[1]Fukami;Nagase;Fujita;Hayama;Niiyama;Mase;Nakajima;Fukuroda;Saeki;Nishikibe;Ihara;Yano;Ishikawa[JournalofMedicinalChemistry,1995,vol.38,#21,p.4309-4324]
[2]Ishikawa,Kiyofumi;Fukami,Takehiro;Nagase,Toshio;Fujita,Kagari;Hayama,Takashi;etal.[JournalofMedicinalChemistry,1992,vol.35,#11,p.2139-2142]
[1]Fukami;Nagase;Fujita;Hayama;Niiyama;Mase;Nakajima;Fukuroda;Saeki;Nishikibe;Ihara;Yano;Ishikawa[JournalofMedicinalChemistry,1995,vol.38,#21,p.4309-4324]
[1]Fukami;Nagase;Fujita;Hayama;Niiyama;Mase;Nakajima;Fukuroda;Saeki;Nishikibe;Ihara;Yano;Ishikawa[JournalofMedicinalChemistry,1995,vol.38,#21,p.4309-4324]
[1]Fukami;Nagase;Fujita;Hayama;Niiyama;Mase;Nakajima;Fukuroda;Saeki;Nishikibe;Ihara;Yano;Ishikawa[JournalofMedicinalChemistry,1995,vol.38,#21,p.4309-4324]
[1]Spatola,ArnoF.;Crozet,Yvon;DeWit,Damiane;Yanagisawa,Masashi[JournalofMedicinalChemistry,1996,vol.39,#19,p.3842-3846]
Title: Induction of endothelium-dependent constriction of mesenteric arteries in endotoxemic hypotensive shock.
Journal: British journal of pharmacology 20160401
Title: BQ-123 prevents LPS-induced preterm birth in mice via the induction of uterine and placental IL-10.
Journal: Toxicology and applied pharmacology 20150201
Title: Activation of the endothelin system mediates pathological angiogenesis during ischemic retinopathy.
Journal: The American journal of pathology 20141101
Title: Selective ET(A) receptor blockade protects against cisplatin-induced acute renal failure in male rats.
Journal: European journal of pharmacology 20140505
Title: Vascular endothelial growth factor-C modulates proliferation and chemoresistance in acute myeloid leukemic cells through an endothelin-1-dependent induction of cyclooxygenase-2.
Journal: Biochimica et biophysica acta 20140201
Title: Interplay between endothelin and erythropoietin in astroglia: the role in protection against hypoxia.
Journal: International journal of molecular sciences 20140201
Title: Endothelin-1 increases superoxide production in human coronary artery bypass grafts.
Journal: Life sciences 20121015
Title: The adipokine chemerin augments vascular reactivity to contractile stimuli via activation of the MEK-ERK1/2 pathway.
Journal: Life sciences 20121015
Title: The influence of ETA and ETB receptor blockers on LPS-induced oxidative stress and NF-κB signaling pathway in heart.
Journal: General physiology and biophysics 20120901
Title: Cathepsin E induces itch-related response through the production of endothelin-1 in mice.
Journal: European journal of pharmacology 20120705
Title: Agonist-dependent modulation of arterial endothelinA receptor function.
Journal: British journal of pharmacology 20120701
Title: Endothelin 1-dependent neurovascular dysfunction in chronic intermittent hypoxia.
Journal: Hypertension (Dallas, Tex. : 1979) 20120701
Title: Blocking endothelin-B receptors rescues retinal ganglion cells from optic nerve injury through suppression of neuroinflammation.
Journal: Investigative ophthalmology & visual science 20120608
Title: Ouabain stimulates atrial natriuretic peptide secretion via the endothelin-1/ET(B) receptor-mediated pathway in beating rabbit atria.
Journal: Life sciences 20120522
Title: Elevated endothelin-1 vasoconstrictor tone in prehypertensive adults.
Journal: The Canadian journal of cardiology 20120501
Title: EndothelinA-endothelinB receptor cross-talk in rat basilar artery in situ.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120401
Title: Modulation by endothelin-1 of spontaneous activity and membrane currents of atrioventricular node myocytes from the rabbit heart.
Journal: PloS one 20120101
Title: Fluorescence correlation spectroscopy in drug discovery: study of Alexa532-endothelin 1 binding to the endothelin ETA receptor to describe the pharmacological profile of natural products.
Journal: TheScientificWorldJournal 20120101
Title: Endothelin-1 stimulates small artery VCAM-1 expression through p38MAPK-dependent neutral sphingomyelinase.
Journal: Journal of vascular research 20120101
Title: Pharmacological differences of endothelin receptors-mediated modulation in cultured interstitial cells of Cajal from the murine small and large intestine.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Endothelin-1 in paraventricular nucleus modulates cardiac sympathetic afferent reflex and sympathetic activity in rats.
Journal: PloS one 20120101
Title: Age-associated alterations in retinal arteriole reactivity to endothelin-1 differ between the sexes.
Journal: Mechanisms of ageing and development 20120101
Title: ETA and ETB receptors are expressed in vascular adventitial fibroblasts.
Journal: American journal of physiology. Heart and circulatory physiology 20111201
Title: Endothelin-1 promotes osteosarcoma cell invasion and survival against cisplatin-induced apoptosis.
Journal: Clinical orthopaedics and related research 20111101
Title: Endothelin-induced changes in blood flow in STZ-diabetic and non-diabetic rats: relation to nitric oxide synthase and cyclooxygenase inhibition.
Journal: The journal of physiological sciences : JPS 20111101
Title: Low-intensity interval exercise training attenuates coronary vascular dysfunction and preserves Ca²⁺-sensitive K⁺ current in miniature swine with LV hypertrophy.
Journal: American journal of physiology. Heart and circulatory physiology 20111001
Title: Irregular electrical activation of intrinsic cardiac adrenergic cells increases catecholamine-synthesizing enzymes.
Journal: Biochemical and biophysical research communications 20110930
Title: Exogenous ghrelin improves blood flow distribution in pulmonary hypertension-assessed using synchrotron radiation microangiography.
Journal: Pflugers Archiv : European journal of physiology 20110901
Title: Endothelin-1 vasoconstriction and the age-related decline in endothelium-dependent vasodilatation in men.
Journal: Clinical science (London, England : 1979) 20110601
Title: Tobacco-associated pulmonary vascular dysfunction in smokers: role of the ET-1 pathway.
Journal: American journal of physiology. Lung cellular and molecular physiology 20110601
Title: Cyclosporine A-induced acute hepatotoxicity in guinea pigs is associated with endothelin-mediated decrease in local hepatic blood flow.
Journal: Life sciences 20110425
Title: 20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II and endothelin-1.
Journal: American journal of physiology. Heart and circulatory physiology 20110401
Title: Effect of avosentan (SPP-301) in porcine ciliary arteries.
Journal: Current eye research 20110201
Title: From a molecular biological viewpoint, does endothelin type A receptor antagonist therapy reduce diabetes-induced testicular damage in rats?
Journal: Urology 20110101
Title: Endothelin-A receptor antagonists prevent amyloid-β-induced increase in ETA receptor expression, oxidative stress, and cognitive impairment.
Journal: Journal of Alzheimer's disease : JAD 20110101
Title: Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis.
Journal: Arthritis research & therapy 20110101
Title: Protective effects of endothelin-A receptor antagonist BQ123 against LPS-induced oxidative stress in lungs.
Journal: Pharmacological reports : PR 20110101
Title: Glial response to lipopolysaccharide: possible role of endothelins.
Journal: Peptides 20101201
Title: Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cδ.
Journal: Clinical and experimental pharmacology & physiology 20101201
Title: Endothelin receptor antagonist BQ-123 ameliorates myocardial ischemic-reperfusion injury in rats: a hemodynamic, biochemical, histopathological and electron microscopic evidence.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20101101
Title: Molecular signaling of pruritus induced by endothelin-1 in mice.
Journal: Experimental biology and medicine (Maywood, N.J.) 20101101
Title: Endothelin-A receptor antagonist BQ123 potentiates acetaminophen induced hypothermia and reduces infarction following focal cerebral ischemia in rats.
Journal: European journal of pharmacology 20101010
Title: Effects of cardiopulmonary bypass on endothelin-1-induced contraction and signaling in human skeletal muscle microcirculation.
Journal: Circulation 20100914
Title: Inhibition of endothelin-1 receptors improves impaired nitric oxide synthase-dependent dilation of cerebral arterioles in type-1 diabetic rats.
Journal: Microcirculation (New York, N.Y. : 1994) 20100801
Title: Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries.
Journal: Circulation research 20100723
Title: Endothelin-A receptor antagonism attenuates carcinoma-induced pain through opioids in mice.
Journal: The journal of pain : official journal of the American Pain Society 20100701
Title: Endothelin-1-induced contractile responses of human coronary arterioles via endothelin-A receptors and PKC-alpha signaling pathways.
Journal: Surgery 20100601
Title: Simvastatin stimulates production of the antiapoptotic protein Bcl-2 via endothelin-1 and NFATc3 in SH-SY5Y cells.
Journal: Molecular neurobiology 20100601
Title: Activation of endothelin A receptors contributes to impaired responsiveness of renal mechanosensory nerves in congestive heart failure.
Journal: Canadian journal of physiology and pharmacology 20100601
Title: Acute effects of endothelin receptor antagonists on hepatic hemodynamics of cirrhotic and noncirrhotic rats.
Journal: Canadian journal of physiology and pharmacology 20100601
Title: Endothelium-derived endothelin-1.
Journal: Pflugers Archiv : European journal of physiology 20100501
Title: Regulation of glucose uptake by endothelin-1 in human skeletal muscle in vivo and in vitro.
Journal: The Journal of clinical endocrinology and metabolism 20100501
Title: [The mechanism and pulmonary-protective effects of endothelin-1 receptor antagonist in chronic obstructive pulmonary diseases rat model].
Journal: Zhonghua nei ke za zhi 20100501
Title: The vasodilatory effect of juxta-arteriolar microinjection of endothelinA receptor inhibitor in healthy and acute branch retinal vein occlusion minipig retinas.
Journal: Investigative ophthalmology & visual science 20100401
Title: Endothelin-1 receptor antagonists prevent the development of pulmonary emphysema in rats.
Journal: The European respiratory journal 20100401
Title: Attenuation of Doxorubicin-induced cardiomyopathy by endothelin-converting enzyme-1 ablation through prevention of mitochondrial biogenesis impairment.
Journal: Hypertension (Dallas, Tex. : 1979) 20100301
Title: Sex differences in endothelin-1-mediated vasoconstrictor tone in middle-aged and older adults.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100201
Title: Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction.
Journal: Peptides 20100201
Title: Role of endogenous ET-1 in the regulation of myocardial blood flow in lean and obese humans.
Journal: Obesity (Silver Spring, Md.) 20100101
Title: Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure.
Journal: Heart failure reviews 20100101
Title: Production and binding of endothelin-2 (EDN2) in the rat ovary: endothelin receptor subtype A (EDNRA)-mediated contraction.
Journal: Reproduction, fertility, and development 20100101
Title: Ablation of transient receptor potential vanilloid 1 abolishes endothelin-induced increases in afferent renal nerve activity: mechanisms and functional significance.
Journal: Hypertension (Dallas, Tex. : 1979) 20091201
Title: Endothelin-1 induces the expression of C-reactive protein in rat vascular smooth muscle cells.
Journal: Biochemical and biophysical research communications 20091120
Title: [Cardioprotection of ramipril and BQ-123 against myocardial ischemia/reperfusion injury in vivo in rats].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20091101
Title: Dietary sodium modulates the interaction between efferent renal sympathetic nerve activity and afferent renal nerve activity: role of endothelin.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090801
Title: Role of ET(A) and ET(B) endothelin receptors on endothelin-1-induced potentiation of nociceptive and thermal hyperalgesic responses evoked by capsaicin in rats.
Journal: Neuroscience letters 20090703
Title: Functional and molecular characterization of the endothelin system in retinal arterioles.
Journal: Investigative ophthalmology & visual science 20090701
Title: Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-a receptor antagonism in chronic kidney disease.
Journal: Hypertension (Dallas, Tex. : 1979) 20090701
Title: Angiotensin II-induced increase in myocardial distensibility and its modulation by the endocardial endothelium in the rabbit heart.
Journal: Experimental physiology 20090601
Title: Improved endothelial function after endothelin receptor blockade in patients with systemic sclerosis.
Journal: Arthritis and rheumatism 20090601
Title: Involvement of NO and MEK/ERK pathway in enhancement of endothelin-1-induced mesenteric artery contraction in later-stage type 2 diabetic Goto-Kakizaki rat.
Journal: American journal of physiology. Heart and circulatory physiology 20090501
Title: Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1-mediated pathways.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090401
Title: The effect of endothelin-1 on alveolar fluid clearance and pulmonary edema formation in the rat.
Journal: Anesthesia and analgesia 20090101
Title: Normothermic perfusion of ischaemic porcine kidneys: an evaluation of ex vivo function and endothelin receptor antagonism.
Journal: Journal of nephrology 20090101
Title: Selective endothelin A-receptor blockade attenuates coronary microvascular dysfunction after coronary stenting in patients with type 2 diabetes.
Journal: Vascular health and risk management 20090101
Title: Endothelin A receptor antagonist modulates lymphocyte and eosinophil infiltration, hyperreactivity and mucus in murine asthma.
Journal: International immunopharmacology 20081220
Title: Molecular analysis of cocaine-induced endothelial dysfunction: role of endothelin-1 and nitric oxide.
Journal: Cardiovascular toxicology 20081201
Title: Regulation of glial inflammatory mediators synthesis: possible role of endothelins.
Journal: Peptides 20081201
Title: Adenosine 5'-tetraphosphate is a highly potent purinergic endothelium-derived vasoconstrictor.
Journal: Circulation research 20081107
Title: Endothelium-derived vasoconstriction by purines and pyrimidines.
Journal: Circulation research 20081107
Title: Role of nitric oxide in regulation of retinal blood flow in response to hyperoxia in cats.
Journal: Investigative ophthalmology & visual science 20081001
Title: Pharmacological characterization of 3-azabicyclo[3,2,1] octane-1-yl-l-leucyl-d-tryptophanyl-d-4-Cl-phenylalanine: A novel ET(A) receptor-selective antagonist.
Journal: Pulmonary pharmacology & therapeutics 20081001
Title: The endothelin-converting enzyme-1/endothelin-1 pathway plays a critical role in inflammation-associated premature delivery in a mouse model.
Journal: The American journal of pathology 20081001
Title: Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-alpha, and CXCL-1.
Journal: Journal of leukocyte biology 20080901
Title: Endothelin-1 regulates cardiac L-type calcium channels via NAD(P)H oxidase-derived superoxide.
Journal: The Journal of pharmacology and experimental therapeutics 20080901
Title: Aldosterone induces interleukin-18 through endothelin-1, angiotensin II, Rho/Rho-kinase, and PPARs in cardiomyocytes.
Journal: American journal of physiology. Heart and circulatory physiology 20080901
Title: The role of endothelin pathway in modulation of airway reactivity to methacholine in C57Bl/6 and BALB/c mice.
Journal: European journal of pharmacology 20080820
Title: ADP-ribosyl cyclase and ryanodine receptors mediate endothelin ETA and ETB receptor-induced renal vasoconstriction in vivo.
Journal: American journal of physiology. Renal physiology 20080801
Title: Antagonism of endothelin-1 inhibits hypoxia-induced apoptosis in cardiomyocytes.
Journal: Canadian journal of physiology and pharmacology 20080801
Title: Chronic ethanol intake modulates vascular levels of endothelin-1 receptor and enhances the pressor response to endothelin-1 in anaesthetized rats.
Journal: British journal of pharmacology 20080701
Title: Effect of chronic and selective endothelin receptor antagonism on microvascular function in type 2 diabetes.
Journal: American journal of physiology. Heart and circulatory physiology 20080601
Title: Endothelin receptor blockers protect against ischemia/reperfusion impairment of gastrointestinal motility in rats.
Journal: Pharmacological research 20080601
Title: Role of endothelin receptors on basal and endothelin-1-stimulated lung myofibroblast proliferation.
Journal: Canadian journal of physiology and pharmacology 20080601
Title: Central endothelin: effects on vasopressin and the arterial baroreflex in doxorubicin heart failure rats.
Journal: Canadian journal of physiology and pharmacology 20080601
Title: Potentiation of 2-methoxyestradiol-induced cytotoxicity by blocking endothelin A receptor in prostate cancer cells.
Journal: The Prostate 20080501
Title: Contractile changes of the clitoral cavernous smooth muscle in female rabbits with experimentally induced overactive bladder.
Journal: The journal of sexual medicine 20080501
Title: Effects of endothelin receptor type-A and type-B antagonists on prostaglandin F2alpha-induced luteolysis of the sheep corpus luteum.
Journal: Biology of reproduction 20080401
Title: Interruption of endothelin signaling modifies membrane type 1 matrix metalloproteinase activity during ischemia and reperfusion.
Journal: American journal of physiology. Heart and circulatory physiology 20080201
Title: Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K+ channel expression in pulmonary arterial myocytes.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080201
Title: Intracellular mechanisms and receptor types for endothelin-1-induced positive and negative inotropy in mouse ventricular myocardium.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080201
Title: Expression of the hyperpolarization-activated current, I(f), in cultured adult rat ventricular cardiomyocytes and its modulation by hypertrophic factors.
Journal: Pharmacological research 20080201
Title: Effects of endothelin-1 1-31 on cell viabililty and [Ca2+]i in cultured neonatal rat cardiomyocytes.
Journal: Physiological research 20080101
Title: The endothelin-1 pathway and the development of cardiovascular defects in the haemodynamically challenged chicken embryo.
Journal: Journal of vascular research 20080101
Title: 19F NMR in vivo spectroscopy reflects the effectiveness of perfusion-enhancing vascular modifiers for improving gemcitabine chemotherapy.
Journal: Magnetic resonance in medicine 20080101
Title: Endothelin-1 potentiation of coronary artery contraction after ischemia-reperfusion.
Journal: Vascular pharmacology 20080101
Title: Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation.
Journal: Journal of cardiovascular pharmacology 20071201
Title: Altered role of smooth muscle endothelin receptors in coronary endothelin-1 and alpha1-adrenoceptor-mediated vasoconstriction in Type 2 diabetes.
Journal: American journal of physiology. Heart and circulatory physiology 20071001
Title: NADPH oxidase mediates angiotensin II-induced endothelin-1 expression in vascular adventitial fibroblasts.
Journal: Cardiovascular research 20070901
Title: Involvement of inducible nitric oxide synthase in blood flow decrease in vein induced by hen-egg white lysozyme.
Journal: Biological & pharmaceutical bulletin 20070701
Title: Endothelin-1 and pancreatic islet vasculature: studies in vivo and on isolated, vascularly perfused pancreatic islets.
Journal: American journal of physiology. Endocrinology and metabolism 20070601
Title: Peripheral endothelin A receptor antagonism attenuates carcinoma-induced pain.
Journal: European journal of pain (London, England) 20070501
Title: Endothelin-1 activates ETA receptors to cause reflex scratching in BALB/c mice.
Journal: British journal of pharmacology 20070501
Title: Endogenous endothelin in human coronary vascular function: differential contribution of endothelin receptor types A and B.
Journal: Hypertension (Dallas, Tex. : 1979) 20070501
Title: Sarcoplasmic-endoplasmic reticulum Ca2+-ATPase inhibition prevents endothelin A receptor antagonism in rat aorta.
Journal: American journal of physiology. Heart and circulatory physiology 20070401
Title: Endothelins mediate neutrophil activation, ProMMP-9 release and endothelial cell detachment.
Journal: Inflammation 20070401
Title: Mechanisms of direct peritoneal resuscitation-mediated splanchnic hyperperfusion following hemorrhagic shock.
Journal: Shock (Augusta, Ga.) 20070401
Title: Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats.
Journal: Circulation research 20070330
Title: Endothelin-1 induces functionally active CD40 protein via nuclear factor-kappaB in human vascular smooth muscle cells.
Journal: European journal of medical research 20070326
Title: Dual endothelin receptor blockade acutely improves insulin sensitivity in obese patients with insulin resistance and coronary artery disease.
Journal: Diabetes care 20070301
Title: Endothelin limits insulin action in obese/insulin-resistant humans.
Journal: Diabetes 20070301
Title: Intraindividual comparison of human radial and internal thoracic arteries in vitro and the effect of preoperative calcium blocker therapy.
Journal: Fundamental & clinical pharmacology 20070201
Title: Activation of endothelin-a receptors contributes to angiotensin-induced suppression of renal sensory nerve activation.
Journal: Hypertension (Dallas, Tex. : 1979) 20070101
Title: Endothelin-1-mediated wave-like [Ca2+]i oscillations in intact rabbit inferior vena cava.
Journal: Journal of vascular research 20070101
Title: Protection from renal ischemia reperfusion injury by an endothelin-A receptor antagonist BQ-123 in relation to nitric oxide production.
Journal: Toxicology 20061207
Title: Regulation of dHAND protein expression by all-trans retinoic acid through ET-1/ETAR signaling in H9c2 cells.
Journal: Journal of cellular biochemistry 20061001
Title: Myocardial dysfunction and neurohumoral activation without remodeling in left ventricle of monocrotaline-induced pulmonary hypertensive rats.
Journal: American journal of physiology. Heart and circulatory physiology 20061001
Title: Impaired effect of endothelin-1 on coronary artery stiffness in type 2 diabetes.
Journal: International journal of cardiology 20060920
Title: Activation of p38 MAPK is involved in endothelin-1-stimulated COX-2 expression in cultured Feline esophageal smooth muscle cells.
Journal: Molecules and cells 20060831
Title: Ethanol consumption enhances endothelin-1-induced contraction in the isolated rat carotid.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Cerebrovascular dysfunction is an attractive target for therapy in heat stroke.
Journal: Clinical and experimental pharmacology & physiology 20060801
Title: Orofacial cold hyperalgesia due to infraorbital nerve constriction injury in rats: reversal by endothelin receptor antagonists but not non-steroidal anti-inflammatory drugs.
Journal: Pain 20060701
Title: Autocrine effects of endothelin on in vitro proliferation of vascular smooth muscle cells from spontaneously hypertensive and normotensive rats.
Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20060701
Title: Enzymatic pathways involved in the generation of endothelin-1(1-31) from exogenous big endothelin-1 in the rabbit aorta.
Journal: British journal of pharmacology 20060601
Title: Arrhythmogenic action of endothelin-1(1-31) through conversion to endothelin-1(1-21).
Journal: Experimental biology and medicine (Maywood, N.J.) 20060601
Title: Targeting the endothelin axis in human melanoma: combination of endothelin receptor antagonism and alkylating agents.
Journal: Experimental biology and medicine (Maywood, N.J.) 20060601
Title: Effect of BQ-123 and nitric oxide inhibition on liver in rats after renal ischemia-reperfusion injury.
Journal: General physiology and biophysics 20060601
Title: Endothelin-1, an ulcer inducer, promotes gastric ulcer healing via mobilizing gastric myofibroblasts and stimulates production of stroma-derived factors.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060501
Title: Effects of antagonists for endothelin ET(A) and ET(B) receptors on coronary endothelial and myocardial function after ischemia-reperfusion in anesthetized goats.
Journal: Vascular pharmacology 20060501
Title: Endothelin B receptor antagonist increases preproendothelin-1 transcription in bovine aortic endothelial cells and in vivo.
Journal: Journal of cardiovascular pharmacology 20060501
Title: ETa-receptor blockade, but not ACE inhibition, blunts retinal vessel response during isometric exercise.
Journal: American journal of physiology. Heart and circulatory physiology 20060401
Title: Increased vascular angiotensin II binding capacity and ET-1 release in young cardiomyopathic hamsters.
Journal: Vascular pharmacology 20060401
Title: Contribution of endothelin receptors and cyclooxygenase-derivatives to the altered response of the rabbit renal artery to endothelin-1 in diabetes.
Journal: European journal of pharmacology 20060318
Title: Effect of age on insulin-induced endothelin release and vasoreactivity in hypertriglyceridemic and hypertensive rats.
Journal: Experimental gerontology 20060301
Title: Enhanced endothelium-dependent vasodilatation by dual endothelin receptor blockade in individuals with insulin resistance.
Journal: Journal of cardiovascular pharmacology 20060301
Title: Difference in the characteristics of ETA-receptor-stimulated response between rat small pulmonary and renal arteries.
Journal: Journal of cardiovascular pharmacology 20060301
Title: Selective endothelin a (ETA) receptor antagonist (BQ-123) reduces both myocardial infarct size and oxidant injury.
Journal: Toxicology 20060215
Title: Pulmonary perfusion during lipopolysaccharide (LPS) induced fetal endotoxemia in the preterm fetal sheep.
Journal: European journal of obstetrics, gynecology, and reproductive biology 20060201
Title: Positive inter-regulation between beta-catenin/T cell factor-4 signaling and endothelin-1 signaling potentiates proliferation and survival of prostate cancer cells.
Journal: Molecular pharmacology 20060201
Title: Leptin regulates cardiomyocyte contractile function through endothelin-1 receptor-NADPH oxidase pathway.
Journal: Hypertension (Dallas, Tex. : 1979) 20060201
Title: Involvement of endothelium and endothelin-1 in lead-induced smooth muscle cell dysfunction in rats.
Journal: Kidney international 20060201
Title: Pharmacological properties of endothelin-1 in the rabbit corpus cavernosum.
Journal: In vivo (Athens, Greece) 20060101
Title: Endothelin(B) receptor blocker inhibits high glucose-induced synthesis of fibronectin in human peritoneal mesothelial cells.
Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20060101
Title: Effects of endothelin receptor blockade on hypervasoreactivity in streptozotocin-diabetic rats: vessel-specific involvement of thromboxane A2.
Journal: Canadian journal of physiology and pharmacology 20060101
Title: Morphine tolerance does not develop in mice treated with endothelin-A receptor antagonists.
Journal: Brain research 20051207
Title: Endothelin-1 enhances glutamate-induced retinal cell death, possibly through ETA receptors.
Journal: Investigative ophthalmology & visual science 20051201
Title: Blood pressure responses of endothelin-1 1-31 within the rostral ventrolateral medulla through conversion to endothelin-1 1-21.
Journal: Journal of cardiovascular pharmacology 20051201
Title: Inhibition of angiotensin II- and endothelin-1-stimulated proliferation by selective MEK inhibitor in cultured rabbit gingival fibroblastsdagger.
Journal: Fundamental & clinical pharmacology 20051201
Title: Endothelin-1 receptor antagonist BQ123 prevents pulmonary artery hypertension induced by low ambient temperature in broilers.
Journal: Biological & pharmaceutical bulletin 20051201
Title: Endothelins: pathophysiology and treatment implications in chronic heart failure.
Journal: Current heart failure reports 20051201
Title: Pathways of glomerular toxicity of cyclosporine-A: an 'in vitro' study.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20051201
Title: Enhanced response of pig coronary arteries to endothelin-1 after ischemia-reperfusion. Role of endothelin receptors, nitric oxide and prostanoids.
Journal: European journal of pharmacology 20051107
Title: Effect of chymase on intraocular pressure in rabbits.
Journal: European journal of pharmacology 20051107
Title: Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin (ET) acting on ETB receptors in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20051101
Title: Endothelin-1-mediated increase in reactive oxygen species and NADPH Oxidase activity in hearts of aryl hydrocarbon receptor (AhR) null mice.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20051101
Title: Functional characterization and expression of endothelin receptors in rat carotid artery: involvement of nitric oxide, a vasodilator prostanoid and the opening of K+ channels in ETB-induced relaxation.
Journal: British journal of pharmacology 20051101
Title: Glibenclamide reveals role for endothelin in hypoxia-induced vasoconstriction in rat intrapulmonary arteries.
Journal: Journal of cardiovascular pharmacology 20051001
Title: [Effects of airway epithelium injury on the transdifferentiation of sub-epithelial fibroblasts and its role in the development of airway hyperresponsiveness in asthma].
Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20051001
Title: Modulation of the myocardial effects of selective ETB receptor stimulation and its implications for heart failure.
Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20050901
Title: Systemic endothelial dysfunction in adults with cyanotic congenital heart disease.
Journal: Circulation 20050823
Title: Endothelin-1-induced translocation of RhoA is mediated by endothelin ET(A) receptors in rat bronchial smooth muscle.
Journal: European journal of pharmacology 20050711
Title: Nitric oxide inhibition unmasks ischemic myocardium-derived vasoconstrictor signals activating endothelin type A receptor of coronary microvessels.
Journal: American journal of physiology. Heart and circulatory physiology 20050701
Title: Endothelin isoforms and the response to myocardial stretch.
Journal: American journal of physiology. Heart and circulatory physiology 20050601
Title: The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050504
Title: Gender differences in small intestinal perfusion following trauma hemorrhage: the role of endothelin-1.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050501
Title: Exaggerated coronary vasoreactivity to endothelin-1 in aged rats: role of protein kinase C.
Journal: Cardiovascular research 20050501
Title: Cyclo-oxygenase-2, endothelium and aortic reactivity during deoxycorticosterone acetate salt-induced hypertension.
Journal: Journal of hypertension 20050501
Title: Endothelin receptors in lower esophageal sphincter circular smooth muscle.
Journal: Regulatory peptides 20050415
Title: [H]BQ-123 binding to native endothelin ET(A) receptors in human astrocytoma 1321N1 cells and screening of potential ligands.
Journal: Pharmacology 20050401
Title: Endothelin 1 versus endothelin 3 in the development of the slow force response to myocardial stretch.
Journal: The Canadian journal of cardiology 20050401
Title: Cardiovascular effects and lethality of venom from nematocysts of the box-jellyfish Chiropsalmus quadrigatus (Habu-kurage) in anaesthetized rats.
Journal: Toxicon : official journal of the International Society on Toxinology 20050315
Title: Endothelin mediates superoxide production in angiotensin II-induced hypertension in rats.
Journal: Free radical biology & medicine 20050301
Title: Endothelin receptor blockade improves endothelial function in atherosclerotic patients on angiotensin converting enzyme inhibition.
Journal: Journal of internal medicine 20050301
Title: Delphinidin-3-rutinoside relaxes the bovine ciliary smooth muscle through activation of ETB receptor and NO/cGMP pathway.
Journal: Experimental eye research 20050301
Title: Insulin and endothelin in the acute regulation of adiponectin in vivo in humans.
Journal: Obesity research 20050301
Title: Chronic endothelin exposure inhibits connexin43 expression in cultured cortical astroglia.
Journal: Journal of neuroscience research 20050201
Title: Intercellular communication via gap junctions in activated rat hepatic stellate cells.
Journal: Gastroenterology 20050201
Title: [Changes of activity of the endothelial system in experimental heart failure].
Journal: Kardiologiia 20050101
Title: Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.
Journal: Nature 20041125
Title: Mechanisms underlying enhanced contractile response to endothelin-1 in diabetic rat basilar artery.
Journal: Peptides 20041101
Title: A novel combination of opiates and endothelin antagonists to manage pain without any tolerance development.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor.
Journal: Journal of cardiovascular pharmacology 20041101
Title: The impact of respiratory syncytial virus infection on endothelin receptor function and release in sheep bronchial explants.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Synergistic stimulation of aldosterone production in human adrenocortical carcinoma NCI-H295R cells by endothelin-1 and angiotensin II.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Inhibitory actions of endothelin-1 on pain processing.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Pharmacological characterization of YM598, a selective endothelin-A receptor antagonist.
Journal: Journal of cardiovascular pharmacology 20041101
Title: The effect of cerivastatin therapy on vascular responses to endothelin antagonists in humans.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Endothelins induce ETB receptor-mediated mechanical hypernociception in rat hindpaw: roles of cAMP and protein kinase C.
Journal: European journal of pharmacology 20041006
Title: Endothelin-B-receptor-selective antagonist inhibits endothelin-1 induced potentiation on the vasoconstriction to noradrenaline and angiotensin II.
Journal: Journal of hypertension 20041001
Title: Endothelin ETB receptor signaling in the median eminence and subfornical organ of the rat brain.
Journal: Neuropeptides 20041001
Title: Endothelin A receptor antagonism and angiotensin-converting enzyme inhibition are synergistic via an endothelin B receptor-mediated and nitric oxide-dependent mechanism.
Journal: Journal of the American Society of Nephrology : JASN 20041001
Title: Prior antagonism of endothelin-1A receptors alleviates circulatory shock and cerebral ischemia during rat heatstroke.
Journal: Journal of pharmacological sciences 20041001
Title: Association of endothelin with lung hemorrhage induced by immune complexes in rats.
Journal: Inflammation 20041001
Title: Superiority of YM598 over atrasentan as a selective endothelin ETA receptor antagonist.
Journal: European journal of pharmacology 20040913
Title: Prediction of in vivo biliary clearance from the in vitro transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II monolayer expressing both rat organic anion transporting polypeptide 4 and multidrug resistance associated protein 2.
Journal: Molecular pharmacology 20040901
Title: Endothelin upregulates the expression of vasopressin V2 mRNA in the inner medullary collecting duct of the rat.
Journal: Metabolism: clinical and experimental 20040901
Title: Endothelin-1-mediated coronary vasoconstriction deteriorates myocardial depression in hearts isolated from lipopolysaccharide-treated rats: interaction with nitric oxide.
Journal: Clinical and experimental pharmacology & physiology 20040901
Title: [Endothelin-1 and arteriosclerosis].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20040901
Title: [Prospects for endothelin-related drugs].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20040901
Title: Endothelin-1-induced responses in isolated mouse vessels: the expression and function of receptor types.
Journal: American journal of physiology. Heart and circulatory physiology 20040801
Title: Interleukin-18 induces mechanical hypernociception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner.
Journal: The Journal of pharmacology and experimental therapeutics 20040801
Title: Proliferative response to phenytoin and nifedipine in gingival fibroblasts cultured from humans with gingival fibromatosis.
Journal: Fundamental & clinical pharmacology 20040801
Title: Obligatory role for endogenous endothelin in mediating the hypertrophic effects of phenylephrine and angiotensin II in neonatal rat ventricular myocytes: evidence for two distinct mechanisms for endothelin regulation.
Journal: The Journal of pharmacology and experimental therapeutics 20040701
Title: Endothelins and their inhibition in the human skin microcirculation: ET[1-31], a new vasoconstrictor peptide.
Journal: British journal of clinical pharmacology 20040601
Title: Endothelin-induced constriction of the ductus venosus in fetal sheep: developmental aspects and possible interaction with vasodilatory prostaglandin.
Journal: British journal of pharmacology 20040601
Title: [Endothelin].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20040601
Title: Dual effects of endothelin-1 (1-31): induction of mesangial cell migration and facilitation of monocyte recruitment through monocyte chemoattractant protein-1 production by mesangial cells.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20040601
Title: Ventricular nonmyocytes inhibit doxorubicin-induced myocyte apoptosis: involvement of endogenous endothelin-1 as a paracrine factor.
Journal: Endocrinology 20040501
Title: ET-1 induces cortical spreading depression via activation of the ETA receptor/phospholipase C pathway in vivo.
Journal: American journal of physiology. Heart and circulatory physiology 20040401
Title: Regulation of vasopressin secretion by ETA and ETB receptors in compartmentalized rat hypothalamo-neurohypophysial explants.
Journal: American journal of physiology. Endocrinology and metabolism 20040401
Title: Effects of endothelin-1 on portal-systemic collaterals of common bile duct-ligated cirrhotic rats.
Journal: European journal of clinical investigation 20040401
Title: Implantation of tumoral XC cells induces chronic, endothelin-dependent, thermal hyperalgesia in mice.
Journal: Cellular and molecular neurobiology 20040401
Title: Endothelin causes contraction of human esophageal muscularis mucosae through interaction with both ETA and ETB receptors.
Journal: Regulatory peptides 20040315
Title: Mechanisms underlying diabetes enhancement of endothelin-1-induced contraction in rabbit basilar artery.
Journal: European journal of pharmacology 20040223
Title: Different role of endothelin ETA and ETB receptors and endothelial modulators in diabetes-induced hyperreactivity of the rabbit carotid artery to endothelin-1.
Journal: European journal of pharmacology 20040213
Title: The role of endothelin in mediating ischemia/hypoxia-induced atrial natriuretic peptide release.
Journal: Journal of cardiovascular pharmacology 20040201
Title: Endothelins contribute towards nociception induced by antigen in ovalbumin-sensitised mice.
Journal: British journal of pharmacology 20040201
Title: Role of oxidative stress and nitric oxide in regulation of spontaneous tone in aorta of DOCA-salt hypertensive rats.
Journal: British journal of pharmacology 20040201
Title: Inward current oscillation underlying tonic contraction caused via ETA receptors in pig detrusor smooth muscle.
Journal: American journal of physiology. Renal physiology 20040101
Title: In-vivo interaction of nitric oxide and endothelin.
Journal: Journal of hypertension 20040101
Title: Profibrotic effects of endothelin-1 via the ETA receptor in cultured human cardiac fibroblasts.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101
Title: Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels.
Journal: Circulation research 20031212
Title: Endothelin receptor blockade has an oxygen-saving effect in Dahl salt-sensitive rats with heart failure.
Journal: American journal of physiology. Heart and circulatory physiology 20031001
Title: Endothelin-A receptors mediate renal hemodynamic effects of exogenous Angiotensin II in humans.
Journal: Hypertension (Dallas, Tex. : 1979) 20031001
Title: [Involvement of endothelin in the proliferative effect of lysophosphatidic acid on vascular smooth muscle cells in rats].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20031001
Title: Cerebral angiogenesis and expression of VEGF after subarachnoid hemorrhage (SAH) in rats.
Journal: Brain research 20030815
Title: Reduction of nitrite production by endothelin-1 in isolated porcine ciliary processes.
Journal: Experimental eye research 20030801
Title: Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivo.
Journal: The American journal of pathology 20030801
Title: Actions of endothelin and corticotropin releasing factor in the guinea-pig ileum: no evidence for an interaction with capsaicin-sensitive neurons.
Journal: Neuropeptides 20030801
Title: Endothelin-1 is a potent regulator in vivo in vascular calcification and in vitro in calcification of vascular smooth muscle cells.
Journal: Peptides 20030801
Title: Dual role of endothelin-1 via ETA and ETB receptors in regulation of cardiac contractile function in mice.
Journal: American journal of physiology. Heart and circulatory physiology 20030701
Title: Endothelin-1 and vascular tone in subjects with atherogenic risk factors.
Journal: Hypertension (Dallas, Tex. : 1979) 20030701
Title: Endothelin-1 inhibits TNF alpha-induced iNOS expression in 3T3-F442A adipocytes.
Journal: British journal of pharmacology 20030701
Title: Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin.
Journal: The Journal of physiology 20030615
Title: Hemodynamic and proinflammatory actions of endothelin-1 in guinea pig small intestine submucosal microcirculation.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20030601
Title: Role of endothelin ETA and ETB receptors in the guinea-pig urinary bladder contraction.
Journal: European journal of pharmacology 20030530
Title: Endothelin ET(A) but not ET(B) receptors mediate contraction of common bile duct.
Journal: Regulatory peptides 20030515
Title: Antiapoptotic effect of endothelin-1 in rat cardiomyocytes in vitro.
Journal: Hypertension (Dallas, Tex. : 1979) 20030501
Title: Regulation of human retinal blood flow by endothelin-1.
Journal: Experimental eye research 20030501
Title: Developmental changes in the functional, biochemical and molecular properties of rat bladder endothelin receptors.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030501
Title: Pharmacological characterization of TA-0201, an endothelin receptor antagonist, with recombinant and human prostate endothelin receptors.
Journal: European journal of pharmacology 20030425
Title: Endothelin receptor antagonists restore morphine analgesia in morphine tolerant rats.
Journal: Peptides 20030401
Title: Binding of a new bioactive 31-amino-acid endothelin-1 to an endothelin ET(B) or ET(B)-like receptor in porcine lungs.
Journal: European journal of pharmacology 20030328
Title: Will endothelin receptor antagonists have a role in heart failure?
Journal: The Medical clinics of North America 20030301
Title: Endothelin-1 stimulated capacitative Ca2+ entry through ET(A) receptors of a rat brain-derived type-1 astrocyte cell line, IA-1g1.
Journal: Cellular signalling 20030201
Title: Role of endothelin-1 in choroidal blood flow regulation during isometric exercise in healthy humans.
Journal: Investigative ophthalmology & visual science 20030201
Title: Effect of endothelin-1 (1-31) on the renal resistance vessels.
Journal: The journal of medical investigation : JMI 20030201
Title: ETA, mixed ETA/ETB receptor antagonists, and protein kinase C inhibitor prevent acute hypoxic pulmonary vasoconstriction: influence of potassium channels.
Journal: Journal of cardiovascular pharmacology 20030101
Title: Endothelin receptor blockade lowers plasma aldosterone levels via different mechanisms in primary aldosteronism and high-to-normal renin hypertension.
Journal: Cardiovascular research 20030101
Title: Role of K+ATP channels, endothelin A receptors, and effect of angiotensin II on blood flow in oral tissues.
Journal: Journal of dental research 20030101
Title: Et-A receptor antagonist BQ123 prevents radiocontrast media-induced renal medullary hypoxia.
Journal: Acta radiologica (Stockholm, Sweden : 1987) 20030101
Title: Endothelin ET A- and ET B-receptor-mediated inhibition of noradrenaline release from isolated rat stomach.
Journal: Journal of pharmacological sciences 20030101
Title: Endothelin-1 increases calcium and attenuates renin gene expression in As4.1 cells.
Journal: American journal of physiology. Heart and circulatory physiology 20021201
Title: Insulin sensitivity and big ET-1 conversion to ET-1 after ETA- or ETB-receptor blockade in humans.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20021201
Title: Endothelin-1-induced vasospasms of spiral modiolar artery are mediated by rho-kinase-induced Ca(2+) sensitization of contractile apparatus and reversed by calcitonin gene-related Peptide.
Journal: Stroke 20021201
Title: Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Abeta protein.
Journal: Journal of Alzheimer's disease : JAD 20021201
Title: Role of endothelin type B receptor in NO/cGMP signaling pathway in rat median eminence.
Journal: Cellular and molecular neurobiology 20021201
Title: Mechanism of endothelin-1-induced cytosolic Ca(2+) mobility in cultured H9c2 myocardiac ventricular cells.
Journal: Cellular signalling 20021001
Title: Endothelin-induced modulation of neuropeptide Y and norepinephrine release from the rat mesenteric bed.
Journal: American journal of physiology. Heart and circulatory physiology 20021001
Title: Increased activity of endogenous endothelin in patients with type II diabetes mellitus.
Journal: Circulation 20021001
Title: Different contractile effects of alpha1- and alpha2-adrenergic agonists on horse isolated common digital artery smooth muscle ring preparations in vitro.
Journal: Pharmacological research 20021001
Title: Potentiation of morphine analgesia by BQ123, an endothelin antagonist.
Journal: Peptides 20021001
Title: The vascular endothelin system is not overactive in normotensive hemodialysis patients.
Journal: Kidney international 20020901
Title: Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors.
Journal: European journal of immunology 20020901
Title: Involvement of endothelin-1 and its receptors in PGF2alpha-induced luteolysis in the rat.
Journal: Molecular reproduction and development 20020901
Title: Inhibitory activity on binding of specific ligands to the human angiotensin II AT(1) and endothelin 1 ET(A) receptors: bioactive benzo[c]phenanthridine alkaloids from the root of Bocconia frutescens.
Journal: Planta medica 20020901
Title: Possible mechanism of endothelin-induced Ca2+ mobility in A7r5 cultured vascular smooth muscle cells.
Journal: The Kaohsiung journal of medical sciences 20020901
Title: Enhanced vasoconstriction to endothelin-1, angiotensin II and noradrenaline in carriers of the GNB3 825T allele in the skin microcirculation.
Journal: Pharmacogenetics 20020801
Title: Forearm vasoconstriction to endothelin-1 is impaired, but constriction to sarafotoxin 6c and vasodilatation to BQ-123 unaltered, in patients with essential hypertension.
Journal: Clinical science (London, England : 1979) 20020801
Title: Endothelin-1 (1-31) induces a thiorphan-sensitive release of eicosanoids via ET(B) receptors in the guinea pig perfused lung.
Journal: Clinical science (London, England : 1979) 20020801
Title: Modulation of ET(B) receptor-induced arginine-vasopressin secretion by N-methyl-D-aspartate (NMDA) and gamma-aminobutyric acid (GABA)-dependent mechanisms in hypothalamo-neurohypophysial explants.
Journal: Clinical science (London, England : 1979) 20020801
Title: Differential vasoactive response to endothelin receptor antagonists and prostacyclin in patients with severe pulmonary hypertension.
Journal: Clinical science (London, England : 1979) 20020801
Title: Impact of parainfluenza-3 virus infection on endothelin receptor density and function in guinea pig airways.
Journal: Clinical science (London, England : 1979) 20020801
Title: Role of endothelin receptors in the hypertensive state of kinin B(2) knockout mice subjected to a high-salt diet.
Journal: Clinical science (London, England : 1979) 20020801
Title: Reduction of endothelin-1 binding and inhibition of endothelin-1-mediated detrusor contraction by naftidrofuryl.
Journal: Clinical science (London, England : 1979) 20020801
Title: Altered mitogen-activated protein kinase activation in vascular smooth muscle cells from spontaneously hypertensive rats.
Journal: Clinical and experimental pharmacology & physiology 20020701
Title: Mental stress induces prolonged endothelial dysfunction via endothelin-A receptors.
Journal: Circulation 20020618
Title: International Union of Pharmacology. XXIX. Update on endothelin receptor nomenclature.
Journal: Pharmacological reviews 20020601
Title: Action of the endothelin receptor (ETA) antagonist BQ-123 on forearm blood flow in young normotensive subjects.
Journal: Clinical science (London, England : 1979) 20020601
Title: Hyperglycemia exaggerates ischemia-reperfusion-induced cardiomyocyte injury: reversal with endothelin antagonism.
Journal: The Journal of thoracic and cardiovascular surgery 20020601
Title: Pronatriuretic peptide is a sensitive marker of the endocrine function of teleost heart.
Journal: American journal of physiology. Endocrinology and metabolism 20020401
Title: Endothelin ETA receptor-subtype specific antagonism does not mitigate the acute systemic or renal effects of exogenous angiotensin II in humans.
Journal: European journal of clinical investigation 20020401
Title: Endothelin blockade potentiates endothelial protective effects of ACE inhibitors in saphenous veins.
Journal: The Annals of thoracic surgery 20020401
Title: A novel bioactive 31-amino acid ET-1 peptide stimulates eosinophil recruitment and increases the levels of eotaxin and IL-5.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020401
Title: Endothelin-1 binding to endothelin receptors in the rat anterior pituitary gland: possible formation of an ETA-ETB receptor heterodimer.
Journal: Cellular and molecular neurobiology 20020401
Title: Endothelin-A receptors and NO mediate decrease in arterial pressure during recovery from restraint.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020301
Title: Endothelin-1 inhibits endothelium-dependent vasodilatation in the human forearm: reversal by ETA receptor blockade in patients with atherosclerosis.
Journal: Clinical science (London, England : 1979) 20020301
Title: Stimulation of catecholamine biosynthesis via the protein kinase C pathway by endothelin-1 in PC12 rat pheochromocytoma cells.
Journal: Biochemical pharmacology 20020301
Title: Endothelin-3 induces both human and opossum gallbladder contraction mediated mainly by endothelin-B receptor subtype in vitro.
Journal: Journal of gastroenterology and hepatology 20020301
Title: Endothelial modulation of skeletal muscle blood flow and VO(2) during low- and high-intensity contractions.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020201
Title: Improved endothelium-dependent vasodilation after blockade of endothelin receptors in patients with essential hypertension.
Journal: Circulation 20020129
Title: Endothelin in the mechanism of endothelial injury and neutrophil adhesion in the post-ischemic guinea-pig heart.
Journal: European journal of pharmacology 20020102
Title: Endothelin-1[1-31]: a novel autocrine-paracrine regulator of human adrenal cortex secretion and growth.
Journal: The Journal of clinical endocrinology and metabolism 20020101
Title: Endothelin-1 activates ET(A) receptors to increase intracellular calcium in model sensory neurons.
Journal: Neuroreport 20011204
Title: Coronary vasodilation and improvement in endothelial dysfunction with endothelin ET(A) receptor blockade.
Journal: Circulation research 20011123
Title: Myocardial contractile responsiveness to endothelin-1 in the post-infarction rat model of heart failure: effects of chronic quinapril.
Journal: Journal of molecular and cellular cardiology 20011101
Title: Rationale and perspective of endothelin-1 antagonism in acute heart failure.
Journal: Journal of cardiovascular pharmacology 20011101
Title: Autocrine regulation of prolactin secretion by endothelins: a permissive role for estradiol.
Journal: Endocrine 20011101
Title: Endothelin-1 induces contraction of human and Australian possum gallbladder in vitro.
Journal: Regulatory peptides 20011015
Title: Endothelin receptor blockade and nitric oxide bioactivity.
Journal: Cardiovascular research 20011001
Title: [Down-regulation of ETA receptor of vascular smooth muscle cells by 17 beta-estradiol].
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20011001
Title: Role of endothelin-1 in the active constriction of human atherosclerotic coronary arteries.
Journal: Circulation 20010904
Title: Endothelin-A receptor antagonist inhibits angiotensin II and noradrenaline in man.
Journal: British journal of clinical pharmacology 20010801
Title: Differential desensitization of Ca2+ mobilization and vasoconstriction by ET(A) receptors in the gerbil spiral modiolar artery.
Journal: The Journal of membrane biology 20010801
Title: Endothelin mediates some of the renal actions of acutely administered angiotensin II.
Journal: Hypertension (Dallas, Tex. : 1979) 20010701
Title: Factors involved in the time course of response to acetylcholine in mesenteric arteries from spontaneously hypertensive rats.
Journal: European journal of pharmacology 20010629
Title: Endothelin-1 mediates prostaglandin F(2alpha)-induced luteal regression in the ewe.
Journal: Biology of reproduction 20010601
Title: Endothelium-dependent relaxation in response to low concentrations of bradykinin is enhanced by phosphoramidon, bosentan and BQ-123 in bovine coronary arteries in vitro.
Journal: Japanese journal of pharmacology 20010601
Title: Paradoxically enhanced endothelin-B receptor-mediated vasoconstriction in conscious old monkeys.
Journal: Circulation 20010515
Title: Functional and biochemical evidence for capsaicin-induced neural endothelin release in isolated working rat heart.
Journal: European journal of pharmacology 20010511
Title: A novel pharmacological action of ET-1 to prevent the cytotoxicity of doxorubicin in cardiomyocytes.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010501
Title: Caged and clustered structures of endothelin inhibitor BQ123, cyclo(-D-Trp-D-Asp--Pro-D-Val-Leu-)-Na+, forming five and six coordination bonds between sodium ions and peptides.
Journal: Acta crystallographica. Section D, Biological crystallography 20010501
Title: The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm.
Journal: British journal of pharmacology 20010501
Title: Endothelin receptor antagonists in congestive heart failure: a new therapeutic principle for the future?
Journal: Journal of the American College of Cardiology 20010501
Title: Pulmonary adrenomedullin counteracts deterioration of coronary flow and myocardial performance evoked by pulmonary endothelins in experimental acute respiratory distress syndrome.
Journal: Critical care medicine 20010501
Title: Endothelin receptors in human and guinea-pig gallbladder muscle.
Journal: Regulatory peptides 20010420
Title: Intravasal peroxynitrite generation causes dysfunction in the isolated perfused rat lung via endothelin.
Journal: The Journal of pharmacology and experimental therapeutics 20010401
Title: Endothelin-1 induces vasoconstriction on portal-systemic collaterals of portal hypertensive rats.
Journal: Hepatology (Baltimore, Md.) 20010401
Title: Effect of the blood substitute diaspirin crosslinked hemoglobin in rat mesenteric and human radial collateral arteries.
Journal: Journal of cardiovascular pharmacology 20010401
Title: Effects of endothelin-1 and nitric oxide on proliferation of cultured guinea pig bronchial smooth muscle cells.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010401
Title: Signaling pathways involved in the A and B receptor-mediated cortisol secretagogue effect of endothelins in the human adrenal cortex.
Journal: International journal of molecular medicine 20010301
Title: Endothelin receptor blockade inhibits proliferation of Kaposi's sarcoma cells.
Journal: The American journal of pathology 20010301
Title: Inositolphosphate formation in thoracic and abdominal rat aorta following Gq/11-coupled receptor stimulation.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010301
Title: Augmentation of endothelial function by endothelin antagonism in human saphenous vein conduits.
Journal: Journal of neurosurgery 20010201
Title: Endothelin antagonism uncovers insulin-mediated vasorelaxation in vitro and in vivo.
Journal: Hypertension (Dallas, Tex. : 1979) 20010201
Title: Design, syntheses, and structure-activity relationships of indan derivatives as endothelin antagonists; new lead generation of non-peptidic antagonist from peptidic leads.
Journal: Bioorganic & medicinal chemistry 20010201
Title: Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells.
Journal: European journal of pharmacology 20010105
Title: Endothelin receptor blockade improves endothelial function in human internal mammary arteries.
Journal: Cardiovascular research 20010101
Title: A N-terminal PTHrP peptide fragment void of a PTH/PTHrP-receptor binding domain activates cardiac ET(A) receptors.
Journal: British journal of pharmacology 20010101
Title: Contribution of angiotensin II, endothelin 1 and the endothelium to the slow inotropic response to stretch in ferret papillary muscle.
Journal: Pflugers Archiv : European journal of physiology 20010101
Title: Bone blood flow and vascular reactivity.
Journal: Cells, tissues, organs 20010101
Title: Allosteric inhibition of endothelin ETA receptors by 3, 5-dibromosalicylic acid.
Journal: Molecular pharmacology 20001201
Title: Location of alkali metal binding sites in endothelin A selective receptor antagonists, cyclo(D-Trp-D-Asp-Pro-D-Val-Leu) and cyclo(D-Trp-D-Asp-Pro-D-Ile-Leu), from multistep collisionally activated decompositions.
Journal: Journal of mass spectrometry : JMS 20000201
Title: Angiotensin II receptor blockade unmasks a depressor response to endothelin antagonists in rats.
Journal: Fundamental & clinical pharmacology 20000101
Title: Suc-[Glu9,Ala11,15]-endothelin-1 (8-21), IRL 1620, identifies two populations of ET(B) receptors in guinea-pig bronchus.
Journal: British journal of pharmacology 19990701
Title: Novel sodium binding properties of some cyclopentapeptide endothelin A selective receptor antagonists: electrospray and fast-atom-bombardment mass spectrometric studies.
Journal: Biochemical and biophysical research communications 19990127
Title: Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy.
Journal: Cardiovascular research 19980901
Title: Role of endothelin in the human craniofacial morphogenesis.
Journal: Journal of craniofacial genetics and developmental biology 19980101
Title: Endothelin receptor-mediated Ca2+ mobilization and contraction in bovine oviductal arteries: comparison with noradrenaline and potassium.
Journal: General pharmacology 19971001
Title: Endothelin ETA receptors subtype mediates phosphoinositide hydrolysis in adrenal medulla.
Journal: Archives of physiology and biochemistry 19970901
Title: Excitatory gastric motor and cardiovascular effects of endothelins in the dorsal vagal complex are mediated through ET(A) receptors.
Journal: The Journal of pharmacology and experimental therapeutics 19970801
Title: Rediscovering an endothelin antagonist (BQ-123): a self-deconvoluting cyclic pentapeptide library.
Journal: Journal of medicinal chemistry 19960913
Title: Endothelin-1 stimulates deoxyribonucleic acid synthesis and contraction in testicular peritubular myoid cells.
Journal: Biology of reproduction 19960301
Title: Endothelin-1 inhibits L-type Ca currents enhanced by isoproterenol in guinea-pig ventricular myocytes.
Journal: Pflugers Archiv : European journal of physiology 19960201
Title: Endothelin-induced nociception in mice: mediation by ETA and ETB receptors.
Journal: The Journal of pharmacology and experimental therapeutics 19960201
Title: Role of endothelin in the cardiovascular effects of diaspirin crosslinked and stroma reduced hemoglobin.
Journal: Critical care medicine 19960101
Title: The effect of endothelin-2 (ET-2) on migration and changes in cytosolic free calcium of neutrophils.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 19960101
Title: Endothelin acts as a paracrine regulator of stretch-induced atrial natriuretic peptide release.
Journal: The American journal of physiology 19951101
Title: Structure-activity relationships of cyclic pentapeptide endothelin A receptor antagonists.
Journal: Journal of medicinal chemistry 19951013
Title: [Demonstration of a vasopressor role of endogenous endothelin after inhibition of nitric oxide synthesis in rats].
Journal: Archives des maladies du coeur et des vaisseaux 19950801
Title: ETA receptor-mediated constrictor responses to endothelin peptides in human blood vessels in vitro.
Journal: British journal of pharmacology 19950501
Title: Nonpeptide endothelin receptor antagonists: IV. Identification of receptors in rabbit colonic mucosa and smooth muscle and correlation with physiological effects.
Journal: The Journal of pharmacology and experimental therapeutics 19950301
Title: [3H]BQ-123, a highly specific and reversible radioligand for the endothelin ETA receptor subtype.
Journal: European journal of pharmacology 19950214
Title: In vivo evidence of an endothelin-induced vasopressor tone after inhibition of nitric oxide synthesis in rats.
Journal: Circulation 19950201
Title: Characterization of endothelin-1-induced vascular effects in the rat heart by using endothelin receptor antagonists.
Journal: European journal of pharmacology 19941212
Title: Solvent effects on the conformation of cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu-). An NMR spectroscopy and molecular modeling study.
Journal: International journal of peptide and protein research 19940501
Title: Mutational analysis of human endothelin receptors ETA and ETB identification of regions involved in the selectivity for endothelin 3 or cyclo-(D-Trp-D-Asp-Pro-D-Val-Leu).
Journal: European journal of biochemistry 19940501
Title: Differential blockade of the renal vasoconstrictor and diuretic responses to endothelin-1 by endothelin antagonist.
Journal: Clinical and experimental pharmacology & physiology 19940401
Title: Characterization of iris sphincter smooth muscle endothelin receptor subtypes which are coupled to cyclic AMP formation and polyphosphoinositide hydrolysis.
Journal: The Journal of pharmacology and experimental therapeutics 19940301
Title: [125I]-PD151242: a selective radioligand for human ETA receptors.
Journal: British journal of pharmacology 19940101
Title: Reversal of subarachnoid hemorrhage-induced vasoconstriction with an endothelin receptor antagonist.
Journal: Neurosurgery 19940101
Title: A conformational study by 1H NMR of a cyclic pentapeptide antagonist of endothelin.
Journal: Journal of medicinal chemistry 19930903
Title: Receptor externalization determines sustained contractile responses to endothelin-1 in the rat aorta.
Journal: The American journal of physiology 19930301
Title: BQ-123, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu), is a non-competitive antagonist of the actions of endothelin-1 in SK-N-MC human neuroblastoma cells.
Journal: Biochemical and biophysical research communications 19920415
Title: Solution conformation of a cyclic pentapeptide endothelin antagonist. Comparison of structures obtained from constrained dynamics and conformational search.
Journal: FEBS letters 19920316
Title: Conformational study of cyclo[D-Trp-D-Asp-Pro-D-Val-Leu], an endothelin-A receptor-selective antagonist.
Journal: FEBS letters 19920113
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Title: Zamora MA, et al. BQ123, an ETA receptor antagonist, inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol. 1993;9(4):429-433.
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Title: Erdogan H et al. The protective effects of endothelin-A receptor antagonist BQ-123 in pentylenetetrazole-induced seizure in rats. Hum Exp Toxicol, 2014 Oct, 33(10):1008-16.
