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Home Amines 145455-35-2
145455-35-2,MFCD00915396
Catalog No.:AA001CZ5

145455-35-2 | Butanamide, 3-[[(2R)-2-hydroxypropyl]amino]-3-methyl-N-[(3R)-2,3,4,5-tetrahydro-2-oxo-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3-yl]-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
99%
1 week  
$320.00   $224.00
- +
10mg
99%
1 week  
$479.00   $335.00
- +
25mg
99%
1 week  
$939.00   $658.00
- +
50mg
99%
1 week  
$1,479.00   $1,035.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001CZ5
Chemical Name:
Butanamide, 3-[[(2R)-2-hydroxypropyl]amino]-3-methyl-N-[(3R)-2,3,4,5-tetrahydro-2-oxo-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3-yl]-
CAS Number:
145455-35-2
Molecular Formula:
C32H37N7O3
Molecular Weight:
567.6813
MDL Number:
MFCD00915396
SMILES:
C[C@H](CNC(CC(=O)N[C@@H]1CCc2c(N(C1=O)Cc1ccc(cc1)c1ccccc1c1[nH]nnn1)cccc2)(C)C)O
Properties
Computed Properties
 
Complexity:
895  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
42  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
10  
XLogP3:
3.8  

Literature

Title: Intracerebroventricular and intravenous administration of growth hormone secretagogue L-692,585, somatostatin, neuropeptide Y and galanin in pig: dose-dependent effects on growth hormone secretion.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100501

Title: Stimulation of growth hormone secretion from seabream pituitary cells in primary culture by growth hormone secretagogues is independent of growth hormone transcription.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041001

Title: Stimulatory effect of ghrelin on isolated porcine somatotropes.

Journal: Neuroendocrinology 20030601

Title: Ghrelin and growth hormone (GH) secretagogues potentiate GH-releasing hormone (GHRH)-induced cyclic adenosine 3',5'-monophosphate production in cells expressing transfected GHRH and GH secretagogue receptors.

Journal: Endocrinology 20021201

Title: Mechanism of action of the growth hormone secretagogue, L-692,585, on isolated porcine somatotropes.

Journal: The Journal of endocrinology 20021201

Title: Smith RG, et, al. Peptidomimetic regulation of growth hormone secretion. Endocr Rev. 1997 Oct; 18(5): 621-45.

Title: Glavaski-Joksimovic A, et, al. Mechanism of action of the growth hormone secretagogue, L-692,585, on isolated porcine somatotropes. J Endocrinol. 2002 Dec; 175(3): 625-36.

Title: Jacks T, et, al. Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles. J Endocrinol. 1994 Nov; 143(2): 399-406.

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Tags:145455-35-2 Molecular Formula|145455-35-2 MDL|145455-35-2 SMILES|145455-35-2 Butanamide, 3-[[(2R)-2-hydroxypropyl]amino]-3-methyl-N-[(3R)-2,3,4,5-tetrahydro-2-oxo-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3-yl]-