Catalog No.:AA01OWIZ

1395946-75-4 | APX-115

Name: Name:APX-115
Brand: AABLOCKS
SKU: AA01OWIZ
Availability: InStock
Rating: 90 (10 reviews)

Pack Size

Purity

Availability

Price(USD)

Quantity

1mg

95%

1 week

$116.00 $81.00

- +

5mg

95%

1 week

$197.00 $138.00

- +

10mg

95%

1 week

$283.00 $198.00

- +

25mg

98%

1 week

$413.00 $289.00

- +

50mg

98%

1 week

$702.00 $492.00

- +

100mg

95%

1 week

$1,062.00 $744.00

- +

500mg

95%

1 week

$2,103.00 $1,472.00

- +

Technical Information
Properties
Downstream Synthesis Route
Literature
Request for Quotation
Download SDS

Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA01OWIZ

Chemical Name:

APX-115

CAS Number:

1395946-75-4

Molecular Formula:

C17H18ClN3O

Molecular Weight:

315.7973

MDL Number:

MFCD32201051

SMILES:

CCCc1c(nn(c1O)c1ccccn1)c1ccccc1.Cl

Properties

Downstream Synthesis Route

1270084-92-8

1-(pyridin-2-yl)-3-phenyl-4-propyl-1H-pyrazol-5-olhydrogenchloride

[1]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-EP2682392,2014,A2Locationinpatent:Paragraph0085

[2]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-US2014/88152,2014,A1Locationinpatent:Paragraph0537-0540

[3]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-US2014/128418,2014,A1Locationinpatent:Paragraph0200;0201;0202

[4]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-EP2889032,2015,A1Locationinpatent:Paragraph0042;0043;0044

[5]CurrentPatentAssignee:APTABIOTHERAPEUTICSINC-KR101856444,2018,B1Locationinpatent:Paragraph0096-0097;0101-0102

[6]CurrentPatentAssignee:APTABIOTHERAPEUTICSINC-WO2019/88444,2019,A1Locationinpatent:Paragraph94-97

Literature

Title: Kwon G, et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 2017 Jun 16;8(43):74217-74232.

Title: Cha JJ, et al. APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury. Lab Invest. 2017 Apr;97(4):419-431.

Quotation Request

Company Name:

Contact Person:

Email:

Quantity Required:

Country:

Additional Info:

SDS