Title: Structure-Based Design of a Small Molecule CD4-Antagonist with Broad Spectrum Anti-HIV-1 Activity.
Journal: Journal of medicinal chemistry 20150910
Title: CD4 mimics as HIV entry inhibitors: lead optimization studies of the aromatic substituents.
Journal: Bioorganic & medicinal chemistry 20130501
Title: Design, synthesis, and antiviral activity of entry inhibitors that target the CD4-binding site of HIV-1.
Journal: Journal of medicinal chemistry 20120524
Title: Small molecular CD4 mimics as HIV entry inhibitors.
Journal: Bioorganic & medicinal chemistry 20111115
Title: Enhanced dynamics of HIV gp120 glycoprotein by small molecule binding.
Journal: Biochemistry 20110517
Title: Some binding-related drug properties are dependent on thermodynamic signature.
Journal: Chemical biology & drug design 20110301
Title: Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening.
Journal: Bioorganic & medicinal chemistry 20110101
Title: CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist.
Journal: Bioorganic & medicinal chemistry letters 20101001
Title: Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120.
Journal: Biochemistry 20060912
Title: Zhao Q, Ma L, Jiang S, Lu H, Liu S, He Y, Strick N, Neamati N, Debnath AK.Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4.Virology. 2005 Sep 1;339(2):213-25.
Title: Schon A, et al. Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120. Biochemistry. 2006 Sep 12;45(36):10973-10980.
