Title: Gap junctional intercellular communication and endoplasmic reticulum stress regulate chronic cadmium exposure induced apoptosis in HK-2 cells.
Journal: Toxicology letters20180515
Title: Glycyrrhizin and glycyrrhetinic acid inhibits alpha-naphthyl isothiocyanate-induced liver injury and bile acid cycle disruption.
Journal: Toxicology20170701
Title: Methotrexate hepatotoxicity is associated with oxidative stress, and down-regulation of PPARγ and Nrf2: Protective effect of 18β-Glycyrrhetinic acid.
Journal: Chemico-biological interactions20170525
Title: 18β-Glycyrrhetinic acid suppresses TNF-α induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the Akt-dependent NF-κB pathway.
Journal: Toxicology in vitro : an international journal published in association with BIBRA20140801
Title: Purinergic signaling via P2Y receptors up-mediates IL-6 production by liver macrophages/Kupffer cells.
Journal: The Journal of toxicological sciences20140601
Title: Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: herb-drug interactions mediated via P-gp.
Journal: Toxicology and applied pharmacology20140301
Title: Anti-diabetic and anti-inflammatory effect of a novel selective 11β-HSD1 inhibitor in the diet-induced obese mice.
Journal: European journal of pharmacology20131205
Title: 18β-glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway.
Journal: Molecular and cellular biochemistry20121101
Title: The blood-brain barrier permeability of 18β-glycyrrhetinic acid, a major metabolite of glycyrrhizin in Glycyrrhiza root, a constituent of the traditional Japanese medicine yokukansan.
Journal: Cellular and molecular neurobiology20121001
Title: Myoendothelial coupling is unidirectional in guinea pig spiral modiolar arteries.
Journal: Microvascular research20120901
Title: Mitochondrial connexin 43 impacts on respiratory complex I activity and mitochondrial oxygen consumption.
Journal: Journal of cellular and molecular medicine20120801
Title: Laminin-111 stimulates proliferation of mouse embryonic stem cells through a reduction of gap junctional intercellular communication via RhoA-mediated Cx43 phosphorylation and dissociation of Cx43/ZO-1/drebrin complex.
Journal: Stem cells and development20120720
Title: Enhanced transdermal delivery of 18β-glycyrrhetic acid via elastic vesicles: in vitro and in vivo evaluation.
Journal: Drug development and industrial pharmacy20120701
Title: TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity.
Journal: American journal of physiology. Cell physiology20120615
Title: The anti-ulcer agent, irsogladine, increases insulin secretion by MIN6 cells.
Journal: European journal of pharmacology20120615
Title: 18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels.
Journal: Acta pharmacologica Sinica20120601
Title: 18β-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells.
Journal: Journal of cellular physiology20120501
Title: Gap junctions propagate opposite effects in normal and tumor testicular cells in response to cisplatin.
Journal: Cancer letters20120428
Title: 18β-Glycyrrhetinic acid inhibits adipogenic differentiation and stimulates lipolysis.
Journal: Biochemical and biophysical research communications20120420
Title: ERK acts in parallel to PKCδ to mediate the connexin43-dependent potentiation of Runx2 activity by FGF2 in MC3T3 osteoblasts.
Journal: American journal of physiology. Cell physiology20120401
Title: Inhibition of gap junction channel attenuates the migration of breast cancer cells.
Journal: Molecular biology reports20120301
Title: Effects of 18β-Glycyrrhetinic acid in hTNFtg mice - a model of rheumatoid arthritis.
Journal: Wiener klinische Wochenschrift20120301
Title: Antimycobacterial and synergistic effects of 18β-glycyrrhetinic acid or glycyrrhetinic acid-30-piperazine in combination with isoniazid, rifampicin or streptomycin against Mycobacterium bovis.
Journal: Phytotherapy research : PTR20120201
Title: Characterization of a novel oral glucocorticoid system and its possible role in disease.
Journal: Journal of dental research20120101
Title: Endothelium-derived relaxing factor-mediated vasodilation in mouse mesenteric vascular beds.
Journal: Journal of pharmacological sciences20120101
Title: Pharmacokinetic analysis of alpha and beta epimers of glycyrrhetinic acid in rat plasma: differences in singly and combined administrations.
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20120101
Title: 18α-glycyrrhetinic acid down-regulates expression of type I and III collagen via TGF-Β1/Smad signaling pathway in human and rat hepatic stellate cells.
Journal: International journal of medical sciences20120101
Title: A novel transdermal fomulation of 18β-glycyrrhetic acid with lysine for improving bioavailability and efficacy.
Journal: Skin pharmacology and physiology20120101
Title: Gap junctions contribute to astrocytic resistance against zinc toxicity.
Journal: Brain research bulletin20111125
Title: Disruption of gap junctions reduces biomarkers of decidualization and angiogenesis and increases inflammatory mediators in human endometrial stromal cell cultures.
Journal: Molecular and cellular endocrinology20110915
Title: 18α-glycyrrhetinic acid targets prostate cancer cells by down-regulating inflammation-related genes.
Journal: International journal of oncology20110901
Title: Therapeutic effects of connexin inhibitors on detrusor overactivity induced by bladder outlet obstruction in rats.
Journal: Urology20110801
Title: Inhibition of osteoblastic differentiation by warfarin and 18-α-glycyrrhetinic acid.
Journal: Archives of pharmacal research20110801
Title: Glycyrrhizic acid and 18β-glycyrrhetinic acid modulate lipopolysaccharide-induced inflammatory response by suppression of NF-κB through PI3K p110δ and p110γ inhibitions.
Journal: Journal of agricultural and food chemistry20110727
Title: 18β-Glycyrrhetinic acid derivatives induced mitochondrial-mediated apoptosis through reactive oxygen species-mediated p53 activation in NTUB1 cells.
Journal: Bioorganic & medicinal chemistry20110715
Title: 18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis.
Journal: Ocular immunology and inflammation20110601
Title: 18beta-glycyrrhetinic acid and glabridin prevent oxidative DNA fragmentation in UVB-irradiated human keratinocyte cultures.
Journal: Anticancer research20110601
Title: Chemopreventive potential of 18beta-glycyrrhetinic acid: an active constituent of liquorice, in 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis.
Journal: Pakistan journal of biological sciences : PJBS20110601
Title: Effects of connexin-mimetic peptides on perfusion pressure in response to phenylephrine in isolated, perfused rat kidneys.
Journal: Clinical and experimental nephrology20110401
Title: Design, synthesis, and sustained-release property of 1,3-cyclic propanyl phosphate ester of 18β-glycyrrhetinic acid.
Journal: Chemical biology & drug design20110301
Title: [Expression of 11β-hydroxysteroid dehydrogenase type 2 in lymphoblastic cells and its relationship with glucocorticoid sensitivity].
Journal: Zhongguo shi yan xue ye xue za zhi20110201
Title: Intercellular communication amplifies stressful effects in high-charge, high-energy (HZE) particle-irradiated human cells.
Journal: Journal of radiation research20110101
Title: Curative effect of 18β-glycyrrhetinic acid in experimental visceral leishmaniasis depends on phosphatase-dependent modulation of cellular MAP kinases.
Journal: PloS one20110101
Title: 18β-Glycyrrhetinic acid potentiates apoptotic effect of trichostatin A on human epithelial ovarian carcinoma cell lines.
Journal: European journal of pharmacology20101215
Title: Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20101208
Title: 18β-glycyrrhetinic acid inhibits periodontitis via glucocorticoid-independent nuclear factor-κB inactivation in interleukin-10-deficient mice.
Journal: Journal of periodontal research20101201
Title: Role of connexin 43 in the maintenance of spontaneous activity in the guinea pig prostate gland.
Journal: British journal of pharmacology20101201
Title: Cytoplasm and organelle transfer between mesenchymal multipotent stromal cells and renal tubular cells in co-culture.
Journal: Experimental cell research20100910
Title: Glycyrrhizic acid and 18beta-glycyrrhetinic acid inhibit inflammation via PI3K/Akt/GSK3beta signaling and glucocorticoid receptor activation.
Journal: Journal of agricultural and food chemistry20100811
Title: Connexin 43 hemichannel regulates H9c2 cell proliferation by modulating intracellular ATP and [Ca2+].
Journal: Acta biochimica et biophysica Sinica20100701
Title: Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts.
Journal: The Journal of biological chemistry20100312
Title: Gap junctions and memory: an investigation using a single trial discrimination avoidance task for the neonate chick.
Journal: Neurobiology of learning and memory20100201
Title: Glycyrrhizin and its metabolite 18 beta-glycyrrhetinic acid in glycyrrhiza, a constituent herb of yokukansan, ameliorate thiamine deficiency-induced dysfunction of glutamate transport in cultured rat cortical astrocytes.
Journal: European journal of pharmacology20100125
Title: 18Beta-glycyrrhetinic acid ameliorates acute Propionibacterium acnes-induced liver injury through inhibition of macrophage inflammatory protein-1alpha.
Journal: The Journal of biological chemistry20100108
Title: Mechanism underlying endothelium-dependent relaxation by 2-methylthio-ADP in monkey cerebral artery.
Journal: Journal of pharmacological sciences20100101
Title: Panax notoginseng saponins potentiate osteogenesis of bone marrow stromal cells by modulating gap junction intercellular communication activities.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20100101
Title: Role of connexin-43 hemichannels in the pathogenesis of Yersinia enterocolitica.
Journal: Veterinary journal (London, England : 1997)20091201
Title: Tramadol and flurbiprofen depress the cytotoxicity of cisplatin via their effects on gap junctions.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20090915
Title: Glycyrrhizin prevents 7-ketocholesterol toxicity against differentiated PC12 cells by suppressing mitochondrial membrane permeability change.
Journal: Neurochemical research20090801
Title: Direct formation of proteo-liposomes by in vitro synthesis and cellular cytosolic delivery with connexin-expressing liposomes.
Journal: Biomaterials20090801
Title: A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer.
Journal: Molecular cancer therapeutics20090801
Title: Infusion of gliotoxins or a gap junction blocker in the prelimbic cortex increases alcohol preference in Wistar rats.
Journal: Journal of psychopharmacology (Oxford, England)20090701
Title: Hypolipidemic activity of 18beta-glycyrrhetinic acid on streptozotocin-induced diabetic rats.
Journal: European journal of pharmacology20090610
Title: Effect of gap junction blocker beta-glycyrrhetinic acid on taste disk cells in frog.
Journal: Cellular and molecular neurobiology20090601
Title: In vitro effects of glycyrrhetinic acid on the growth of clinical isolates of Candida albicans.
Journal: Phytotherapy research : PTR20090401
Title: Locomotor rhythm maintenance: electrical coupling among premotor excitatory interneurons in the brainstem and spinal cord of young Xenopus tadpoles.
Journal: The Journal of physiology20090401
Title: Antihyperglycemic effect of 18 beta-glycyrrhetinic acid, aglycone of glycyrrhizin, on streptozotocin-diabetic rats.
Journal: European journal of pharmacology20090315
Title: Possible participation of chloride ion channels in ATP release from cancer cells in suspension.
Journal: Clinical and experimental pharmacology & physiology20090301
Title: ATP release by cardiac myocytes in a simulated ischaemia model: inhibition by a connexin mimetic and enhancement by an antiarrhythmic peptide.
Journal: European journal of pharmacology20090301
Title: Pharmacological 'cross-inhibition' of connexin hemichannels and swelling activated anion channels.
Journal: Glia20090201
Title: Perturbing plasma membrane hemichannels attenuates calcium signalling in cardiac cells and HeLa cells expressing connexins.
Journal: European journal of cell biology20090201
Title: Selective inhibition of 11beta-hydroxysteroid dehydrogenase 1 by 18alpha-glycyrrhetinic acid but not 18beta-glycyrrhetinic acid.
Journal: The Journal of steroid biochemistry and molecular biology20090201
Title: Neuroprotective effects of glycyrrhizic acid and 18beta-glycyrrhetinic acid in PC12 cells via modulation of the PI3K/Akt pathway.
Journal: Journal of agricultural and food chemistry20090128
Title: The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation.
Journal: Bone20090101
Title: Simultaneous determination of 18alpha- and 18beta-glycyrrhetic acid in human plasma by LC-ESI-MS and its application to pharmacokinetics.
Journal: Biomedical chromatography : BMC20090101
Title: Regulatory effects of myoendothelial gap junction on vascular reactivity after hemorrhagic shock in rats.
Journal: Shock (Augusta, Ga.)20090101
Title: Microbial transformation of 18beta-glycyrrhetinic acid by Cunninghamella elegans and Fusarium lini, and lipoxygenase inhibitory activity of transformed products.
Journal: Natural product research20090101
Title: 18beta-Glycyrrhetinic acid induces apoptotic cell death in SiHa cells and exhibits a synergistic effect against antibiotic anti-cancer drug toxicity.
Journal: Life sciences20080926
Title: Enhanced spontaneous Ca2+ events in endothelial cells reflect signalling through myoendothelial gap junctions in pressurized mesenteric arteries.
Journal: Cell calcium20080801
Title: Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways.
Journal: Hepatology (Baltimore, Md.)20080601
Title: Targeting connexin 43 prevents platelet-derived growth factor-BB-induced phenotypic change in porcine coronary artery smooth muscle cells.
Journal: Circulation research20080328
Title: Role of gap junctions and protein kinase A during the development of oocyte maturational competence in Ayu (Plecoglossus altivelis).
Journal: General and comparative endocrinology20080201
Title: Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisites.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology20080201
Title: Role of gap junctions in spontaneous activity of the rat bladder.
Journal: American journal of physiology. Renal physiology20071001
Title: Spontaneous electrical and Ca2+ signals in typical and atypical smooth muscle cells and interstitial cell of Cajal-like cells of mouse renal pelvis.
Journal: The Journal of physiology20070915
Title: Blockade of gap junction coupling by glycyrrhetinic acids in guinea pig cochlear artery: a whole-cell voltage- and current-clamp study.
Journal: British journal of pharmacology20070801
Title: Protein kinase C gamma mutations in the C1B domain cause caspase-3-linked apoptosis in lens epithelial cells through gap junctions.
Journal: Experimental eye research20070701
Title: Primary cultures of chick osteocytes retain functional gap junctions between osteocytes and between osteocytes and osteoblasts.
Journal: Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada20070401
Title: 18alpha-glycyrrhetinic acid induces phenotypic changes of skeletal muscle cells to enter adipogenesis.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20070101
Title: The function of connexin 43 on the differentiation of rat bone marrow cells in culture.
Journal: Biomedical research (Tokyo, Japan)20061201
Title: A gap junction blocker inhibits isolated whole bladder activity in normal rats and rats with partial bladder outlet obstruction.
Journal: Biomedical research (Tokyo, Japan)20061001
Title: The role of connexins in the differentiation of NT2 cells in Sertoli-NT2 cell tissue constructs grown in the rotating wall bioreactor.
Journal: Experimental brain research20060401
Title: Protective effect of gap junction uncouplers given during hypoxia against reoxygenation injury in isolated rat hearts.
Journal: American journal of physiology. Heart and circulatory physiology20060201
Title: Role of gap junctional coupling in astrocytic networks in the determination of global ischaemia-induced oxidative stress and hippocampal damage.
Journal: The European journal of neuroscience20060101
Title: Staphylococcus aureus-derived peptidoglycan induces Cx43 expression and functional gap junction intercellular communication in microglia.
Journal: Journal of neurochemistry20051001
Title: Licorice compounds glycyrrhizin and 18beta-glycyrrhetinic acid are potent modulators of bile acid-induced cytotoxicity in rat hepatocytes.
Journal: The Journal of biological chemistry20050318
Title: Adenoviral delivery of human connexin37 induces endothelial cell death through apoptosis.
Journal: Biochemical and biophysical research communications20040709
Title: Prostaglandin F2alpha amplifies tumor necrosis factor-alpha promoter activity by the FPB prostanoid receptor.
Journal: Biochemical and biophysical research communications20040514
Title: Global, synchronous oscillations in cytosolic calcium and adherence in bradykinin-stimulated Madin-Darby canine kidney cells.
Journal: Acta physiologica Scandinavica20040401
Title: Cytogenetic detection of a trans-species bystander effect: induction of sister chromatid exchanges in murine 3T3 cells by ganciclovir metabolized in HSV thymidine kinase gene-transfected Chinese hamster ovary cells.
Journal: Mutagenesis20040101
Title: Human primary endothelial cells stimulate human osteoprogenitor cell differentiation.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20040101
Title: [Involvement of gap junctions in stimulation of in vitro maturation of the common frog oocytes by low progesterone concentrations].
Journal: Ontogenez20040101
Title: ECM-induced gap junctional communication enhances mammary epithelial cell differentiation.
Journal: Journal of cell science20030901
Title: Intercellular calcium waves mediate preferential cell growth toward the wound edge in polarized hepatic cells.
Journal: Experimental cell research20030715
Title: Functional hemichannels in astrocytes: a novel mechanism of glutamate release.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20030501
Title: Expression of connexin 43 mRNA in microisolated murine osteoclasts and regulation of bone resorption in vitro by gap junction inhibitors.
Journal: Biochemical and biophysical research communications20030418
Title: Blockade of brain stem gap junctions increases phrenic burst frequency and reduces phrenic burst synchronization in adult rat.
Journal: Journal of neurophysiology20030101
Title: Inhibitors of gap junctions attenuate myogenic tone in cerebral arteries.
Journal: American journal of physiology. Heart and circulatory physiology20021201
Title: Bone morphogenetic protein-2 modulation of chondrogenic differentiation in vitro involves gap junction-mediated intercellular communication.
Journal: Journal of cellular physiology20021101
Title: The role of gap junctions in mediating endothelium-dependent responses to bradykinin in myometrial small arteries isolated from pregnant women.
Journal: British journal of pharmacology20020801
Title: Critical role of gap junctions in endothelium-dependent hyperpolarization in rat mesenteric arteries.
Journal: Clinical and experimental pharmacology & physiology20020701
Title: Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries.
Journal: Biochemical and biophysical research communications20020125
Title: Bimodal inhibition of connexin 43 gap junctions decreases ACTH-induced steroidogenesis and increases bovine adrenal cell population growth.
Journal: The Journal of endocrinology20011001
Title: An endothelium-derived hyperpolarizing factor-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of endothelial nitric oxide synthase-derived nitric oxide.
Journal: Hypertension (Dallas, Tex. : 1979)20011001
Title: Dual mechanism of intercellular communication in HOBIT osteoblastic cells: a role for gap-junctional hemichannels.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research20010801
Title: Persistence of gap junction communication during myocardial ischemia.
Journal: American journal of physiology. Heart and circulatory physiology20010601
Title: Endothelium-dependent vasorelaxation independent of nitric oxide and K(+) release in isolated renal arteries of rats.
Journal: British journal of pharmacology20010401
Title: Phytoestrogens inhibit human 17beta-hydroxysteroid dehydrogenase type 5.
Journal: Molecular and cellular endocrinology20010122
Title: Blockade of chloride channels reveals relaxations of rat small mesenteric arteries to raised potassium.
Journal: British journal of pharmacology20010101
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