+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Indole and Oxindoles 1416990-08-3
1416990-08-3,MFCD31794971
Catalog No.:AA01JLS2

1416990-08-3 | 3-(5-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
97%
in stock  
$52.00   $36.00
- +
250mg
97%
in stock  
$94.00   $66.00
- +
1g
95%
in stock  
$366.00   $257.00
- +
5g
97%
in stock  
$828.00   $580.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01JLS2
Chemical Name:
3-(5-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione
CAS Number:
1416990-08-3
Molecular Formula:
C13H12N2O4
Molecular Weight:
260.2454
MDL Number:
MFCD31794971
SMILES:
O=C1CCC(C(=O)N1)N1Cc2c(C1=O)ccc(c2)O
Properties

Downstream Synthesis Route

[1]Ruchelman,AlexanderL.;Man,Hon-Wah;Zhang,Weihong;Chen,Roger;Capone,Lori;Kang,Jian;Parton,Anastasia;Corral,Laura;Schafer,PeterH.;Babusis,Darius;Moghaddam,MehranF.;Tang,Yang;Shirley,MichaelA.;Muller,GeorgeW.[BioorganicandMedicinalChemistryLetters,2013,vol.23,#1,p.360-365]

[1]Ruchelman,AlexanderL.;Man,Hon-Wah;Zhang,Weihong;Chen,Roger;Capone,Lori;Kang,Jian;Parton,Anastasia;Corral,Laura;Schafer,PeterH.;Babusis,Darius;Moghaddam,MehranF.;Tang,Yang;Shirley,MichaelA.;Muller,GeorgeW.[BioorganicandMedicinalChemistryLetters,2013,vol.23,#1,p.360-365]

[1]Ruchelman,AlexanderL.;Man,Hon-Wah;Zhang,Weihong;Chen,Roger;Capone,Lori;Kang,Jian;Parton,Anastasia;Corral,Laura;Schafer,PeterH.;Babusis,Darius;Moghaddam,MehranF.;Tang,Yang;Shirley,MichaelA.;Muller,GeorgeW.[BioorganicandMedicinalChemistryLetters,2013,vol.23,#1,p.360-365]

1416990-08-3   
C30H36ClN5O3 
 
N-((1r,3r)-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-4-(4-(5-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)oxy)pentyl)-1H-1,2,3-triazol-1-yl)benzamide 

[1]CurrentPatentAssignee:ARVINAS-US2018/99940,2018,A1Locationinpatent:Page/Pagecolumn93-94

1416990-08-3   
C29H35ClN6O5S 
 
N-((1r,3r)-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-6-(4-(5-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)oxy)pentyl)-1H-1,2,3-triazol-1-yl)nicotinamide 

[1]CurrentPatentAssignee:ARVINAS-US2018/99940,2018,A1Locationinpatent:Page/Pagecolumn119

Literature

Title: Jaime-Figueroa S, et al. Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties. 2020 Feb 1;30(3):126877.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1416990-08-3
1219177-18-0

1219177-18-0

 50-35-1

50-35-1

 2614-06-4

2614-06-4

 5054-59-1

5054-59-1

 64567-60-8

64567-60-8

 1061604-41-8

1061604-41-8
Building Blocks
More >
Tags:1416990-08-3 Molecular Formula|1416990-08-3 MDL|1416990-08-3 SMILES|1416990-08-3 3-(5-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione