Name: Name:7-Chloro-4-piperazin-1-yl-quinoline
Brand: AABLOCKS
SKU: AA003NBS
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA003NBS

Chemical Name: 7-Chloro-4-piperazin-1-yl-quinoline

CAS Number: 837-52-5

Molecular Formula: C13H14ClN3

Molecular Weight: 247.7234

MDL Number: MFCD01476123

SMILES: Clc1ccc2c(c1)nccc2N1CCNCC1

Properties

BP: 433.5°C at 760 mmHg

Form: Solid

MP: 118 - 120 °C

Storage: Inert atmosphere;Room Temperature;

Complexity: 255

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 17

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.4

Literature fold

Title: Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor.

Journal: ACS medicinal chemistry letters20131010

Title: 7-Chloro-4-(piperazin-1-yl)quinoline.

Journal: Acta crystallographica. Section E, Structure reports online20120501

Title: Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies.

Journal: Journal of medicinal chemistry20110526

Title: Antiplasmodial and antitumor activity of dihydroartemisinin analogs derived via the aza-Michael addition reaction.

Journal: Bioorganic & medicinal chemistry letters20110515

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Quinolines and structurally related heterocycles as antimalarials.

Journal: European journal of medicinal chemistry20100801

Title: Synthesis of novel hybrid molecules from precursors with known antiparasitic activity.

Journal: Molecules (Basel, Switzerland)20090409

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Aida M Abd El-Sattar El-Azzouny, et al. Structural and biological survey of 7-chloro-4-(piperazin-1-yl)quinoline and its derivatives. Drug Dev Res. 2020 Nov;81(7):786-802.

837-52-5 | 7-Chloro-4-piperazin-1-yl-quinoline