+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
1415379-56-4,MFCD29767874
Catalog No.:AA00A0EK

1415379-56-4 | T807

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
97%
in stock  
$30.00   $21.00
- +
25mg
97%
in stock  
$75.00   $53.00
- +
250mg
97%
in stock  
$335.00   $234.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00A0EK
Chemical Name:
T807
CAS Number:
1415379-56-4
Molecular Formula:
C16H10FN3
Molecular Weight:
263.2691
MDL Number:
MFCD29767874
SMILES:
Fc1ccc(cn1)c1ccc2c(c1)[nH]c1c2cncc1
Properties
Computed Properties
 
Complexity:
351  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ELILILLY&CO-WO2015/47902,2015,A1Locationinpatent:Page/Pagecolumn19

89364-04-5   
7-(6-fluoropyridin-3-yl)-5H-pyrido4,3-bindole 

[1]BioorganicandMedicinalChemistryLetters,2015,vol.25,p.2953-2957

[2]JournalofMedicinalChemistry,2016,vol.59,p.4778-4789

[3]Patent:US2018/125821,2018,A1

[4]PLoSONE,2019,vol.14

[1]Gao,Mingzhang;Wang,Min;Zheng,Qi-Huang[BioorganicandMedicinalChemistryLetters,2015,vol.25,#15,p.2953-2957]

[2]Walji,AbbasM.;Hostetler,EricD.;Selnick,Harold;Zeng,Zhizhen;Miller,Patricia;Bennacef,Idriss;Salinas,Cristian;Connolly,Brett;Gantert,Liza;Holahan,Marie;O'Malley,Stacey;Purcell,Mona;Riffel,Kerry;Li,Jing;Balsells,Jaume;Obrien,JulieA.;Melquist,Stacey;Soriano,Aileen;Zhang,Xiaoping;Ogawa,Aimie;Xu,Serena;Joshi,Elizabeth;DellaRocca,Joseph;Hess,FredJ.;Schachter,Joel;Hesk,David;Schenk,David;Struyk,Arie;Babaoglu,Kerim;Lohith,TalakadG.;Wang,Yaode;Yang,Kun;Fu,Jianmin;Evelhoch,JeffreyL.;Coleman,PaulJ.[JournalofMedicinalChemistry,2016,vol.59,#10,p.4778-4789]

[3]CurrentPatentAssignee:ARVINAS-US2018/125821,2018,A1

[4]CurrentPatentAssignee:ARVINAS-WO2021/11913,2021,A1

1015460-59-9    351019-18-6   
7-(6-fluoropyridin-3-yl)-5H-pyrido4,3-bindole 

[1]Patent:US2018/125821,2018,A1

[2]BioorganicandMedicinalChemistryLetters,2015,vol.25,p.2953-2957

[3]JournalofMedicinalChemistry,2016,vol.59,p.4778-4789

[4]PLoSONE,2019,vol.14

[1]Gao,Mingzhang;Wang,Min;Zheng,Qi-Huang[BioorganicandMedicinalChemistryLetters,2015,vol.25,#15,p.2953-2957]

[2]Walji,AbbasM.;Hostetler,EricD.;Selnick,Harold;Zeng,Zhizhen;Miller,Patricia;Bennacef,Idriss;Salinas,Cristian;Connolly,Brett;Gantert,Liza;Holahan,Marie;O'Malley,Stacey;Purcell,Mona;Riffel,Kerry;Li,Jing;Balsells,Jaume;Obrien,JulieA.;Melquist,Stacey;Soriano,Aileen;Zhang,Xiaoping;Ogawa,Aimie;Xu,Serena;Joshi,Elizabeth;DellaRocca,Joseph;Hess,FredJ.;Schachter,Joel;Hesk,David;Schenk,David;Struyk,Arie;Babaoglu,Kerim;Lohith,TalakadG.;Wang,Yaode;Yang,Kun;Fu,Jianmin;Evelhoch,JeffreyL.;Coleman,PaulJ.[JournalofMedicinalChemistry,2016,vol.59,#10,p.4778-4789]

[3]Huang,Ya-Yao;Chiu,Ming-Jang;Yen,Ruoh-Fang;Tsai,Chia-Ling;Hsieh,Hao-Yu;Chiu,Ching-Hung;Wu,Chi-Han;Hsin,Ling-Wei;Tzen,Kai-Yuan;Cheng,Cheng-Yi;Ma,Kuo-Hsing;Shiue,Chyng-Yann[PLoSONE,2019,vol.14,#7]

[4]CurrentPatentAssignee:ARVINAS-US2018/125821,2018,A1

[5]CurrentPatentAssignee:KOREAINSTITUTEOFSCIENCEANDTECHNOLOGY-KR2020/142215,2020,A

[6]CurrentPatentAssignee:ARVINAS-WO2021/11913,2021,A1

Literature

Title: Characterization of tau positron emission tomography tracer [(18)F]AV-1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association 20161101

Title: Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue.

Journal: Annals of neurology 20151101

Title: Xia CF, et al. [(18)FT807, a novel tau positron emission tomography imaging agent for Alzheimer's disease. Alzheimers Dement. 2013 Nov;9(6):666-76.

Title: Marquié M, et al. Validating novel tau positron emission tomography tracer [F-18-AV-1451 (T807) on postmortem brain tissue. Ann Neurol. 2015 Nov;78(5):787-800.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 1415379-56-4
Building Blocks
More >
Historical Records
1427083-36-0

1427083-36-0
Tags:1415379-56-4 Molecular Formula|1415379-56-4 MDL|1415379-56-4 SMILES|1415379-56-4 T807
Catalog No.: AA00A0EK
1415379-56-4,MFCD29767874
1415379-56-4 | T807
Pack Size： 5mg
Purity： 97%
in stock
$30.00 $21.00
Pack Size： 25mg
Purity： 97%
in stock
$75.00 $53.00
Pack Size： 250mg
Purity： 97%
in stock
$335.00 $234.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00A0EK
Chemical Name: T807
CAS Number: 1415379-56-4
Molecular Formula: C16H10FN3
Molecular Weight: 263.2691
MDL Number: MFCD29767874
SMILES: Fc1ccc(cn1)c1ccc2c(c1)[nH]c1c2cncc1
Properties
Complexity: 351  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 20  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 1  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.3  
Downstream Synthesis Route
1522052-31-8    1522051-90-6    1415379-56-4 

[1]CurrentPatentAssignee:ELILILLY&CO-WO2015/47902,2015,A1Locationinpatent:Page/Pagecolumn19

89364-04-5   
7-(6-fluoropyridin-3-yl)-5H-pyrido4,3-bindole 

[1]BioorganicandMedicinalChemistryLetters,2015,vol.25,p.2953-2957

[2]JournalofMedicinalChemistry,2016,vol.59,p.4778-4789

[3]Patent:US2018/125821,2018,A1

[4]PLoSONE,2019,vol.14

5467-74-3    1415379-56-4 

[1]Gao,Mingzhang;Wang,Min;Zheng,Qi-Huang[BioorganicandMedicinalChemistryLetters,2015,vol.25,#15,p.2953-2957]

[2]Walji,AbbasM.;Hostetler,EricD.;Selnick,Harold;Zeng,Zhizhen;Miller,Patricia;Bennacef,Idriss;Salinas,Cristian;Connolly,Brett;Gantert,Liza;Holahan,Marie;O'Malley,Stacey;Purcell,Mona;Riffel,Kerry;Li,Jing;Balsells,Jaume;Obrien,JulieA.;Melquist,Stacey;Soriano,Aileen;Zhang,Xiaoping;Ogawa,Aimie;Xu,Serena;Joshi,Elizabeth;DellaRocca,Joseph;Hess,FredJ.;Schachter,Joel;Hesk,David;Schenk,David;Struyk,Arie;Babaoglu,Kerim;Lohith,TalakadG.;Wang,Yaode;Yang,Kun;Fu,Jianmin;Evelhoch,JeffreyL.;Coleman,PaulJ.[JournalofMedicinalChemistry,2016,vol.59,#10,p.4778-4789]

[3]CurrentPatentAssignee:ARVINAS-US2018/125821,2018,A1

[4]CurrentPatentAssignee:ARVINAS-WO2021/11913,2021,A1

1015460-59-9    351019-18-6   
7-(6-fluoropyridin-3-yl)-5H-pyrido4,3-bindole 

[1]Patent:US2018/125821,2018,A1

[2]BioorganicandMedicinalChemistryLetters,2015,vol.25,p.2953-2957

[3]JournalofMedicinalChemistry,2016,vol.59,p.4778-4789

[4]PLoSONE,2019,vol.14

1415379-81-5    1415379-56-4 

[1]Gao,Mingzhang;Wang,Min;Zheng,Qi-Huang[BioorganicandMedicinalChemistryLetters,2015,vol.25,#15,p.2953-2957]

[2]Walji,AbbasM.;Hostetler,EricD.;Selnick,Harold;Zeng,Zhizhen;Miller,Patricia;Bennacef,Idriss;Salinas,Cristian;Connolly,Brett;Gantert,Liza;Holahan,Marie;O'Malley,Stacey;Purcell,Mona;Riffel,Kerry;Li,Jing;Balsells,Jaume;Obrien,JulieA.;Melquist,Stacey;Soriano,Aileen;Zhang,Xiaoping;Ogawa,Aimie;Xu,Serena;Joshi,Elizabeth;DellaRocca,Joseph;Hess,FredJ.;Schachter,Joel;Hesk,David;Schenk,David;Struyk,Arie;Babaoglu,Kerim;Lohith,TalakadG.;Wang,Yaode;Yang,Kun;Fu,Jianmin;Evelhoch,JeffreyL.;Coleman,PaulJ.[JournalofMedicinalChemistry,2016,vol.59,#10,p.4778-4789]

[3]Huang,Ya-Yao;Chiu,Ming-Jang;Yen,Ruoh-Fang;Tsai,Chia-Ling;Hsieh,Hao-Yu;Chiu,Ching-Hung;Wu,Chi-Han;Hsin,Ling-Wei;Tzen,Kai-Yuan;Cheng,Cheng-Yi;Ma,Kuo-Hsing;Shiue,Chyng-Yann[PLoSONE,2019,vol.14,#7]

[4]CurrentPatentAssignee:ARVINAS-US2018/125821,2018,A1

[5]CurrentPatentAssignee:KOREAINSTITUTEOFSCIENCEANDTECHNOLOGY-KR2020/142215,2020,A

[6]CurrentPatentAssignee:ARVINAS-WO2021/11913,2021,A1

Literature fold

Title: Characterization of tau positron emission tomography tracer [(18)F]AV-1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association20161101

Title: Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue.

Journal: Annals of neurology20151101

Title: Xia CF, et al. [(18)FT807, a novel tau positron emission tomography imaging agent for Alzheimer's disease. Alzheimers Dement. 2013 Nov;9(6):666-76.

Title: Marquié M, et al. Validating novel tau positron emission tomography tracer [F-18-AV-1451 (T807) on postmortem brain tissue. Ann Neurol. 2015 Nov;78(5):787-800.

Related Products of of 1415379-56-4
Building Blocks More >
130818-98-3
130818-98-3
3-(Piperidin-4-yl)oxazolidin-2-one hydrochloride
AA00A0UC | MFCD17014279
1432478-91-5
1432478-91-5
AM2233 azepane isomer
AA00A1CI
1236262-07-9
1236262-07-9
2-Amino-1-(2,3-dihydro-1H-indol-1-yl)-1-propanonehydrochloride
AA00A2BU | MFCD13562014
1257535-16-2
1257535-16-2
5-Bromo-3-(trifluoromethoxy)benzene-1,2-diamine
AA00A5HG | MFCD16628053
134855-88-2
134855-88-2
(R)-4-(1-Aminoethyl)phenol
AA00A8ER | MFCD03844647
1262412-64-5
1262412-64-5
tert-Butyl 3,3-difluoro-5-(hydroxymethyl)piperidine-1-carboxylate
AA00AA98 | MFCD16875553
152404-44-9
152404-44-9
4-BROMOPHENOL-2,3,5,6-D4
AA00AAYB | MFCD01861646
163847-77-6
163847-77-6
TAPI-1
AA00AB6R | MFCD02684280
172168-01-3
172168-01-3
Ethyl 3-(3,5-dichlorophenyl)-3-oxopropanoate
AA00ABHA | MFCD03424831
180977-34-8
180977-34-8
FTI 277 HYDROCHLORIDE
AA00ABL4 | MFCD28385886
Historical Records
1427083-36-0
1427083-36-0
Submit
© 2017 AA BLOCKS, INC. All rights reserved.