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Home Amines 1391426-22-4
1391426-22-4,MFCD28127224
Catalog No.:AA001AB0

1391426-22-4 | N1-(7-Chloroquinolin-4-yl)-N2-(2-((7-chloroquinolin-4-yl)amino)ethyl)-N2-methylethane-1,2-diamine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
95%
1 week  
$98.00   $68.00
- +
10mg
95%
1 week  
$115.00   $80.00
- +
25mg
95%
1 week  
$149.00   $104.00
- +
50mg
95%
1 week  
$200.00   $140.00
- +
100mg
95%
1 week  
$314.00   $220.00
- +
200mg
95%
1 week  
$519.00   $364.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001AB0
Chemical Name:
N1-(7-Chloroquinolin-4-yl)-N2-(2-((7-chloroquinolin-4-yl)amino)ethyl)-N2-methylethane-1,2-diamine
CAS Number:
1391426-22-4
Molecular Formula:
C23H23Cl2N5
Molecular Weight:
440.3682
MDL Number:
MFCD28127224
SMILES:
CN(CCNc1ccnc2c1ccc(c2)Cl)CCNc1ccnc2c1ccc(c2)Cl
Properties
Computed Properties
 
Complexity:
480  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  
XLogP3:
5.4  

Downstream Synthesis Route

[1]Patent:WO2012/149186,2012,A2.Locationinpatent:Page/Pagecolumn33;34

[2]Patent:WO2016/22956,2016,A1.Locationinpatent:Page/Pagecolumn30;31

[1]CurrentPatentAssignee:UNIVERSITYOFPENNSYLVANIA-WO2012/149186,2012,A2Locationinpatent:Page/Pagecolumn34

[2]CurrentPatentAssignee:UNIVERSITYOFPENNSYLVANIA-WO2016/22956,2016,A1Locationinpatent:Page/Pagecolumn31;32

[1]Sakata,Yosuke;Yabunaka,Kosuke;Kobayashi,Yuko;Omiya,Hirohisa;Umezawa,Naoki;Kim,Hye-Sook;Wataya,Yusuke;Tomita,Yoshimi;Hisamatsu,Yosuke;Kato,Nobuki;Yagi,Hirokazu;Satoh,Tadashi;Kato,Koichi;Ishikawa,Haruto;Higuchi,Tsunehiko[ACSMedicinalChemistryLetters,2018,vol.9,#10,p.980-985]

Literature

Title: Lys05: a new lysosomal autophagy inhibitor.

Journal: Autophagy 20120901

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SDS
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Tags:1391426-22-4 Molecular Formula|1391426-22-4 MDL|1391426-22-4 SMILES|1391426-22-4 N1-(7-Chloroquinolin-4-yl)-N2-(2-((7-chloroquinolin-4-yl)amino)ethyl)-N2-methylethane-1,2-diamine