Home Amines 138516-31-1
138516-31-1,MFCD00909467
Catalog No.:AA00199Z

138516-31-1 | 1H-Pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-, acetate (1:1)

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1mg
≥98%
in stock  
$72.00   $50.00
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5mg
≥98%
in stock  
$262.00   $183.00
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10mg
≥98%
in stock  
$488.00   $341.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00199Z
Chemical Name:
1H-Pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-, acetate (1:1)
CAS Number:
138516-31-1
Molecular Formula:
C26H26N4O4
Molecular Weight:
458.5090
MDL Number:
MFCD00909467
SMILES:
CC(=O)O.NCCCn1cc(c2c1cccc2)C1=C(C(=O)NC1=O)c1cn(c2c1cccc2)C
Properties
Computed Properties
 
Complexity:
766  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  

Literature

Title: Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability.

Journal: American journal of respiratory cell and molecular biology 20111201

Title: Nrf2-mediated adaptive response to cadmium-induced toxicity involves protein kinase C delta in human 1321N1 astrocytoma cells.

Journal: Environmental toxicology and pharmacology 20110701

Title: Sex differences in the phosphorylation of mitochondrial proteins result in reduced production of reactive oxygen species and cardioprotection in females.

Journal: Circulation research 20100611

Title: Plasma protein kinase C (PKC)alpha as a biomarker for the diagnosis of cancers.

Journal: Carcinogenesis 20091101

Title: Structure of dystrophia myotonica protein kinase.

Journal: Protein science : a publication of the Protein Society 20090401

Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20071218

Title: Rottlerin causes pulmonary edema in vivo: a possible role for PKCdelta.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20071201

Title: Protein kinase Calpha mediates feedback inhibition of EGF receptor transactivation induced by Gq-coupled receptor agonists.

Journal: Cellular signalling 20070601

Title: Protein kinase C inhibition prevents upregulation of vascular ET(B) and 5-HT(1B) receptors and reverses cerebral blood flow reduction after subarachnoid haemorrhage in rats.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070101

Title: Mass-tag technology responding to intracellular signals as a novel assay system for the diagnosis of tumor.

Journal: Journal of the American Society for Mass Spectrometry 20070101

Title: Increase of Fas-induced apoptosis by inhibition of extracellular phosphorylation of Fas receptor in Jurkat cell line.

Journal: Apoptosis : an international journal on programmed cell death 20060701

Title: Effects of protein kinase inhibitors on the in vitro growth of Babesia bovis.

Journal: Parasitology 20060601

Title: Involvement of protein kinases on the upregulation of endothelin receptors in rat basilar and mesenteric arteries.

Journal: Experimental biology and medicine (Maywood, N.J.) 20060401

Title: Different signaling pathways involved in glucose- and cell swelling-induced insulin secretion by rat pancreatic islets in vitro.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101

Title: Negative regulation of phosphatidylinositol 3-kinase and Akt signalling pathway by PKC.

Journal: Cellular signalling 20030101

Title: Protein kinase mediated upregulation of endothelin A, endothelin B and 5-hydroxytryptamine 1B/1D receptors during organ culture in rat basilar artery.

Journal: British journal of pharmacology 20020901

Title: Bisindolylmaleimide VIII enhances DR5-mediated apoptosis through the MKK4/JNK/p38 kinase and the mitochondrial pathways.

Journal: The Journal of biological chemistry 20020809

Title: Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C.

Journal: The Biochemical journal 19930901

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Tags:138516-31-1 Molecular Formula|138516-31-1 MDL|138516-31-1 SMILES|138516-31-1 1H-Pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-, acetate (1:1)