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144217-65-2,MFCD00738763
Catalog No.:AA00ABQS

144217-65-2 | Yya-021

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Purity
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1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$136.00   $95.00
- +
10mg
≥98%
in stock  
$228.00   $159.00
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25mg
≥98%
in stock  
$509.00   $356.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ABQS
Chemical Name:
Yya-021
CAS Number:
144217-65-2
Molecular Formula:
C18H27N3O2
Molecular Weight:
317.4259
MDL Number:
MFCD00738763
SMILES:
Cc1ccc(cc1)NC(=O)C(=O)NC1CC(C)(C)NC(C1)(C)C
Properties
Computed Properties
 
Complexity:
435  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
2.5  

Literature

Title: CD4 mimics as HIV entry inhibitors: lead optimization studies of the aromatic substituents.

Journal: Bioorganic & medicinal chemistry 20130501

Title: Small molecular CD4 mimics as HIV entry inhibitors.

Journal: Bioorganic & medicinal chemistry 20111115

Title: CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist.

Journal: Bioorganic & medicinal chemistry letters 20101001

Title: Mizuguchi T, et al. A minimally cytotoxic CD4 mimic as an HIV entry inhibitor. Bioorg Med Chem Lett. 2016 Jan 15;26(2):397-400.

Title: Hashimoto C, et al. A CD4 mimic as an HIV entry inhibitor: pharmacokinetics. Bioorg Med Chem. 2013 Dec 15;21(24):7884-9.

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SDS
Tags:144217-65-2 Molecular Formula|144217-65-2 MDL|144217-65-2 SMILES|144217-65-2 Yya-021