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Home Amines 1375466-18-4
1375466-18-4,MFCD30533691
Catalog No.:AA00A10G

1375466-18-4 | 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$46.00   $32.00
- +
2mg
98%
in stock  
$80.00   $56.00
- +
5mg
98%
in stock  
$112.00   $78.00
- +
10mg
98%
in stock  
$167.00   $117.00
- +
25mg
98%
in stock  
$300.00   $210.00
- +
50mg
98%
in stock  
$451.00   $316.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00A10G
Chemical Name:
2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
CAS Number:
1375466-18-4
Molecular Formula:
C17H19FN4O2
Molecular Weight:
330.3568
MDL Number:
MFCD30533691
SMILES:
ONC(=O)c1cnc(nc1)NC1(CCCCC1)c1cccc(c1)F
Properties
Computed Properties
 
Complexity:
423  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
XLogP3:
2.5  

Literature

Title: Veronick Benoy, et al. Development of Improved HDAC6 Inhibitors as Pharmacological Therapy for Axonal Charcot-Marie-Tooth Disease. Neurotherapeutics. 2017 Apr; 14(2): 417-428.

Title: Jeanine Jochems et al. Antidepressant-Like Properties of Novel HDAC6-Selective Inhibitors with Improved Brain Bioavailability. Neuropsychopharmacology. 2014 Jan; 39(2): 389-400.

Title: Severin Lechner, et al. Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target. Nat Chem Biol. 2022 Apr 28.

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SDS
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Tags:1375466-18-4 Molecular Formula|1375466-18-4 MDL|1375466-18-4 SMILES|1375466-18-4 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide