Home Other Building Blocks 143621-35-6
143621-35-6,MFCD00924747
Catalog No.:AA007YMG

143621-35-6 | Triapine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$13.00   $9.00
- +
5mg
98%
in stock  
$29.00   $21.00
- +
10mg
98%
in stock  
$44.00   $31.00
- +
25mg
98%
in stock  
$73.00   $51.00
- +
50mg
98%
in stock  
$115.00   $81.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007YMG
Chemical Name:
Triapine
CAS Number:
143621-35-6
Molecular Formula:
C7H9N5S
Molecular Weight:
195.2449
MDL Number:
MFCD00924747
SMILES:
NC(=S)N/N=C/c1ncccc1N
NSC Number:
663249
Properties
Computed Properties
 
Complexity:
205  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
-0.2  

Literature

Title: Martin LK, et al. A dose escalation and pharmacodynamic study of Triapine and radiation in patients with locally advanced pancreas cancer. Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):e475-81.

Title: Yalowich JC, et al. The anticancer thiosemicarbazones Dp44mT and Triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα. Biochem Pharmacol. 2012 Jul 1;84(1):52-8.

Title: Whitnall M, et al. A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14901-6.

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SDS
Tags:143621-35-6 Molecular Formula|143621-35-6 MDL|143621-35-6 SMILES|143621-35-6 Triapine