure.
Journal: Circulation research 20080328
Title: Probable involvement of epsilon-isoform of protein kinase C in rat bronchial smooth muscle contraction induced by acetylcholine.
Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20080201
Title: Inhibitors of protein kinase C sensitise multiple myeloma cells to common genotoxic drugs.
Journal: European journal of haematology 20080101
Title: Pot1 and cell cycle progression cooperate in telomere length regulation.
Journal: Nature structural & molecular biology 20080101
Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20071218
Title: The selectivity of protein kinase inhibitors: a further update.
Journal: The Biochemical journal 20071215
Title: Activation of bone morphogenetic protein signaling by a Gemini vitamin D3 analogue is mediated by Ras/protein kinase C alpha.
Journal: Cancer research 20071215
Title: Rottlerin causes pulmonary edema in vivo: a possible role for PKCdelta.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20071201
Title: Activation of protein kinase D1 in mast cells in response to innate, adaptive, and growth factor signals.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20071201
Title: nPKCepsilon, a P2Y2-R downstream effector in regulated mucin secretion from airway goblet cells.
Journal: American journal of physiology. Cell physiology 20071101
Title: Induction of death receptor 5 and suppression of survivin contribute to sensitization of TRAIL-induced cytotoxicity by quercetin in non-small cell lung cancer cells.
Journal: Carcinogenesis 20071001
Title: Mitochondrial anchoring of PKCalpha by PICK1 confers resistance to etoposide-induced apoptosis.
Journal: Apoptosis : an international journal on programmed cell death 20071001
Title: Mild in vitro trauma induces rapid Glur2 endocytosis, robustly augments calcium permeability and enhances susceptibility to secondary excitotoxic insult in cultured Purkinje cells.
Journal: Brain : a journal of neurology 20071001
Title: Impaired gap junction formation and intercellular calcium signaling in urinary bladder cancer cells can be improved by Gö6976.
Journal: Cell communication & adhesion 20071001
Title: The anti-inflammatory activity of Phellinus linteus (Berk. & M.A. Curt.) is mediated through the PKCdelta/Nrf2/ARE signaling to up-regulation of heme oxygenase-1.
Journal: Journal of ethnopharmacology 20070905
Title: Protein kinase C-beta and -delta isoenzymes promote arachidonic acid production and proliferation of MonoMac-6 cells.
Journal: Journal of molecular medicine (Berlin, Germany) 20070901
Title: Prevention of TGF-beta-induced apoptosis by interlukin-4 through Akt activation and p70S6K survival signaling pathways.
Journal: Apoptosis : an international journal on programmed cell death 20070901
Title: The role of protein kinase C isoenzymes in the regulation of calcineurin activity in human peripheral blood mononuclear cells.
Journal: International journal of molecular medicine 20070901
Title: Protein kinase C-dependent antilipolysis by insulin in rat adipocytes.
Journal: Biochimica et biophysica acta 20070901
Title: PKC inhibitor Go6976 induces mitosis and enhances doxorubicin-paclitaxel cytotoxicity in urinary bladder carcinoma cells.
Journal: Cancer letters 20070808
Title: Mechanism of membrane redistribution of protein kinase C by its ATP-competitive inhibitors.
Journal: The Biochemical journal 20070715
Title: Role of L-type calcium channels and PKC in active tone development in rabbit coronary artery.
Journal: American journal of physiology. Heart and circulatory physiology 20070601
Title: G(alpha)q-mediated regulation of TASK3 two-pore domain potassium channels: the role of protein kinase C.
Journal: Molecular pharmacology 20070601
Title: Protein kinase Calpha determines HER2 fate in breast carcinoma cells with HER2 protein overexpression without gene amplification.
Journal: Cancer research 20070601
Title: Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII.
Journal: The Journal of biological chemistry 20070518
Title: Involvement of nPKC-MAPK pathway in the decrease of nucleophosmin/B23 during megakaryocytic differentiation of human myelogenous leukemia K562 cells.
Journal: Life sciences 20070508
Title: Lactosylceramide alpha2,3-sialyltransferase is induced via a PKC/ERK/CREB-dependent pathway in K562 human leukemia cells.
Journal: Molecules and cells 20070430
Title: Activation of protein kinase C and disruption of endothelial monolayer integrity by sodium arsenite--Potential mechanism in the development of atherosclerosis.
Journal: Toxicology and applied pharmacology 20070415
Title: Regulation of anion exchanger Slc26a6 by protein kinase C.
Journal: American journal of physiology. Cell physiology 20070401
Title: Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells.
Journal: American journal of physiology. Cell physiology 20070401
Title: The autocrine TNFalpha signalling loop in keratinocytes requires atypical PKC species and NF-kappaB activation but is independent of cholesterol-enriched membrane microdomains.
Journal: Biochemical pharmacology 20070215
Title: A nerve growth factor-induced retrograde survival signal mediated by mechanisms downstream of TrkA.
Journal: Neuropharmacology 20070201
Title: Distribution of phosphorylated protein kinase C alpha in goldfish retinal bipolar synaptic terminals: control by state of adaptation and pharmacological treatment.
Journal: Cell and tissue research 20070201
Title: Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role.
Journal: Journal of leukocyte biology 20070201
Title: Protein kinase C activation increases endothelial nitric oxide release in mesenteric arteries from orchidectomized rats.
Journal: The Journal of endocrinology 20070101
Title: Activation-induced upregulation of inhibitory killer Ig-like receptors is regulated by protein kinase C.
Journal: Immunology and cell biology 20070101
Title: Lactoferrin stimulates erythrocyte Na+/K+ -adenosine triphosphatase: effect of some modulators of membrane phosphorylation.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101
Title: SDF-1-induced adhesion of monocytes to vascular endothelium is modulated by azelnidipine via protein kinase C inhibition.
Journal: European journal of pharmacology 20061215
Title: Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.
Journal: Journal of medicinal chemistry 20061214
Title: [Phosphorylation of PKCdelta participates in the toxicity of 6-hydroxydopamine on dopaminergic neuroblastoma cell].
Journal: Zhonghua yi xue za zhi 20061205
Title: PAR-1-dependent pp60src activation is dependent on protein kinase C and increased [Ca2+]: evidence that pp60src does not regulate PAR-1-dependent Ca2+ entry in human platelets.
Journal: Journal of thrombosis and haemostasis : JTH 20061201
Title: Munc18-1 phosphorylation by protein kinase C potentiates vesicle pool replenishment in bovine chromaffin cells.
Journal: Neuroscience 20061201
Title: Beta-1, 3-glucan modulates PKC signalling in Lymnaea stagnalis defence cells: a role for PKC in H2O2 production and downstream ERK activation.
Journal: The Journal of experimental biology 20061201
Title: Corticotropin-releasing hormone inhibits progesterone production in cultured human placental trophoblasts.
Journal: Journal of molecular endocrinology 20061201
Title: Gö6976 is a potent inhibitor of the JAK 2 and FLT3 tyrosine kinases with significant activity in primary acute myeloid leukaemia cells.
Journal: British journal of haematology 20061101
Title: VCAM-1 signals activate endothelial cell protein kinase Calpha via oxidation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20061101
Title: Protein kinase Cbeta isoform down-regulates the expression of MDR3 P-glycoprotein in human Chang liver cells.
Journal: Biochimica et biophysica acta 20061001
Title: Modulation of mitochondrial metabolic function by phorbol 12-myristate 13-acetate through increased mitochondrial translocation of protein kinase Calpha in C2C12 myocytes.
Journal: Biochemical pharmacology 20060928
Title: Superoxide stimulates NaCl absorption in the thick ascending limb via activation of protein kinase C.
Journal: Hypertension (Dallas, Tex. : 1979) 20060901
Title: The sarcoplasmic-endoplasmic reticulum Ca2+ ATPase 2b regulates the Ca2+ transients elicited by P2Y2 activation in PC Cl3 thyroid cells.
Journal: The Journal of endocrinology 20060901
Title: Activation of the extracellular calcium-sensing receptor initiates insulin secretion from human islets of Langerhans: involvement of protein kinases.
Journal: The Journal of endocrinology 20060901
Title: Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks.
Journal: Purinergic signalling 20060901
Title: Oxidative stress induces actin-cytoskeletal and tight-junctional alterations in hepatocytes by a Ca2+ -dependent, PKC-mediated mechanism: protective effect of PKA.
Journal: Free radical biology & medicine 20060601
Title: Proinsulin C-peptide stimulates a PKC/IkappaB/NF-kappaB signaling pathway to activate COX-2 gene transcription in Swiss 3T3 fibroblasts.
Journal: Journal of biochemistry 20060601
Title: Protein kinase C theta co-operates with calcineurin in the activation of slow muscle genes in cultured myogenic cells.
Journal: Journal of cellular physiology 20060501
Title: Lysophosphatidic acid-induced changes in cAMP profiles in young and senescent human fibroblasts as a clue to the ageing process.
Journal: Mechanisms of ageing and development 20060501
Title: Regulation of IL-1-induced selective IL-6 release from human mast cells and inhibition by quercetin.
Journal: British journal of pharmacology 20060501
Title: Effect of protein kinase C inhibitors on porcine oocyte activation.
Journal: Journal of experimental zoology. Part A, Comparative experimental biology 20060401
Title: Bradykinin augments EGF-induced airway smooth muscle proliferation by activation of conventional protein kinase C isoenzymes.
Journal: European journal of pharmacology 20060327
Title: Regulation of homocysteine-induced MMP-9 by ERK1/2 pathway.
Journal: American journal of physiology. Cell physiology 20060301
Title: Calcium signaling stimulates translation of HIF-alpha during hypoxia.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Title: Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways.
Journal: Journal of cellular biochemistry 20060201
Title: Assembly of tight junction is regulated by the antagonism of conventional and novel protein kinase C isoforms.
Journal: The international journal of biochemistry & cell biology 20060201
Title: Regulation of skin microvasculature angiogenesis, cell migration, and permeability by a specific inhibitor of PKCalpha.
Journal: The Journal of investigative dermatology 20060201
Title: High glucose exacerbates neutrophil adhesion to human retinal endothelial cells.
Journal: Experimental eye research 20060101
Title: Regulation of CD93 cell surface expression by protein kinase C isoenzymes.
Journal: Microbiology and immunology 20060101
Title: Effect of PKC isozyme inhibition on forskolin-induced activation of BKCa channels in rat pulmonary arterial smooth muscle.
Journal: Lung 20060101
Title: Different roles of protein kinase C-betaI and -delta in the regulation of adipocyte differentiation.
Journal: The international journal of biochemistry & cell biology 20060101
Title: PKCdelta mediates testosterone-induced increases in coronary smooth muscle Cav1.2.
Journal: The Journal of biological chemistry 20051230
Title: Opposing effects of phorbol-12-myristate-13-acetate, an activator of protein kinase C, on the signaling of structurally related human dopamine D1 and D5 receptors.
Journal: Journal of neurochemistry 20051201
Title: Suppression of protein kinase Cepsilon mediates 17beta-estradiol-induced neuroprotection in an immortalized hippocampal cell line.
Journal: Journal of neurochemistry 20051101
Title: TGF-beta1 induces cardiac hypertrophic responses via PKC-dependent ATF-2 activation.
Journal: Journal of molecular and cellular cardiology 20051001
Title: Hyposmolarity evokes norepinephrine efflux from synaptosomes by a depolarization- and Ca2+ -dependent exocytotic mechanism.
Journal: The European journal of neuroscience 20051001
Title: Immunomodulatory drugs (IMiDs) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kappaB, OCT-1, or NF-AT.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20051001
Title: PKCdelta mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCdelta in vascular hypertrophy.
Journal: The Biochemical journal 20050915
Title: RACK1 mediates activation of JNK by protein kinase C [corrected].
Journal: Molecular cell 20050805
Title: Involvement of protein kinase C in the mechanism of action of Escherichia coli heat-stable enterotoxin (STa) in a human colonic carcinoma cell line, COLO-205.
Journal: Toxicology and applied pharmacology 20050801
Title: A novel protein kinase C alpha-dependent signal to ERK1/2 activated by alphaVbeta3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells.
Journal: Journal of cell science 20050801
Title: [The nuclear factor kappa B activation: the key step of cell proliferation in estrogen receptor-negative breast cancer cells].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20050801
Title: Effect of protein kinase C activation on intracellular Ca2+ signaling and integrity of intestinal epithelial cells.
Journal: European journal of pharmacology 20050725
Title: Cigarette smoke extract increases C5a receptor expression in human bronchial epithelial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20050701
Title: PKC delta-induced activation of MAPK pathway is required for bFGF-stimulated proliferation of coronary smooth muscle cells.
Journal: Cardiovascular research 20050701
Title: PKC-alpha-mediated remodeling of the actin cytoskeleton is involved in constitutive albumin uptake by proximal tubule cells.
Journal: American journal of physiology. Renal physiology 20050601
Title: Protein kinase C-alpha mediates TNF release process in RBL-2H3 mast cells.
Journal: British journal of pharmacology 20050601
Title: A comparison of the roles of protein kinase C in long-term potentiation in rat hippocampal areas CA1 and CA3.
Journal: Cellular and molecular neurobiology 20050601
Title: Transcriptional profiling of gamma delta T cells identifies a role for vitamin D in the immunoregulation of the V gamma 9V delta 2 response to phosphate-containing ligands.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050515
Title: Isoflurane induces a protein kinase C alpha-dependent increase in cell-surface protein level and activity of glutamate transporter type 3.
Journal: Molecular pharmacology 20050501
Title: Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050501
Title: Malondialdehyde-acetaldehyde adducts decrease bronchial epithelial wound repair.
Journal: Alcohol (Fayetteville, N.Y.) 20050501
Title: Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2.
Journal: Biochemical and biophysical research communications 20050401
Title: Gefitinib ('Iressa', ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells.
Journal: Cancer chemotherapy and pharmacology 20050401
Title: Antecedent ethanol ingestion prevents postischemic leukocyte adhesion and P-selectin expression by a protein kinase C-dependent mechanism.
Journal: Digestive diseases and sciences 20050401
Title: Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity.
Journal: The Journal of clinical investigation 20050301
Title: Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium.
Journal: The Journal of experimental biology 20050301
Title: The role of protein kinase C in regulating equine eosinophil adherence and superoxide production.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050301
Title: Protein kinase C modulates agonist-sensitive release of Ca2+ from internal stores in HEK293 cells overexpressing the calcium sensing receptor.
Journal: The Journal of biological chemistry 20050211
Title: Role of Chk1 and Chk2 in Ara-C-induced differentiation of human leukemia K562 cells.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20050201
Title: The protein kinase C inhibitor Go6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] potentiates agonist-induced mitogen-activated protein kinase activation through tyrosine phosphorylation of the epidermal growth factor receptor.
Journal: Molecular pharmacology 20050101
Title: Oxidant-mediated activation of cytosolic phospholipase a(2) in pulmonary endothelium: role of protein kinase C alpha and a pertussis toxin-sensitive protein.
Journal: Endothelium : journal of endothelial cell research 20050101
Title: Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: implications in carcinogenesis.
Journal: The Journal of biological chemistry 20041217
Title: IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes.
Journal: Microbes and infection 20041101
Title: Mechanisms of hydroxyl radical-induced contraction of rat aorta.
Journal: European journal of pharmacology 20040919
Title: Phospholipase D isozymes mediate epigallocatechin gallate-induced cyclooxygenase-2 expression in astrocyte cells.
Journal: The Journal of biological chemistry 20040910
Title: TIS21/BTG2/PC3 is expressed through PKC-delta pathway and inhibits binding of cyclin B1-Cdc2 and its activity, independent of p53 expression.
Journal: Experimental cell research 20040910
Title: Enhancement of fibronectin fibrillogenesis and bone formation by basic fibroblast growth factor via protein kinase C-dependent pathway in rat osteoblasts.
Journal: Molecular pharmacology 20040901
Title: Protein kinase C alpha/beta inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells.
Journal: Cancer research 20040815
Title: B cell receptor-induced cAMP-response element-binding protein activation in B lymphocytes requires novel protein kinase Cdelta.
Journal: The Journal of biological chemistry 20040716
Title: PfPKB, a novel protein kinase B-like enzyme from Plasmodium falciparum: I. Identification, characterization, and possible role in parasite development.
Journal: The Journal of biological chemistry 20040604
Title: Salmonella typhimurium SipA-induced neutrophil transepithelial migration: involvement of a PKC-alpha-dependent signal transduction pathway.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040601
Title: PKA-dependent activation of PKC, p38 MAPK and IKK in macrophage: implication in the induction of inducible nitric oxide synthase and interleukin-6 by dibutyryl cAMP.
Journal: Cellular signalling 20040501
Title: Effects of maribavir and selected indolocarbazoles on Epstein-Barr virus protein kinase BGLF4 and on viral lytic replication.
Journal: Antimicrobial agents and chemotherapy 20040501
Title: Transcription factor Ets-1 mediates ischemia- and vascular endothelial growth factor-dependent retinal neovascularization.
Journal: The American journal of pathology 20040501
Title: Involvement of protein kinase C-related anti-apoptosis signaling in radiation-induced apoptosis in murine thymic lymphoma(3SBH5) cells.
Journal: Radiation research 20040501
Title: Phospholipase D is involved in oxidative stress-induced migration of vascular smooth muscle cells via tyrosine phosphorylation and protein kinase C.
Journal: Experimental & molecular medicine 20040430
Title: Expressions of inhibitory Smads, Smad6 and Smad7, are differentially regulated by TPA in human lung fibroblast cells.
Journal: Biochemical and biophysical research communications 20040409
Title: Identification of proteins differentially expressed during chondrogenesis of mesenchymal cells.
Journal: FEBS letters 20040409
Title: Cooperation between PKC-alpha and PKC-epsilon in the regulation of JNK activation in human lung cancer cells.
Journal: Cellular signalling 20040401
Title: Development of a microplate bioassay for monocyte chemoattractant protein-1 based on activation of p44/42 mitogen-activated protein kinase.
Journal: Analytical biochemistry 20040401
Title: Signaling pathways for arsenic-stimulated vascular endothelial growth factor-a expression in primary vascular smooth muscle cells.
Journal: Chemical research in toxicology 20040401
Title: Muscarinic M2 receptor stimulation of Cav1.2b requires phosphatidylinositol 3-kinase, protein kinase C, and c-Src.
Journal: Circulation research 20040319
Title: Ca2+-dependent protein kinase C isoforms induce cholestasis in rat liver.
Journal: The Journal of biological chemistry 20040312
Title: Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells.
Journal: European journal of pharmacology 20040220
Title: Differential modulation of CaV2.3 Ca2+ channels by Galphaq/11-coupled muscarinic receptors.
Journal: Molecular pharmacology 20040201
Title: Celecoxib simulates respiratory burst through pertussis toxin-sensitive G-protein, a possible signal for beta 2-integrin expression on human neutrophils.
Journal: European journal of pharmacology 20040119
Title: Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423.
Journal: Biochemical pharmacology 20040115
Title: Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein.
Journal: The Journal of biological chemistry 20040102
Title: Activation of P2X7 purinoceptor-stimulated TGF-beta 1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line, RBA-2.
Journal: Cellular signalling 20031201
Title: Possible role of the protein kinase C/CPI-17 pathway in the augmented contraction of human myometrium after gestation.
Journal: British journal of pharmacology 20031201
Title: Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression.
Journal: International immunology 20031201
Title: Protein kinase C (PKC) isotype profile in eosinophils from ponies with sweet itch and role in histamine-induced eosinophil activation.
Journal: Veterinary immunology and immunopathology 20031115
Title: Protein kinase C-dependent potentiation of intracellular calcium influx by sigma1 receptor agonists in rat hippocampal neurons.
Journal: The Journal of pharmacology and experimental therapeutics 20031101
Title: Pharmacological analysis of signal transduction pathways required for oxidative burst in chicken heterophils stimulated by a Toll-like receptor 2 agonist.
Journal: International immunopharmacology 20031101
Title: Inhibition of protein kinase Calpha enhances anticancer agent-induced loss of anchorage-independent growth regardless of protection against apoptosis by Bcl-2.
Journal: Molecular pharmacology 20031001
Title: Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity.
Journal: European journal of biochemistry 20031001
Title: Involvement of stress-activated protein kinase/c-Jun N-terminal kinase in endothelin-1-induced heat shock protein 27 in osteoblasts.
Journal: European journal of endocrinology 20030901
Title: Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
Journal: British journal of pharmacology 20030901
Title: Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.
Journal: Cancer research 20030815
Title: Protein kinase C modifications of VE-cadherin, p120, and beta-catenin contribute to endothelial barrier dysregulation induced by thrombin.
Journal: American journal of physiology. Lung cellular and molecular physiology 20030801
Title: Nuclear factor of activated T cells 2 transactivation in mast cells: a novel isoform-specific transactivation domain confers unique FcepsilonRI responsiveness.
Journal: The Journal of biological chemistry 20030718
Title: Ca(2+)-independent protein kinase C activity is required for alpha1-adrenergic-receptor-mediated regulation of ribosomal protein S6 kinases in adult cardiomyocytes.
Journal: The Biochemical journal 20030715
Title: Activation of protein kinase C delta by IFN-gamma.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030701
Title: Unique T cell proliferation associated with PKCmu activation and impaired ZAP-70 phosphorylation in recognition of overexpressed HLA/partially agonistic peptide complexes.
Journal: European journal of immunology 20030601
Title: Role of protein kinase C isoforms in rat epididymal microvascular endothelial barrier function.
Journal: American journal of respiratory cell and molecular biology 20030501
Title: Conventional-type protein kinase C contributes to phorbol ester-induced inhibition of rat myometrial tension.
Journal: British journal of pharmacology 20030501
Title: Nongenomic mechanism of glucocorticoid inhibition of bradykinin-induced calcium influx in PC12 cells: possible involvement of protein kinase C.
Journal: Life sciences 20030418
Title: Cyclical mechanical stretch enhances angiopoietin-2 and Tie2 receptor expression in cultured human umbilical vein endothelial cells.
Journal: Clinical science (London, England : 1979) 20030401
Title: Hyperoxia alters phorbol ester-induced phospholipase D activation in bovine lung microvascular endothelial cells.
Journal: Antioxidants & redox signaling 20030401
Title: Depolymerization of actin filament by cytochalasin E induces interleukin-8 production and up-regulates CD54 in the HeLa epithelial cell line.
Journal: Microbiology and immunology 20030101
Title: Hyperglycemia-induced protein kinase C activation inhibits phagocytosis of C3b- and immunoglobulin g-opsonized yeast particles in normal human neutrophils.
Journal: Experimental diabesity research 20030101
Title: Role of specific protein kinase C isozymes in mediating epidermal growth factor, thyrotropin-releasing hormone, and phorbol ester regulation of the rat prolactin promoter in GH4/GH4C1 pituitary cells.
Journal: Molecular endocrinology (Baltimore, Md.) 20021201
Title: Involvement of classical and novel protein kinase C isoforms in the response of human V gamma 9V delta 2 T cells to phosphate antigens.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20021115
Title: Opposing effects of PKCalpha and PKCepsilon on basolateral membrane dynamics in intestinal epithelia.
Journal: American journal of physiology. Cell physiology 20021101
Title: Modulation of steroid hydroxylase activity in stably transfected V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors.
Journal: Endocrine research 20021101
Title: Conventional protein kinase C mediates phorbol-dibutyrate-induced cytoskeletal remodeling in a7r5 smooth muscle cells.
Journal: Experimental cell research 20021015
Title: Regulation of the neuronal glutamate transporter excitatory amino acid carrier-1 (EAAC1) by different protein kinase C subtypes.
Journal: Molecular pharmacology 20021001
Title: Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells.
Journal: Experimental hematology 20020901
Title: Lipoteichoic acid-induced cyclooxygenase-2 expression requires activations of p44/42 and p38 mitogen-activated protein kinase signal pathways.
Journal: European journal of pharmacology 20020816
Title: Activation of angiotensin II type I receptor promotes protein kinase C translocation and cell proliferation in human cultured breast epithelial cells.
Journal: The Journal of endocrinology 20020801
Title: Putative conventional protein kinase C inhibitor Gödecke 6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] stimulates transglutaminase activity in primary mouse epidermal keratinocytes.
Journal: The Journal of pharmacology and experimental therapeutics 20020701
Title: Different actions of protein kinase C isoforms alpha and epsilon on gastric acid secretion.
Journal: British journal of pharmacology 20020701
Title: Mechanism of angiotensin II-induced phospholipase D activation in bovine adrenal glomerulosa cells.
Journal: Molecular and cellular endocrinology 20020628
Title: FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway.
Journal: Biochemical and biophysical research communications 20020517
Title: Calcium-dependent involucrin expression is inversely regulated by protein kinase C (PKC)alpha and PKCdelta.
Journal: The Journal of biological chemistry 20020510
Title: Blocking NF-kappaB activation in Jurkat leukemic T cells converts the survival agent and tumor promoter PMA into an apoptotic effector.
Journal: Oncogene 20020509
Title: Direct targeting of human cytomegalovirus protein kinase pUL97 by kinase inhibitors is a novel principle for antiviral therapy.
Journal: The Journal of general virology 20020501
Title: Fas activation opposes PMA-stimulated changes in the localization of PKCdelta: a mechanism for reducing neutrophil adhesion to endothelial cells.
Journal: Journal of leukocyte biology 20020501
Title: Antagonists of protein kinase C inhibit rat retinal glutamate transport activity in situ.
Journal: Journal of neurochemistry 20020501
Title: Involvement of protein kinase D in Fc gamma-receptor activation of the NADPH oxidase in neutrophils.
Journal: The Biochemical journal 20020401
Title: Transforming growth factor-beta stabilizes elastin mRNA by a pathway requiring active Smads, protein kinase C-delta, and p38.
Journal: American journal of respiratory cell and molecular biology 20020201
Title: A critical protein kinase C phosphorylation site on the 5-HT(1A) receptor controlling coupling to N-type calcium channels.
Journal: The Journal of physiology 20020101
Title: Participation of high glucose concentrations in neutrophil adhesion and surface expression of adhesion molecules on cultured human endothelial cells: effect of antidiabetic medicines.
Journal: Journal of diabetes and its complications 20020101
Title: 12(S)-HETE, pleiotropic functions, multiple signaling pathways.
Journal: Advances in experimental medicine and biology 20020101
Title: Peroxisome proliferator-activated receptor gamma ligands inhibit mitogenic induction of p21(Cip1) by modulating the protein kinase Cdelta pathway in vascular smooth muscle cells.
Journal: The Journal of biological chemistry 20011214
Title: Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis.
Journal: The Journal of biological chemistry 20011130
Title: Regulation of matrix metalloproteinase-2 production by cytokines and pharmacological agents in human pulp cell cultures.
Journal: Journal of endodontics 20011101
Title: Rapid activation of ERK1/2 mitogen-activated protein kinase by corticosterone in PC12 cells.
Journal: Biochemical and biophysical research communications 20011005
Title: Pharmacological comparison of LTB(4)-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils.
Journal: British journal of pharmacology 20011001
Title: Noradrenaline and alpha-adrenergic signaling induce the hsp70 gene promoter in mollusc immune cells.
Journal: Journal of cell science 20011001
Title: Protein kinase C modulates telomerase activity in human cervical cancer cells.
Journal: Experimental & molecular medicine 20010930
Title: Fibroblast growth factor activation of the rat PRL promoter is mediated by PKCdelta.
Journal: Molecular endocrinology (Baltimore, Md.) 20010901
Title: Involvement of protein kinase C-delta in DNA damage-induced apoptosis.
Journal: Cell death and differentiation 20010901
Title: Pharmacological evidence for system-dependent involvement of protein kinase C isoenzymes in phorbol ester-suppressed gap junctional communication.
Journal: Experimental cell research 20010815
Title: Neurotrophin secretion from cultured microglia.
Journal: Journal of neuroscience research 20010815
Title: Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms.
Journal: The Journal of biological chemistry 20010803
Title: Dual regulation of sphingosine 1-phosphate-induced phospholipase D activity through RhoA and protein kinase C-alpha in C2C12 myoblasts.
Journal: Cellular signalling 20010801
Title: Protein kinase C epsilon suppresses Abeta production and promotes activation of alpha-secretase.
Journal: Biochemical and biophysical research communications 20010727
Title: Serotonin activation of the ERK pathway in Hermissenda: contribution of calcium-dependent protein kinase C.
Journal: Journal of neurochemistry 20010701
Title: Expression of protein kinase C isoforms in euxanthone-induced differentiation of neuroblastoma cells.
Journal: Planta medica 20010701
Title: Inhibitors of human cytomegalovirus replication drastically reduce the activity of the viral protein kinase pUL97.
Journal: The Journal of general virology 20010601
Title: Oxytocin stimulates prostaglandin F2alpha secretion from porcine endometrial cells through activation of calcium-dependent protein kinase C.
Journal: Prostaglandins & other lipid mediators 20010601
Title: Effects of protein kinase C inhibitors on insulin secretory responses from rodent pancreatic islets.
Journal: Molecular and cellular endocrinology 20010525
Title: Adenosine nucleotides acting at the human P2Y1 receptor stimulate mitogen-activated protein kinases and induce apoptosis.
Journal: The Journal of biological chemistry 20010511
Title: Effect of protein kinase C inhibition on hypoxic pulmonary vasoconstriction.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010501
Title: Importance of PKC and PI3Ks in ethanol-induced contraction of cerebral arterial smooth muscle.
Journal: American journal of physiology. Heart and circulatory physiology 20010501
Title: Heterogeneous increases of cytoplasmic calcium: distinct effects on down-regulation of cell surface sodium channels and sodium channel subunit mRNA levels.
Journal: British journal of pharmacology 20010401
Title: The role of protein kinase C in the regulation of serotonin-2A receptor expression.
Journal: Journal of neurochemistry 20010401
Title: Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.
Journal: Journal of leukocyte biology 20010401
Title: Signal transduction of flumazenil-induced preconditioning in myocytes.
Journal: American journal of physiology. Heart and circulatory physiology 20010301
Title: Use of protein kinase C inhibitors results in rapid [Mg(2+)](i) mobilization in primary cultured rat aortic smooth muscle cells: are certain kinase C isoforms natural homeostatic regulators of cystolic free Mg(2+).
Journal: European journal of pharmacology 20010216
Title: Il-4 and IL-13, but not IL-10, protect human synoviocytes from apoptosis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010215
Title: Oxidized-LDL enhances coronary vasoconstriction by increasing the activity of protein kinase C isoforms alpha and epsilon.
Journal: Hypertension (Dallas, Tex. : 1979) 20010201
Title: The overexpression of PKCdelta is involved in vascular endothelial growth factor-resistant apoptosis in cultured primary sinusoidal endothelial cells.
Journal: Biochemical and biophysical research communications 20010112
Title: A potential role for protein kinase C-epsilon in regulating megakaryocytic lineage commitment.
Journal: The Journal of biological chemistry 20010105
Title: Differential regulation of microglial NO production by protein kinase C inhibitors.
Journal: Neurochemistry international 20010101
Title: Effects of PKC isozyme inhibitors on constrictor responses in the feline pulmonary vascular bed.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010101
Title: Role for phospholipase D in receptor-mediated endocytosis.
Journal: Molecular and cellular biology 20010101
Title: Modulation of noradrenaline-induced microvascular constriction by protein kinase inhibitors.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010101
Title: Bradykinin induces protein kinase C-dependent activation of phospholipase D in A-431 cells.
Journal: IUBMB life 20010101
Title: Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Journal: The Biochemical journal 20001001
Title: Indolocarbazoles exhibit strong antiviral activity against human cytomegalovirus and are potent inhibitors of the pUL97 protein kinase.
Journal: Antiviral research 20001001
Title: Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability.
Journal: Circulation research 20000107
Title: Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes.
Journal: FEBS letters 19960826
Title: Novel indolocarbazole protein kinase C inhibitors prevent reactivation of HIV-1 in latently infected cells.
Journal: Antiviral research 19931201
Title: Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.
Journal: The Journal of biological chemistry 19930505
Title: Qatsha KA, et al. Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro. Proc Natl Acad Sci U S A. 1993 May 15;90(10):4674-8.
Title: Hayamitsu Adachi, et al. Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology. The Journal of Antibiotics volume 71, pages 60–71 (2018).
Title: Mahmoudian S, et al. Influenza A virus proteins PB1 and NS1 are subject to functionally important phosphorylation by protein kinase C. J Gen Virol. 2009;90(Pt 6):1392-1397.
